omidenepag


SMILES OC(=O)CNc1cccc(n1)CN(S(=O)(=O)c1cccnc1)Cc1ccc(cc1)n1cccn1
InChIKey YHGSTSNEOJUIRN-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 2
Rotatable bonds 10
Molecular weight (Da) 478.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP2 PE2R2 Human Prostanoid A pKi 8.44 8.44 8.44 Guide to Pharmacology
EP2 PE2R2 Human Prostanoid A pKi 8.44 8.44 8.44 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP2 PE2R2 Human Prostanoid A pEC50 8.96 8.96 8.96 ChEMBL
EP2 PE2R2 Human Prostanoid A pIC50 8.0 8.0 8.0 ChEMBL
EP4 PE2R4 Human Prostanoid A pIC50 5.26 5.26 5.26 ChEMBL