CHEMBL26677


SMILES COc1cccc(C(=O)CCCN2CCN(c3ccccc3OC)CC2)c1
InChIKey XGXUWJSIDSMGFX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 8
Molecular weight (Da) 368.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pKi 8.52 8.52 8.52 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.77 8.77 8.77 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 9.11 9.11 9.11 ChEMBL
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 6.96 6.96 6.96 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pIC50 8.51 8.51 8.51 ChEMBL
D2 DRD2 Human Dopamine A pIC50 7.89 7.89 7.89 ChEMBL