CHEMBL270589


SMILES CC(C)Oc1ccccc1N1CCN(C2CCC(NC(=O)Nc3c(F)cccc3F)CC2)CC1
InChIKey GRLCSEWTOACLTP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 472.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 6.52 6.98 7.44 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 7.04 7.68 8.32 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 7.28 7.78 8.28 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.66 8.14 8.62 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 6.52 6.98 7.44 PDSP Ki database
α1D ADA1D Human Adrenoceptors A pKi 7.04 7.73 8.32 PDSP Ki database
D2 DRD2 Human Dopamine A pKi 7.66 8.14 8.62 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database