(R)ZACOPRIDE


SMILES COc1cc(N)c(Cl)cc1C(=O)N[C@H]1CN2CCC1CC2
InChIKey FEROPKNOYKURCJ-ZDUSSCGKSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 309.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT4 5HT4R Rat 5-Hydroxytryptamine A pKi 5.82 5.82 5.82 ChEMBL
5-HT4 5HT4R Guinea pig 5-Hydroxytryptamine A pKi 5.55 5.55 5.55 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT4 5HT4R Rat 5-Hydroxytryptamine A pEC50 6.3 6.3 6.3 ChEMBL
5-HT4 5HT4R Guinea pig 5-Hydroxytryptamine A pEC50 6.78 6.78 6.78 ChEMBL