Compound 24 [Pmid: 23374867]

Chemical Properties

SMILES CCCc1cccc(n1)c1c(snc1c1ccc2c(c1)cn(n2)C)NC(=O)[C@@H]1C[C@H]1C
Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight 431.2

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey DMJNZMXZSQWBRT-RDTXWAMCSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Human Metabotropic glutamate C pIC50 7.72 7.72 7.72 Guide to Pharmacology
mGlu1 GRM1 Human Metabotropic glutamate C pIC50 6.39 6.39 6.39 ChEMBL
mGlu5 GRM5 Human Metabotropic glutamate C pIC50 7.7 7.7 7.7 ChEMBL