CHEMBL28063


SMILES COc1ccccc1N1CCN(CCC(=O)NC2CCCc3c(OC)cccc32)CC1
InChIKey HGOXUQUWFDSTAA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 423.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 6.57 6.57 6.57 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.17 7.17 7.17 ChEMBL
D2 DRD2 Rat Dopamine A pKi 6.6 6.6 6.6 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 6.6 6.6 6.6 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pIC50 6.12 6.12 6.12 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pIC50 7.42 7.42 7.42 ChEMBL