CHEMBL2414356
SMILES | Clc1ccc(-n2cc(CCCN3CCN(c4ccccc4)CC3)cn2)cc1 |
InChIKey | HIFJFKUAMBPYFD-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 4 |
Hydrogen bond donors | 0 |
Rotatable bonds | 6 |
Molecular weight (Da) | 380.2 |
Drug properties
Molecular type | Small molecule |
Physiological/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
α1B | ADA1B | Rat | Adrenoceptors | A | pKi | 6.16 | 6.16 | 6.16 | ChEMBL |
D2 | DRD2 | Rat | Dopamine | A | pKi | 6.17 | 6.17 | 6.17 | ChEMBL |
D4 | DRD4 | Human | Dopamine | A | pKi | 6.48 | 6.48 | 6.48 | ChEMBL |
5-HT1A | 5HT1A | Rat | 5-Hydroxytryptamine | A | pKi | 6.75 | 6.75 | 6.75 | ChEMBL |
5-HT2C | 5HT2C | Human | 5-Hydroxytryptamine | A | pKi | 5.29 | 5.29 | 5.29 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |