CHEMBL241641


SMILES O=C(NCCCCN1CCN(c2cccc(Cl)c2Cl)CC1)c1ccc(C#Cc2ccccc2)cc1
InChIKey IZRFSGDNQRHHKW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 505.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Pig Dopamine A pKi 5.33 5.33 5.33 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.48 6.48 6.48 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.49 8.49 8.49 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.08 6.1 6.11 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database