CHEMBL242724


SMILES COc1cc2nc(N3CCN(C(=O)c4cccs4)[C@H]4CCCC[C@H]43)nc(N)c2cc1OC
InChIKey UIAXVFLURTXSJC-DLBZAZTESA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 453.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1D ADA1D Rat Adrenoceptors A pKd 7.45 7.45 7.45 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 9.62 9.62 9.62 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 8.63 8.63 8.63 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 8.37 8.37 8.37 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database