CHEMBL242934


SMILES COc1cc2nc(N3CCN(C(=O)c4ccccc4)[C@H]4CCCC[C@H]43)nc(N)c2cc1OC
InChIKey LHLZWQUFUNHDHT-VQTJNVASSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 447.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 9.31 9.31 9.31 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKd 7.51 7.51 7.51 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 8.49 8.49 8.49 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 8.38 8.38 8.38 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database