CHEMBL28651


SMILES CSc1ccc(N2CCN(Cc3c[nH]c4ncccc34)CC2)cc1
InChIKey TYDSNTMUQPPTLL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 338.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pKi 7.34 7.34 7.34 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.47 6.47 6.47 ChEMBL
D4 DRD4 Rat Dopamine A pKi 8.33 8.33 8.33 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database