CHEMBL28997


SMILES Fc1ccc(N2CCN(Cc3c[nH]c4ncccc34)CC2)cc1
InChIKey HNCAIEASLRMRKM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 310.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 8.64 8.64 8.64 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.38 6.38 6.38 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.56 5.56 5.56 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.63 6.63 6.63 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database