ADGRV1 (agrv1_human)
FAMILY
Class B2 (Adhesion) Adhesion receptors ADGRV ADGRV1
GENE
ADGRV1 (GPR98, KIAA0686, KIAA1943, MASS1, VLGR1)
ORGANISM
Human (Homo sapiens)
ALT. NAMES
Adhesion G-protein coupled receptor V1, ADGRV1, 3.4.-.-, G-protein coupled receptor 98, Monogenic audiogenic seizure susceptibility protein 1 homolog, Usher syndrome type-2C protein, Very large G-protein coupled receptor 1, ADGRV1 subunit alpha, ADGRV1 subunit beta
SOURCE
SWISSPROT
SEQUENCE
N-term | |||||||||
M
|
S
|
V
|
F
|
L
|
G
|
P
|
G
|
M
|
P
|
10 |
S
|
A
|
S
|
L
|
L
|
V
|
N
|
L
|
L
|
S
|
20 |
A
|
L
|
L
|
I
|
L
|
F
|
V
|
F
|
G
|
E
|
30 |
T
|
E
|
I
|
R
|
F
|
T
|
G
|
Q
|
T
|
E
|
40 |
F
|
V
|
V
|
N
|
E
|
T
|
S
|
T
|
T
|
V
|
50 |
I
|
R
|
L
|
I
|
I
|
E
|
R
|
I
|
G
|
E
|
60 |
P
|
A
|
N
|
V
|
T
|
A
|
I
|
V
|
S
|
L
|
70 |
Y
|
G
|
E
|
D
|
A
|
G
|
D
|
F
|
F
|
D
|
80 |
T
|
Y
|
A
|
A
|
A
|
F
|
I
|
P
|
A
|
G
|
90 |
E
|
T
|
N
|
R
|
T
|
V
|
Y
|
I
|
A
|
V
|
100 |
C
|
D
|
D
|
D
|
L
|
P
|
E
|
P
|
D
|
E
|
110 |
T
|
F
|
I
|
F
|
H
|
L
|
T
|
L
|
Q
|
K
|
120 |
P
|
S
|
A
|
N
|
V
|
K
|
L
|
G
|
W
|
P
|
130 |
R
|
T
|
V
|
T
|
V
|
T
|
I
|
L
|
S
|
N
|
140 |
D
|
N
|
A
|
F
|
G
|
I
|
I
|
S
|
F
|
N
|
150 |
M
|
L
|
P
|
S
|
I
|
A
|
V
|
S
|
E
|
P
|
160 |
K
|
G
|
R
|
N
|
E
|
S
|
M
|
P
|
L
|
T
|
170 |
L
|
I
|
R
|
E
|
K
|
G
|
T
|
Y
|
G
|
M
|
180 |
V
|
M
|
V
|
T
|
F
|
E
|
V
|
E
|
G
|
G
|
190 |
P
|
N
|
P
|
P
|
D
|
E
|
D
|
L
|
S
|
P
|
200 |
V
|
K
|
G
|
N
|
I
|
T
|
F
|
P
|
P
|
G
|
210 |
R
|
A
|
T
|
V
|
I
|
Y
|
N
|
L
|
T
|
V
|
220 |
L
|
D
|
D
|
E
|
V
|
P
|
E
|
N
|
D
|
E
|
230 |
I
|
F
|
L
|
I
|
Q
|
L
|
K
|
S
|
V
|
E
|
240 |
G
|
G
|
A
|
E
|
I
|
N
|
T
|
S
|
R
|
N
|
250 |
S
|
I
|
E
|
I
|
I
|
I
|
K
|
K
|
N
|
D
|
260 |
S
|
P
|
V
|
R
|
F
|
L
|
Q
|
S
|
I
|
Y
|
270 |
L
|
V
|
P
|
E
|
E
|
D
|
H
|
I
|
L
|
I
|
280 |
I
|
P
|
V
|
V
|
R
|
G
|
K
|
D
|
N
|
N
|
290 |
G
|
N
|
L
|
I
|
G
|
S
|
D
|
E
|
Y
|
E
|
300 |
V
|
S
|
I
|
S
|
Y
|
A
|
V
|
T
|
T
|
G
|
310 |
N
|
S
|
T
|
A
|
H
|
A
|
Q
|
Q
|
N
|
L
|
320 |
D
|
F
|
I
|
D
|
L
|
Q
|
P
|
N
|
T
|
T
|
330 |
V
|
V
|
F
|
P
|
P
|
F
|
I
|
H
|
E
|
S
|
340 |
H
|
L
|
K
|
F
|
Q
|
I
|
V
|
D
|
D
|
T
|
350 |
I
|
P
|
E
|
I
|
A
|
E
|
S
|
F
|
H
|
I
|
360 |
M
|
L
|
L
|
K
|
D
|
T
|
L
|
Q
|
G
|
D
|
370 |
A
|
V
|
L
|
I
|
S
|
P
|
S
|
V
|
V
|
Q
|
380 |
V
|
T
|
I
|
K
|
P
|
N
|
D
|
K
|
P
|
Y
|
390 |
G
|
V
|
L
|
S
|
F
|
N
|
S
|
V
|
L
|
F
|
400 |
E
|
R
|
T
|
V
|
I
|
I
|
D
|
E
|
D
|
R
|
410 |
I
|
S
|
R
|
Y
|
E
|
E
|
I
|
T
|
V
|
V
|
420 |
R
|
N
|
G
|
G
|
T
|
H
|
G
|
N
|
V
|
S
|
430 |
A
|
N
|
W
|
V
|
L
|
T
|
R
|
N
|
S
|
T
|
440 |
D
|
P
|
S
|
P
|
V
|
T
|
A
|
D
|
I
|
R
|
450 |
P
|
S
|
S
|
G
|
V
|
L
|
H
|
F
|
A
|
Q
|
460 |
G
|
Q
|
M
|
L
|
A
|
T
|
I
|
P
|
L
|
T
|
470 |
V
|
V
|
D
|
D
|
D
|
L
|
P
|
E
|
E
|
A
|
480 |
E
|
A
|
Y
|
L
|
L
|
Q
|
I
|
L
|
P
|
H
|
490 |
T
|
I
|
R
|
G
|
G
|
A
|
E
|
V
|
S
|
E
|
500 |
P
|
A
|
E
|
L
|
L
|
F
|
Y
|
I
|
Q
|
D
|
510 |
S
|
D
|
D
|
V
|
Y
|
G
|
L
|
I
|
T
|
F
|
520 |
F
|
P
|
M
|
E
|
N
|
Q
|
K
|
I
|
E
|
S
|
530 |
S
|
P
|
G
|
E
|
R
|
Y
|
L
|
S
|
L
|
S
|
540 |
F
|
T
|
R
|
L
|
G
|
G
|
T
|
K
|
G
|
D
|
550 |
V
|
R
|
L
|
L
|
Y
|
S
|
V
|
L
|
Y
|
I
|
560 |
P
|
A
|
G
|
A
|
V
|
D
|
P
|
L
|
Q
|
A
|
570 |
K
|
E
|
G
|
I
|
L
|
N
|
I
|
S
|
R
|
R
|
580 |
N
|
D
|
L
|
I
|
F
|
P
|
E
|
Q
|
K
|
T
|
590 |
Q
|
V
|
T
|
T
|
K
|
L
|
P
|
I
|
R
|
N
|
600 |
D
|
A
|
F
|
L
|
Q
|
N
|
G
|
A
|
H
|
F
|
610 |
L
|
V
|
Q
|
L
|
E
|
T
|
V
|
E
|
L
|
L
|
620 |
N
|
I
|
I
|
P
|
L
|
I
|
P
|
P
|
I
|
S
|
630 |
P
|
R
|
F
|
G
|
E
|
I
|
C
|
N
|
I
|
S
|
640 |
L
|
L
|
V
|
T
|
P
|
A
|
I
|
A
|
N
|
G
|
650 |
E
|
I
|
G
|
F
|
L
|
S
|
N
|
L
|
P
|
I
|
660 |
I
|
L
|
H
|
E
|
P
|
E
|
D
|
F
|
A
|
A
|
670 |
E
|
V
|
V
|
Y
|
I
|
P
|
L
|
H
|
R
|
D
|
680 |
G
|
T
|
D
|
G
|
Q
|
A
|
T
|
V
|
Y
|
W
|
690 |
S
|
L
|
K
|
P
|
S
|
G
|
F
|
N
|
S
|
K
|
700 |
A
|
V
|
T
|
P
|
D
|
D
|
I
|
G
|
P
|
F
|
710 |
N
|
G
|
S
|
V
|
L
|
F
|
L
|
S
|
G
|
Q
|
720 |
S
|
D
|
T
|
T
|
I
|
N
|
I
|
T
|
I
|
K
|
730 |
G
|
D
|
D
|
I
|
P
|
E
|
M
|
N
|
E
|
T
|
740 |
V
|
T
|
L
|
S
|
L
|
D
|
R
|
V
|
N
|
V
|
750 |
E
|
N
|
Q
|
V
|
L
|
K
|
S
|
G
|
Y
|
T
|
760 |
S
|
R
|
D
|
L
|
I
|
I
|
L
|
E
|
N
|
D
|
770 |
D
|
P
|
G
|
G
|
V
|
F
|
E
|
F
|
S
|
P
|
780 |
A
|
S
|
R
|
G
|
P
|
Y
|
V
|
I
|
K
|
E
|
790 |
G
|
E
|
S
|
V
|
E
|
L
|
H
|
I
|
I
|
R
|
800 |
S
|
R
|
G
|
S
|
L
|
V
|
K
|
Q
|
F
|
L
|
810 |
H
|
Y
|
R
|
V
|
E
|
P
|
R
|
D
|
S
|
N
|
820 |
E
|
F
|
Y
|
G
|
N
|
T
|
G
|
V
|
L
|
E
|
830 |
F
|
K
|
P
|
G
|
E
|
R
|
E
|
I
|
V
|
I
|
840 |
T
|
L
|
L
|
A
|
R
|
L
|
D
|
G
|
I
|
P
|
850 |
E
|
L
|
D
|
E
|
H
|
Y
|
W
|
V
|
V
|
L
|
860 |
S
|
S
|
H
|
G
|
E
|
R
|
E
|
S
|
K
|
L
|
870 |
G
|
S
|
A
|
T
|
I
|
V
|
N
|
I
|
T
|
I
|
880 |
L
|
K
|
N
|
D
|
D
|
P
|
H
|
G
|
I
|
I
|
890 |
E
|
F
|
V
|
S
|
D
|
G
|
L
|
I
|
V
|
M
|
900 |
I
|
N
|
E
|
S
|
K
|
G
|
D
|
A
|
I
|
Y
|
910 |
S
|
A
|
V
|
Y
|
D
|
V
|
V
|
R
|
N
|
R
|
920 |
G
|
N
|
F
|
G
|
D
|
V
|
S
|
V
|
S
|
W
|
930 |
V
|
V
|
S
|
P
|
D
|
F
|
T
|
Q
|
D
|
V
|
940 |
F
|
P
|
V
|
Q
|
G
|
T
|
V
|
V
|
F
|
G
|
950 |
D
|
Q
|
E
|
F
|
S
|
K
|
N
|
I
|
T
|
I
|
960 |
Y
|
S
|
L
|
P
|
D
|
E
|
I
|
P
|
E
|
E
|
970 |
M
|
E
|
E
|
F
|
T
|
V
|
I
|
L
|
L
|
N
|
980 |
G
|
T
|
G
|
G
|
A
|
K
|
V
|
G
|
N
|
R
|
990 |
T
|
T
|
A
|
T
|
L
|
R
|
I
|
R
|
R
|
N
|
1000 |
D
|
D
|
P
|
I
|
Y
|
F
|
A
|
E
|
P
|
R
|
1010 |
V
|
V
|
R
|
V
|
Q
|
E
|
G
|
E
|
T
|
A
|
1020 |
N
|
F
|
T
|
V
|
L
|
R
|
N
|
G
|
S
|
V
|
1030 |
D
|
V
|
T
|
C
|
M
|
V
|