MAS1 (mas_human)
FAMILY
Class A (Rhodopsin) Orphan receptors Class A orphans MAS1
GENE
MAS1 (MAS)
ORGANISM
Human (Homo sapiens)
ALT. NAMES
Proto-oncogene Mas
SOURCE
SWISSPROT
SEQUENCE
N-term | |||||||||
M
|
D
|
G
|
S
|
N
|
V
|
T
|
S
|
F
|
V
|
10 |
V
|
E
|
E
|
P
|
T
|
N
|
I
|
S
|
T
|
G
|
20 |
R
|
N
|
A
|
S
|
V
|
G
|
N
|
A
|
H
|
R
|
30 |
TM1 | |||||||||
Q
|
I
|
P
|
I
|
V
|
H
|
W
|
V
|
I
|
M
|
40 |
S
|
I
|
S
|
P
|
V
|
G
|
F
|
V
|
E
|
N
|
50 |
G
|
I
|
L
|
L
|
W
|
F
|
L
|
C
|
F
|
R
|
60 |
ICL1 | TM2 | ||||||||
M
|
R
|
R
|
N
|
P
|
F
|
T
|
V
|
Y
|
I
|
70 |
T
|
H
|
L
|
S
|
I
|
A
|
D
|
I
|
S
|
L
|
80 |
L
|
F
|
C
|
I
|
F
|
I
|
L
|
S
|
I
|
D
|
90 |
ECL1 | TM3 | |||||||||
Y
|
A
|
L
|
D
|
Y
|
E
|
L
|
S
|
S
|
G
|
|
100 |
H
|
Y
|
Y
|
T
|
I
|
V
|
T
|
L
|
S
|
V
|
110 |
T
|
F
|
L
|
F
|
G
|
Y
|
N
|
T
|
G
|
L
|
120 |
Y
|
L
|
L
|
T
|
A
|
I
|
S
|
V
|
E
|
R
|
130 |
ICL2 | |||||||||
C
|
L
|
S
|
V
|
L
|
Y
|
P
|
I
|
W
|
Y
|
140 |
TM4 | |||||||||
R
|
C
|
H
|
R
|
P
|
K
|
Y
|
Q
|
S
|
A
|
150 |
L
|
V
|
C
|
A
|
L
|
L
|
W
|
A
|
L
|
S
|
160 |
C
|
L
|
V
|
T
|
T
|
M
|
E
|
Y
|
V
|
M
|
170 |
ECL2 | |||||||||
C
|
I
|
D
|
R
|
E
|
E
|
E
|
S
|
H
|
S
|
180 |
TM5 | |||||||||
R
|
N
|
D
|
C
|
R
|
A
|
V
|
I
|
I
|
F
|
190 |
I
|
A
|
I
|
L
|
S
|
F
|
L
|
V
|
F
|
T
|
200 |
P
|
L
|
M
|
L
|
V
|
S
|
S
|
T
|
I
|
L
|
210 |
V
|
V
|
K
|
I
|
R
|
K
|
N
|
T
|
W
|
A
|
220 |
ICL3 | TM6 | ||||||||
S
|
H
|
S
|
S
|
K
|
L
|
Y
|
I
|
V
|
I
|
230 |
M
|
V
|
T
|
I
|
I
|
I
|
F
|
L
|
I
|
F
|
240 |
A
|
M
|
P
|
M
|
R
|
L
|
L
|
Y
|
L
|
L
|
250 |
ECL3 | |||||||||
Y
|
Y
|
E
|
Y
|
W
|
S
|
T
|
F
|
G
|
N
|
260 |
TM7 | |||||||||
L
|
H
|
H
|
I
|
S
|
L
|
L
|
F
|
S
|
T
|
270 |
I
|
N
|
S
|
S
|
A
|
N
|
P
|
F
|
I
|
Y
|
280 |
H8 | |||||||||
F
|
F
|
V
|
G
|
S
|
S
|
K
|
K
|
K
|
R
|
290 |
F
|
K
|
E
|
S
|
L
|
K
|
V
|
V
|
L
|
T
|
300 |
C-term | |||||||||
R
|
A
|
F
|
K
|
D
|
E
|
M
|
Q
|
P
|
R
|
310 |
R
|
Q
|
K
|
D
|
N
|
C
|
N
|
T
|
V
|
T
|
320 |
V
|
E
|
T
|
V
|
V
|
LINKS
DIAGRAMS
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
MUTATIONS
PHYSIOLOGICAL LIGANDS
No physiological ligands available
STRUCTURE MODELS
STRUCTURES
No structures available