OR14A2 (o14a2_human)
FAMILY
Class O2 (tetrapod specific odorant) Odorant receptors Odorant family 14 OR14A2
GENE
OR14A2 (OR5AX1, OR5AX1P)
ORGANISM
Human (Homo sapiens)
ALT. NAMES
Olfactory receptor 14A2, Olfactory receptor 5AX1, Olfactory receptor OR1-31
SOURCE
SWISSPROT
SEQUENCE
N-term | |||||||||
M
|
A
|
N
|
V
|
T
|
L
|
V
|
T
|
G
|
F
|
10 |
TM1 | |||||||||
L
|
L
|
M
|
G
|
F
|
S
|
N
|
I
|
Q
|
K
|
20 |
L
|
R
|
I
|
L
|
Y
|
G
|
V
|
L
|
F
|
L
|
30 |
L
|
I
|
Y
|
L
|
A
|
A
|
L
|
M
|
S
|
N
|
40 |
L
|
L
|
I
|
I
|
T
|
L
|
I
|
T
|
L
|
D
|
50 |
ICL1 | TM2 | ||||||||
V
|
K
|
L
|
Q
|
T
|
P
|
M
|
Y
|
F
|
F
|
60 |
L
|
K
|
N
|
L
|
S
|
F
|
L
|
D
|
V
|
F
|
70 |
L
|
V
|
S
|
V
|
P
|
I
|
P
|
K
|
F
|
I
|
80 |
ECL1 | |||||||||
V
|
N
|
N
|
L
|
T
|
H
|
N
|
N
|
S
|
I
|
90 |
TM3 | |||||||||
S
|
I
|
L
|
G
|
C
|
A
|
F
|
Q
|
L
|
L
|
100 |
L
|
M
|
T
|
S
|
F
|
S
|
A
|
G
|
E
|
I
|
110 |
F
|
I
|
L
|
T
|
A
|
M
|
S
|
Y
|
D
|
R
|
120 |
ICL2 | |||||||||
Y
|
V
|
A
|
I
|
C
|
C
|
P
|
L
|
N
|
Y
|
130 |
TM4 | |||||||||
E
|
V
|
I
|
M
|
N
|
T
|
G
|
V
|
C
|
V
|
140 |
L
|
M
|
A
|
S
|
V
|
S
|
W
|
A
|
I
|
G
|
150 |
G
|
L
|
F
|
G
|
T
|
A
|
Y
|
T
|
A
|
G
|
160 |
ECL2 | |||||||||
T
|
F
|
S
|
M
|
P
|
F
|
C
|
G
|
S
|
S
|
170 |
V
|
I
|
P
|
Q
|
F
|
F
|
C
|
D
|
V
|
P
|
180 |
S
|
L
|
L
|
R
|
I
|
S
|
C
|
S
|
E
|
T
|
190 |
TM5 | |||||||||
L
|
M
|
V
|
I
|
Y
|
A
|
G
|
I
|
G
|
V
|
200 |
G
|
A
|
C
|
L
|
S
|
I
|
S
|
C
|
F
|
I
|
210 |
C
|
I
|
V
|
I
|
S
|
Y
|
I
|
Y
|
I
|
F
|
220 |
ICL3 | TM6 | |||||||||
S
|
T
|
V
|
L
|
K
|
I
|
P
|
T
|
T
|
K
|
|
230 |
G
|
Q
|
S
|
K
|
A
|
F
|
S
|
T
|
C
|
F
|
240 |
P
|
H
|
L
|
T
|
V
|
F
|
T
|
V
|
F
|
I
|
250 |
I
|
T
|
A
|
Y
|
F
|
V
|
Y
|
L
|
K
|
P
|
260 |
ECL3 | TM7 | ||||||||
P
|
S
|
N
|
S
|
P
|
S
|
V
|
I
|
D
|
R
|
270 |
L
|
L
|
S
|
V
|
I
|
Y
|
T
|
V
|
M
|
P
|
280 |
P
|
V
|
F
|
N
|
P
|
V
|
T
|
Y
|
S
|
L
|
290 |
H8 | |||||||||
R
|
N
|
N
|
D
|
M
|
K
|
C
|
A
|
L
|
I
|
300 |
R
|
L
|
L
|
Q
|
K
|
T
|
Y
|
G
|
Q
|
E
|
310 |
C-term | ||||||
A
|
Y
|
F
|
I
|
|||
LINKS
DIAGRAMS
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
MUTATIONS
PHYSIOLOGICAL LIGANDS
No physiological ligands available
STRUCTURE MODELS
STRUCTURES
No structures available