OR52E8 (o52e8_human)
FAMILY
Class O1 (fish-like odorant) Odorant receptors Odorant family 52 OR52E8
GENE
OR52E8
ORGANISM
Human (Homo sapiens)
ALT. NAMES
Olfactory receptor 52E8, Olfactory receptor OR11-54
SOURCE
SWISSPROT
SEQUENCE
N-term | |||||||||
M
|
S
|
T
|
S
|
N
|
H
|
T
|
Q
|
F
|
H
|
10 |
P
|
S
|
S
|
F
|
L
|
L
|
L
|
G
|
I
|
P
|
20 |
TM1 | |||||||||
G
|
L
|
E
|
D
|
V
|
H
|
I
|
W
|
I
|
G
|
30 |
V
|
P
|
F
|
F
|
F
|
V
|
Y
|
L
|
V
|
A
|
40 |
L
|
L
|
G
|
N
|
T
|
A
|
L
|
L
|
F
|
V
|
50 |
ICL1 | |||||||||
I
|
Q
|
T
|
E
|
Q
|
S
|
L
|
H
|
E
|
P
|
60 |
TM2 | |||||||||
M
|
Y
|
Y
|
F
|
L
|
A
|
M
|
L
|
D
|
S
|
70 |
I
|
D
|
L
|
G
|
L
|
S
|
T
|
A
|
T
|
I
|
80 |
P
|
K
|
M
|
L
|
G
|
I
|
F
|
W
|
F
|
N
|
90 |
ECL1 | TM3 | ||||||||
T
|
K
|
E
|
I
|
S
|
F
|
G
|
G
|
C
|
L
|
100 |
S
|
H
|
M
|
F
|
F
|
I
|
H
|
F
|
F
|
T
|
110 |
A
|
M
|
E
|
S
|
I
|
V
|
L
|
V
|
A
|
M
|
120 |
A
|
F
|
D
|
R
|
Y
|
I
|
A
|
I
|
C
|
K
|
130 |
ICL2 | |||||||||
P
|
L
|
R
|
Y
|
T
|
M
|
I
|
L
|
T
|
S
|
140 |
TM4 | |||||||||
K
|
I
|
I
|
S
|
L
|
I
|
A
|
G
|
I
|
A
|
150 |
V
|
L
|
R
|
S
|
L
|
Y
|
M
|
V
|
V
|
P
|
160 |
L
|
V
|
F
|
L
|
L
|
L
|
R
|
L
|
P
|
F
|
170 |
ECL2 | |||||||||
C
|
G
|
H
|
R
|
I
|
I
|
P
|
H
|
T
|
Y
|
180 |
C
|
E
|
H
|
M
|
G
|
I
|
A
|
R
|
L
|
A
|
190 |
TM5 | |||||||||
C
|
A
|
S
|
I
|
K
|
V
|
N
|
I
|
R
|
F
|
200 |
G
|
L
|
G
|
N
|
I
|
S
|
L
|
L
|
L
|
L
|
210 |
D
|
V
|
I
|
L
|
I
|
I
|
L
|
S
|
Y
|
V
|
220 |
R
|
I
|
L
|
Y
|
A
|
V
|
F
|
C
|
L
|
P
|
230 |
TM6 | |||||||||
S
|
W
|
E
|
A
|
R
|
L
|
K
|
A
|
L
|
N
|
240 |
T
|
C
|
G
|
S
|
H
|
I
|
G
|
V
|
I
|
L
|
250 |
A
|
F
|
F
|
T
|
P
|
A
|
F
|
F
|
S
|
F
|
260 |
ECL3 | |||||||||
L
|
T
|
H
|
R
|
F
|
G
|
H
|
N
|
I
|
P
|
270 |
TM7 | |||||||||
Q
|
Y
|
I
|
H
|
I
|
I
|
L
|
A
|
N
|
L
|
280 |
Y
|
V
|
V
|
V
|
P
|
P
|
A
|
L
|
N
|
P
|
290 |
H8 | |||||||||
V
|
I
|
Y
|
G
|
V
|
R
|
T
|
K
|
Q
|
I
|
300 |
R
|
E
|
R
|
V
|
L
|
R
|
I
|
F
|
L
|
K
|
310 |
C-term | |||||
T
|
N
|
H
|
|||
LINKS
DIAGRAMS
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
MUTATIONS
PHYSIOLOGICAL LIGANDS
No physiological ligands available
STRUCTURE MODELS
STRUCTURES
No structures available