OR2H2 (or2h2_human)
FAMILY
Class O2 (tetrapod specific odorant) Odorant receptors Odorant family 2 OR2H2
GENE
OR2H2 (FAT11, OLFR2, OR2H3)
ORGANISM
Human (Homo sapiens)
ALT. NAMES
Olfactory receptor 2H2, Hs6M1-12, Olfactory receptor 2H3, Olfactory receptor-like protein FAT11
SOURCE
SWISSPROT
SEQUENCE
N-term | |||||||||
M
|
V
|
N
|
Q
|
S
|
S
|
T
|
P
|
G
|
F
|
10 |
TM1 | |||||||||
L
|
L
|
L
|
G
|
F
|
S
|
E
|
H
|
P
|
G
|
20 |
L
|
E
|
R
|
T
|
L
|
F
|
V
|
V
|
V
|
L
|
30 |
T
|
S
|
Y
|
L
|
L
|
T
|
L
|
V
|
G
|
N
|
40 |
T
|
L
|
I
|
I
|
L
|
L
|
S
|
A
|
L
|
D
|
50 |
ICL1 | TM2 | ||||||||
P
|
K
|
L
|
H
|
S
|
P
|
M
|
Y
|
F
|
F
|
60 |
L
|
S
|
N
|
L
|
S
|
F
|
L
|
D
|
L
|
C
|
70 |
F
|
T
|
T
|
S
|
C
|
V
|
P
|
Q
|
M
|
L
|
80 |
ECL1 | |||||||||
V
|
N
|
L
|
W
|
G
|
P
|
K
|
K
|
T
|
I
|
90 |
TM3 | |||||||||
S
|
F
|
L
|
D
|
C
|
S
|
V
|
Q
|
I
|
F
|
100 |
I
|
F
|
L
|
S
|
L
|
G
|
T
|
T
|
E
|
C
|
110 |
I
|
L
|
L
|
T
|
V
|
M
|
A
|
F
|
D
|
R
|
120 |
ICL2 | |||||||||
Y
|
V
|
A
|
V
|
C
|
Q
|
P
|
L
|
H
|
Y
|
130 |
TM4 | |||||||||
A
|
T
|
I
|
I
|
H
|
P
|
R
|
L
|
C
|
W
|
140 |
Q
|
L
|
A
|
S
|
V
|
A
|
W
|
V
|
I
|
G
|
150 |
L
|
V
|
E
|
S
|
V
|
V
|
Q
|
T
|
P
|
S
|
160 |
ECL2 | |||||||||
T
|
L
|
H
|
L
|
P
|
F
|
C
|
P
|
D
|
R
|
170 |
Q
|
V
|
D
|
D
|
F
|
V
|
C
|
E
|
V
|
P
|
180 |
A
|
L
|
I
|
R
|
L
|
S
|
C
|
E
|
D
|
T
|
190 |
TM5 | |||||||||
S
|
Y
|
N
|
E
|
I
|
Q
|
V
|
A
|
V
|
A
|
200 |
S
|
V
|
F
|
I
|
L
|
V
|
V
|
P
|
L
|
S
|
210 |
L
|
I
|
L
|
V
|
S
|
Y
|
G
|
A
|
I
|
T
|
220 |
ICL3 | TM6 | ||||||||||
W
|
A
|
V
|
L
|
R
|
I
|
N
|
S
|
A
|
K
|
||
230 |
G
|
R
|
R
|
K
|
A
|
F
|
G
|
T
|
C
|
S
|
240 |
S
|
H
|
L
|
T
|
V
|
V
|
T
|
L
|
F
|
Y
|
250 |
S
|
S
|
V
|
I
|
A
|
V
|
Y
|
L
|
Q
|
P
|
260 |
ECL3 | TM7 | ||||||||
K
|
N
|
P
|
Y
|
A
|
Q
|
E
|
R
|
G
|
K
|
270 |
F
|
F
|
G
|
L
|
F
|
Y
|
A
|
V
|
G
|
T
|
280 |
P
|
S
|
L
|
N
|
P
|
L
|
I
|
Y
|
T
|
L
|
290 |
H8 | |||||||||
R
|
N
|
K
|
E
|
V
|
T
|
R
|
A
|
F
|
R
|
300 |
C-term | |||||||||
R
|
L
|
L
|
G
|
K
|
E
|
M
|
G
|
L
|
T
|
310 |
Q
|
S
|
LINKS
DIAGRAMS
7TM
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
MUTATIONS
PHYSIOLOGICAL LIGANDS
No physiological ligands available
STRUCTURE MODELS
STRUCTURES
No structures available