OR3A3 (or3a3_human)

FAMILY

Class O2 (tetrapod specific odorant) Odorant receptors Odorant family 3 OR3A3

GENE

OR3A3 (OR3A6, OR3A7, OR3A8P)

ORGANISM

Human (Homo sapiens)

ALT. NAMES

Olfactory receptor 3A3, Olfactory receptor 17-201, OR17-201, Olfactory receptor 3A6, Olfactory receptor 3A7, Olfactory receptor 3A8, Olfactory receptor OR17-22

SOURCE

SWISSPROT

SEQUENCE

N-term        
M
S
L
Q
K
L
M
E
P
E
10
                   
A
G
T
N
R
T
A
V
A
E
20
                   
F
I
L
L
G
L
V
Q
T
E
30
TM1              
E
M
Q
P
V
V
F
V
L
L
40
                   
L
F
A
Y
L
V
T
T
G
G
50
                   
N
L
S
I
L
A
A
V
L
V
60
  ICL1 TM2    
E
P
K
L
H
A
P
M
Y
F
70
                   
F
L
G
N
L
S
V
L
D
V
80
                   
G
C
I
T
V
T
V
P
A
M
90
                   
L
G
R
L
L
S
H
K
S
T
100
ECL1 TM3      
I
S
Y
D
A
C
L
S
Q
L
110
                   
F
F
F
H
L
L
A
G
M
D
120
                   
C
F
L
L
T
A
M
A
Y
D
130
                   
R
L
L
A
I
C
Q
P
L
T
140
ICL2   TM4    
Y
S
T
R
M
S
Q
T
V
Q
150
                   
R
M
L
V
A
A
S
W
A
C
160
                   
A
F
T
N
A
L
T
H
T
V
170
        ECL2    
A
M
S
T
L
N
F
C
G
P
180
                   
N
E
V
N
H
F
Y
C
D
L
190
                   
P
Q
L
F
Q
L
S
C
S
S
200
TM5              
T
Q
L
N
E
L
L
L
F
V
210
                   
A
A
A
F
M
A
V
A
P
L
220
                   
V
F
I
S
V
S
Y
A
H
V
230
                   
V
A
A
V
L
Q
I
R
S
A
240
TM6              
E
G
R
K
K
A
F
S
T
C
250
                   
G
S
H
L
T
V
V
G
I
F
260
                   
Y
G
T
G
V
F
S
Y
M
R
270
ECL3     TM7  
L
G
S
V
E
S
S
D
K
D
280
                   
K
G
V
G
V
F
M
T
V
I
290
                   
N
P
M
L
N
P
L
I
Y
S
300
    H8            
L
R
N
T
D
V
Q
G
A
L
310
                   
C
Q
L
L
V
G
K
R
S
L
320
C-term
T

LINKS

UniProt

DIAGRAMS

7TM

ICL1 P K L H ICL1ECL1 K S T I ECL1ICL2 P L T Y S T R M ICL2ECL2 L N F C G P N E V N H F Y C D L P Q L F Q L S C S S ECL2ICL3 R ICL3ECL3 R L G S V E S ECL3N-term M S L Q K L M E P E A G T N R T A V A E F I L L G L V Q N-termC-term K R S L T C-term T E E M Q P V V F V L L L F A Y L V T T G G N L S I L A A V L V E A P M Y F F L G N L S V L D V G C I T V T V P A M L G R L L S H S Y D A C L S Q L F F F H L L A G M D C F L L T A M A Y D R L L A I C Q S Q T V Q R M L V A A S W A C A F T N A L T H T V A M S T T Q L N E L L L F V A A A F M A V A P L V F I S V S Y A H V V A A V L Q I S A E G R K K A F S T C G S H L T V V G I F Y G T G V F S Y M S D K D K G V G V F M T V I N P M L N P L I Y S L R N T D L C Q V Q G A L L V G
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Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A

L N G G T T V L Y A F L L L V F V V P Q 1 G N L S V L D V G C I T V T V P A M L G 2 A T L L F C D M G A L L H F F F L Q S L 3 Q R M L V A A S W A C A F T N A L T H T 4 Y S V S I F V L P A V A M F A A A V F L 5 G S H L T V V G I F Y G T G V F S Y M 6 L P N L M P N I V T M F V G V G K D K 7
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Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A

MUTATIONS

0 mutation data points available.

PHYSIOLOGICAL LIGANDS

No physiological ligands available

STRUCTURE MODELS

or3a3_human inactive,

or3a3_human active

STRUCTURES

No structures available