OR4A5 (or4a5_human)
FAMILY
Class O2 (tetrapod specific odorant) Odorant receptors Odorant family 4 OR4A5
GENE
OR4A5
ORGANISM
Human (Homo sapiens)
ALT. NAMES
Olfactory receptor 4A5, Olfactory receptor OR11-111
SOURCE
SWISSPROT
SEQUENCE
N-term | |||||||||
M
|
R
|
Q
|
N
|
N
|
N
|
I
|
T
|
E
|
F
|
10 |
TM1 | |||||||||
V
|
L
|
L
|
G
|
F
|
S
|
Q
|
D
|
P
|
G
|
20 |
V
|
Q
|
K
|
A
|
L
|
F
|
V
|
M
|
F
|
L
|
30 |
L
|
T
|
Y
|
L
|
V
|
T
|
V
|
V
|
G
|
N
|
40 |
L
|
L
|
I
|
V
|
V
|
D
|
I
|
I
|
A
|
S
|
50 |
ICL1 | TM2 | ||||||||
P
|
S
|
L
|
G
|
S
|
P
|
M
|
Y
|
F
|
F
|
60 |
L
|
A
|
C
|
L
|
S
|
F
|
I
|
D
|
A
|
A
|
70 |
Y
|
S
|
T
|
T
|
I
|
S
|
P
|
K
|
L
|
I
|
80 |
ECL1 | |||||||||
V
|
G
|
L
|
F
|
C
|
D
|
K
|
K
|
T
|
I
|
90 |
TM3 | |||||||||
S
|
F
|
Q
|
G
|
C
|
M
|
G
|
Q
|
L
|
F
|
100 |
I
|
D
|
H
|
F
|
F
|
G
|
G
|
A
|
E
|
V
|
110 |
F
|
L
|
L
|
V
|
V
|
M
|
A
|
C
|
D
|
R
|
120 |
ICL2 | |||||||||
Y
|
V
|
A
|
I
|
C
|
K
|
P
|
L
|
H
|
Y
|
130 |
TM4 | |||||||||
L
|
T
|
I
|
M
|
N
|
R
|
Q
|
V
|
C
|
F
|
140 |
L
|
L
|
L
|
V
|
V
|
A
|
M
|
I
|
G
|
G
|
150 |
F
|
V
|
H
|
S
|
A
|
F
|
Q
|
I
|
V
|
V
|
160 |
ECL2 | |||||||||
Y
|
S
|
L
|
P
|
F
|
C
|
G
|
P
|
N
|
V
|
170 |
I
|
V
|
H
|
F
|
S
|
C
|
D
|
M
|
H
|
P
|
180 |
L
|
L
|
E
|
L
|
A
|
C
|
T
|
D
|
T
|
Y
|
190 |
TM5 | |||||||||
F
|
I
|
G
|
L
|
T
|
V
|
V
|
V
|
N
|
S
|
200 |
G
|
A
|
I
|
C
|
M
|
V
|
I
|
F
|
N
|
L
|
210 |
L
|
L
|
I
|
S
|
Y
|
G
|
V
|
I
|
L
|
S
|
220 |
TM6 | |||||||||
S
|
L
|
K
|
T
|
Y
|
S
|
Q
|
E
|
K
|
R
|
230 |
G
|
K
|
A
|
L
|
S
|
T
|
C
|
S
|
S
|
G
|
240 |
S
|
T
|
V
|
V
|
V
|
L
|
F
|
F
|
V
|
P
|
250 |
ECL3 | |||||||||
C
|
I
|
F
|
I
|
Y
|
V
|
R
|
P
|
V
|
S
|
260 |
TM7 | |||||||||
N
|
F
|
P
|
T
|
D
|
K
|
F
|
M
|
T
|
V
|
270 |
F
|
Y
|
T
|
I
|
I
|
T
|
H
|
M
|
L
|
S
|
280 |
H8 | |||||||||
P
|
L
|
I
|
Y
|
T
|
L
|
R
|
N
|
S
|
E
|
290 |
M
|
R
|
N
|
A
|
I
|
E
|
K
|
L
|
L
|
G
|
300 |
K
|
K
|
L
|
T
|
I
|
F
|
I
|
I
|
G
|
G
|
310 |
C-term | |||||||||
V
|
S
|
V
|
L
|
M
|
|||||
LINKS
DIAGRAMS
7TM
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
MUTATIONS
PHYSIOLOGICAL LIGANDS
No physiological ligands available
STRUCTURE MODELS
STRUCTURES
No structures available