TAAR6 (taar6_human)
FAMILY
Class A (Rhodopsin) Orphan receptors Class A orphans TAAR6
GENE
TAAR6 (TA4, TAR4, TRAR4)
ORGANISM
Human (Homo sapiens)
ALT. NAMES
Trace amine-associated receptor 6, TaR-6, Trace amine receptor 6, Trace amine receptor 4, TaR-4
SOURCE
SWISSPROT
SEQUENCE
N-term | |||||||||
M
|
S
|
S
|
N
|
S
|
S
|
L
|
L
|
V
|
A
|
10 |
V
|
Q
|
L
|
C
|
Y
|
A
|
N
|
V
|
N
|
G
|
20 |
TM1 | |||||||||
S
|
C
|
V
|
K
|
I
|
P
|
F
|
S
|
P
|
G
|
30 |
S
|
R
|
V
|
I
|
L
|
Y
|
I
|
V
|
F
|
G
|
40 |
F
|
G
|
A
|
V
|
L
|
A
|
V
|
F
|
G
|
N
|
50 |
L
|
L
|
V
|
M
|
I
|
S
|
I
|
L
|
H
|
F
|
60 |
ICL1 | TM2 | ||||||||
K
|
Q
|
L
|
H
|
S
|
P
|
T
|
N
|
F
|
L
|
70 |
V
|
A
|
S
|
L
|
A
|
C
|
A
|
D
|
F
|
L
|
80 |
V
|
G
|
V
|
T
|
V
|
M
|
P
|
F
|
S
|
M
|
90 |
ECL1 | |||||||||
V
|
R
|
T
|
V
|
E
|
S
|
C
|
W
|
Y
|
F
|
100 |
TM3 | |||||||||
G
|
R
|
S
|
F
|
C
|
T
|
F
|
H
|
T
|
C
|
110 |
C
|
D
|
V
|
A
|
F
|
C
|
Y
|
S
|
S
|
L
|
120 |
F
|
H
|
L
|
C
|
F
|
I
|
S
|
I
|
D
|
R
|
130 |
ICL2 | |||||||||
Y
|
I
|
A
|
V
|
T
|
D
|
P
|
L
|
V
|
Y
|
140 |
TM4 | |||||||||
P
|
T
|
K
|
F
|
T
|
V
|
S
|
V
|
S
|
G
|
150 |
I
|
C
|
I
|
S
|
V
|
S
|
W
|
I
|
L
|
P
|
160 |
L
|
M
|
Y
|
S
|
G
|
A
|
V
|
F
|
Y
|
T
|
170 |
ECL2 | |||||||||
G
|
V
|
Y
|
D
|
D
|
G
|
L
|
E
|
E
|
L
|
180 |
S
|
D
|
A
|
L
|
N
|
C
|
I
|
G
|
G
|
C
|
190 |
TM5 | |||||||||
Q
|
T
|
V
|
V
|
N
|
Q
|
N
|
W
|
V
|
L
|
200 |
T
|
D
|
F
|
L
|
S
|
F
|
F
|
I
|
P
|
T
|
210 |
F
|
I
|
M
|
I
|
I
|
L
|
Y
|
G
|
N
|
I
|
220 |
F
|
L
|
V
|
A
|
R
|
R
|
Q
|
A
|
K
|
K
|
230 |
I
|
E
|
N
|
T
|
G
|
S
|
K
|
T
|
E
|
S
|
240 |
ICL3 | TM6 | ||||||||
S
|
S
|
E
|
S
|
Y
|
K
|
A
|
R
|
V
|
A
|
250 |
R
|
R
|
E
|
R
|
K
|
A
|
A
|
K
|
T
|
L
|
260 |
G
|
V
|
T
|
V
|
V
|
A
|
F
|
M
|
I
|
S
|
270 |
W
|
L
|
P
|
Y
|
S
|
I
|
D
|
S
|
L
|
I
|
280 |
ECL3 | |||||||||
D
|
A
|
F
|
M
|
G
|
F
|
I
|
T
|
P
|
A
|
290 |
TM7 | |||||||||
C
|
I
|
Y
|
E
|
I
|
C
|
C
|
W
|
C
|
A
|
300 |
Y
|
Y
|
N
|
S
|
A
|
M
|
N
|
P
|
L
|
I
|
310 |
H8 | |||||||||
Y
|
A
|
L
|
F
|
Y
|
P
|
W
|
F
|
R
|
K
|
320 |
A
|
I
|
K
|
V
|
I
|
V
|
T
|
G
|
Q
|
V
|
330 |
C-term | |||||||||
L
|
K
|
N
|
S
|
S
|
A
|
T
|
M
|
N
|
L
|
340 |
F
|
S
|
E
|
H
|
I
|
LINKS
DIAGRAMS
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
Pick color:
Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A
MUTATIONS
PHYSIOLOGICAL LIGANDS
No physiological ligands available
STRUCTURE MODELS
STRUCTURES
No structures available