OR51G2 - Gs

GPCR CLASS (FAMILY)

Class O1 (fish-like odorant)

GPCR SPECIES

Homo sapiens

GPCR PREFERRED CHAIN

A

G PROTEIN (FAMILY)

Gs

G PROTEIN SPECIES

Homo sapiens

PDB CODE

RESOLUTION

3.2 Å

REFERENCE

PUBLICATION DATE

Oct. 30, 2024

3D VIEW

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LIGAND INTERACTIONS

LIGANDS

Apo (no ligand) - Apo (no ligand)

PHYSIOLOGICAL LIGANDS

No physiological ligands available



GPCR - G protein interface interactions



The biflare plot is a modified version of a flareplot, where lines are drawn between an inner concentric circle (Gα residues) and an outer concentric circle (GPCR residues) depicting the interface interactions.
Different interaction types are shown with different line types (aromatic - solid, hydrophobic - dashed, ionic - long dashed, polar - dotted, Van der Waals - dash-dot).
The interactive features include filtering on interaction type, segments, residues and backbone or sidechain interactions.


Interaction cut-off:

Residue numbering:
H02G.S1D01G.s2s3R12H19Y23E24L25L26G.H5GproteinY-R-K6x32T6x36A6x33L-C3x55GPCRInteractions:AromaticHydrophobicIonicPolarVan der waalsG Protein segments:G.S1G.s2s3G.H5GPCR segments:ICL2TM3TM6

GPCR-G protein backbone (bb) or sidechain (sc):





Structures

Sequence Color

ACDEFGHIKLMNPQRSTVWY-_+van-der-waalshydrophobicionicaromaticpolar
null2x393x493x503x533x543x555x615x656x296x326x336x366x378x478x48G.H5.26G.H5.25G.H5.24G.H5.23G.H5.22G.H5.20G.H5.19G.H5.17G.H5.16G.H5.15G.H5.12G.H5.11G.H5.08G.S3.03G.S3.01G.s2s3.01G.S1.02G.hns1.02Res. Pos.OR51G2 (8UXV)- (8UXV)----------------MDRAICIVEKATCTKMDRAICIVEKATCTKLQYHQLLRLEFCIRHVFRD

, , , GPCR
Interaction cut-off: strict (stick), loose (line)

NGL is a WebGL based 3D viewer powered by MMTF.