Refined structure (8GDB) of Gs -
EP4 receptor
GPCR CLASS (FAMILY)
SPECIES
G PROTEIN FAMILY
DATE
3D VIEW
REFINED G PROTEIN RESIDUES
Residue sidechains - 176 from structure (44.7%), 218 from model (55.3%)
Segment | Seq.num. | AA | CGN# | Backbone from | Sidechain from |
---|---|---|---|---|---|
G.HN | 1 | M | G.HN.01 | AF2 | AF2 |
G.HN | 2 | G | G.HN.02 | AF2 | AF2 |
G.HN | 3 | C | G.HN.09 | AF2 | AF2 |
G.HN | 4 | L | G.HN.10 | AF2 | AF2 |
G.HN | 5 | G | G.HN.11 | AF2 | AF2 |
G.HN | 6 | N | G.HN.22 | AF2 | AF2 |
G.HN | 7 | S | G.HN.23 | AF2 | AF2 |
G.HN | 8 | K | G.HN.24 | AF2 | AF2 |
G.HN | 9 | T | G.HN.26 | AF2 | AF2 |
G.HN | 10 | E | G.HN.27 | Structure | AF2 |
G.HN | 11 | D | G.HN.28 | Structure | AF2 |
G.HN | 12 | Q | G.HN.29 | Structure | Structure |
G.HN | 13 | R | G.HN.30 | Structure | AF2 |
G.HN | 14 | N | G.HN.31 | Structure | Structure |
G.HN | 15 | E | G.HN.32 | Structure | Structure |
G.HN | 16 | E | G.HN.33 | Structure | Structure |
G.HN | 17 | K | G.HN.34 | Structure | AF2 |
G.HN | 18 | A | G.HN.35 | Structure | Structure |
G.HN | 19 | Q | G.HN.36 | Structure | Structure |
G.HN | 20 | R | G.HN.37 | Structure | Structure |
G.HN | 21 | E | G.HN.38 | Structure | AF2 |
G.HN | 22 | A | G.HN.39 | Structure | Structure |
G.HN | 23 | N | G.HN.40 | Structure | Structure |
G.HN | 24 | K | G.HN.41 | Structure | Structure |
G.HN | 25 | K | G.HN.42 | Structure | Structure |
G.HN | 26 | I | G.HN.43 | Structure | Structure |
G.HN | 27 | E | G.HN.44 | Structure | Structure |
G.HN | 28 | K | G.HN.45 | Structure | Structure |
G.HN | 29 | Q | G.HN.46 | Structure | Structure |
G.HN | 30 | L | G.HN.47 | Structure | Structure |
G.HN | 31 | Q | G.HN.48 | Structure | Structure |
G.HN | 32 | K | G.HN.49 | Structure | Structure |
G.HN | 33 | D | G.HN.50 | Structure | Structure |
G.HN | 34 | K | G.HN.51 | Structure | Structure |
G.HN | 35 | Q | G.HN.52 | Structure | Structure |
G.HN | 36 | V | G.HN.53 | Structure | Structure |
G.hns1 | 37 | Y | G.hns1.01 | Structure | Structure |
G.hns1 | 38 | R | G.hns1.02 | Structure | Structure |
G.hns1 | 39 | A | G.hns1.03 | Structure | Structure |
G.S1 | 40 | T | G.S1.01 | Structure | Structure |
G.S1 | 41 | H | G.S1.02 | Structure | Structure |
G.S1 | 42 | R | G.S1.03 | Structure | Structure |
G.S1 | 43 | L | G.S1.04 | Structure | Structure |
G.S1 | 44 | L | G.S1.05 | Structure | Structure |
G.S1 | 45 | L | G.S1.06 | Structure | Structure |
G.S1 | 46 | L | G.S1.07 | Structure | Structure |
G.s1h1 | 47 | G | G.s1h1.01 | Structure | Structure |
G.s1h1 | 48 | A | G.s1h1.02 | Structure | Structure |
G.s1h1 | 49 | G | G.s1h1.03 | Structure | Structure |
G.s1h1 | 50 | E | G.s1h1.04 | Structure | AF2 |
G.s1h1 | 51 | S | G.s1h1.05 | Structure | Structure |
G.s1h1 | 52 | G | G.s1h1.06 | Structure | Structure |
G.H1 | 53 | K | G.H1.01 | Structure | Structure |
G.H1 | 54 | S | G.H1.02 | Structure | AF2 |
G.H1 | 55 | T | G.H1.03 | Structure | Structure |
G.H1 | 56 | I | G.H1.04 | Structure | Structure |
G.H1 | 57 | V | G.H1.05 | Structure | Structure |
G.H1 | 58 | K | G.H1.06 | Structure | AF2 |
G.H1 | 59 | Q | G.H1.07 | Structure | AF2 |
G.H1 | 60 | M | G.H1.08 | AF2 | AF2 |
G.H1 | 61 | R | G.H1.09 | AF2 | AF2 |
G.H1 | 62 | I | G.H1.10 | AF2 | AF2 |
G.H1 | 63 | L | G.H1.11 | AF2 | AF2 |
G.H1 | 64 | H | G.H1.12 | AF2 | AF2 |
G.h1ha | 65 | V | G.h1ha.01 | AF2 | AF2 |
G.h1ha | 66 | N | G.h1ha.02 | AF2 | AF2 |
G.h1ha | 67 | G | G.h1ha.03 | AF2 | AF2 |
G.h1ha | 68 | F | G.h1ha.04 | AF2 | AF2 |
G.h1ha | 69 | N | G.h1ha.05 | AF2 | AF2 |
G.h1ha | 70 | G | G.h1ha.06 | AF2 | AF2 |
G.h1ha | 71 | E | G.h1ha.07 | AF2 | AF2 |
G.h1ha | 72 | G | G.h1ha.08 | AF2 | AF2 |
G.h1ha | 73 | G | G.h1ha.09 | AF2 | AF2 |
G.h1ha | 74 | E | G.h1ha.10 | AF2 | AF2 |
G.h1ha | 75 | E | G.h1ha.11 | AF2 | AF2 |
G.h1ha | 76 | D | G.h1ha.12 | AF2 | AF2 |
G.h1ha | 77 | P | G.h1ha.13 | AF2 | AF2 |
G.h1ha | 78 | Q | G.h1ha.14 | AF2 | AF2 |
G.h1ha | 79 | A | G.h1ha.15 | AF2 | AF2 |
G.h1ha | 80 | A | G.h1ha.16 | AF2 | AF2 |
G.h1ha | 81 | R | G.h1ha.17 | AF2 | AF2 |
G.h1ha | 82 | S | G.h1ha.18 | AF2 | AF2 |
G.h1ha | 83 | N | G.h1ha.19 | AF2 | AF2 |
G.h1ha | 84 | S | G.h1ha.20 | AF2 | AF2 |
H.HA | 85 | D | H.HA.01 | AF2 | AF2 |
H.HA | 86 | G | H.HA.02 | AF2 | AF2 |
H.HA | 87 | E | H.HA.03 | AF2 | AF2 |
H.HA | 88 | K | H.HA.04 | AF2 | AF2 |
H.HA | 89 | A | H.HA.05 | AF2 | AF2 |
H.HA | 90 | T | H.HA.06 | AF2 | AF2 |
H.HA | 91 | K | H.HA.07 | AF2 | AF2 |
H.HA | 92 | V | H.HA.08 | AF2 | AF2 |
H.HA | 93 | Q | H.HA.09 | AF2 | AF2 |
H.HA | 94 | D | H.HA.10 | AF2 | AF2 |
H.HA | 95 | I | H.HA.11 | AF2 | AF2 |
H.HA | 96 | K | H.HA.12 | AF2 | AF2 |
H.HA | 97 | N | H.HA.13 | AF2 | AF2 |
H.HA | 98 | N | H.HA.14 | AF2 | AF2 |
H.HA | 99 | L | H.HA.15 | AF2 | AF2 |
H.HA | 100 | K | H.HA.16 | AF2 | AF2 |
H.HA | 101 | E | H.HA.17 | AF2 | AF2 |
H.HA | 102 | A | H.HA.18 | AF2 | AF2 |
H.HA | 103 | I | H.HA.19 | AF2 | AF2 |
H.HA | 104 | E | H.HA.20 | AF2 | AF2 |
H.HA | 105 | T | H.HA.21 | AF2 | AF2 |
H.HA | 106 | I | H.HA.22 | AF2 | AF2 |
H.HA | 107 | V | H.HA.23 | AF2 | AF2 |
H.HA | 108 | A | H.HA.24 | AF2 | AF2 |
H.HA | 109 | A | H.HA.25 | AF2 | AF2 |
H.HA | 110 | M | H.HA.26 | AF2 | AF2 |
H.HA | 111 | S | H.HA.27 | AF2 | AF2 |
H.HA | 112 | N | H.HA.28 | AF2 | AF2 |
H.HA | 113 | L | H.HA.29 | AF2 | AF2 |
H.hahb | 114 | V | H.hahb.01 | AF2 | AF2 |
H.hahb | 115 | P | H.hahb.02 | AF2 | AF2 |
H.hahb | 116 | P | H.hahb.03 | AF2 | AF2 |
H.hahb | 117 | V | H.hahb.04 | AF2 | AF2 |
H.hahb | 118 | E | H.hahb.05 | AF2 | AF2 |
H.hahb | 119 | L | H.hahb.06 | AF2 | AF2 |
H.hahb | 120 | A | H.hahb.07 | AF2 | AF2 |
H.hahb | 121 | N | H.hahb.08 | AF2 | AF2 |
H.hahb | 122 | P | H.hahb.09 | AF2 | AF2 |
H.HB | 123 | E | H.HB.01 | AF2 | AF2 |
H.HB | 124 | N | H.HB.02 | AF2 | AF2 |
H.HB | 125 | Q | H.HB.03 | AF2 | AF2 |
H.HB | 126 | F | H.HB.04 | AF2 | AF2 |
H.HB | 127 | R | H.HB.05 | AF2 | AF2 |
H.HB | 128 | V | H.HB.06 | AF2 | AF2 |
H.HB | 129 | D | H.HB.07 | AF2 | AF2 |
H.HB | 130 | Y | H.HB.08 | AF2 | AF2 |
H.HB | 131 | I | H.HB.09 | AF2 | AF2 |
H.HB | 132 | L | H.HB.10 | AF2 | AF2 |
H.HB | 133 | S | H.HB.11 | AF2 | AF2 |
H.HB | 134 | V | H.HB.12 | AF2 | AF2 |
H.HB | 135 | M | H.HB.13 | AF2 | AF2 |
H.HB | 136 | N | H.HB.14 | AF2 | AF2 |
H.hbhc | 137 | V | H.hbhc.01 | AF2 | AF2 |
H.hbhc | 138 | P | H.hbhc.02 | AF2 | AF2 |
H.hbhc | 139 | D | H.hbhc.03 | AF2 | AF2 |
H.hbhc | 140 | F | H.hbhc.04 | AF2 | AF2 |
H.hbhc | 141 | D | H.hbhc.13 | AF2 | AF2 |
H.hbhc | 142 | F | H.hbhc.14 | AF2 | AF2 |
H.hbhc | 143 | P | H.hbhc.15 | AF2 | AF2 |
H.HC | 144 | P | H.HC.01 | AF2 | AF2 |
H.HC | 145 | E | H.HC.02 | AF2 | AF2 |
H.HC | 146 | F | H.HC.03 | AF2 | AF2 |
H.HC | 147 | Y | H.HC.04 | AF2 | AF2 |
H.HC | 148 | E | H.HC.05 | AF2 | AF2 |
H.HC | 149 | H | H.HC.06 | AF2 | AF2 |
H.HC | 150 | A | H.HC.07 | AF2 | AF2 |
H.HC | 151 | K | H.HC.08 | AF2 | AF2 |
H.HC | 152 | A | H.HC.09 | AF2 | AF2 |
H.HC | 153 | L | H.HC.10 | AF2 | AF2 |
H.HC | 154 | W | H.HC.11 | AF2 | AF2 |
H.HC | 155 | E | H.HC.12 | AF2 | AF2 |
H.hchd | 156 | D | H.hchd.01 | AF2 | AF2 |
H.HD | 157 | E | H.HD.01 | AF2 | AF2 |
H.HD | 158 | G | H.HD.02 | AF2 | AF2 |
H.HD | 159 | V | H.HD.03 | AF2 | AF2 |
H.HD | 160 | R | H.HD.04 | AF2 | AF2 |
H.HD | 161 | A | H.HD.05 | AF2 | AF2 |
H.HD | 162 | C | H.HD.06 | AF2 | AF2 |
H.HD | 163 | Y | H.HD.07 | AF2 | AF2 |
H.HD | 164 | E | H.HD.08 | AF2 | AF2 |
H.HD | 165 | R | H.HD.09 | AF2 | AF2 |
H.HD | 166 | S | H.HD.10 | AF2 | AF2 |
H.HD | 167 | N | H.HD.11 | AF2 | AF2 |
H.HD | 168 | E | H.HD.12 | AF2 | AF2 |
H.hdhe | 169 | Y | H.hdhe.01 | AF2 | AF2 |
H.hdhe | 170 | Q | H.hdhe.02 | AF2 | AF2 |
H.hdhe | 171 | L | H.hdhe.03 | AF2 | AF2 |
H.hdhe | 172 | I | H.hdhe.04 | AF2 | AF2 |
H.hdhe | 173 | D | H.hdhe.05 | AF2 | AF2 |
H.HE | 174 | C | H.HE.01 | AF2 | AF2 |
H.HE | 175 | A | H.HE.02 | AF2 | AF2 |
H.HE | 176 | Q | H.HE.03 | AF2 | AF2 |
H.HE | 177 | Y | H.HE.04 | AF2 | AF2 |
H.HE | 178 | F | H.HE.05 | AF2 | AF2 |
H.HE | 179 | L | H.HE.06 | AF2 | AF2 |
H.HE | 180 | D | H.HE.07 | AF2 | AF2 |
H.HE | 181 | K | H.HE.08 | AF2 | AF2 |
H.HE | 182 | I | H.HE.09 | AF2 | AF2 |
H.HE | 183 | D | H.HE.10 | AF2 | AF2 |
H.HE | 184 | V | H.HE.11 | AF2 | AF2 |
H.HE | 185 | I | H.HE.12 | AF2 | AF2 |
H.HE | 186 | K | H.HE.13 | AF2 | AF2 |
H.hehf | 187 | Q | H.hehf.01 | AF2 | AF2 |
H.hehf | 188 | A | H.hehf.02 | AF2 | AF2 |
H.hehf | 189 | D | H.hehf.03 | AF2 | AF2 |
H.hehf | 190 | Y | H.hehf.04 | AF2 | AF2 |
H.hehf | 191 | V | H.hehf.05 | AF2 | AF2 |
H.hehf | 192 | P | H.hehf.06 | AF2 | AF2 |
H.hehf | 193 | S | H.hehf.07 | AF2 | AF2 |
H.HF | 194 | D | H.HF.01 | AF2 | AF2 |
H.HF | 195 | Q | H.HF.02 | AF2 | AF2 |
H.HF | 196 | D | H.HF.03 | AF2 | AF2 |
H.HF | 197 | L | H.HF.04 | AF2 | AF2 |
H.HF | 198 | L | H.HF.05 | AF2 | AF2 |
H.HF | 199 | R | H.HF.06 | AF2 | AF2 |
G.hfs2 | 200 | C | G.hfs2.01 | AF2 | AF2 |
G.hfs2 | 201 | R | G.hfs2.02 | AF2 | AF2 |
G.hfs2 | 202 | V | G.hfs2.03 | AF2 | AF2 |
G.hfs2 | 203 | L | G.hfs2.04 | AF2 | AF2 |
G.hfs2 | 204 | T | G.hfs2.05 | AF2 | AF2 |
G.hfs2 | 205 | S | G.hfs2.06 | Structure | Structure |
G.hfs2 | 206 | G | G.hfs2.07 | Structure | Structure |
G.S2 | 207 | I | G.S2.01 | Structure | Structure |
G.S2 | 208 | F | G.S2.02 | Structure | Structure |
G.S2 | 209 | E | G.S2.03 | Structure | AF2 |
G.S2 | 210 | T | G.S2.04 | Structure | Structure |
G.S2 | 211 | K | G.S2.05 | Structure | Structure |
G.S2 | 212 | F | G.S2.06 | Structure | Structure |
G.S2 | 213 | Q | G.S2.07 | Structure | Structure |
G.S2 | 214 | V | G.S2.08 | Structure | Structure |
G.s2s3 | 215 | D | G.s2s3.01 | Structure | Structure |
G.s2s3 | 216 | K | G.s2s3.02 | Structure | AF2 |
G.S3 | 217 | V | G.S3.01 | Structure | Structure |
G.S3 | 218 | N | G.S3.02 | Structure | Structure |
G.S3 | 219 | F | G.S3.03 | Structure | Structure |
G.S3 | 220 | H | G.S3.04 | Structure | Structure |
G.S3 | 221 | M | G.S3.05 | Structure | Structure |
G.S3 | 222 | F | G.S3.06 | Structure | Structure |
G.S3 | 223 | D | G.S3.07 | Structure | Structure |
G.S3 | 224 | V | G.S3.08 | Structure | Structure |
G.s3h2 | 225 | G | G.s3h2.01 | Structure | Structure |
G.s3h2 | 226 | G | G.s3h2.02 | Structure | AF2 |
G.s3h2 | 227 | Q | G.s3h2.03 | Structure | Structure |
G.H2 | 228 | R | G.H2.01 | Structure | Structure |
G.H2 | 229 | D | G.H2.02 | Structure | AF2 |
G.H2 | 230 | E | G.H2.03 | Structure | Structure |
G.H2 | 231 | R | G.H2.04 | Structure | Structure |
G.H2 | 232 | R | G.H2.05 | Structure | Structure |
G.H2 | 233 | K | G.H2.06 | Structure | Structure |
G.H2 | 234 | W | G.H2.07 | Structure | Structure |
G.H2 | 235 | I | G.H2.08 | Structure | Structure |
G.H2 | 236 | Q | G.H2.09 | Structure | Structure |
G.H2 | 237 | C | G.H2.10 | Structure | Structure |
G.h2s4 | 238 | F | G.h2s4.01 | Structure | Structure |
G.h2s4 | 239 | N | G.h2s4.02 | Structure | Structure |
G.h2s4 | 240 | D | G.h2s4.03 | Structure | AF2 |
G.h2s4 | 241 | V | G.h2s4.04 | Structure | Structure |
G.h2s4 | 242 | T | G.h2s4.05 | Structure | Structure |
G.S4 | 243 | A | G.S4.01 | Structure | Structure |
G.S4 | 244 | I | G.S4.02 | Structure | Structure |
G.S4 | 245 | I | G.S4.03 | Structure | Structure |
G.S4 | 246 | F | G.S4.04 | Structure | Structure |
G.S4 | 247 | V | G.S4.05 | Structure | Structure |
G.S4 | 248 | V | G.S4.06 | Structure | Structure |
G.S4 | 249 | A | G.S4.07 | Structure | Structure |
G.s4h3 | 250 | S | G.s4h3.01 | Structure | AF2 |
G.s4h3 | 251 | S | G.s4h3.02 | Structure | AF2 |
G.s4h3 | 252 | S | G.s4h3.03 | Structure | AF2 |
G.s4h3 | 253 | Y | G.s4h3.04 | Structure | AF2 |
G.s4h3 | 254 | N | G.s4h3.05 | Structure | AF2 |
G.s4h3 | 255 | M | G.s4h3.06 | AF2 | AF2 |
G.s4h3 | 256 | V | G.s4h3.07 | AF2 | AF2 |
G.s4h3 | 257 | I | G.s4h3.08 | AF2 | AF2 |
G.s4h3 | 258 | R | G.s4h3.09 | AF2 | AF2 |
G.s4h3 | 259 | E | G.s4h3.10 | AF2 | AF2 |
G.s4h3 | 260 | D | G.s4h3.11 | AF2 | AF2 |
G.s4h3 | 261 | N | G.s4h3.12 | AF2 | AF2 |
G.s4h3 | 262 | Q | G.s4h3.13 | AF2 | AF2 |
G.s4h3 | 263 | T | G.s4h3.14 | AF2 | AF2 |
G.s4h3 | 264 | N | G.s4h3.15 | Structure | Structure |
G.H3 | 265 | R | G.H3.01 | Structure | AF2 |
G.H3 | 266 | L | G.H3.02 | Structure | Structure |
G.H3 | 267 | Q | G.H3.03 | Structure | Structure |
G.H3 | 268 | E | G.H3.04 | Structure | AF2 |
G.H3 | 269 | A | G.H3.05 | Structure | Structure |
G.H3 | 270 | L | G.H3.06 | Structure | Structure |
G.H3 | 271 | N | G.H3.07 | Structure | AF2 |
G.H3 | 272 | L | G.H3.08 | Structure | Structure |
G.H3 | 273 | F | G.H3.09 | Structure | Structure |
G.H3 | 274 | K | G.H3.10 | Structure | AF2 |
G.H3 | 275 | S | G.H3.11 | Structure | Structure |
G.H3 | 276 | I | G.H3.12 | Structure | Structure |
G.H3 | 277 | W | G.H3.13 | Structure | Structure |
G.H3 | 278 | N | G.H3.14 | Structure | Structure |
G.H3 | 279 | N | G.H3.15 | Structure | Structure |
G.H3 | 280 | R | G.H3.16 | Structure | AF2 |
G.H3 | 281 | W | G.H3.17 | Structure | Structure |
G.H3 | 282 | L | G.H3.18 | Structure | Structure |
G.h3s5 | 283 | R | G.h3s5.01 | Structure | AF2 |
G.h3s5 | 284 | T | G.h3s5.02 | Structure | AF2 |
G.h3s5 | 285 | I | G.h3s5.03 | Structure | AF2 |
G.S5 | 286 | S | G.S5.01 | Structure | Structure |
G.S5 | 287 | V | G.S5.02 | Structure | Structure |
G.S5 | 288 | I | G.S5.03 | Structure | Structure |
G.S5 | 289 | L | G.S5.04 | Structure | Structure |
G.S5 | 290 | F | G.S5.05 | Structure | Structure |
G.S5 | 291 | L | G.S5.06 | Structure | Structure |
G.S5 | 292 | N | G.S5.07 | Structure | Structure |
G.s5hg | 293 | K | G.s5hg.01 | Structure | Structure |
G.HG | 294 | Q | G.HG.01 | Structure | Structure |
G.HG | 295 | D | G.HG.02 | Structure | AF2 |
G.HG | 296 | L | G.HG.03 | Structure | Structure |
G.HG | 297 | L | G.HG.04 | Structure | Structure |
G.HG | 298 | A | G.HG.05 | Structure | Structure |
G.HG | 299 | E | G.HG.06 | Structure | Structure |
G.HG | 300 | K | G.HG.07 | Structure | Structure |
G.HG | 301 | V | G.HG.08 | Structure | AF2 |
G.HG | 302 | L | G.HG.09 | Structure | Structure |
G.HG | 303 | A | G.HG.10 | Structure | Structure |
G.HG | 304 | G | G.HG.11 | Structure | Structure |
G.HG | 305 | K | G.HG.12 | Structure | AF2 |
G.HG | 306 | S | G.HG.13 | Structure | AF2 |
G.HG | 307 | K | G.HG.14 | Structure | AF2 |
G.HG | 308 | I | G.HG.15 | Structure | Structure |
G.HG | 309 | E | G.HG.16 | Structure | AF2 |
G.HG | 310 | D | G.HG.17 | Structure | AF2 |
G.hgh4 | 311 | Y | G.hgh4.01 | Structure | AF2 |
G.hgh4 | 312 | F | G.hgh4.02 | Structure | Structure |
G.hgh4 | 313 | P | G.hgh4.03 | Structure | Structure |
G.hgh4 | 314 | E | G.hgh4.04 | Structure | AF2 |
G.hgh4 | 315 | F | G.hgh4.05 | Structure | Structure |
G.hgh4 | 316 | A | G.hgh4.06 | Structure | Structure |
G.hgh4 | 317 | R | G.hgh4.07 | Structure | AF2 |
G.hgh4 | 318 | Y | G.hgh4.08 | Structure | Structure |
G.hgh4 | 319 | T | G.hgh4.09 | Structure | Structure |
G.hgh4 | 320 | T | G.hgh4.10 | Structure | Structure |
G.hgh4 | 321 | P | G.hgh4.11 | Structure | Structure |
G.hgh4 | 322 | E | G.hgh4.12 | Structure | AF2 |
G.hgh4 | 323 | D | G.hgh4.13 | Structure | AF2 |
G.hgh4 | 324 | A | G.hgh4.14 | Structure | Structure |
G.hgh4 | 325 | T | G.hgh4.15 | Structure | AF2 |
G.hgh4 | 326 | P | G.hgh4.16 | Structure | Structure |
G.hgh4 | 327 | E | G.hgh4.17 | Structure | AF2 |
G.hgh4 | 328 | P | G.hgh4.18 | Structure | AF2 |
G.hgh4 | 329 | G | G.hgh4.19 | Structure | Structure |
G.hgh4 | 330 | E | G.hgh4.20 | Structure | AF2 |
G.hgh4 | 331 | D | G.hgh4.21 | Structure | AF2 |
G.H4 | 332 | P | G.H4.01 | Structure | Structure |
G.H4 | 333 | R | G.H4.02 | Structure | AF2 |
G.H4 | 334 | V | G.H4.03 | Structure | AF2 |
G.H4 | 335 | T | G.H4.04 | Structure | AF2 |
G.H4 | 336 | R | G.H4.05 | Structure | Structure |
G.H4 | 337 | A | G.H4.06 | Structure | Structure |
G.H4 | 338 | K | G.H4.07 | Structure | Structure |
G.H4 | 339 | Y | G.H4.08 | Structure | Structure |
G.H4 | 340 | F | G.H4.10 | Structure | Structure |
G.H4 | 341 | I | G.H4.11 | Structure | Structure |
G.H4 | 342 | R | G.H4.12 | Structure | Structure |
G.H4 | 343 | D | G.H4.13 | Structure | Structure |
G.H4 | 344 | E | G.H4.14 | Structure | Structure |
G.H4 | 345 | F | G.H4.15 | Structure | Structure |
G.H4 | 346 | L | G.H4.16 | Structure | Structure |
G.H4 | 347 | R | G.H4.17 | Structure | Structure |
G.h4s6 | 348 | I | G.h4s6.01 | Structure | Structure |
G.h4s6 | 349 | S | G.h4s6.02 | Structure | Structure |
G.h4s6 | 350 | T | G.h4s6.03 | Structure | Structure |
G.h4s6 | 351 | A | G.h4s6.04 | Structure | Structure |
G.h4s6 | 352 | S | G.h4s6.08 | Structure | AF2 |
G.h4s6 | 353 | G | G.h4s6.09 | Structure | Structure |
G.h4s6 | 354 | D | G.h4s6.10 | Structure | AF2 |
G.h4s6 | 355 | G | G.h4s6.11 | Structure | Structure |
G.h4s6 | 356 | R | G.h4s6.12 | Structure | AF2 |
G.h4s6 | 357 | H | G.h4s6.13 | Structure | Structure |
G.h4s6 | 358 | Y | G.h4s6.20 | Structure | Structure |
G.S6 | 359 | C | G.S6.01 | Structure | Structure |
G.S6 | 360 | Y | G.S6.02 | Structure | Structure |
G.S6 | 361 | P | G.S6.03 | Structure | AF2 |
G.S6 | 362 | H | G.S6.04 | Structure | Structure |
G.S6 | 363 | F | G.S6.05 | Structure | Structure |
G.s6h5 | 364 | T | G.s6h5.01 | Structure | Structure |
G.s6h5 | 365 | C | G.s6h5.02 | Structure | Structure |
G.s6h5 | 366 | A | G.s6h5.03 | Structure | Structure |
G.s6h5 | 367 | V | G.s6h5.04 | Structure | AF2 |
G.s6h5 | 368 | D | G.s6h5.05 | Structure | Structure |
G.H5 | 369 | T | G.H5.01 | Structure | AF2 |
G.H5 | 370 | E | G.H5.02 | Structure | AF2 |
G.H5 | 371 | N | G.H5.03 | Structure | Structure |
G.H5 | 372 | I | G.H5.04 | Structure | Structure |
G.H5 | 373 | R | G.H5.05 | Structure | Structure |
G.H5 | 374 | R | G.H5.06 | Structure | Structure |
G.H5 | 375 | V | G.H5.07 | Structure | Structure |
G.H5 | 376 | F | G.H5.08 | Structure | Structure |
G.H5 | 377 | N | G.H5.09 | Structure | Structure |
G.H5 | 378 | D | G.H5.10 | Structure | Structure |
G.H5 | 379 | C | G.H5.11 | Structure | Structure |
G.H5 | 380 | R | G.H5.12 | Structure | Structure |
G.H5 | 381 | D | G.H5.13 | Structure | Structure |
G.H5 | 382 | I | G.H5.14 | Structure | Structure |
G.H5 | 383 | I | G.H5.15 | Structure | Structure |
G.H5 | 384 | Q | G.H5.16 | Structure | Structure |
G.H5 | 385 | R | G.H5.17 | Structure | Structure |
G.H5 | 386 | M | G.H5.18 | Structure | Structure |
G.H5 | 387 | H | G.H5.19 | Structure | Structure |
G.H5 | 388 | L | G.H5.20 | Structure | Structure |
G.H5 | 389 | R | G.H5.21 | Structure | Structure |
G.H5 | 390 | Q | G.H5.22 | Structure | Structure |
G.H5 | 391 | Y | G.H5.23 | Structure | Structure |
G.H5 | 392 | E | G.H5.24 | Structure | Structure |
G.H5 | 393 | L | G.H5.25 | Structure | AF2 |
G.H5 | 394 | L | G.H5.26 | Structure | Structure |
REFINED GPCR RESIDUES
Residue sidechains - 245 from structure (74.0%), 86 from model (26.0%)
Segment | Seq.num. | AA | GPCRdb# | Backbone from | Sidechain from |
---|---|---|---|---|---|
N-term | 1 | M | - | AF2 | AF2 |
N-term | 2 | S | - | AF2 | AF2 |
N-term | 3 | T | - | AF2 | AF2 |
N-term | 4 | P | - | AF2 | AF2 |
N-term | 5 | G | - | AF2 | AF2 |
N-term | 6 | V | - | AF2 | AF2 |
N-term | 7 | N | - | AF2 | AF2 |
N-term | 8 | S | - | AF2 | AF2 |
N-term | 9 | S | - | AF2 | AF2 |
N-term | 10 | A | - | AF2 | AF2 |
N-term | 11 | S | - | AF2 | AF2 |
N-term | 12 | L | - | AF2 | AF2 |
N-term | 13 | S | - | AF2 | AF2 |
N-term | 14 | P | - | AF2 | AF2 |
N-term | 15 | D | - | AF2 | AF2 |
N-term | 16 | R | - | AF2 | AF2 |
N-term | 17 | L | - | AF2 | AF2 |
TM1 | 18 | N | 1.33x33 | AF2 | AF2 |
TM1 | 19 | S | 1.34x34 | Structure | Structure |
TM1 | 20 | P | 1.35x35 | Structure | Structure |
TM1 | 21 | V | 1.36x36 | Structure | Structure |
TM1 | 22 | T | 1.37x37 | Structure | AF2 |
TM1 | 23 | I | 1.38x38 | Structure | Structure |
TM1 | 24 | P | 1.39x39 | Structure | Structure |
TM1 | 25 | A | 1.40x40 | Structure | Structure |
TM1 | 26 | V | 1.41x41 | Structure | Structure |
TM1 | 27 | M | 1.42x42 | Structure | Structure |
TM1 | 28 | F | 1.43x43 | Structure | Structure |
TM1 | 29 | I | 1.44x44 | Structure | Structure |
TM1 | 30 | F | 1.45x45 | Structure | Structure |
TM1 | 31 | G | 1.46x46 | Structure | Structure |
TM1 | 32 | V | 1.47x47 | Structure | Structure |
TM1 | 33 | V | 1.48x48 | Structure | AF2 |
TM1 | 34 | G | 1.49x49 | Structure | Structure |
TM1 | 35 | N | 1.50x50 | Structure | Structure |
TM1 | 36 | L | 1.51x51 | Structure | Structure |
TM1 | 37 | V | 1.52x52 | Structure | Structure |
TM1 | 38 | A | 1.53x53 | Structure | Structure |
TM1 | 39 | I | 1.54x54 | Structure | Structure |
TM1 | 40 | V | 1.55x55 | Structure | Structure |
TM1 | 41 | V | 1.56x56 | Structure | Structure |
TM1 | 42 | L | 1.57x57 | Structure | Structure |
TM1 | 43 | C | 1.58x58 | Structure | Structure |
TM1 | 44 | K | 1.59x59 | Structure | AF2 |
TM1 | 45 | S | 1.60x60 | Structure | Structure |
ICL1 | 46 | R | - | Structure | AF2 |
ICL1 | 47 | K | - | Structure | AF2 |
ICL1 | 48 | E | - | Structure | AF2 |
ICL1 | 49 | Q | - | Structure | Structure |
ICL1 | 50 | K | - | Structure | Structure |
ICL1 | 51 | E | - | Structure | AF2 |
TM2 | 52 | T | 2.37x37 | Structure | Structure |
TM2 | 53 | T | 2.38x38 | Structure | Structure |
TM2 | 54 | F | 2.39x39 | Structure | Structure |
TM2 | 55 | Y | 2.40x40 | Structure | Structure |
TM2 | 56 | T | 2.41x41 | Structure | Structure |
TM2 | 57 | L | 2.42x42 | Structure | Structure |
TM2 | 58 | V | 2.43x43 | Structure | Structure |
TM2 | 59 | C | 2.44x44 | Structure | Structure |
TM2 | 60 | G | 2.45x45 | Structure | Structure |
TM2 | 61 | L | 2.46x46 | Structure | Structure |
TM2 | 62 | A | 2.47x47 | Structure | Structure |
TM2 | 63 | V | 2.48x48 | Structure | Structure |
TM2 | 64 | T | 2.49x49 | Structure | Structure |
TM2 | 65 | D | 2.50x50 | Structure | Structure |
TM2 | 66 | L | 2.51x51 | Structure | Structure |
TM2 | 67 | L | 2.52x52 | Structure | Structure |
TM2 | 68 | G | 2.53x53 | Structure | Structure |
TM2 | 69 | T | 2.54x54 | Structure | Structure |
TM2 | 70 | L | 2.55x55 | Structure | Structure |
TM2 | 71 | L | 2.56x56 | Structure | Structure |
TM2 | 72 | V | 2.57x57 | Structure | Structure |
TM2 | 73 | S | 2.58x58 | Structure | Structure |
TM2 | 74 | P | 2.59x59 | Structure | Structure |
TM2 | 75 | V | 2.60x60 | Structure | Structure |
TM2 | 76 | T | 2.61x61 | Structure | Structure |
TM2 | 77 | I | 2.62x62 | Structure | Structure |
TM2 | 78 | A | 2.63x63 | Structure | Structure |
TM2 | 79 | T | 2.64x64 | Structure | Structure |
TM2 | 80 | Y | 2.65x65 | Structure | Structure |
TM2 | 81 | M | 2.66x66 | Structure | Structure |
TM2 | 82 | K | 2.67x67 | Structure | AF2 |
ECL1 | 83 | G | - | Structure | Structure |
ECL1 | 84 | Q | 23.49x49 | Structure | Structure |
ECL1 | 85 | W | 23.50x50 | Structure | Structure |
ECL1 | 86 | P | 23.51x51 | Structure | Structure |
ECL1 | 87 | G | 23.52x52 | Structure | Structure |
TM3 | 88 | G | 3.21x21 | Structure | Structure |
TM3 | 89 | Q | 3.22x22 | Structure | AF2 |
TM3 | 90 | P | 3.23x23 | Structure | Structure |
TM3 | 91 | L | 3.24x24 | Structure | Structure |
TM3 | 92 | C | 3.25x25 | Structure | Structure |
TM3 | 93 | E | 3.26x26 | Structure | AF2 |
TM3 | 94 | Y | 3.27x27 | Structure | Structure |
TM3 | 95 | S | 3.28x28 | Structure | Structure |
TM3 | 96 | T | 3.29x29 | Structure | Structure |
TM3 | 97 | F | 3.30x30 | Structure | Structure |
TM3 | 98 | I | 3.31x31 | Structure | Structure |
TM3 | 99 | L | 3.32x32 | Structure | Structure |
TM3 | 100 | L | 3.33x33 | Structure | Structure |
TM3 | 101 | F | 3.34x34 | Structure | Structure |
TM3 | 102 | F | 3.35x35 | Structure | Structure |
TM3 | 103 | S | 3.36x36 | Structure | Structure |
TM3 | 104 | L | 3.37x37 | Structure | Structure |
TM3 | 105 | S | 3.38x38 | Structure | Structure |
TM3 | 106 | G | 3.39x39 | Structure | Structure |
TM3 | 107 | L | 3.40x40 | Structure | Structure |
TM3 | 108 | S | 3.41x41 | Structure | Structure |
TM3 | 109 | I | 3.42x42 | Structure | Structure |
TM3 | 110 | I | 3.43x43 | Structure | Structure |
TM3 | 111 | C | 3.44x44 | Structure | Structure |
TM3 | 112 | A | 3.45x45 | Structure | Structure |
TM3 | 113 | M | 3.46x46 | Structure | Structure |
TM3 | 114 | S | 3.47x47 | Structure | Structure |
TM3 | 115 | V | 3.48x48 | Structure | Structure |
TM3 | 116 | E | 3.49x49 | Structure | Structure |
TM3 | 117 | R | 3.50x50 | Structure | Structure |
TM3 | 118 | Y | 3.51x51 | Structure | Structure |
TM3 | 119 | L | 3.52x52 | Structure | Structure |
TM3 | 120 | A | 3.53x53 | Structure | Structure |
TM3 | 121 | I | 3.54x54 | Structure | Structure |
TM3 | 122 | N | 3.55x55 | Structure | Structure |
TM3 | 123 | H | 3.56x56 | Structure | Structure |
ICL2 | 124 | A | 34.50x50 | Structure | Structure |
ICL2 | 125 | Y | 34.51x51 | Structure | Structure |
ICL2 | 126 | F | 34.52x52 | Structure | Structure |
ICL2 | 127 | Y | 34.53x53 | Structure | Structure |
ICL2 | 128 | S | 34.54x54 | Structure | Structure |
ICL2 | 129 | H | 34.55x55 | Structure | Structure |
ICL2 | 130 | Y | 34.56x56 | Structure | Structure |
ICL2 | 131 | V | 34.57x57 | Structure | Structure |
TM4 | 132 | D | 4.38x38 | Structure | AF2 |
TM4 | 133 | K | 4.39x39 | Structure | AF2 |
TM4 | 134 | R | 4.40x40 | Structure | AF2 |
TM4 | 135 | L | 4.41x41 | Structure | Structure |
TM4 | 136 | A | 4.42x42 | Structure | Structure |
TM4 | 137 | G | 4.43x43 | Structure | Structure |
TM4 | 138 | L | 4.44x44 | Structure | Structure |
TM4 | 139 | T | 4.45x45 | Structure | Structure |
TM4 | 140 | L | 4.46x46 | Structure | Structure |
TM4 | 141 | F | 4.47x47 | Structure | Structure |
TM4 | 142 | A | 4.48x48 | Structure | Structure |
TM4 | 143 | V | 4.49x49 | Structure | Structure |
TM4 | 144 | Y | 4.50x50 | Structure | Structure |
TM4 | 145 | A | 4.51x51 | Structure | Structure |
TM4 | 146 | S | 4.52x52 | Structure | Structure |
TM4 | 147 | N | 4.53x53 | Structure | Structure |
TM4 | 148 | V | 4.54x54 | Structure | Structure |
TM4 | 149 | L | 4.55x55 | Structure | AF2 |
TM4 | 150 | F | 4.56x56 | Structure | Structure |
TM4 | 151 | C | 4.57x57 | Structure | Structure |
TM4 | 152 | A | 4.58x58 | Structure | Structure |
TM4 | 153 | L | 4.59x59 | Structure | AF2 |
TM4 | 154 | P | 4.60x60 | Structure | AF2 |
TM4 | 155 | N | 4.61x61 | Structure | AF2 |
TM4 | 156 | M | 4.62x62 | Structure | AF2 |
TM4 | 157 | G | 4.63x63 | Structure | Structure |
ECL2 | 158 | L | - | Structure | Structure |
ECL2 | 159 | G | - | Structure | Structure |
ECL2 | 160 | S | - | Structure | Structure |
ECL2 | 161 | S | - | Structure | Structure |
ECL2 | 162 | R | - | Structure | Structure |
ECL2 | 163 | L | - | Structure | AF2 |
ECL2 | 164 | Q | - | Structure | Structure |
ECL2 | 165 | Y | - | Structure | Structure |
ECL2 | 166 | P | - | Structure | Structure |
ECL2 | 167 | D | - | Structure | AF2 |
ECL2 | 168 | T | - | Structure | Structure |
ECL2 | 169 | W | - | Structure | Structure |
ECL2 | 170 | C | 45.50x50 | Structure | Structure |
ECL2 | 171 | F | 45.51x51 | Structure | Structure |
ECL2 | 172 | I | 45.52x52 | Structure | Structure |
ECL2 | 173 | D | - | Structure | AF2 |
ECL2 | 174 | W | - | Structure | Structure |
ECL2 | 175 | T | - | Structure | Structure |
ECL2 | 176 | T | - | Structure | Structure |
ECL2 | 177 | N | - | Structure | AF2 |
TM5 | 178 | V | 5.33x33 | Structure | Structure |
TM5 | 179 | T | 5.34x34 | Structure | AF2 |
TM5 | 180 | A | 5.35x35 | Structure | Structure |
TM5 | 181 | H | 5.36x36 | Structure | Structure |
TM5 | 182 | A | 5.37x37 | Structure | Structure |
TM5 | 183 | A | 5.38x38 | Structure | Structure |
TM5 | 184 | Y | 5.39x39 | Structure | Structure |
TM5 | 185 | S | 5.40x40 | Structure | Structure |
TM5 | 186 | Y | 5.41x41 | Structure | Structure |
TM5 | 187 | M | 5.42x42 | Structure | AF2 |
TM5 | 188 | Y | 5.43x43 | Structure | Structure |
TM5 | 189 | A | 5.44x44 | Structure | Structure |
TM5 | 190 | G | 5.45x45 | Structure | Structure |
TM5 | 191 | F | 5.46x46 | Structure | Structure |
TM5 | 192 | S | 5.47x47 | Structure | Structure |
TM5 | 193 | S | 5.48x48 | Structure | Structure |
TM5 | 194 | F | 5.49x49 | Structure | Structure |
TM5 | 195 | L | 5.50x50 | Structure | Structure |
TM5 | 196 | I | 5.51x51 | Structure | Structure |
TM5 | 197 | L | 5.52x52 | Structure | Structure |
TM5 | 198 | A | 5.53x53 | Structure | Structure |
TM5 | 199 | T | 5.54x54 | Structure | Structure |
TM5 | 200 | V | 5.55x55 | Structure | Structure |
TM5 | 201 | L | 5.56x56 | Structure | Structure |
TM5 | 202 | C | 5.57x57 | Structure | Structure |
TM5 | 203 | N | 5.58x58 | Structure | Structure |
TM5 | 204 | V | 5.59x59 | Structure | Structure |
TM5 | 205 | L | 5.60x60 | Structure | Structure |
TM5 | 206 | V | 5.61x61 | Structure | Structure |
TM5 | 207 | C | 5.62x62 | Structure | Structure |
TM5 | 208 | G | 5.63x63 | Structure | Structure |
TM5 | 209 | A | 5.64x64 | Structure | Structure |
TM5 | 210 | L | 5.65x65 | Structure | Structure |
TM5 | 211 | L | 5.66x66 | Structure | Structure |
TM5 | 212 | R | 5.67x67 | Structure | Structure |
TM5 | 213 | M | 5.68x68 | Structure | Structure |
TM5 | 214 | H | 5.69x69 | Structure | Structure |
TM5 | 215 | R | 5.70x70 | Structure | Structure |
TM5 | 216 | Q | 5.71x71 | Structure | Structure |
TM5 | 217 | F | 5.72x72 | Structure | Structure |
TM5 | 218 | M | 5.73x73 | Structure | Structure |
TM5 | 219 | R | 5.74x74 | Structure | Structure |
TM5 | 220 | R | 5.75x75 | Structure | Structure |
TM5 | 221 | T | 5.76x76 | Structure | AF2 |
ICL3 | 222 | S | - | AF2 | AF2 |
ICL3 | 223 | L | - | AF2 | AF2 |
ICL3 | 224 | G | - | AF2 | AF2 |
ICL3 | 225 | T | - | AF2 | AF2 |
ICL3 | 226 | E | - | AF2 | AF2 |
ICL3 | 227 | Q | - | AF2 | AF2 |
ICL3 | 228 | H | - | AF2 | AF2 |
ICL3 | 254 | F | - | AF2 | AF2 |
ICL3 | 255 | R | - | AF2 | AF2 |
ICL3 | 256 | R | - | AF2 | AF2 |
ICL3 | 257 | R | - | AF2 | AF2 |
ICL3 | 258 | R | - | AF2 | AF2 |
ICL3 | 259 | S | - | AF2 | AF2 |
ICL3 | 260 | F | - | AF2 | AF2 |
TM6 | 261 | R | 6.24x24 | AF2 | AF2 |
TM6 | 262 | R | 6.25x25 | AF2 | AF2 |
TM6 | 263 | I | 6.26x26 | AF2 | AF2 |
TM6 | 264 | A | 6.27x27 | AF2 | AF2 |
TM6 | 265 | G | 6.28x28 | Structure | Structure |
TM6 | 266 | A | 6.29x29 | Structure | Structure |
TM6 | 267 | E | 6.30x30 | Structure | Structure |
TM6 | 268 | I | 6.31x31 | Structure | Structure |
TM6 | 269 | Q | 6.32x32 | Structure | Structure |
TM6 | 270 | M | 6.33x33 | Structure | Structure |
TM6 | 271 | V | 6.34x34 | Structure | Structure |
TM6 | 272 | I | 6.35x35 | Structure | Structure |
TM6 | 273 | L | 6.36x36 | Structure | Structure |
TM6 | 274 | L | 6.37x37 | Structure | Structure |
TM6 | 275 | I | 6.38x38 | Structure | Structure |
TM6 | 276 | A | 6.39x39 | Structure | Structure |
TM6 | 277 | T | 6.40x40 | Structure | Structure |
TM6 | 278 | S | 6.41x41 | Structure | Structure |
TM6 | 279 | L | 6.42x42 | Structure | Structure |
TM6 | 280 | V | 6.43x43 | Structure | Structure |
TM6 | 281 | V | 6.44x44 | Structure | Structure |
TM6 | 282 | L | 6.45x45 | Structure | Structure |
TM6 | 283 | I | 6.46x46 | Structure | Structure |
TM6 | 284 | C | 6.47x47 | Structure | Structure |
TM6 | 285 | S | 6.48x48 | Structure | Structure |
TM6 | 286 | I | 6.49x49 | Structure | Structure |
TM6 | 287 | P | 6.50x50 | Structure | Structure |
TM6 | 288 | L | 6.51x51 | Structure | Structure |
TM6 | 289 | V | 6.52x52 | Structure | Structure |
TM6 | 290 | V | 6.53x53 | Structure | Structure |
TM6 | 291 | R | 6.54x54 | Structure | Structure |
TM6 | 292 | V | 6.55x55 | Structure | Structure |
TM6 | 293 | F | 6.56x56 | Structure | Structure |
TM6 | 294 | V | 6.57x57 | Structure | Structure |
TM6 | 295 | N | 6.58x58 | Structure | Structure |
TM6 | 296 | Q | 6.59x59 | Structure | Structure |
TM6 | 297 | L | 6.60x60 | Structure | Structure |
TM6 | 298 | Y | 6.61x61 | Structure | AF2 |
ECL3 | 299 | Q | - | Structure | AF2 |
ECL3 | 300 | P | - | Structure | AF2 |
ECL3 | 301 | S | - | Structure | Structure |
ECL3 | 302 | L | - | Structure | Structure |
ECL3 | 303 | E | - | Structure | AF2 |
ECL3 | 304 | R | - | Structure | Structure |
ECL3 | 305 | E | - | Structure | AF2 |
ECL3 | 306 | V | - | Structure | Structure |
ECL3 | 307 | S | - | Structure | Structure |
ECL3 | 308 | K | - | Structure | AF2 |
TM7 | 309 | N | 7.33x32 | Structure | Structure |
TM7 | 310 | P | 7.34x33 | Structure | Structure |
TM7 | 311 | D | 7.35x34 | Structure | Structure |
TM7 | 312 | L | 7.36x35 | Structure | Structure |
TM7 | 313 | Q | 7.37x36 | Structure | Structure |
TM7 | 314 | A | 7.38x37 | Structure | Structure |
TM7 | 315 | I | 7.39x38 | Structure | Structure |
TM7 | 316 | R | 7.40x39 | Structure | Structure |
TM7 | 317 | I | 7.41x40 | Structure | Structure |
TM7 | 318 | A | 7.42x41 | Structure | Structure |
TM7 | 319 | S | 7.43x42 | Structure | Structure |
TM7 | 320 | V | 7.44x43 | Structure | Structure |
TM7 | 321 | N | 7.45x45 | Structure | Structure |
TM7 | 322 | P | 7.46x46 | Structure | Structure |
TM7 | 323 | I | 7.47x47 | Structure | Structure |
TM7 | 324 | L | 7.48x48 | Structure | Structure |
TM7 | 325 | D | 7.49x49 | Structure | Structure |
TM7 | 326 | P | 7.50x50 | Structure | Structure |
TM7 | 327 | W | 7.51x51 | Structure | Structure |
TM7 | 328 | I | 7.52x52 | Structure | Structure |
TM7 | 329 | Y | 7.53x53 | Structure | Structure |
TM7 | 330 | I | 7.54x54 | Structure | Structure |
TM7 | 331 | L | 7.55x55 | Structure | Structure |
TM7 | 332 | L | 7.56x56 | Structure | Structure |
H8 | 333 | R | 8.47x47 | Structure | Structure |
H8 | 334 | K | 8.48x48 | Structure | AF2 |
H8 | 335 | T | 8.49x49 | Structure | Structure |
H8 | 336 | V | 8.50x50 | Structure | Structure |
H8 | 337 | L | 8.51x51 | Structure | AF2 |
H8 | 338 | S | 8.52x52 | Structure | Structure |
H8 | 339 | K | 8.53x53 | Structure | AF2 |
H8 | 340 | A | 8.54x54 | Structure | Structure |
H8 | 341 | I | 8.55x55 | Structure | AF2 |
H8 | 342 | E | 8.56x56 | Structure | AF2 |
H8 | 343 | K | 8.57x57 | Structure | AF2 |
H8 | 344 | I | 8.58x58 | Structure | AF2 |
H8 | 345 | K | 8.59x59 | AF2 | AF2 |
H8 | 346 | C | 8.60x60 | AF2 | AF2 |
C-term | 347 | L | - | AF2 | AF2 |
C-term | 348 | F | - | AF2 | AF2 |
C-term | 349 | C | - | AF2 | AF2 |
C-term | 350 | R | - | AF2 | AF2 |
C-term | 351 | I | - | AF2 | AF2 |
C-term | 352 | G | - | AF2 | AF2 |
C-term | 353 | G | - | AF2 | AF2 |
C-term | 354 | S | - | AF2 | AF2 |
C-term | 355 | R | - | AF2 | AF2 |
C-term | 356 | R | - | AF2 | AF2 |
GPCR - G protein interface interactions
The biflare plot is a modified version of a flareplot, where lines are drawn between an inner concentric circle
(Gα residues)
and an outer concentric circle (GPCR residues) depicting the interface interactions.
Different interaction types are shown with different line types (aromatic - solid,
hydrophobic - dashed,
ionic - long dashed, polar - dotted, Van der Waals - dash-dot).
The interactive features include filtering on interaction type, segments, residues and backbone or sidechain interactions.
GPCR-G protein backbone (bb) or sidechain (sc):
Structures
0 structures selected.
Sequence Color
Interaction frequency filter (%)
Gα,
Gβ,
Gγ,
GPCR
Interaction cut-off: strict (stick), loose (line)
Interaction type |
GPCR Segment |
AA |
Number |
Generic number |
Gα segment |
AA |
Number |
Generic number |
---|---|---|---|---|---|---|---|---|
Polar | TM5 | R | 220 | 5x75 | G.S6 | C | 359 | G.S6.01 |
Ionic | TM6 | E | 267 | 6x30 | G.H5 | R | 385 | G.H5.17 |
Polar | TM6 | E | 267 | 6x30 | G.H5 | R | 385 | G.H5.17 |
Van-der-waals | TM6 | E | 267 | 6x30 | G.H5 | R | 385 | G.H5.17 |
Polar | ICL3 | S | 222 | - | G.hgh4 | D | 323 | G.hgh4.13 |
Hydrophobic | ICL3 | S | 222 | - | G.hgh4 | D | 323 | G.hgh4.13 |
Van-der-waals | ICL3 | S | 222 | - | G.hgh4 | D | 323 | G.hgh4.13 |
Hydrophobic | TM4 | D | 132 | 4x38 | G.hns1 | R | 38 | G.hns1.02 |
Hydrophobic | ICL2 | A | 124 | 34x50 | G.H5 | R | 380 | G.H5.12 |
Polar | TM3 | E | 116 | 3x49 | G.H5 | Q | 390 | G.H5.22 |
Aromatic | TM5 | F | 217 | 5x72 | G.H5 | R | 385 | G.H5.17 |
Hydrophobic | TM5 | F | 217 | 5x72 | G.H5 | R | 385 | G.H5.17 |
Van-der-waals | TM5 | F | 217 | 5x72 | G.H5 | R | 385 | G.H5.17 |
Hydrophobic | TM6 | M | 270 | 6x33 | G.H5 | Y | 391 | G.H5.23 |
Aromatic | ICL2 | Y | 125 | 34x51 | G.S1 | H | 41 | G.S1.02 |
Hydrophobic | ICL2 | Y | 125 | 34x51 | G.S1 | H | 41 | G.S1.02 |
Hydrophobic | H8 | V | 336 | 8x50 | G.H5 | L | 394 | G.H5.26 |
Van-der-waals | H8 | V | 336 | 8x50 | G.H5 | L | 394 | G.H5.26 |
Hydrophobic | ICL2 | A | 124 | 34x50 | G.H5 | H | 387 | G.H5.19 |
Van-der-waals | ICL2 | A | 124 | 34x50 | G.H5 | H | 387 | G.H5.19 |
Hydrophobic | ICL2 | Y | 125 | 34x51 | G.S3 | F | 219 | G.S3.03 |
Aromatic | TM5 | R | 220 | 5x75 | G.S6 | Y | 360 | G.S6.02 |
Hydrophobic | TM5 | R | 220 | 5x75 | G.S6 | Y | 360 | G.S6.02 |
Van-der-waals | TM5 | R | 220 | 5x75 | G.S6 | Y | 360 | G.S6.02 |
Van-der-waals | ICL3 | T | 225 | - | G.hgh4 | Y | 318 | G.hgh4.08 |
Polar | ICL1 | Q | 49 | - | G.H5 | L | 393 | G.H5.25 |
Hydrophobic | ICL1 | Q | 49 | - | G.H5 | L | 393 | G.H5.25 |
Van-der-waals | ICL1 | Q | 49 | - | G.H5 | L | 393 | G.H5.25 |
Polar | TM3 | A | 120 | 3x53 | G.H5 | H | 387 | G.H5.19 |
Hydrophobic | TM3 | A | 120 | 3x53 | G.H5 | H | 387 | G.H5.19 |
Van-der-waals | TM3 | A | 120 | 3x53 | G.H5 | H | 387 | G.H5.19 |
Aromatic | TM2 | F | 54 | 2x39 | G.H5 | Y | 391 | G.H5.23 |
Hydrophobic | TM2 | F | 54 | 2x39 | G.H5 | Y | 391 | G.H5.23 |
Polar | TM6 | Q | 269 | 6x32 | G.H5 | E | 392 | G.H5.24 |
Van-der-waals | TM6 | Q | 269 | 6x32 | G.H5 | E | 392 | G.H5.24 |
Hydrophobic | ICL3 | F | 260 | - | G.h4s6 | T | 350 | G.h4s6.03 |
Van-der-waals | ICL3 | F | 260 | - | G.h4s6 | T | 350 | G.h4s6.03 |
Polar | TM5 | M | 213 | 5x68 | G.H5 | R | 385 | G.H5.17 |
Hydrophobic | TM5 | M | 213 | 5x68 | G.H5 | R | 385 | G.H5.17 |
Polar | ICL2 | V | 131 | 34x57 | G.hns1 | R | 38 | G.hns1.02 |
Van-der-waals | ICL2 | V | 131 | 34x57 | G.hns1 | R | 38 | G.hns1.02 |
Hydrophobic | TM5 | M | 213 | 5x68 | G.H5 | L | 388 | G.H5.20 |
Hydrophobic | H8 | R | 333 | 8x47 | G.H5 | E | 392 | G.H5.24 |
Hydrophobic | TM2 | Y | 55 | 2x40 | G.H5 | L | 394 | G.H5.26 |
Polar | ICL3 | G | 224 | - | G.H4 | D | 343 | G.H4.13 |
Hydrophobic | ICL2 | S | 128 | 34x54 | G.H5 | H | 387 | G.H5.19 |
Hydrophobic | TM2 | T | 52 | 2x37 | G.H5 | L | 393 | G.H5.25 |
Polar | TM2 | T | 52 | 2x37 | G.H5 | Q | 390 | G.H5.22 |
Hydrophobic | TM2 | T | 52 | 2x37 | G.H5 | Q | 390 | G.H5.22 |
Van-der-waals | TM2 | T | 52 | 2x37 | G.H5 | Q | 390 | G.H5.22 |
Hydrophobic | TM2 | F | 54 | 2x39 | G.H5 | L | 394 | G.H5.26 |
Van-der-waals | TM2 | F | 54 | 2x39 | G.H5 | L | 394 | G.H5.26 |
Hydrophobic | TM5 | L | 210 | 5x65 | G.H5 | L | 388 | G.H5.20 |
Polar | ICL2 | H | 129 | 34x55 | G.hns1 | A | 39 | G.hns1.03 |
Hydrophobic | ICL2 | H | 129 | 34x55 | G.hns1 | A | 39 | G.hns1.03 |
Polar | ICL2 | H | 129 | 34x55 | G.S1 | H | 41 | G.S1.02 |
Aromatic | ICL2 | H | 129 | 34x55 | G.S1 | H | 41 | G.S1.02 |
Hydrophobic | ICL2 | H | 129 | 34x55 | G.S1 | H | 41 | G.S1.02 |
Van-der-waals | ICL2 | H | 129 | 34x55 | G.S1 | H | 41 | G.S1.02 |
Hydrophobic | TM6 | M | 270 | 6x33 | G.H5 | L | 388 | G.H5.20 |
Hydrophobic | TM6 | I | 263 | 6x26 | G.h4s6 | G | 355 | G.h4s6.11 |
Hydrophobic | TM3 | A | 120 | 3x53 | G.H5 | Y | 391 | G.H5.23 |
Van-der-waals | TM3 | A | 120 | 3x53 | G.H5 | Y | 391 | G.H5.23 |
Hydrophobic | TM5 | F | 217 | 5x72 | G.h4s6 | Y | 358 | G.h4s6.20 |
Polar | TM3 | R | 117 | 3x50 | G.H5 | Y | 391 | G.H5.23 |
Aromatic | TM3 | R | 117 | 3x50 | G.H5 | Y | 391 | G.H5.23 |
Hydrophobic | TM3 | R | 117 | 3x50 | G.H5 | Y | 391 | G.H5.23 |
Van-der-waals | TM3 | R | 117 | 3x50 | G.H5 | Y | 391 | G.H5.23 |
Hydrophobic | ICL3 | L | 223 | - | G.H4 | D | 343 | G.H4.13 |
Polar | ICL2 | Y | 125 | 34x51 | G.H5 | R | 380 | G.H5.12 |
Hydrophobic | ICL2 | Y | 125 | 34x51 | G.H5 | R | 380 | G.H5.12 |
Van-der-waals | ICL2 | Y | 125 | 34x51 | G.H5 | R | 380 | G.H5.12 |
Hydrophobic | ICL3 | G | 224 | - | G.hgh4 | P | 321 | G.hgh4.11 |
Van-der-waals | ICL3 | G | 224 | - | G.hgh4 | P | 321 | G.hgh4.11 |
Aromatic | ICL2 | Y | 127 | 34x53 | G.H5 | H | 387 | G.H5.19 |
Hydrophobic | ICL2 | Y | 127 | 34x53 | G.H5 | H | 387 | G.H5.19 |
Van-der-waals | ICL2 | Y | 127 | 34x53 | G.H5 | H | 387 | G.H5.19 |
Hydrophobic | TM6 | I | 263 | 6x26 | G.h4s6 | D | 354 | G.h4s6.10 |
Ionic | TM5 | R | 220 | 5x75 | G.H5 | D | 381 | G.H5.13 |
Polar | TM3 | I | 121 | 3x54 | G.H5 | Q | 384 | G.H5.16 |
Van-der-waals | TM3 | I | 121 | 3x54 | G.H5 | Q | 384 | G.H5.16 |
Hydrophobic | ICL3 | L | 223 | - | G.H4 | L | 346 | G.H4.16 |
Hydrophobic | TM5 | M | 213 | 5x68 | G.H5 | Q | 384 | G.H5.16 |
Van-der-waals | TM5 | M | 213 | 5x68 | G.H5 | Q | 384 | G.H5.16 |
Polar | TM3 | E | 116 | 3x49 | G.H5 | Y | 391 | G.H5.23 |
Hydrophobic | TM3 | E | 116 | 3x49 | G.H5 | Y | 391 | G.H5.23 |
Van-der-waals | TM3 | E | 116 | 3x49 | G.H5 | Y | 391 | G.H5.23 |
Hydrophobic | ICL2 | Y | 125 | 34x51 | G.H5 | I | 383 | G.H5.15 |
Van-der-waals | ICL2 | Y | 125 | 34x51 | G.H5 | I | 383 | G.H5.15 |
Hydrophobic | ICL3 | L | 223 | - | G.hgh4 | P | 321 | G.hgh4.11 |
Hydrophobic | ICL2 | Y | 125 | 34x51 | G.S3 | V | 217 | G.S3.01 |
Hydrophobic | ICL2 | A | 124 | 34x50 | G.H5 | Q | 384 | G.H5.16 |
Polar | ICL2 | Y | 125 | 34x51 | G.H5 | F | 376 | G.H5.08 |
Aromatic | ICL2 | Y | 125 | 34x51 | G.H5 | F | 376 | G.H5.08 |
Hydrophobic | ICL2 | Y | 125 | 34x51 | G.H5 | F | 376 | G.H5.08 |
Van-der-waals | ICL2 | Y | 125 | 34x51 | G.H5 | F | 376 | G.H5.08 |
Polar | ICL3 | S | 222 | - | G.H4 | R | 342 | G.H4.12 |
Van-der-waals | ICL3 | S | 222 | - | G.H4 | R | 342 | G.H4.12 |
Polar | ICL2 | H | 129 | 34x55 | G.hns1 | R | 38 | G.hns1.02 |
Hydrophobic | ICL2 | S | 128 | 34x54 | G.H5 | I | 383 | G.H5.15 |
Hydrophobic | TM1 | L | 42 | 1x57 | G.H5 | L | 394 | G.H5.26 |
Van-der-waals | TM1 | L | 42 | 1x57 | G.H5 | L | 394 | G.H5.26 |
Hydrophobic | TM6 | I | 263 | 6x26 | G.h4s6 | Y | 358 | G.h4s6.20 |
Hydrophobic | TM3 | I | 121 | 3x54 | G.H5 | L | 388 | G.H5.20 |
Polar | H8 | T | 335 | 8x49 | G.H5 | E | 392 | G.H5.24 |
Polar | ICL2 | Y | 127 | 34x53 | G.H5 | Q | 390 | G.H5.22 |
Van-der-waals | ICL2 | Y | 127 | 34x53 | G.H5 | Q | 390 | G.H5.22 |
Hydrophobic | ICL2 | H | 129 | 34x55 | G.S3 | V | 217 | G.S3.01 |
Hydrophobic | ICL2 | A | 124 | 34x50 | G.H5 | I | 383 | G.H5.15 |