Refined structure (8POK) of Gs - H2 receptor

GPCR CLASS (FAMILY)

A (Rhodopsin)

SPECIES

Homo sapiens

G PROTEIN FAMILY

Gs

DATE

2024-11-26

3D VIEW

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Structure
GPCR
Gα
Gβ
Gγ
Model
AlphaFold2-Multimer

REFINED G PROTEIN RESIDUES

Residue backbones - 219 from structure (55.6%), 175 from model (44.4%)
Residue sidechains - 219 from structure (55.6%), 175 from model (44.4%)
Segment Seq.num. AA CGN# Backbone from Sidechain from
G.HN 1 M G.HN.01 AF2 AF2
G.HN 2 G G.HN.02 AF2 AF2
G.HN 3 C G.HN.09 AF2 AF2
G.HN 4 L G.HN.10 AF2 AF2
G.HN 5 G G.HN.11 AF2 AF2
G.HN 6 N G.HN.22 AF2 AF2
G.HN 7 S G.HN.23 AF2 AF2
G.HN 8 K G.HN.24 Structure Structure
G.HN 9 T G.HN.26 Structure Structure
G.HN 10 E G.HN.27 Structure Structure
G.HN 11 D G.HN.28 Structure Structure
G.HN 12 Q G.HN.29 Structure Structure
G.HN 13 R G.HN.30 Structure Structure
G.HN 14 N G.HN.31 Structure Structure
G.HN 15 E G.HN.32 Structure Structure
G.HN 16 E G.HN.33 Structure Structure
G.HN 17 K G.HN.34 Structure Structure
G.HN 18 A G.HN.35 Structure Structure
G.HN 19 Q G.HN.36 Structure Structure
G.HN 20 R G.HN.37 Structure Structure
G.HN 21 E G.HN.38 Structure Structure
G.HN 22 A G.HN.39 Structure Structure
G.HN 23 N G.HN.40 Structure Structure
G.HN 24 K G.HN.41 Structure Structure
G.HN 25 K G.HN.42 Structure Structure
G.HN 26 I G.HN.43 Structure Structure
G.HN 27 E G.HN.44 Structure Structure
G.HN 28 K G.HN.45 Structure Structure
G.HN 29 Q G.HN.46 Structure Structure
G.HN 30 L G.HN.47 Structure Structure
G.HN 31 Q G.HN.48 Structure Structure
G.HN 32 K G.HN.49 Structure Structure
G.HN 33 D G.HN.50 Structure Structure
G.HN 34 K G.HN.51 Structure Structure
G.HN 35 Q G.HN.52 Structure Structure
G.HN 36 V G.HN.53 Structure Structure
G.hns1 37 Y G.hns1.01 Structure Structure
G.hns1 38 R G.hns1.02 Structure Structure
G.hns1 39 A G.hns1.03 Structure Structure
G.S1 40 T G.S1.01 Structure Structure
G.S1 41 H G.S1.02 Structure Structure
G.S1 42 R G.S1.03 Structure Structure
G.S1 43 L G.S1.04 Structure Structure
G.S1 44 L G.S1.05 Structure Structure
G.S1 45 L G.S1.06 Structure Structure
G.S1 46 L G.S1.07 Structure Structure
G.s1h1 47 G G.s1h1.01 Structure Structure
G.s1h1 48 A G.s1h1.02 Structure Structure
G.s1h1 49 G G.s1h1.03 Structure Structure
G.s1h1 50 E G.s1h1.04 AF2 AF2
G.s1h1 51 S G.s1h1.05 AF2 AF2
G.s1h1 52 G G.s1h1.06 AF2 AF2
G.H1 53 K G.H1.01 AF2 AF2
G.H1 54 S G.H1.02 AF2 AF2
G.H1 55 T G.H1.03 AF2 AF2
G.H1 56 I G.H1.04 AF2 AF2
G.H1 57 V G.H1.05 AF2 AF2
G.H1 58 K G.H1.06 AF2 AF2
G.H1 59 Q G.H1.07 AF2 AF2
G.H1 60 M G.H1.08 AF2 AF2
G.H1 61 R G.H1.09 AF2 AF2
G.H1 62 I G.H1.10 AF2 AF2
G.H1 63 L G.H1.11 AF2 AF2
G.H1 64 H G.H1.12 AF2 AF2
G.h1ha 65 V G.h1ha.01 AF2 AF2
G.h1ha 66 N G.h1ha.02 AF2 AF2
G.h1ha 67 G G.h1ha.03 AF2 AF2
G.h1ha 68 F G.h1ha.04 AF2 AF2
G.h1ha 69 N G.h1ha.05 AF2 AF2
G.h1ha 70 G G.h1ha.06 AF2 AF2
G.h1ha 71 E G.h1ha.07 AF2 AF2
G.h1ha 72 G G.h1ha.08 AF2 AF2
G.h1ha 73 G G.h1ha.09 AF2 AF2
G.h1ha 74 E G.h1ha.10 AF2 AF2
G.h1ha 75 E G.h1ha.11 AF2 AF2
G.h1ha 76 D G.h1ha.12 AF2 AF2
G.h1ha 77 P G.h1ha.13 AF2 AF2
G.h1ha 78 Q G.h1ha.14 AF2 AF2
G.h1ha 79 A G.h1ha.15 AF2 AF2
G.h1ha 80 A G.h1ha.16 AF2 AF2
G.h1ha 81 R G.h1ha.17 AF2 AF2
G.h1ha 82 S G.h1ha.18 AF2 AF2
G.h1ha 83 N G.h1ha.19 AF2 AF2
G.h1ha 84 S G.h1ha.20 AF2 AF2
H.HA 85 D H.HA.01 AF2 AF2
H.HA 86 G H.HA.02 AF2 AF2
H.HA 87 E H.HA.03 AF2 AF2
H.HA 88 K H.HA.04 AF2 AF2
H.HA 89 A H.HA.05 AF2 AF2
H.HA 90 T H.HA.06 AF2 AF2
H.HA 91 K H.HA.07 AF2 AF2
H.HA 92 V H.HA.08 AF2 AF2
H.HA 93 Q H.HA.09 AF2 AF2
H.HA 94 D H.HA.10 AF2 AF2
H.HA 95 I H.HA.11 AF2 AF2
H.HA 96 K H.HA.12 AF2 AF2
H.HA 97 N H.HA.13 AF2 AF2
H.HA 98 N H.HA.14 AF2 AF2
H.HA 99 L H.HA.15 AF2 AF2
H.HA 100 K H.HA.16 AF2 AF2
H.HA 101 E H.HA.17 AF2 AF2
H.HA 102 A H.HA.18 AF2 AF2
H.HA 103 I H.HA.19 AF2 AF2
H.HA 104 E H.HA.20 AF2 AF2
H.HA 105 T H.HA.21 AF2 AF2
H.HA 106 I H.HA.22 AF2 AF2
H.HA 107 V H.HA.23 AF2 AF2
H.HA 108 A H.HA.24 AF2 AF2
H.HA 109 A H.HA.25 AF2 AF2
H.HA 110 M H.HA.26 AF2 AF2
H.HA 111 S H.HA.27 AF2 AF2
H.HA 112 N H.HA.28 AF2 AF2
H.HA 113 L H.HA.29 AF2 AF2
H.hahb 114 V H.hahb.01 AF2 AF2
H.hahb 115 P H.hahb.02 AF2 AF2
H.hahb 116 P H.hahb.03 AF2 AF2
H.hahb 117 V H.hahb.04 AF2 AF2
H.hahb 118 E H.hahb.05 AF2 AF2
H.hahb 119 L H.hahb.06 AF2 AF2
H.hahb 120 A H.hahb.07 AF2 AF2
H.hahb 121 N H.hahb.08 AF2 AF2
H.hahb 122 P H.hahb.09 AF2 AF2
H.HB 123 E H.HB.01 AF2 AF2
H.HB 124 N H.HB.02 AF2 AF2
H.HB 125 Q H.HB.03 AF2 AF2
H.HB 126 F H.HB.04 AF2 AF2
H.HB 127 R H.HB.05 AF2 AF2
H.HB 128 V H.HB.06 AF2 AF2
H.HB 129 D H.HB.07 AF2 AF2
H.HB 130 Y H.HB.08 AF2 AF2
H.HB 131 I H.HB.09 AF2 AF2
H.HB 132 L H.HB.10 AF2 AF2
H.HB 133 S H.HB.11 AF2 AF2
H.HB 134 V H.HB.12 AF2 AF2
H.HB 135 M H.HB.13 AF2 AF2
H.HB 136 N H.HB.14 AF2 AF2
H.hbhc 137 V H.hbhc.01 AF2 AF2
H.hbhc 138 P H.hbhc.02 AF2 AF2
H.hbhc 139 D H.hbhc.03 AF2 AF2
H.hbhc 140 F H.hbhc.04 AF2 AF2
H.hbhc 141 D H.hbhc.13 AF2 AF2
H.hbhc 142 F H.hbhc.14 AF2 AF2
H.hbhc 143 P H.hbhc.15 AF2 AF2
H.HC 144 P H.HC.01 AF2 AF2
H.HC 145 E H.HC.02 AF2 AF2
H.HC 146 F H.HC.03 AF2 AF2
H.HC 147 Y H.HC.04 AF2 AF2
H.HC 148 E H.HC.05 AF2 AF2
H.HC 149 H H.HC.06 AF2 AF2
H.HC 150 A H.HC.07 AF2 AF2
H.HC 151 K H.HC.08 AF2 AF2
H.HC 152 A H.HC.09 AF2 AF2
H.HC 153 L H.HC.10 AF2 AF2
H.HC 154 W H.HC.11 AF2 AF2
H.HC 155 E H.HC.12 AF2 AF2
H.hchd 156 D H.hchd.01 AF2 AF2
H.HD 157 E H.HD.01 AF2 AF2
H.HD 158 G H.HD.02 AF2 AF2
H.HD 159 V H.HD.03 AF2 AF2
H.HD 160 R H.HD.04 AF2 AF2
H.HD 161 A H.HD.05 AF2 AF2
H.HD 162 C H.HD.06 AF2 AF2
H.HD 163 Y H.HD.07 AF2 AF2
H.HD 164 E H.HD.08 AF2 AF2
H.HD 165 R H.HD.09 AF2 AF2
H.HD 166 S H.HD.10 AF2 AF2
H.HD 167 N H.HD.11 AF2 AF2
H.HD 168 E H.HD.12 AF2 AF2
H.hdhe 169 Y H.hdhe.01 AF2 AF2
H.hdhe 170 Q H.hdhe.02 AF2 AF2
H.hdhe 171 L H.hdhe.03 AF2 AF2
H.hdhe 172 I H.hdhe.04 AF2 AF2
H.hdhe 173 D H.hdhe.05 AF2 AF2
H.HE 174 C H.HE.01 AF2 AF2
H.HE 175 A H.HE.02 AF2 AF2
H.HE 176 Q H.HE.03 AF2 AF2
H.HE 177 Y H.HE.04 AF2 AF2
H.HE 178 F H.HE.05 AF2 AF2
H.HE 179 L H.HE.06 AF2 AF2
H.HE 180 D H.HE.07 AF2 AF2
H.HE 181 K H.HE.08 AF2 AF2
H.HE 182 I H.HE.09 AF2 AF2
H.HE 183 D H.HE.10 AF2 AF2
H.HE 184 V H.HE.11 AF2 AF2
H.HE 185 I H.HE.12 AF2 AF2
H.HE 186 K H.HE.13 AF2 AF2
H.hehf 187 Q H.hehf.01 AF2 AF2
H.hehf 188 A H.hehf.02 AF2 AF2
H.hehf 189 D H.hehf.03 AF2 AF2
H.hehf 190 Y H.hehf.04 AF2 AF2
H.hehf 191 V H.hehf.05 AF2 AF2
H.hehf 192 P H.hehf.06 AF2 AF2
H.hehf 193 S H.hehf.07 AF2 AF2
H.HF 194 D H.HF.01 AF2 AF2
H.HF 195 Q H.HF.02 AF2 AF2
H.HF 196 D H.HF.03 AF2 AF2
H.HF 197 L H.HF.04 AF2 AF2
H.HF 198 L H.HF.05 AF2 AF2
H.HF 199 R H.HF.06 AF2 AF2
G.hfs2 200 C G.hfs2.01 AF2 AF2
G.hfs2 201 R G.hfs2.02 AF2 AF2
G.hfs2 202 V G.hfs2.03 AF2 AF2
G.hfs2 203 L G.hfs2.04 AF2 AF2
G.hfs2 204 T G.hfs2.05 AF2 AF2
G.hfs2 205 S G.hfs2.06 AF2 AF2
G.hfs2 206 G G.hfs2.07 Structure Structure
G.S2 207 I G.S2.01 Structure Structure
G.S2 208 F G.S2.02 Structure Structure
G.S2 209 E G.S2.03 Structure Structure
G.S2 210 T G.S2.04 Structure Structure
G.S2 211 K G.S2.05 Structure Structure
G.S2 212 F G.S2.06 Structure Structure
G.S2 213 Q G.S2.07 Structure Structure
G.S2 214 V G.S2.08 Structure Structure
G.s2s3 215 D G.s2s3.01 Structure Structure
G.s2s3 216 K G.s2s3.02 Structure Structure
G.S3 217 V G.S3.01 Structure Structure
G.S3 218 N G.S3.02 Structure Structure
G.S3 219 F G.S3.03 Structure Structure
G.S3 220 H G.S3.04 Structure Structure
G.S3 221 M G.S3.05 Structure Structure
G.S3 222 F G.S3.06 Structure Structure
G.S3 223 D G.S3.07 Structure Structure
G.S3 224 V G.S3.08 Structure Structure
G.s3h2 225 G G.s3h2.01 Structure Structure
G.s3h2 226 G G.s3h2.02 Structure Structure
G.s3h2 227 Q G.s3h2.03 Structure Structure
G.H2 228 R G.H2.01 Structure Structure
G.H2 229 D G.H2.02 Structure Structure
G.H2 230 E G.H2.03 Structure Structure
G.H2 231 R G.H2.04 Structure Structure
G.H2 232 R G.H2.05 Structure Structure
G.H2 233 K G.H2.06 Structure Structure
G.H2 234 W G.H2.07 Structure Structure
G.H2 235 I G.H2.08 Structure Structure
G.H2 236 Q G.H2.09 Structure Structure
G.H2 237 C G.H2.10 Structure Structure
G.h2s4 238 F G.h2s4.01 Structure Structure
G.h2s4 239 N G.h2s4.02 Structure Structure
G.h2s4 240 D G.h2s4.03 Structure Structure
G.h2s4 241 V G.h2s4.04 Structure Structure
G.h2s4 242 T G.h2s4.05 Structure Structure
G.S4 243 A G.S4.01 Structure Structure
G.S4 244 I G.S4.02 Structure Structure
G.S4 245 I G.S4.03 Structure Structure
G.S4 246 F G.S4.04 Structure Structure
G.S4 247 V G.S4.05 Structure Structure
G.S4 248 V G.S4.06 Structure Structure
G.S4 249 A G.S4.07 Structure Structure
G.s4h3 250 S G.s4h3.01 Structure Structure
G.s4h3 251 S G.s4h3.02 AF2 AF2
G.s4h3 252 S G.s4h3.03 AF2 AF2
G.s4h3 253 Y G.s4h3.04 AF2 AF2
G.s4h3 254 N G.s4h3.05 AF2 AF2
G.s4h3 255 M G.s4h3.06 AF2 AF2
G.s4h3 256 V G.s4h3.07 AF2 AF2
G.s4h3 257 I G.s4h3.08 AF2 AF2
G.s4h3 258 R G.s4h3.09 AF2 AF2
G.s4h3 259 E G.s4h3.10 AF2 AF2
G.s4h3 260 D G.s4h3.11 AF2 AF2
G.s4h3 261 N G.s4h3.12 AF2 AF2
G.s4h3 262 Q G.s4h3.13 Structure Structure
G.s4h3 263 T G.s4h3.14 Structure Structure
G.s4h3 264 N G.s4h3.15 Structure Structure
G.H3 265 R G.H3.01 Structure Structure
G.H3 266 L G.H3.02 Structure Structure
G.H3 267 Q G.H3.03 Structure Structure
G.H3 268 E G.H3.04 Structure Structure
G.H3 269 A G.H3.05 Structure Structure
G.H3 270 L G.H3.06 Structure Structure
G.H3 271 N G.H3.07 Structure Structure
G.H3 272 L G.H3.08 Structure Structure
G.H3 273 F G.H3.09 Structure Structure
G.H3 274 K G.H3.10 Structure Structure
G.H3 275 S G.H3.11 Structure Structure
G.H3 276 I G.H3.12 Structure Structure
G.H3 277 W G.H3.13 Structure Structure
G.H3 278 N G.H3.14 Structure Structure
G.H3 279 N G.H3.15 Structure Structure
G.H3 280 R G.H3.16 Structure Structure
G.H3 281 W G.H3.17 Structure Structure
G.H3 282 L G.H3.18 Structure Structure
G.h3s5 283 R G.h3s5.01 Structure Structure
G.h3s5 284 T G.h3s5.02 Structure Structure
G.h3s5 285 I G.h3s5.03 Structure Structure
G.S5 286 S G.S5.01 Structure Structure
G.S5 287 V G.S5.02 Structure Structure
G.S5 288 I G.S5.03 Structure Structure
G.S5 289 L G.S5.04 Structure Structure
G.S5 290 F G.S5.05 Structure Structure
G.S5 291 L G.S5.06 Structure Structure
G.S5 292 N G.S5.07 Structure Structure
G.s5hg 293 K G.s5hg.01 Structure Structure
G.HG 294 Q G.HG.01 Structure Structure
G.HG 295 D G.HG.02 Structure Structure
G.HG 296 L G.HG.03 Structure Structure
G.HG 297 L G.HG.04 Structure Structure
G.HG 298 A G.HG.05 Structure Structure
G.HG 299 E G.HG.06 Structure Structure
G.HG 300 K G.HG.07 Structure Structure
G.HG 301 V G.HG.08 Structure Structure
G.HG 302 L G.HG.09 Structure Structure
G.HG 303 A G.HG.10 Structure Structure
G.HG 304 G G.HG.11 Structure Structure
G.HG 305 K G.HG.12 Structure Structure
G.HG 306 S G.HG.13 Structure Structure
G.HG 307 K G.HG.14 Structure Structure
G.HG 308 I G.HG.15 Structure Structure
G.HG 309 E G.HG.16 Structure Structure
G.HG 310 D G.HG.17 Structure Structure
G.hgh4 311 Y G.hgh4.01 Structure Structure
G.hgh4 312 F G.hgh4.02 Structure Structure
G.hgh4 313 P G.hgh4.03 Structure Structure
G.hgh4 314 E G.hgh4.04 Structure Structure
G.hgh4 315 F G.hgh4.05 Structure Structure
G.hgh4 316 A G.hgh4.06 Structure Structure
G.hgh4 317 R G.hgh4.07 Structure Structure
G.hgh4 318 Y G.hgh4.08 Structure Structure
G.hgh4 319 T G.hgh4.09 Structure Structure
G.hgh4 320 T G.hgh4.10 Structure Structure
G.hgh4 321 P G.hgh4.11 Structure Structure
G.hgh4 322 E G.hgh4.12 Structure Structure
G.hgh4 323 D G.hgh4.13 Structure Structure
G.hgh4 324 A G.hgh4.14 Structure Structure
G.hgh4 325 T G.hgh4.15 Structure Structure
G.hgh4 326 P G.hgh4.16 Structure Structure
G.hgh4 327 E G.hgh4.17 Structure Structure
G.hgh4 328 P G.hgh4.18 Structure Structure
G.hgh4 329 G G.hgh4.19 Structure Structure
G.hgh4 330 E G.hgh4.20 Structure Structure
G.hgh4 331 D G.hgh4.21 Structure Structure
G.H4 332 P G.H4.01 Structure Structure
G.H4 333 R G.H4.02 Structure Structure
G.H4 334 V G.H4.03 Structure Structure
G.H4 335 T G.H4.04 Structure Structure
G.H4 336 R G.H4.05 Structure Structure
G.H4 337 A G.H4.06 Structure Structure
G.H4 338 K G.H4.07 Structure Structure
G.H4 339 Y G.H4.08 Structure Structure
G.H4 340 F G.H4.10 Structure Structure
G.H4 341 I G.H4.11 Structure Structure
G.H4 342 R G.H4.12 Structure Structure
G.H4 343 D G.H4.13 Structure Structure
G.H4 344 E G.H4.14 Structure Structure
G.H4 345 F G.H4.15 Structure Structure
G.H4 346 L G.H4.16 Structure Structure
G.H4 347 R G.H4.17 Structure Structure
G.h4s6 348 I G.h4s6.01 Structure Structure
G.h4s6 349 S G.h4s6.02 Structure Structure
G.h4s6 350 T G.h4s6.03 Structure Structure
G.h4s6 351 A G.h4s6.04 Structure Structure
G.h4s6 352 S G.h4s6.08 Structure Structure
G.h4s6 353 G G.h4s6.09 Structure Structure
G.h4s6 354 D G.h4s6.10 Structure Structure
G.h4s6 355 G G.h4s6.11 Structure Structure
G.h4s6 356 R G.h4s6.12 Structure Structure
G.h4s6 357 H G.h4s6.13 Structure Structure
G.h4s6 358 Y G.h4s6.20 Structure Structure
G.S6 359 C G.S6.01 Structure Structure
G.S6 360 Y G.S6.02 Structure Structure
G.S6 361 P G.S6.03 Structure Structure
G.S6 362 H G.S6.04 Structure Structure
G.S6 363 F G.S6.05 Structure Structure
G.s6h5 364 T G.s6h5.01 Structure Structure
G.s6h5 365 C G.s6h5.02 Structure Structure
G.s6h5 366 A G.s6h5.03 Structure Structure
G.s6h5 367 V G.s6h5.04 Structure Structure
G.s6h5 368 D G.s6h5.05 Structure Structure
G.H5 369 T G.H5.01 Structure Structure
G.H5 370 E G.H5.02 Structure Structure
G.H5 371 N G.H5.03 Structure Structure
G.H5 372 I G.H5.04 Structure Structure
G.H5 373 R G.H5.05 Structure Structure
G.H5 374 R G.H5.06 Structure Structure
G.H5 375 V G.H5.07 Structure Structure
G.H5 376 F G.H5.08 Structure Structure
G.H5 377 N G.H5.09 Structure Structure
G.H5 378 D G.H5.10 Structure Structure
G.H5 379 C G.H5.11 Structure Structure
G.H5 380 R G.H5.12 Structure Structure
G.H5 381 D G.H5.13 Structure Structure
G.H5 382 I G.H5.14 Structure Structure
G.H5 383 I G.H5.15 Structure Structure
G.H5 384 Q G.H5.16 Structure Structure
G.H5 385 R G.H5.17 Structure Structure
G.H5 386 M G.H5.18 Structure Structure
G.H5 387 H G.H5.19 Structure Structure
G.H5 388 L G.H5.20 Structure Structure
G.H5 389 R G.H5.21 Structure Structure
G.H5 390 Q G.H5.22 Structure Structure
G.H5 391 Y G.H5.23 Structure Structure
G.H5 392 E G.H5.24 Structure Structure
G.H5 393 L G.H5.25 Structure Structure
G.H5 394 L G.H5.26 AF2 AF2

REFINED GPCR RESIDUES

Residue backbones - 277 from structure (88.2%), 37 from model (11.8%)
Residue sidechains - 28 from structure (8.9%), 286 from model (91.1%)
Segment Seq.num. AA GPCRdb# Backbone from Sidechain from
N-term 1 M - AF2 AF2
N-term 2 A - AF2 AF2
N-term 3 P - AF2 AF2
N-term 4 N - AF2 AF2
N-term 5 G - AF2 AF2
N-term 6 T - AF2 AF2
N-term 7 A - AF2 AF2
N-term 8 S - AF2 AF2
N-term 9 S - AF2 AF2
TM1 10 F 1.24x24 AF2 AF2
TM1 11 C 1.25x25 AF2 AF2
TM1 12 L 1.26x26 AF2 AF2
TM1 13 D 1.27x27 AF2 AF2
TM1 14 S 1.28x28 AF2 AF2
TM1 15 T 1.29x29 AF2 AF2
TM1 16 A 1.30x30 AF2 AF2
TM1 17 C 1.31x31 AF2 AF2
TM1 18 K 1.32x32 AF2 AF2
TM1 19 I 1.33x33 AF2 AF2
TM1 20 T 1.34x34 Structure AF2
TM1 21 I 1.35x35 Structure AF2
TM1 22 T 1.36x36 Structure AF2
TM1 23 V 1.37x37 Structure AF2
TM1 24 V 1.38x38 Structure AF2
TM1 25 L 1.39x39 Structure AF2
TM1 26 A 1.40x40 Structure AF2
TM1 27 V 1.41x41 Structure AF2
TM1 28 L 1.42x42 Structure AF2
TM1 29 I 1.43x43 Structure AF2
TM1 30 L 1.44x44 Structure AF2
TM1 31 I 1.45x45 Structure AF2
TM1 32 T 1.46x46 Structure AF2
TM1 33 V 1.47x47 Structure Structure
TM1 34 A 1.48x48 Structure AF2
TM1 35 G 1.49x49 Structure AF2
TM1 36 N 1.50x50 Structure AF2
TM1 37 V 1.51x51 Structure AF2
TM1 38 V 1.52x52 Structure AF2
TM1 39 V 1.53x53 Structure Structure
TM1 40 C 1.54x54 Structure AF2
TM1 41 L 1.55x55 Structure AF2
TM1 42 A 1.56x56 Structure AF2
TM1 43 V 1.57x57 Structure Structure
TM1 44 G 1.58x58 Structure AF2
TM1 45 L 1.59x59 Structure AF2
TM1 46 N 1.60x60 Structure AF2
ICL1 47 R 12.48x48 Structure AF2
ICL1 48 R 12.49x49 Structure AF2
ICL1 49 L 12.50x50 Structure AF2
ICL1 50 R 12.51x51 Structure AF2
TM2 51 N 2.37x37 Structure AF2
TM2 52 L 2.38x38 Structure AF2
TM2 53 T 2.39x39 Structure AF2
TM2 54 N 2.40x40 Structure AF2
TM2 55 C 2.41x41 Structure AF2
TM2 56 F 2.42x42 Structure AF2
TM2 57 I 2.43x43 Structure AF2
TM2 58 V 2.44x44 Structure AF2
TM2 59 S 2.45x45 Structure AF2
TM2 60 L 2.46x46 Structure AF2
TM2 61 A 2.47x47 Structure AF2
TM2 62 I 2.48x48 Structure AF2
TM2 63 T 2.49x49 Structure AF2
TM2 64 D 2.50x50 Structure AF2
TM2 65 L 2.51x51 Structure AF2
TM2 66 L 2.52x52 Structure Structure
TM2 67 L 2.53x53 Structure AF2
TM2 68 G 2.54x54 Structure AF2
TM2 69 L 2.55x55 Structure AF2
TM2 70 L 2.56x551 Structure AF2
TM2 71 V 2.57x56 Structure AF2
TM2 72 L 2.58x57 Structure Structure
TM2 73 P 2.59x58 Structure AF2
TM2 74 F 2.60x59 Structure AF2
TM2 75 S 2.61x60 Structure AF2
TM2 76 A 2.62x61 Structure AF2
TM2 77 I 2.63x62 Structure AF2
TM2 78 Y 2.64x63 Structure AF2
TM2 79 Q 2.65x64 Structure AF2
TM2 80 L 2.66x65 Structure AF2
TM2 81 S 2.67x66 Structure Structure
TM2 82 C 2.68x67 Structure AF2
ECL1 83 K 23.49x49 Structure AF2
ECL1 84 W 23.50x50 Structure AF2
ECL1 85 S 23.51x51 Structure AF2
ECL1 86 F 23.52x52 Structure AF2
TM3 87 G 3.21x21 Structure AF2
TM3 88 K 3.22x22 Structure AF2
TM3 89 V 3.23x23 Structure AF2
TM3 90 F 3.24x24 Structure AF2
TM3 91 C 3.25x25 Structure AF2
TM3 92 N 3.26x26 Structure AF2
TM3 93 I 3.27x27 Structure AF2
TM3 94 Y 3.28x28 Structure AF2
TM3 95 T 3.29x29 Structure AF2
TM3 96 S 3.30x30 Structure AF2
TM3 97 L 3.31x31 Structure AF2
TM3 98 D 3.32x32 Structure AF2
TM3 99 V 3.33x33 Structure AF2
TM3 100 M 3.34x34 Structure AF2
TM3 101 L 3.35x35 Structure AF2
TM3 102 C 3.36x36 Structure AF2
TM3 103 T 3.37x37 Structure AF2
TM3 104 A 3.38x38 Structure AF2
TM3 105 S 3.39x39 Structure AF2
TM3 106 I 3.40x40 Structure AF2
TM3 107 L 3.41x41 Structure Structure
TM3 108 N 3.42x42 Structure AF2
TM3 109 L 3.43x43 Structure AF2
TM3 110 F 3.44x44 Structure AF2
TM3 111 M 3.45x45 Structure AF2
TM3 112 I 3.46x46 Structure Structure
TM3 113 S 3.47x47 Structure AF2
TM3 114 L 3.48x48 Structure AF2
TM3 115 D 3.49x49 Structure AF2
TM3 116 R 3.50x50 Structure AF2
TM3 117 Y 3.51x51 Structure AF2
TM3 118 C 3.52x52 Structure AF2
TM3 119 A 3.53x53 Structure AF2
TM3 120 V 3.54x54 Structure AF2
TM3 121 M 3.55x55 Structure AF2
TM3 122 D 3.56x56 Structure AF2
ICL2 123 P 34.50x50 Structure AF2
ICL2 124 L 34.51x51 Structure AF2
ICL2 125 R 34.52x52 Structure AF2
ICL2 126 Y 34.53x53 Structure AF2
ICL2 127 P 34.54x54 Structure AF2
ICL2 128 V 34.55x55 Structure AF2
ICL2 129 L 34.56x56 Structure AF2
ICL2 130 V 34.57x57 Structure AF2
TM4 131 T 4.38x38 Structure AF2
TM4 132 P 4.39x39 Structure AF2
TM4 133 V 4.40x40 Structure AF2
TM4 134 R 4.41x41 Structure AF2
TM4 135 V 4.42x42 Structure AF2
TM4 136 A 4.43x43 Structure AF2
TM4 137 I 4.44x44 Structure AF2
TM4 138 S 4.45x45 Structure AF2
TM4 139 L 4.46x46 Structure AF2
TM4 140 V 4.47x47 Structure AF2
TM4 141 L 4.48x48 Structure AF2
TM4 142 I 4.49x49 Structure AF2
TM4 143 W 4.50x50 Structure AF2
TM4 144 V 4.51x51 Structure AF2
TM4 145 I 4.52x52 Structure AF2
TM4 146 S 4.53x53 Structure AF2
TM4 147 I 4.54x54 Structure AF2
TM4 148 T 4.55x55 Structure AF2
TM4 149 L 4.56x56 Structure AF2
TM4 150 S 4.57x57 Structure AF2
TM4 151 F 4.58x58 Structure AF2
TM4 152 L 4.59x59 Structure AF2
TM4 153 S 4.60x60 Structure AF2
TM4 154 I 4.61x61 Structure AF2
TM4 155 H 4.62x62 Structure AF2
TM4 156 L 4.63x63 Structure AF2
TM4 157 G 4.64x64 Structure AF2
ECL2 158 W - Structure AF2
ECL2 159 N - Structure AF2
ECL2 160 S - Structure AF2
ECL2 161 R - Structure AF2
ECL2 162 N - Structure AF2
ECL2 163 E - Structure AF2
ECL2 164 T - Structure AF2
ECL2 165 S - Structure AF2
ECL2 166 K - Structure AF2
ECL2 167 G - Structure AF2
ECL2 168 N - Structure Structure
ECL2 169 H - Structure AF2
ECL2 170 T - AF2 AF2
ECL2 171 T - AF2 AF2
ECL2 172 S - AF2 AF2
ECL2 173 K - AF2 AF2
ECL2 174 C 45.50x50 AF2 AF2
ECL2 175 K 45.51x51 AF2 AF2
ECL2 176 V 45.52x52 AF2 AF2
ECL2 177 Q - AF2 AF2
ECL2 178 V - Structure Structure
TM5 179 N 5.35x36 Structure Structure
TM5 180 E 5.36x37 Structure AF2
TM5 181 V 5.37x38 Structure AF2
TM5 182 Y 5.38x39 Structure AF2
TM5 183 G 5.39x40 Structure Structure
TM5 184 L 5.40x41 Structure Structure
TM5 185 V 5.41x42 Structure Structure
TM5 186 D 5.42x43 Structure Structure
TM5 187 G 5.43x44 Structure Structure
TM5 188 L 5.44x45 Structure AF2
TM5 189 V 5.45x46 Structure AF2
TM5 190 T 5.46x461 Structure AF2
TM5 191 F 5.47x47 Structure AF2
TM5 192 Y 5.48x48 Structure AF2
TM5 193 L 5.49x49 Structure AF2
TM5 194 P 5.50x50 Structure AF2
TM5 195 L 5.51x51 Structure AF2
TM5 196 L 5.52x52 Structure AF2
TM5 197 I 5.53x53 Structure AF2
TM5 198 M 5.54x54 Structure AF2
TM5 199 C 5.55x55 Structure AF2
TM5 200 I 5.56x56 Structure AF2
TM5 201 T 5.57x57 Structure AF2
TM5 202 Y 5.58x58 Structure AF2
TM5 203 Y 5.59x59 Structure AF2
TM5 204 R 5.60x60 Structure AF2
TM5 205 I 5.61x61 Structure AF2
TM5 206 F 5.62x62 Structure AF2
TM5 207 K 5.63x63 Structure AF2
TM5 208 V 5.64x64 Structure AF2
TM5 209 A 5.65x65 Structure AF2
TM5 210 R 5.66x66 Structure Structure
TM5 211 D 5.67x67 Structure AF2
TM5 212 Q 5.68x68 Structure AF2
TM5 213 A 5.69x69 Structure AF2
TM5 214 K 5.70x70 Structure AF2
TM5 215 R 5.71x71 Structure AF2
TM5 216 I 5.72x72 Structure AF2
TM5 217 N 5.73x73 Structure AF2
ICL3 218 H - Structure AF2
ICL3 219 I - Structure AF2
ICL3 220 S - Structure AF2
TM6 221 S 6.22x22 Structure AF2
TM6 222 W 6.23x23 Structure AF2
TM6 223 K 6.24x24 Structure AF2
TM6 224 A 6.25x25 Structure AF2
TM6 225 A 6.26x26 Structure AF2
TM6 226 T 6.27x27 Structure AF2
TM6 227 I 6.28x28 Structure AF2
TM6 228 R 6.29x29 Structure AF2
TM6 229 E 6.30x30 Structure AF2
TM6 230 H 6.31x31 Structure AF2
TM6 231 K 6.32x32 Structure AF2
TM6 232 A 6.33x33 Structure AF2
TM6 233 T 6.34x34 Structure AF2
TM6 234 V 6.35x35 Structure AF2
TM6 235 T 6.36x36 Structure AF2
TM6 236 L 6.37x37 Structure AF2
TM6 237 A 6.38x38 Structure AF2
TM6 238 A 6.39x39 Structure Structure
TM6 239 V 6.40x40 Structure AF2
TM6 240 M 6.41x41 Structure AF2
TM6 241 G 6.42x42 Structure AF2
TM6 242 A 6.43x43 Structure AF2
TM6 243 F 6.44x44 Structure AF2
TM6 244 I 6.45x45 Structure AF2
TM6 245 I 6.46x46 Structure AF2
TM6 246 C 6.47x47 Structure AF2
TM6 247 W 6.48x48 Structure AF2
TM6 248 F 6.49x49 Structure AF2
TM6 249 P 6.50x50 Structure AF2
TM6 250 Y 6.51x51 Structure AF2
TM6 251 F 6.52x52 Structure AF2
TM6 252 T 6.53x53 Structure AF2
TM6 253 A 6.54x54 Structure AF2
TM6 254 F 6.55x55 Structure Structure
TM6 255 V 6.56x56 Structure AF2
TM6 256 Y 6.57x57 Structure Structure
TM6 257 R 6.58x58 Structure AF2
TM6 258 G 6.59x59 Structure AF2
TM6 259 L 6.60x60 Structure AF2
TM6 260 R 6.61x61 Structure AF2
ECL3 261 G - Structure AF2
ECL3 262 D - Structure AF2
ECL3 263 D - Structure AF2
ECL3 264 A - Structure AF2
ECL3 265 I - Structure AF2
TM7 266 N 7.31x30 Structure AF2
TM7 267 E 7.32x31 Structure AF2
TM7 268 V 7.33x32 Structure AF2
TM7 269 L 7.34x33 Structure AF2
TM7 270 E 7.35x34 Structure AF2
TM7 271 A 7.36x35 Structure AF2
TM7 272 I 7.37x36 Structure AF2
TM7 273 V 7.38x37 Structure AF2
TM7 274 L 7.39x38 Structure AF2
TM7 275 W 7.40x39 Structure AF2
TM7 276 L 7.41x40 Structure AF2
TM7 277 G 7.42x41 Structure AF2
TM7 278 Y 7.43x42 Structure AF2
TM7 279 A 7.44x43 Structure AF2
TM7 280 N 7.45x45 Structure AF2
TM7 281 S 7.46x46 Structure AF2
TM7 282 A 7.47x47 Structure AF2
TM7 283 L 7.48x48 Structure AF2
TM7 284 N 7.49x49 Structure AF2
TM7 285 P 7.50x50 Structure AF2
TM7 286 I 7.51x51 Structure AF2
TM7 287 L 7.52x52 Structure AF2
TM7 288 Y 7.53x53 Structure AF2
TM7 289 A 7.54x54 Structure AF2
TM7 290 A 7.55x55 Structure AF2
TM7 291 L 7.56x56 Structure AF2
H8 292 N 8.47x47 Structure AF2
H8 293 R 8.48x48 Structure AF2
H8 294 D 8.49x49 Structure AF2
H8 295 F 8.50x50 Structure AF2
H8 296 R 8.51x51 Structure AF2
H8 297 T 8.52x52 Structure Structure
H8 298 G 8.53x53 Structure Structure
H8 299 Y 8.54x54 Structure Structure
H8 300 Q 8.55x55 Structure Structure
H8 301 Q 8.56x56 Structure Structure
H8 302 L 8.57x57 Structure Structure
H8 303 F 8.58x58 Structure Structure
H8 304 C 8.59x59 Structure Structure
C-term 305 C - AF2 AF2
C-term 306 R - AF2 AF2
C-term 307 L - AF2 AF2
C-term 308 A - AF2 AF2
C-term 309 N - AF2 AF2
C-term 310 R - AF2 AF2
C-term 311 N - AF2 AF2
C-term 312 S - AF2 AF2
C-term 313 H - AF2 AF2
C-term 314 K - AF2 AF2



GPCR - G protein interface interactions



The biflare plot is a modified version of a flareplot, where lines are drawn between an inner concentric circle (Gα residues) and an outer concentric circle (GPCR residues) depicting the interface interactions.
Different interaction types are shown with different line types (aromatic - solid, hydrophobic - dashed, ionic - long dashed, polar - dotted, Van der Waals - dash-dot).
The interactive features include filtering on interaction type, segments, residues and backbone or sidechain interactions.


Interaction cut-off:

Residue numbering:

GPCR-G protein backbone (bb) or sidechain (sc):





Structures

Sequence Color

Gα, Gβ, Gγ, GPCR
Interaction cut-off: strict (stick), loose (line)

NGL is a WebGL based 3D viewer powered by MMTF.

Interaction
type		 GPCR
Segment
AA
Number		 Generic
number		 Gα
segment
AA
Number		 Generic
number
Polar C-term H 313 - G.H3 W 277 G.H3.13
Aromatic C-term H 313 - G.H3 W 277 G.H3.13
Hydrophobic C-term H 313 - G.H3 W 277 G.H3.13
Van-der-waals C-term H 313 - G.H3 W 277 G.H3.13
Hydrophobic C-term H 313 - G.h4s6 G 355 G.h4s6.11
Van-der-waals C-term H 313 - G.h4s6 G 355 G.h4s6.11
Polar C-term K 314 - G.h4s6 D 354 G.h4s6.10
Hydrophobic C-term K 314 - G.h4s6 D 354 G.h4s6.10
Van-der-waals C-term K 314 - G.h4s6 D 354 G.h4s6.10
Hydrophobic C-term S 312 - G.h4s6 D 354 G.h4s6.10
Van-der-waals C-term S 312 - G.h4s6 D 354 G.h4s6.10
Hydrophobic H8 T 297 8x52 G.H5 Q 390 G.H5.22
Van-der-waals H8 T 297 8x52 G.H5 Q 390 G.H5.22
Polar C-term N 309 - G.h4s6 R 356 G.h4s6.12
Hydrophobic C-term N 309 - G.h4s6 R 356 G.h4s6.12
Van-der-waals C-term N 309 - G.h4s6 R 356 G.h4s6.12
Polar H8 Q 300 8x55 G.H5 E 392 G.H5.24
Hydrophobic H8 Q 300 8x55 G.H5 E 392 G.H5.24
Van-der-waals H8 Q 300 8x55 G.H5 E 392 G.H5.24
Polar ICL3 H 218 - G.H5 R 385 G.H5.17
Hydrophobic ICL3 H 218 - G.H5 R 385 G.H5.17
Van-der-waals ICL3 H 218 - G.H5 R 385 G.H5.17
Polar C-term C 305 - G.h4s6 R 356 G.h4s6.12
Hydrophobic C-term C 305 - G.h4s6 R 356 G.h4s6.12
Van-der-waals C-term C 305 - G.h4s6 R 356 G.h4s6.12
Hydrophobic H8 T 297 8x52 G.H5 Y 391 G.H5.23
Van-der-waals H8 T 297 8x52 G.H5 Y 391 G.H5.23
Polar C-term H 313 - G.h4s6 Y 358 G.h4s6.20
Hydrophobic C-term H 313 - G.h4s6 Y 358 G.h4s6.20
Van-der-waals C-term H 313 - G.h4s6 Y 358 G.h4s6.20
Hydrophobic ICL2 L 129 34x56 G.H5 H 387 G.H5.19
Van-der-waals ICL2 L 129 34x56 G.H5 H 387 G.H5.19
Polar C-term N 309 - G.h3s5 R 283 G.h3s5.01
Hydrophobic C-term N 309 - G.h3s5 R 283 G.h3s5.01
Van-der-waals C-term N 309 - G.h3s5 R 283 G.h3s5.01
Polar ICL2 R 125 34x52 G.H5 Y 391 G.H5.23
Hydrophobic ICL2 R 125 34x52 G.H5 Y 391 G.H5.23
Van-der-waals ICL2 R 125 34x52 G.H5 Y 391 G.H5.23
Hydrophobic TM5 R 215 5x71 G.H5 L 393 G.H5.25
Van-der-waals TM5 R 215 5x71 G.H5 L 393 G.H5.25
Hydrophobic ICL2 L 129 34x56 G.H5 Q 384 G.H5.16
Van-der-waals ICL2 L 129 34x56 G.H5 Q 384 G.H5.16
Polar C-term N 311 - G.h4s6 G 355 G.h4s6.11
Polar TM3 D 122 3x56 G.H5 Y 391 G.H5.23
Hydrophobic TM3 D 122 3x56 G.H5 Y 391 G.H5.23
Van-der-waals TM3 D 122 3x56 G.H5 Y 391 G.H5.23
Hydrophobic TM6 I 227 6x28 G.hgh4 P 321 G.hgh4.11
Van-der-waals C-term H 313 - G.h4s6 S 349 G.h4s6.02
Hydrophobic ICL2 V 130 34x57 G.S1 H 41 G.S1.02
Van-der-waals ICL2 V 130 34x57 G.S1 H 41 G.S1.02
Van-der-waals TM4 R 134 4x41 G.S3 V 217 G.S3.01
Hydrophobic ICL2 L 129 34x56 G.H5 I 383 G.H5.15
Van-der-waals ICL2 L 129 34x56 G.H5 I 383 G.H5.15
Hydrophobic ICL2 V 130 34x57 G.S3 V 217 G.S3.01
Van-der-waals ICL2 V 130 34x57 G.S3 V 217 G.S3.01
Polar C-term H 313 - G.h4s6 G 353 G.h4s6.09
Hydrophobic C-term H 313 - G.h4s6 G 353 G.h4s6.09
Van-der-waals C-term H 313 - G.h4s6 G 353 G.h4s6.09
Hydrophobic C-term A 308 - G.H5 R 389 G.H5.21
Van-der-waals C-term A 308 - G.H5 R 389 G.H5.21
Hydrophobic C-term K 314 - G.H5 L 394 G.H5.26
Polar C-term N 309 - G.h3s5 T 284 G.h3s5.02
Hydrophobic C-term N 309 - G.h3s5 T 284 G.h3s5.02
Van-der-waals C-term N 309 - G.h3s5 T 284 G.h3s5.02
Hydrophobic TM6 T 226 6x27 G.H4 L 346 G.H4.16
Polar C-term N 311 - G.h4s6 D 354 G.h4s6.10
Hydrophobic C-term N 311 - G.h4s6 D 354 G.h4s6.10
Van-der-waals C-term N 311 - G.h4s6 D 354 G.h4s6.10
Hydrophobic C-term R 310 - G.h4s6 G 353 G.h4s6.09
Van-der-waals C-term R 310 - G.h4s6 G 353 G.h4s6.09
Hydrophobic TM4 T 131 4x38 G.S3 V 217 G.S3.01
Polar TM6 W 222 6x23 G.h4s6 Y 358 G.h4s6.20
Aromatic TM6 W 222 6x23 G.h4s6 Y 358 G.h4s6.20
Hydrophobic TM6 W 222 6x23 G.h4s6 Y 358 G.h4s6.20
Van-der-waals TM6 W 222 6x23 G.h4s6 Y 358 G.h4s6.20
Polar C-term S 312 - G.H5 R 389 G.H5.21
Polar H8 Q 301 8x56 G.H5 Q 390 G.H5.22
Hydrophobic H8 Q 301 8x56 G.H5 Q 390 G.H5.22
Van-der-waals H8 Q 301 8x56 G.H5 Q 390 G.H5.22
Polar C-term S 312 - G.h4s6 G 355 G.h4s6.11
Hydrophobic C-term S 312 - G.h4s6 G 355 G.h4s6.11
Van-der-waals C-term S 312 - G.h4s6 G 355 G.h4s6.11
Polar C-term H 313 - G.h4s6 S 352 G.h4s6.08
Hydrophobic C-term H 313 - G.h4s6 S 352 G.h4s6.08
Van-der-waals C-term H 313 - G.h4s6 S 352 G.h4s6.08
Hydrophobic TM6 R 228 6x29 G.hgh4 Y 318 G.hgh4.08
Van-der-waals TM6 R 228 6x29 G.hgh4 Y 318 G.hgh4.08
Hydrophobic ICL3 H 218 - G.H5 L 394 G.H5.26
Van-der-waals ICL3 H 218 - G.H5 L 394 G.H5.26
Hydrophobic C-term N 311 - G.h4s6 G 353 G.h4s6.09
Van-der-waals C-term N 311 - G.h4s6 G 353 G.h4s6.09
Hydrophobic C-term A 308 - G.h4s6 R 356 G.h4s6.12
Van-der-waals C-term A 308 - G.h4s6 R 356 G.h4s6.12
Hydrophobic ICL2 Y 126 34x53 G.H5 L 388 G.H5.20
Van-der-waals ICL2 Y 126 34x53 G.H5 L 388 G.H5.20
Hydrophobic TM5 R 215 5x71 G.H5 L 388 G.H5.20
Van-der-waals TM5 R 215 5x71 G.H5 L 388 G.H5.20
Hydrophobic C-term K 314 - G.h4s6 T 350 G.h4s6.03
Polar ICL2 Y 126 34x53 G.H5 Q 384 G.H5.16
Hydrophobic ICL2 Y 126 34x53 G.H5 Q 384 G.H5.16
Van-der-waals ICL2 Y 126 34x53 G.H5 Q 384 G.H5.16
Polar C-term S 312 - G.h4s6 G 353 G.h4s6.09
Hydrophobic C-term S 312 - G.h4s6 G 353 G.h4s6.09
Van-der-waals C-term S 312 - G.h4s6 G 353 G.h4s6.09
Hydrophobic TM4 I 137 4x44 G.HN Q 35 G.HN.52
Van-der-waals TM4 I 137 4x44 G.HN Q 35 G.HN.52
Polar C-term H 313 - G.h4s6 H 357 G.h4s6.13
Aromatic C-term H 313 - G.h4s6 H 357 G.h4s6.13
Hydrophobic C-term H 313 - G.h4s6 H 357 G.h4s6.13
Van-der-waals C-term H 313 - G.h4s6 H 357 G.h4s6.13
Polar C-term H 313 - G.h4s6 D 354 G.h4s6.10
Hydrophobic C-term H 313 - G.h4s6 D 354 G.h4s6.10
Van-der-waals C-term H 313 - G.h4s6 D 354 G.h4s6.10
Polar C-term K 314 - G.h4s6 G 355 G.h4s6.11
Hydrophobic C-term K 314 - G.h4s6 G 355 G.h4s6.11
Van-der-waals C-term K 314 - G.h4s6 G 355 G.h4s6.11
Polar C-term C 305 - G.H5 R 389 G.H5.21
Hydrophobic TM4 V 133 4x40 G.hns1 R 38 G.hns1.02
Van-der-waals TM4 V 133 4x40 G.hns1 R 38 G.hns1.02
Van-der-waals C-term H 313 - G.h4s6 R 356 G.h4s6.12
Hydrophobic ICL2 V 130 34x57 G.H5 R 380 G.H5.12
Polar TM4 R 134 4x41 G.hns1 A 39 G.hns1.03
Hydrophobic TM4 R 134 4x41 G.hns1 A 39 G.hns1.03
Van-der-waals TM4 R 134 4x41 G.hns1 A 39 G.hns1.03
Aromatic ICL2 R 125 34x52 G.H5 H 387 G.H5.19
Hydrophobic ICL2 R 125 34x52 G.H5 H 387 G.H5.19
Polar C-term S 312 - G.h4s6 H 357 G.h4s6.13
Van-der-waals C-term S 312 - G.h4s6 H 357 G.h4s6.13
Polar TM4 R 134 4x41 G.s2s3 K 216 G.s2s3.02
Hydrophobic TM4 R 134 4x41 G.s2s3 K 216 G.s2s3.02
Van-der-waals TM4 R 134 4x41 G.s2s3 K 216 G.s2s3.02
Hydrophobic C-term R 310 - G.h3s5 R 283 G.h3s5.01
Van-der-waals C-term R 310 - G.h3s5 R 283 G.h3s5.01
Polar C-term K 314 - G.h4s6 Y 358 G.h4s6.20
Hydrophobic C-term K 314 - G.h4s6 Y 358 G.h4s6.20
Van-der-waals C-term K 314 - G.h4s6 Y 358 G.h4s6.20
Polar C-term S 312 - G.h4s6 R 356 G.h4s6.12
Hydrophobic C-term S 312 - G.h4s6 R 356 G.h4s6.12
Van-der-waals C-term S 312 - G.h4s6 R 356 G.h4s6.12