Structure information

TAS2R14

PROTEIN CLASS

Class T2 (Taste 2)

PDB CODE

8VY9

SPECIES

Homo sapiens

RESOLUTION

2.880

PREFERRED CHAIN

R

REFERENCE

PUBLICATION DATE

April 3, 2024

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
compound 28.1 [PMID: 36847646] Y107 3.50x50 TM3 hydrophobic
compound 28.1 [PMID: 36847646] M197 5.57x57 TM5 hydrophobic
compound 28.1 [PMID: 36847646] F198 5.58x58 TM5 aromatic (edge-to-face)
compound 28.1 [PMID: 36847646] L201 5.61x61 TM5 hydrophobic
compound 28.1 [PMID: 36847646] V230 6.35x35 TM6 hydrophobic
compound 28.1 [PMID: 36847646] V233 6.38x38 TM6 hydrophobic
compound 28.1 [PMID: 36847646] F237 6.42x42 TM6 aromatic (face-to-edge)
compound 28.1 [PMID: 36847646] H276 7.49x49 TM7 polar (hydrogen bond)
compound 28.1 [PMID: 36847646] H276 7.49x49 TM7 Van der Waals
compound 28.1 [PMID: 36847646] G283 7.56x56 TM7 Van der Waals

Ligands

compound 28.1 [PMID: 36847646]

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Residue Diagrams

S N G L N G I I F E V I L V F T F I S K 1 T A L A I S R I S L V W L I F G S W C V 2 G T A L W V S F H N I V T W I N T L M R 3 V L V L L L V T S V F L F L N I A L I N 4 F M A L S L T F P I F I F V T S T L V I 5 V I T F F L L Y A I F S L S F F I S V W 6 C S H C S P Y A M G M V Q S L I I L N 7
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ICL1 R K I ICL1ECL1 P A L F A ECL1ICL2 N F S N S I F L Y L K W ICL2ECL2 A S I N G Y R R N K T C S S D S S N F T R F S S L ECL2ICL3 K I S G D A S T K A ICL3ECL3 E E ECL3C-term G E P S G H K E F R E S S C-term M G G V I K S I F T F V L I V E F I I G N L G N S F I A L V N C I D W V K G S S V D R I L T A L A I S R I S L V W L I F G S W C V S V F F T E K M F R M L T N I W T V I N H F S V W L A T G L G T F Y F L K I A R V K K V V L V L L L V T S V F L F L N I A L I N I H I N I V L T S T V F I F I P F T L S L A M F L L L I F S M W K H R K K M Q H T V H R G V K S V I T F F L L Y A I F S L S F F I S V W T S E R L N L I I L S Q V M G M A Y P S C H S C V L I L G N K K S L S L R Y L R Q A V L L W M F K D
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Residue Table


GPCRdb(A)
GPCRdb(A)
TAS2R14
TM3
3x50 3.50x50 Y107
TM5
5x57 5.57x57 M197
5x58 5.58x58 F198
5x61 5.61x61 L201
TM6
6x35 6.35x35 V230
6x38 6.38x38 V233
6x42 6.42x42 F237
TM7
7x49 7.49x49 H276
7x56 7.56x56 G283