GproteinDb

K185

Agent/drug
Bioactivity

K185

SMILES	CCCC(=O)NCCc1c2n(c3ccc(OC)cc13)CCCc1ccccc1-2
InChIKey	SPIFQXPRSJKRAO-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	3
Hydrogen bond donors	1
Rotatable bonds	6
Molecular weight (Da)	376.2

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

MT₁	MTR1A	Human	Melatonin	A	pKi	7.20	7.20	7.20	Guide to Pharmacology
MT₁	MTR1A	Human	Melatonin	A	pKi	7.18	7.18	7.18	ChEMBL
MT₂	MTR1B	Human	Melatonin	A	pKi	9.29	9.29	9.29	Guide to Pharmacology
MT₂	MTR1B	Human	Melatonin	A	pKi	9.30	9.30	9.30	ChEMBL

Showing 1 to 4 of 4 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

M₁	ACM1	Rat	Acetylcholine (muscarinic)	A	Potency	5.10	5.10	5.10	ChEMBL
NPS	NPSR1	Human	Neuropeptide S	A	Potency	4.90	4.90	4.90	ChEMBL
TSH	TSHR	Human	Glycoprotein hormone	A	Potency	5.10	5.10	5.10	ChEMBL

Showing 1 to 3 of 3 entries

K185

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids GPCRdb

Compound is not listed as a drug.