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Construct Crystallization Sequence modifications
PDB UniProt Receptor Rec. Family Class Species Method Mutations Deletions Modifications Insertions PDB Resolution Reference Date
2R4R ADRB2 β2 Adrenoceptors A (Rhodopsin) Human vapour diffusion 2 1 0 4 2R4R 3.4 2007-11-06
8CU7 AA2AR A2A Adenosine A (Rhodopsin) Human N/A 0 3 0 0 8CU7 2.1 10.1021/acs.jmedchem.2c00462 2022-08-31
6PT2 OPRD δ Opioid A (Rhodopsin) Human N/A 0 2 0 0 6PT2 2.8 10.1126/SCIADV.AAX9115 2019-12-11
7EW2 S1PR3 S1P3 Lysophospholipid (S1P) A (Rhodopsin) Human N/A 0 0 0 0 7EW2 3.1 10.1038/S41422-021-00567-W 2021-09-29
7FIG LSHR LH Glycoprotein hormone A (Rhodopsin) Human N/A 0 1 0 0 7FIG 3.9 10.1038/S41586-021-03924-2 2021-09-29
7EXD 5HT1F 5-HT1F 5-Hydroxytryptamine A (Rhodopsin) Human N/A 0 0 0 0 7EXD 3.4 10.1038/S41422-021-00527-4 2021-08-04
7EVM GLP1R GLP-1 Glucagon B1 (Secretin) Human N/A 0 1 0 0 7EVM 2.5 10.1038/S41467-021-24058-Z 2021-08-11
7FII LSHR LH Glycoprotein hormone A (Rhodopsin) Human N/A 0 1 0 0 7FII 4.3 10.1038/S41586-021-03924-2 2021-09-29
6DO1 AGTR1 AT1 Angiotensin A (Rhodopsin) Human N/A 0 2 0 2 6DO1 2.9 10.1016/J.CELL.2018.12.006 2019-01-30
7S8N MRGX2 MRGPRX2 A orphans A (Rhodopsin) Human N/A 0 1 0 0 7S8N 2.9 10.1038/S41586-021-04126-6 2021-11-17
7S8M MRGX2 MRGPRX2 A orphans A (Rhodopsin) Human N/A 0 1 0 0 7S8M 2.5 10.1038/S41586-021-04126-6 2021-11-17
6RZ4 CLTR1 CysLT1 Leukotriene A (Rhodopsin) Human N/A 0 1 0 4 6RZ4 2.7 10.1126/SCIADV.AAX2518 2019-10-30
3PWH AA2AR A2A Adenosine A (Rhodopsin) Human vapour diffusion 8 1 0 2 3PWH 3.3 10.1016/J.STR.2011.06.014 2011-09-07
5WB2 Q80KM9 US28 Unclassified A (Rhodopsin) strain AD169 in meso/LCP 0 1 0 9 5WB2 3.5 10.7554/ELIFE.35850 2018-06-13
7JOZ DRD1 D1 Dopamine A (Rhodopsin) Human N/A 0 2 0 0 7JOZ 3.8 10.1038/S41467-021-23519-9 2021-04-14
7F54 MC4R MC4 Melanocortin A (Rhodopsin) Human N/A 0 0 0 0 7F54 3.0 2021-11-03
7CX4 PE2R2 EP2 Prostanoid A (Rhodopsin) Human N/A 0 0 0 0 7CX4 2.9 10.1126/SCIADV.ABF1268 2021-05-05
7F1R CCR5 CCR5 Chemokine A (Rhodopsin) Human N/A 1 1 0 0 7F1R 3.0 2021-07-14
5ZK3 ACM2 M2 Acetylcholine (muscarinic) A (Rhodopsin) Human N/A 0 2 0 5 5ZK3 2.6 10.1038/S41589-018-0152-Y 2018-11-21
8QOT OPRM μ Opioid A (Rhodopsin) Mouse N/A 0 1 0 0 8QOT 3.2 10.1101/2023.12.06.570395 2023-12-27
8JJ8 ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 3 0 0 8JJ8 3.2 10.1038/S41589-023-01389-0 2023-09-06
7EW4 S1PR3 S1P3 Lysophospholipid (S1P) A (Rhodopsin) Human N/A 0 0 0 0 7EW4 3.2 10.1038/S41422-021-00567-W 2021-09-29
6OBA ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 1 2 0 1 6OBA 3.1 10.1038/S41589-020-0549-2 2020-03-25
7RTB GLP1R GLP-1 Glucagon B1 (Secretin) Human N/A 0 1 0 0 7RTB 2.1 10.1016/J.BBRC.2021.09.016 2021-10-06
7AUE MC4R MC4 Melanocortin A (Rhodopsin) Human N/A 0 0 0 0 7AUE 3.0 10.1126/SCIENCE.ABF7958 2021-04-28
6H7M ADRB1 β1 Adrenoceptors A (Rhodopsin) Wild turkey N/A 6 3 0 2 6H7M 2.8 10.1126/SCIENCE.AAU5595 2018-10-17
7CX2 PE2R2 EP2 Prostanoid A (Rhodopsin) Human N/A 0 0 0 0 7CX2 2.8 10.1126/SCIADV.ABF1268 2021-05-05
2Y00 ADRB1 β1 Adrenoceptors A (Rhodopsin) Wild turkey vapour diffusion 8 3 0 1 2Y00 2.5 10.1038/NATURE09746 2011-01-12
7MTS GRM2 mGlu2 Metabotropic glutamate C (Glutamate) Human N/A 0 1 0 0 7MTS 3.2 10.1038/S41586-021-03680-3 2021-07-07
6CM4 DRD2 D2 Dopamine A (Rhodopsin) Human in meso/LCP 3 2 0 5 6CM4 2.9 10.1038/NATURE25758 2018-03-14
2ZIY OPSD Rhodopsin Opsins A (Rhodopsin) Japanese flying squid vapour diffusion 1 2 0 0 2ZIY 3.7 10.1074/JBC.C800040200 2008-05-06
7RMG NK1R NK1 Tachykinin A (Rhodopsin) Human N/A 0 0 0 0 7RMG 3.0 10.1038/S41589-021-00890-8 2021-11-03
7JHJ Q3KSP2 BILF1 Unclassified A (Rhodopsin) strain GD1 N/A 0 0 0 0 7JHJ 3.2 10.1016/J.IMMUNI.2021.06.001 2021-07-07
7K15 LT4R1 BLT1 Leukotriene A (Rhodopsin) Human N/A 0 2 0 0 7K15 2.9 10.1038/S41467-021-23149-1 2021-02-17
7EW1 S1PR5 S1P5 Lysophospholipid (S1P) A (Rhodopsin) Human N/A 0 1 0 0 7EW1 3.4 10.1038/S41422-021-00566-X 2021-09-29
7F1Q CCR5 CCR5 Chemokine A (Rhodopsin) Human N/A 1 1 0 0 7F1Q 2.9 2021-07-14
7EZH CCKAR CCK1 Cholecystokinin A (Rhodopsin) Human N/A 0 0 0 0 7EZH 3.2 10.1038/S41589-021-00841-3 2021-08-25
6A93 5HT2A 5-HT2A 5-Hydroxytryptamine A (Rhodopsin) Human N/A 0 3 0 4 6A93 3.0 10.1038/S41594-018-0180-Z 2019-02-13
6W2X GABR2 GABAB2 GABAB C (Glutamate) Human N/A 0 1 0 0 6W2X 3.6 2020-07-01
6LW5 FPR2 FPR2/ALX Formylpeptide A (Rhodopsin) Human N/A 0 2 0 2 6LW5 2.8 10.1038/S41467-020-15009-1 2020-03-25
7SK6 ACKR3 ACKR3 Chemokine A (Rhodopsin) Human N/A 0 1 0 0 7SK6 4.0 10.1126/SCIADV.ABN8063 2022-07-27
7F9Y GHSR ghrelin Ghrelin A (Rhodopsin) Human N/A 0 0 0 0 7F9Y 2.9 10.1038/S41467-021-25364-2 2021-08-18
7F9Z GHSR ghrelin Ghrelin A (Rhodopsin) Human N/A 0 0 0 0 7F9Z 3.2 10.1038/S41467-021-25364-2 2021-08-18
7DUQ GLP1R GLP-1 Glucagon B1 (Secretin) Human N/A 0 1 0 0 7DUQ 2.5 10.1038/S41467-021-24058-Z 2021-07-14
7UM4 5HT5A 5-HT5A 5-Hydroxytryptamine A (Rhodopsin) Human N/A 0 1 0 0 7UM4 2.8 10.1038/S41594-022-00796-6 2022-07-20
7F8U CCKAR CCK1 Cholecystokinin A (Rhodopsin) Human N/A 0 3 0 0 7F8U 2.8 10.1038/S41589-021-00866-8 2021-10-13
3REY AA2AR A2A Adenosine A (Rhodopsin) Human vapour diffusion 8 1 0 1 3REY 3.3 10.1016/J.STR.2011.06.014 2011-09-07
4LDL ADRB2 β2 Adrenoceptors A (Rhodopsin) Human in meso/LCP 4 3 0 3 4LDL 3.1 10.1038/NATURE12572 2013-09-25
7BB7 V2R V2 Vasopressin and oxytocin A (Rhodopsin) Human N/A 0 1 0 0 7BB7 4.4 10.1126/SCIADV.ABG5628 2021-06-02
7T32 AA2AR A2A Adenosine A (Rhodopsin) Human N/A 0 3 0 0 7T32 3.4 10.1038/S41467-022-32125-2 2022-08-10
7FD8 GRM5 mGlu5 Metabotropic glutamate C (Glutamate) Human N/A 2 2 0 0 7FD8 3.8 10.1016/J.CELREP.2021.109648 2021-09-08
7PIV MC4R MC4 Melanocortin A (Rhodopsin) Human N/A 0 0 0 0 7PIV 2.9 10.1038/S41422-021-00569-8 2021-11-17
7RMI NK1R NK1 Tachykinin A (Rhodopsin) Human N/A 0 0 0 0 7RMI 3.2 10.1038/S41589-021-00890-8 2021-11-03
7E2Z 5HT1A 5-HT1A 5-Hydroxytryptamine A (Rhodopsin) Human N/A 0 1 0 0 7E2Z 3.1 10.1038/S41586-021-03376-8 2021-04-14
7E32 5HT1D 5-HT1D 5-Hydroxytryptamine A (Rhodopsin) Human N/A 0 1 0 0 7E32 2.9 10.1038/S41586-021-03376-8 2021-04-21
7DUR GLP1R GLP-1 Glucagon B1 (Secretin) Human N/A 0 1 0 0 7DUR 3.3 10.1038/S41467-021-24058-Z 2021-08-11
7E9H GRM4 mGlu4 Metabotropic glutamate C (Glutamate) Human N/A 0 1 0 0 7E9H 4.0 10.1038/S41586-021-03495-2 2021-06-23
7KI0 GLP1R GLP-1 Glucagon B1 (Secretin) Human N/A 0 1 0 0 7KI0 2.5 10.1016/J.CELREP.2021.109374 2021-08-04
7EVW FZD7 FZD7 Frizzled F (Frizzled) Human N/A 0 0 0 0 7EVW 3.2 10.1038/S41422-021-00525-6 2021-08-04
6WJC ACM1 M1 Acetylcholine (muscarinic) A (Rhodopsin) Human N/A 3 2 0 0 6WJC 2.6 10.1126/SCIENCE.AAX2517 2020-07-08
7S8L MRGX2 MRGPRX2 A orphans A (Rhodopsin) Human N/A 0 1 0 0 7S8L 2.5 10.1038/S41586-021-04126-6 2021-11-17
4U16 ACM3 M3 Acetylcholine (muscarinic) A (Rhodopsin) Rat sponge mesophase 0 3 0 4 4U16 3.7 10.1016/J.STR.2014.08.022 2014-11-26
7PP1 P2Y12 P2Y12 P2Y A (Rhodopsin) Human N/A 1 1 0 0 7PP1 2.8 10.1016/j.bcp.2022.115291 2022-11-02
7LD4 AA1R A1 Adenosine A (Rhodopsin) Human N/A 0 1 0 0 7LD4 3.3 10.1038/S41586-021-03897-2 2021-09-08
7SK4 ACKR3 ACKR3 Chemokine A (Rhodopsin) Human N/A 0 1 0 0 7SK4 3.3 10.1126/SCIADV.ABN8063 2022-07-27
8CXO SMO SMO Frizzled F (Frizzled) Mouse N/A 0 3 0 0 8CXO 3.7 10.1038/S41467-022-32125-2 2022-08-03
5WB1 Q80KM9 US28 Unclassified A (Rhodopsin) strain AD169 in meso/LCP 0 1 0 9 5WB1 3.5 10.7554/ELIFE.35850 2018-06-13
3P0G ADRB2 β2 Adrenoceptors A (Rhodopsin) Human in meso/LCP 3 2 0 3 3P0G 3.5 10.1038/NATURE09648 2011-01-19
7SK7 ACKR3 ACKR3 Chemokine A (Rhodopsin) Human N/A 0 1 0 0 7SK7 3.3 10.1126/SCIADV.ABN8063 2022-07-27
7EB2 GABR2 GABAB2 GABAB C (Glutamate) Human N/A 0 2 0 0 7EB2 3.5 10.1038/S41586-021-03507-1 2021-05-05
6JZH AA2AR A2A Adenosine A (Rhodopsin) Human N/A 0 3 0 3 6JZH 2.3 10.1107/S1600576719012846 2019-10-30
7E9G GRM2 mGlu2 Metabotropic glutamate C (Glutamate) Human N/A 0 2 0 0 7E9G 3.5 10.1038/S41586-021-03495-2 2021-06-23
7EZK CCKAR CCK1 Cholecystokinin A (Rhodopsin) Human N/A 0 0 0 0 7EZK 3.1 10.1038/S41589-021-00841-3 2021-08-25
7DH5 ADRB3 β3 Adrenoceptors A (Rhodopsin) Dog N/A 0 2 0 0 7DH5 3.2 10.1016/J.MOLCEL.2021.06.024 2021-08-04
7F2O BKRB2 B2 Bradykinin A (Rhodopsin) Human N/A 0 2 0 0 7F2O 2.9 10.1038/S41594-021-00645-Y 2021-10-13
4ZJC OX1R OX1 Orexin A (Rhodopsin) Human in meso/LCP 1 2 0 4 4ZJC 2.8 2016-03-09
7EIB BKRB1 B1 Bradykinin A (Rhodopsin) Human N/A 0 2 0 0 7EIB 3.0 10.1038/S41594-021-00645-Y 2021-10-13
7XW7 TSHR TSH Glycoprotein hormone A (Rhodopsin) Human N/A 0 2 0 0 7XW7 5.5 10.1038/S41586-022-05173-3 2022-08-17
5ZK8 ACM2 M2 Acetylcholine (muscarinic) A (Rhodopsin) Human N/A 0 2 0 5 5ZK8 3.0 10.1038/S41589-018-0152-Y 2018-11-21
7BB6 V2R V2 Vasopressin and oxytocin A (Rhodopsin) Human N/A 0 1 0 0 7BB6 4.2 10.1126/SCIADV.ABG5628 2021-06-02
4LDO ADRB2 β2 Adrenoceptors A (Rhodopsin) Human in meso/LCP 4 3 0 3 4LDO 3.2 10.1038/NATURE12572 2013-09-25
7FD9 GRM5 mGlu5 Metabotropic glutamate C (Glutamate) Human N/A 2 2 0 0 7FD9 4.0 10.1016/J.CELREP.2021.109648 2021-09-08
7DTY GIPR GIP Glucagon B1 (Secretin) Human N/A 0 1 0 0 7DTY 3.0 10.7554/ELIFE.68719 2021-08-04
7WC7 5HT2A 5-HT2A 5-Hydroxytryptamine A (Rhodopsin) Human N/A 0 3 0 0 7WC7 2.6 10.1126/SCIENCE.ABL8615 2022-01-26
7F53 MC4R MC4 Melanocortin A (Rhodopsin) Human N/A 0 0 0 0 7F53 3.0 2021-11-03
8DU3 AA2AR A2A Adenosine A (Rhodopsin) Human N/A 0 3 0 0 8DU3 2.5 10.1016/j.ejmech.2022.114620 2022-08-10
7MBX CCKAR CCK1 Cholecystokinin A (Rhodopsin) Human N/A 0 1 0 0 7MBX 2.0 10.1371/JOURNAL.PBIO.3001295 2021-05-26
5WF6 AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 1 3 0 4 5WF6 2.9 10.1016/J.STR.2017.12.013 2018-02-21
8IC0 CXCR1 CXCR1 Chemokine A (Rhodopsin) Human N/A 0 0 0 0 8IC0 3.4 10.1038/S41467-023-39799-2 2023-07-19
6J20 NK1R NK1 Tachykinin A (Rhodopsin) Human N/A 0 3 0 2 6J20 2.7 10.1038/S41467-019-08568-5 2019-03-06
7XRR OX2R OX2 Orexin A (Rhodopsin) Human N/A 0 3 0 0 7XRR 2.9 10.1016/J.STR.2022.11.001 2022-11-23
7VBI GLP1R GLP-1 Glucagon B1 (Secretin) Human N/A 0 1 0 0 7VBI 3.0 10.1038/S41467-022-28683-0 2022-03-02
7LLY GLP1R GLP-1 Glucagon B1 (Secretin) Human N/A 0 1 0 0 7LLY 3.3 10.1038/S41467-021-27760-0 2022-01-12
7T6V FPR2 FPR2/ALX Formylpeptide A (Rhodopsin) Human N/A 0 1 0 0 7T6V 3.1 10.1038/S41467-022-28586-0 2022-03-30
7F61 HRH3 H3 Histamine A (Rhodopsin) Human N/A 0 2 0 0 7F61 2.6 10.1038/S41467-022-33880-Y 2022-10-26
7SCG OPRM μ Opioid A (Rhodopsin) Mouse N/A 0 2 0 0 7SCG 3.0 10.1002/ANIE.202200269 2022-04-20
3RFM AA2AR A2A Adenosine A (Rhodopsin) Human vapour diffusion 8 1 0 2 3RFM 3.6 10.1016/J.STR.2011.06.014 2011-09-07
7VUZ MRGX2 MRGPRX2 A orphans A (Rhodopsin) Human N/A 0 0 0 0 7VUZ 2.9 10.1038/S41586-021-04077-Y 2021-12-01
8K5C HCAR2 HCA2 Hydroxycarboxylic acid A (Rhodopsin) Human N/A 0 0 0 0 8K5C 3.1 10.1038/S41467-023-42764-8 2023-11-22
7EW7 S1PR1 S1P1 Lysophospholipid (S1P) A (Rhodopsin) Human N/A 0 1 0 0 7EW7 3.3 10.1038/S41422-021-00566-X 2021-09-29
7RKF US28 US28 Unclassified A (Rhodopsin) strain AD169 N/A 0 0 0 0 7RKF 4.0 10.1126/SCIADV.ABL5442 2022-01-26
6UUN CALRL calcitonin-like Calcitonin B1 (Secretin) Human N/A 0 1 0 2 6UUN 3.0 10.1021/ACSPTSCI.9B00080 2020-03-25
7F4I MSHR MC1 Melanocortin A (Rhodopsin) Human N/A 0 1 0 0 7F4I 3.1 10.1038/S41422-021-00557-Y 2021-09-08
7SK9 ACKR3 ACKR3 Chemokine A (Rhodopsin) Human N/A 0 1 0 0 7SK9 3.7 10.1126/SCIADV.ABN8063 2022-07-27
6KP6 ACM4 M4 Acetylcholine (muscarinic) A (Rhodopsin) Human N/A 0 2 0 1 6KP6 3.0 10.1107/S2052252520000597 2020-03-11
7T6S FPR2 FPR2/ALX Formylpeptide A (Rhodopsin) Human N/A 0 1 0 0 7T6S 3.0 2022-03-30
7EJ8 ADA2A α2A Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 7EJ8 3.0 10.1126/SCIADV.ABJ5347 2022-04-13
7VLA CCR1 CCR1 Chemokine A (Rhodopsin) Human N/A 0 0 0 0 7VLA 2.7 10.1038/S41589-021-00918-Z 2022-03-23
7VUJ GP139 GPR139 A orphans A (Rhodopsin) Human N/A 0 2 0 0 7VUJ 3.8 10.1038/S41422-021-00591-W 2021-12-29
7TYN CALCR CT Calcitonin B1 (Secretin) Human N/A 0 1 0 0 7TYN 2.6 10.1126/SCIENCE.ABM9609 2022-03-30
4BEZ OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 3 0 0 0 4BEZ 3.3 10.1038/EMBOR.2013.44 2013-04-24
4XNW P2RY1 P2Y1 P2Y A (Rhodopsin) Human in meso/LCP 1 2 0 5 4XNW 2.7 10.1038/NATURE14287 2015-04-01
7W2Z GHSR ghrelin Ghrelin A (Rhodopsin) Human N/A 0 0 0 0 7W2Z 2.8 10.1038/S41467-022-27975-9 2022-01-19
7F4H MSHR MC1 Melanocortin A (Rhodopsin) Human N/A 0 1 0 0 7F4H 2.7 10.1038/S41422-021-00557-Y 2021-09-08
5U09 CNR1 CB1 Cannabinoid A (Rhodopsin) Human in meso/LCP 1 3 0 5 5U09 2.6 10.1038/NATURE20613 2016-12-07
6S0L AA2AR A2A Adenosine A (Rhodopsin) Human N/A 0 1 0 0 6S0L 2.7 10.1107/S2052252520011379 2020-07-15
7LLL GLP1R GLP-1 Glucagon B1 (Secretin) Human N/A 0 1 0 0 7LLL 3.7 10.1038/S41467-021-27760-0 2022-01-12
7WVU FPR1 FPR1 Formylpeptide A (Rhodopsin) Human N/A 0 2 0 0 7WVU 3.3 10.1038/S41467-022-29361-X 2022-04-13
6J21 NK1R NK1 Tachykinin A (Rhodopsin) Human N/A 0 3 0 2 6J21 3.2 10.1038/S41467-019-08568-5 2019-03-06
7EJA ADA2A α2A Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 7EJA 3.6 10.1126/SCIADV.ABJ5347 2022-04-13
7T6U FPR2 FPR2/ALX Formylpeptide A (Rhodopsin) Human N/A 0 1 0 0 7T6U 2.9 10.1038/S41467-022-28586-0 2022-03-30
7VL8 CCR1 CCR1 Chemokine A (Rhodopsin) Human N/A 0 0 0 0 7VL8 2.9 10.1038/S41589-021-00918-Z 2022-03-23
7SBF OPRM μ Opioid A (Rhodopsin) Mouse N/A 0 1 0 0 7SBF 2.9 10.1002/ANIE.202200269 2022-04-20
7WQ4 GALR2 GAL2 Galanin A (Rhodopsin) Human N/A 0 0 0 0 7WQ4 2.6 10.1038/S41467-022-29072-3 2022-04-20
7F4F MSHR MC1 Melanocortin A (Rhodopsin) Human N/A 0 1 0 0 7F4F 2.9 10.1038/S41422-021-00557-Y 2021-09-08
7WVX FPR2 FPR2/ALX Formylpeptide A (Rhodopsin) Human N/A 0 2 0 0 7WVX 2.8 10.1038/S41467-022-29361-X 2022-04-13
6ME4 MTR1A MT1 Melatonin A (Rhodopsin) Human N/A 0 3 0 2 6ME4 3.2 10.1038/S41586-019-1141-3 2019-04-24
7DD5 CASR CaS Calcium-sensing C (Glutamate) Human N/A 0 1 0 0 7DD5 3.2 10.1126/SCIADV.ABG1483 2021-06-16
7VGX NPY1R Y1 Neuropeptide Y A (Rhodopsin) Human N/A 0 0 0 0 7VGX 3.2 10.1038/S41467-022-28510-6 2022-02-23
7TD4 S1PR1 S1P1 Lysophospholipid (S1P) A (Rhodopsin) Human N/A 0 1 0 0 7TD4 2.6 10.1038/S41467-022-28417-2 2022-02-09
7EVZ S1PR1 S1P1 Lysophospholipid (S1P) A (Rhodopsin) Human N/A 0 1 0 0 7EVZ 3.1 10.1038/S41422-021-00566-X 2021-09-29
7F83 GHSR ghrelin Ghrelin A (Rhodopsin) Human N/A 0 3 0 0 7F83 2.9 10.1038/S41467-022-27975-9 2022-01-19
6KK1 GLP1R GLP-1 Glucagon B1 (Secretin) Human N/A 0 4 0 3 6KK1 2.8 2019-11-13
7VV5 MRGX2 MRGPRX2 A orphans A (Rhodopsin) Human N/A 0 0 0 0 7VV5 2.8 10.1038/S41586-021-04077-Y 2021-12-01
7VDH MRGX2 MRGPRX2 A orphans A (Rhodopsin) Human N/A 0 0 0 0 7VDH 2.9 10.1038/S41586-021-04077-Y 2021-12-01
5ZKB ACM2 M2 Acetylcholine (muscarinic) A (Rhodopsin) Human N/A 0 2 0 3 5ZKB 3.0 10.1038/S41589-018-0152-Y 2018-11-21
6IGK EDNRB ETB Endothelin A (Rhodopsin) Human N/A 0 3 0 1 6IGK 2.0 10.1038/S41467-018-07094-0 2018-11-21
7NA8 GHSR ghrelin Ghrelin A (Rhodopsin) Human N/A 0 0 0 0 7NA8 2.7 10.1038/S41467-021-26735-5 2021-12-15
7T6T FPR1 FPR1 Formylpeptide A (Rhodopsin) Human N/A 0 1 0 0 7T6T 3.2 10.1038/S41467-022-28586-0 2022-03-30
8JJL ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 1 3 0 0 8JJL 3.2 10.1038/S41589-023-01389-0 2023-09-06
7VH0 MTR1B MT2 Melatonin A (Rhodopsin) Human N/A 0 0 0 0 7VH0 3.5 10.1038/S41467-022-28111-3 2022-03-02
7FEE CNR1 CB1 Cannabinoid A (Rhodopsin) Human N/A 0 3 0 0 7FEE 2.7 10.1038/S41589-022-01038-Y 2022-06-15
7VUI GP139 GPR139 A orphans A (Rhodopsin) Human N/A 0 2 0 0 7VUI 3.3 10.1038/S41422-021-00591-W 2021-12-29
7TYF CALCR CT Calcitonin B1 (Secretin) Human N/A 0 1 0 0 7TYF 2.2 10.1126/SCIENCE.ABM9609 2022-03-23
7EJ0 ADA2A α2A Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 7EJ0 3.2 10.1126/SCIADV.ABJ5347 2022-04-13
6S0Q AA2AR A2A Adenosine A (Rhodopsin) Human N/A 0 3 0 0 6S0Q 2.7 10.1107/S2052252520011379 2020-07-15
7RKM US28 US28 Unclassified A (Rhodopsin) strain AD169 N/A 0 0 0 0 7RKM 3.5 10.1126/SCIADV.ABL5442 2022-01-26
7TD3 S1PR1 S1P1 Lysophospholipid (S1P) A (Rhodopsin) Human N/A 0 1 0 0 7TD3 3.0 10.1038/S41467-022-28417-2 2022-02-09
7T11 SSR2 SST2 Somatostatin A (Rhodopsin) Human N/A 0 1 0 0 7T11 2.7 10.1038/S41594-022-00727-5 2022-03-09
9D3E CCR6 CCR6 Chemokine A (Rhodopsin) Human N/A 0 0 0 0 9D3E 3.0 2024-09-11
7EVY S1PR1 S1P1 Lysophospholipid (S1P) A (Rhodopsin) Human N/A 0 1 0 0 7EVY 3.0 10.1038/S41422-021-00566-X 2021-09-29
7SRQ 5HT2B 5-HT2B 5-Hydroxytryptamine A (Rhodopsin) Human N/A 0 4 0 0 7SRQ 2.7 10.1016/J.NEURON.2022.08.006 2022-09-21
7WVW FPR2 FPR2/ALX Formylpeptide A (Rhodopsin) Human N/A 0 2 0 0 7WVW 3.1 10.1038/S41467-022-29361-X 2022-04-13
7V9M GHRHR GHRH Glucagon B1 (Secretin) Human N/A 0 1 0 0 7V9M 3.3 10.1073/PNAS.2106606118 2021-10-20
7FIY GIPR GIP Glucagon B1 (Secretin) Human N/A 0 2 0 0 7FIY 3.4 10.1038/S41467-022-28683-0 2022-03-02
7VGZ MTR1A MT1 Melatonin A (Rhodopsin) Human N/A 0 0 0 0 7VGZ 3.3 10.1038/S41467-022-28111-3 2022-03-02
6RZ5 CLTR1 CysLT1 Leukotriene A (Rhodopsin) Human N/A 0 1 0 4 6RZ5 2.5 10.1126/SCIADV.AAX2518 2019-10-30
7FIM GLP1R GLP-1 Glucagon B1 (Secretin) Human N/A 0 1 0 0 7FIM 3.4 10.1038/S41467-022-28683-0 2022-03-02
7VDL MRGX2 MRGPRX2 A orphans A (Rhodopsin) Human N/A 0 0 0 0 7VDL 3.2 10.1038/S41586-021-04077-Y 2021-12-01
7VUH GP139 GPR139 A orphans A (Rhodopsin) Human N/A 0 2 0 0 7VUH 3.2 2021-12-29
6RZ6 CLTR2 CysLT2 Leukotriene A (Rhodopsin) Human N/A 0 3 0 1 6RZ6 2.4 10.1038/S41467-019-13348-2 2019-12-11
7WVV FPR2 FPR2/ALX Formylpeptide A (Rhodopsin) Human N/A 0 2 0 0 7WVV 2.9 10.1038/S41467-022-29361-X 2022-04-13
7TYW CALCR CT Calcitonin B1 (Secretin) Human N/A 0 1 0 0 7TYW 3.0 10.1126/SCIENCE.ABM9609 2022-03-23
7VGY MTR1A MT1 Melatonin A (Rhodopsin) Human N/A 0 0 0 0 7VGY 3.1 10.1038/S41467-022-28111-3 2022-03-02
7VV3 MRGX2 MRGPRX2 A orphans A (Rhodopsin) Human N/A 0 0 0 0 7VV3 3.0 10.1038/S41586-021-04077-Y 2021-12-01
7T10 SSR2 SST2 Somatostatin A (Rhodopsin) Human N/A 0 1 0 0 7T10 2.5 10.1038/S41594-022-00727-5 2022-03-09
2RH1 ADRB2 β2 Adrenoceptors A (Rhodopsin) Human in meso/LCP 3 2 0 2 2RH1 2.4 10.1126/SCIENCE.1150577 2007-10-30
7EO2 S1PR1 S1P1 Lysophospholipid (S1P) A (Rhodopsin) Human N/A 0 1 0 0 7EO2 2.9 10.1038/S41589-021-00930-3 2022-01-05
6ME3 MTR1A MT1 Melatonin A (Rhodopsin) Human N/A 0 3 0 2 6ME3 2.9 10.1038/S41586-019-1141-3 2019-04-24
7S3I GLP1R GLP-1 Glucagon B1 (Secretin) Human N/A 0 1 0 0 7S3I 2.5 10.1038/S41589-021-00945-W 2022-01-05
7TYH CALCR CT Calcitonin B1 (Secretin) Human N/A 0 1 0 0 7TYH 3.3 10.1126/SCIENCE.ABM9609 2022-03-23
7VAB GIPR GIP Glucagon B1 (Secretin) Human N/A 0 2 0 0 7VAB 3.2 10.1038/S41467-022-28683-0 2022-03-02
7S8O MRGX2 MRGPRX2 A orphans A (Rhodopsin) Human N/A 0 1 0 0 7S8O 2.6 10.1038/S41586-021-04126-6 2021-11-17
7WF7 S1PR1 S1P1 Lysophospholipid (S1P) A (Rhodopsin) Human N/A 0 0 0 0 7WF7 3.4 10.1038/S41589-021-00930-3 2022-01-05
7VL9 CCR1 CCR1 Chemokine A (Rhodopsin) Human N/A 0 0 0 0 7VL9 2.6 10.1038/S41589-021-00918-Z 2022-03-23
7TYO CALCR CT Calcitonin B1 (Secretin) Human N/A 0 1 0 0 7TYO 2.7 10.1126/SCIENCE.ABM9609 2022-03-23
6UP7 NTR1 NTS1 Neurotensin A (Rhodopsin) Human N/A 0 2 0 0 6UP7 4.2 10.1038/S41586-020-1953-1 2020-02-26
6RZ8 CLTR2 CysLT2 Leukotriene A (Rhodopsin) Human N/A 0 3 0 1 6RZ8 2.7 10.1038/S41467-019-13348-2 2019-12-11
7V35 GLR glucagon Glucagon B1 (Secretin) Human N/A 0 2 0 0 7V35 3.4 10.1038/S41467-022-28683-0 2022-03-02
7SF8 AGRG1 ADGRG1 ADGRG B2 (Adhesion) Human N/A 0 2 0 0 7SF8 2.7 10.1038/S41586-022-04575-7 2022-04-27
7W0P APJ apelin Apelin A (Rhodopsin) Human N/A 0 2 0 0 7W0P 3.2 10.1038/S41594-022-00797-5 2022-07-27
5XJM AGTR2 AT2 Angiotensin A (Rhodopsin) Human N/A 0 3 0 3 5XJM 3.2 10.1038/S41594-018-0079-8 2018-07-11
9IZH LPAR1 LPA1 Lysophospholipid (LPA) A (Rhodopsin) Human N/A 0 1 0 0 9IZH 3.0 10.1016/J.JSB.2024.108164 2025-01-01
4MQS ACM2 M2 Acetylcholine (muscarinic) A (Rhodopsin) Human in meso/LCP 6 1 0 3 4MQS 3.5 10.1038/NATURE12735 2013-11-27
8X63 HRH1 H1 Histamine A (Rhodopsin) Human N/A 0 3 0 0 8X63 3.2 10.1038/S41467-023-44477-4 2024-01-17
5ZKC ACM2 M2 Acetylcholine (muscarinic) A (Rhodopsin) Human N/A 0 2 0 5 5ZKC 2.3 10.1038/S41589-018-0152-Y 2018-11-21
7XOW GASR CCK2 Cholecystokinin A (Rhodopsin) Human N/A 0 0 0 0 7XOW 3.1 10.1038/S41421-022-00420-3 2022-07-20
7WIC SSR2 SST2 Somatostatin A (Rhodopsin) Human N/A 0 0 0 0 7WIC 2.8 10.1038/S41422-022-00669-Z 2022-06-01
7SF7 AGRL3 ADGRL3 ADGRL B2 (Adhesion) Human N/A 0 1 0 0 7SF7 2.9 10.1038/S41586-022-04575-7 2022-04-27
8K5B HCAR2 HCA2 Hydroxycarboxylic acid A (Rhodopsin) Human N/A 0 0 0 0 8K5B 3.4 10.1038/S41467-023-42764-8 2023-11-22
7X9B NPY2R Y2 Neuropeptide Y A (Rhodopsin) Human N/A 0 1 0 0 7X9B 3.4 10.1126/SCIADV.ABM1232 2022-05-18
7P2L GRM5 mGlu5 Metabotropic glutamate C (Glutamate) Human N/A 6 2 0 0 7P2L 2.5 10.1016/J.CELREP.2021.109648 2021-09-08
7UM6 5HT5A 5-HT5A 5-Hydroxytryptamine A (Rhodopsin) Human N/A 0 1 0 0 7UM6 2.8 10.1038/S41594-022-00796-6 2022-07-20
7XOX GASR CCK2 Cholecystokinin A (Rhodopsin) Human N/A 0 0 0 0 7XOX 3.1 10.1038/S41421-022-00420-3 2022-07-20
8JJO ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 3 0 0 8JJO 3.4 10.1038/S41589-023-01389-0 2023-09-06
7XT9 5HT4R 5-HT4 5-Hydroxytryptamine A (Rhodopsin) Human N/A 0 1 0 0 7XT9 3.2 10.1016/J.MOLCEL.2022.05.031 2022-07-27
7XJK GALR2 GAL2 Galanin A (Rhodopsin) Human N/A 0 1 0 0 7XJK 3.3 10.1073/PNAS.2121465119 2022-06-29
7F1O DRD1 D1 Dopamine A (Rhodopsin) Human N/A 0 0 0 0 7F1O 3.1 10.1126/SCIADV.ABO4158 2022-06-15
7X2F DRD1 D1 Dopamine A (Rhodopsin) Human N/A 0 0 0 0 7X2F 3.0 10.1038/S41467-022-30929-W 2022-06-15
7F6H BKRB2 B2 Bradykinin A (Rhodopsin) Human N/A 0 0 0 0 7F6H 2.9 10.1038/S41467-022-28399-1 2022-01-05
7W0O APJ apelin Apelin A (Rhodopsin) Human N/A 0 2 0 0 7W0O 3.8 10.1038/S41594-022-00797-5 2022-07-27
8JMT AGRL3 ADGRL3 ADGRL B2 (Adhesion) Human N/A 0 1 0 0 8JMT 3.3 10.1038/S41589-023-01389-0 2023-09-06
7EPT AGRD1 ADGRD1 ADGRD B2 (Adhesion) Human N/A 0 2 0 0 7EPT 3.0 10.1038/S41586-022-04619-Y 2022-05-11
7T6B S1PR2 S1P2 Lysophospholipid (S1P) A (Rhodopsin) Human N/A 0 0 0 0 7T6B 3.2 10.1126/SCIADV.ABN0067 2022-04-06
9DQH MRGRD MRGPRD A orphans A (Rhodopsin) Human N/A 0 1 0 0 9DQH 2.9 2024-12-11
6LUQ DRD2 D2 Dopamine A (Rhodopsin) Human N/A 0 2 0 1 6LUQ 3.1 10.1038/S41467-020-14884-Y 2020-03-04
9IZG LPAR1 LPA1 Lysophospholipid (LPA) A (Rhodopsin) Human N/A 0 1 0 0 9IZG 3.0 2025-01-01
8T1W GPR6 GPR6 A orphans A (Rhodopsin) Human N/A 0 2 0 0 8T1W 3.5 10.1126/SCISIGNAL.ADO8741 2024-12-04
9IJA T2R14 TAS2R14 Taste 2 T2 (Taste 2) Human N/A 0 0 0 0 9IJA 3.1 2024-07-24
6RZ9 CLTR2 CysLT2 Leukotriene A (Rhodopsin) Human N/A 0 3 0 1 6RZ9 2.7 10.1038/S41467-019-13348-2 2019-12-11
9IYA GPR55 GPR55 GPR18, GPR55 and GPR119 A (Rhodopsin) Human N/A 0 2 0 0 9IYA 3.0 2025-01-01
5NJ6 PAR2 PAR2 Proteinase-activated A (Rhodopsin) Human in meso/LCP 10 3 0 2 5NJ6 4.0 10.1038/NATURE22309 2017-05-03
7WUQ AGRG2 ADGRG2 ADGRG B2 (Adhesion) Mouse N/A 0 1 0 0 7WUQ 2.9 10.1038/S41586-022-04590-8 2022-04-27
3PBL DRD3 D3 Dopamine A (Rhodopsin) Human in meso/LCP 1 2 0 5 3PBL 2.9 10.1126/SCIENCE.1197410 2010-11-03
7WU5 AGRF1 ADGRF1 ADGRF B2 (Adhesion) Human N/A 0 2 0 0 7WU5 3.0 10.1038/S41586-022-04580-W 2022-04-27
2J4Y OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 2 0 0 0 2J4Y 3.4 10.1016/J.JMB.2007.03.007 2007-09-25
4MQT ACM2 M2 Acetylcholine (muscarinic) A (Rhodopsin) Human in meso/LCP 6 1 0 3 4MQT 3.7 2013-11-27
7X8S GLP1R GLP-1 Glucagon B1 (Secretin) Human N/A 0 1 0 0 7X8S 3.1 10.1073/PNAS.2200155119 2022-06-29
6FFH GRM5 mGlu5 Metabotropic glutamate C (Glutamate) Human in meso/LCP 6 2 0 3 6FFH 2.7 10.1021/ACS.JMEDCHEM.7B01722 2018-03-07
3ODU CXCR4 CXCR4 Chemokine A (Rhodopsin) Human in meso/LCP 1 2 0 7 3ODU 2.5 2010-10-27
6D26 PD2R2 DP2 Prostanoid A (Rhodopsin) Human N/A 0 2 0 5 6D26 2.8 10.1016/J.MOLCEL.2018.08.009 2018-10-03
7S0G ADRB1 β1 Adrenoceptors A (Rhodopsin) Wild turkey N/A 0 1 0 0 7S0G 3.9 10.1038/S41594-021-00679-2 2021-11-17
7W55 NMUR2 NMU2 Neuromedin U A (Rhodopsin) Human N/A 0 1 0 0 7W55 2.8 10.1038/S41467-022-29683-W 2022-04-20
7W0L APJ apelin Apelin A (Rhodopsin) Human N/A 0 2 0 0 7W0L 3.6 10.1038/S41594-022-00797-5 2022-07-27
7XJL GALR2 GAL2 Galanin A (Rhodopsin) Human N/A 0 1 0 0 7XJL 3.5 10.1073/PNAS.2121465119 2022-06-29
7X9A NPY1R Y1 Neuropeptide Y A (Rhodopsin) Human N/A 0 1 0 0 7X9A 3.2 10.1126/SCIADV.ABM1232 2022-05-18
9CHV ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 1 3 0 0 9CHV 4.0 10.1073/PNAS.2414544121 2024-11-13
8X5X HRH1 H1 Histamine A (Rhodopsin) Human N/A 0 3 0 0 8X5X 3.5 10.1038/S41467-023-44477-4 2024-01-17
6KJV GLP1R GLP-1 Glucagon B1 (Secretin) Human N/A 0 4 0 3 6KJV 2.8 10.1107/S2052252519013496 2019-11-13
7WBJ VIPR2 VPAC2 VIP and PACAP B1 (Secretin) Human N/A 0 1 0 0 7WBJ 3.4 10.1038/S41467-022-30041-Z 2022-05-18
7RGP GLP1R GLP-1 Glucagon B1 (Secretin) Human N/A 0 2 0 0 7RGP 2.9 10.1073/PNAS.2116506119 2022-04-13
7XT8 5HT4R 5-HT4 5-Hydroxytryptamine A (Rhodopsin) Human N/A 0 1 0 0 7XT8 3.1 10.1016/J.MOLCEL.2022.05.031 2022-07-27
7WKD TRFR TRH1 Thyrotropin-releasing hormone A (Rhodopsin) Human N/A 0 0 0 0 7WKD 3.0 10.1038/S41422-022-00641-X 2022-06-15
7X2D DRD1 D1 Dopamine A (Rhodopsin) Human N/A 0 0 0 0 7X2D 3.3 10.1038/S41467-022-30929-W 2022-06-15
7SQO OX2R OX2 Orexin A (Rhodopsin) Human N/A 0 0 0 0 7SQO 3.2 10.1038/S41467-022-30601-3 2022-05-25
7DD6 CASR CaS Calcium-sensing C (Glutamate) Human N/A 0 1 0 0 7DD6 3.2 10.1126/SCIADV.ABG1483 2021-06-16
5UZ7 CALCR CT Calcitonin B1 (Secretin) Human Cryo-EM 0 1 0 5 5UZ7 4.1 10.1038/NATURE22327 2017-05-03
7UM7 5HT5A 5-HT5A 5-Hydroxytryptamine A (Rhodopsin) Human N/A 0 1 0 0 7UM7 2.8 10.1038/S41594-022-00796-6 2022-07-20
7S0F ADRB1 β1 Adrenoceptors A (Rhodopsin) Wild turkey N/A 0 1 0 0 7S0F 3.0 10.1038/S41594-021-00679-2 2021-11-17
7F24 DRD1 D1 Dopamine A (Rhodopsin) Human N/A 0 0 0 0 7F24 4.2 10.1126/SCIADV.ABO4158 2022-06-15
7WU2 AGRD1 ADGRD1 ADGRD B2 (Adhesion) Human N/A 0 2 0 0 7WU2 2.8 10.1038/S41586-022-04580-W 2022-04-27
7W0N APJ apelin Apelin A (Rhodopsin) Human N/A 0 2 0 0 7W0N 4.2 10.1038/S41594-022-00797-5 2022-07-27
8T6J GRM5 mGlu5 Metabotropic glutamate C (Glutamate) Human N/A 0 2 0 0 8T6J 3.5 10.1101/2023.08.29.555158 2023-10-11
9IY8 GPR55 GPR55 GPR18, GPR55 and GPR119 A (Rhodopsin) Human N/A 0 1 0 0 9IY8 3.0 10.1038/S41422-024-01046-8 2025-01-01
7X2C DRD1 D1 Dopamine A (Rhodopsin) Human N/A 0 0 0 0 7X2C 3.2 10.1038/S41467-022-30929-W 2022-06-29
7XJI ADRB3 β3 Adrenoceptors A (Rhodopsin) Dog N/A 0 2 0 0 7XJI 3.9 10.1016/J.BBRC.2022.04.065 2022-05-04
7EQ1 AGRG5 ADGRG5 ADGRG B2 (Adhesion) Human N/A 0 1 0 0 7EQ1 3.3 10.1038/S41586-022-04619-Y 2022-05-11
7F23 DRD1 D1 Dopamine A (Rhodopsin) Human N/A 0 0 0 0 7F23 3.6 10.1126/SCIADV.ABO4158 2022-06-15
7RBT GIPR GIP Glucagon B1 (Secretin) Human N/A 0 1 0 0 7RBT 3.1 10.1073/PNAS.2116506119 2022-04-13
7VBH GLP1R GLP-1 Glucagon B1 (Secretin) Human N/A 0 1 0 0 7VBH 3.0 10.1038/S41467-022-28683-0 2022-04-06
8T7H GRM5 mGlu5 Metabotropic glutamate C (Glutamate) Human N/A 0 2 0 0 8T7H 3.3 10.1101/2023.08.29.555158 2023-10-11
9IVG GLP1R GLP-1 Glucagon B1 (Secretin) Human N/A 0 1 0 0 9IVG 3.0 10.1016/J.APSB.2024.09.002 2024-11-27
6FJ3 PTH1R PTH1 Parathyroid hormone B1 (Secretin) Human N/A 0 4 0 2 6FJ3 2.5 10.1038/S41594-018-0151-4 2018-11-21
7XTC 5HT7R 5-HT7 5-Hydroxytryptamine A (Rhodopsin) Human N/A 0 2 0 0 7XTC 3.2 10.1016/J.MOLCEL.2022.05.031 2022-07-27
7XBD GALR2 GAL2 Galanin A (Rhodopsin) Human N/A 0 0 0 0 7XBD 3.1 10.1371/JOURNAL.PBIO.3001714 2022-07-13
9IVM GLP1R GLP-1 Glucagon B1 (Secretin) Human N/A 0 1 0 0 9IVM 3.2 2024-11-13
6RZ7 CLTR2 CysLT2 Leukotriene A (Rhodopsin) Human N/A 0 3 0 1 6RZ7 2.4 10.1038/S41467-019-13348-2 2019-12-11
8T1V GPR6 GPR6 A orphans A (Rhodopsin) Human N/A 0 2 0 0 8T1V 2.6 10.1126/SCISIGNAL.ADO8741 2024-12-04
8X5Y HRH1 H1 Histamine A (Rhodopsin) Human N/A 0 3 0 0 8X5Y 3.0 10.1038/S41467-023-44477-4 2024-01-17
7RA3 GIPR GIP Glucagon B1 (Secretin) Human N/A 0 1 0 0 7RA3 3.2 10.1073/PNAS.2116506119 2022-04-13
7XTB 5HT6R 5-HT6 5-Hydroxytryptamine A (Rhodopsin) Human N/A 0 1 0 0 7XTB 3.3 10.1016/J.MOLCEL.2022.05.031 2022-07-27
7XOU CCKAR CCK1 Cholecystokinin A (Rhodopsin) Human N/A 0 0 0 0 7XOU 3.2 10.1038/S41421-022-00420-3 2022-07-20
7U2L OPRM μ Opioid A (Rhodopsin) Mouse N/A 0 2 0 0 7U2L 3.2 10.1038/S41586-022-05588-Y 2022-05-04
7WU4 AGRF1 ADGRF1 ADGRF B2 (Adhesion) Human N/A 0 2 0 0 7WU4 3.4 10.1038/S41586-022-04580-W 2022-04-27
7TUZ GP183 GPR183 A orphans A (Rhodopsin) Human N/A 0 1 0 0 7TUZ 3.1 10.1016/J.STR.2022.04.006 2022-04-13
7W56 NMUR1 NMU1 Neuromedin U A (Rhodopsin) Human N/A 0 1 0 0 7W56 2.9 10.1038/S41467-022-29683-W 2022-04-20
7W53 NMUR1 NMU1 Neuromedin U A (Rhodopsin) Human N/A 0 1 0 0 7W53 3.2 10.1038/S41467-022-29683-W 2022-04-20
7T9N TSHR TSH Glycoprotein hormone A (Rhodopsin) Human N/A 0 1 0 0 7T9N 2.9 10.1038/S41586-022-05159-1 2022-08-03
7VV4 MRGX2 MRGPRX2 A orphans A (Rhodopsin) Human N/A 0 0 0 0 7VV4 3.0 10.1038/S41586-021-04077-Y 2021-12-01
7XKF AGRG2 ADGRG2 ADGRG B2 (Adhesion) Mouse N/A 0 2 0 0 7XKF 2.4 10.1038/S41589-022-01084-6 2022-08-10
7RM5 AA2AR A2A Adenosine A (Rhodopsin) Human N/A 0 3 0 0 7RM5 2.8 10.1073/PNAS.2106041118 2021-09-08
7X9Y CCR3 CCR3 Chemokine A (Rhodopsin) Human N/A 0 0 0 0 7X9Y 3.1 10.1038/S41421-022-00403-4 2022-08-24
7XMT SSR4 SST4 Somatostatin A (Rhodopsin) Human N/A 0 2 0 0 7XMT 2.8 10.1038/S41422-022-00679-X 2022-08-03
7QVM OXYR OT Vasopressin and oxytocin A (Rhodopsin) Human N/A 0 1 0 0 7QVM 3.3 10.1038/S41467-022-31325-0 2022-08-10
7X2V AGRF1 ADGRF1 ADGRF B2 (Adhesion) Human N/A 0 0 0 0 7X2V 3.1 10.1038/S41467-022-33173-4 2022-09-28
7ZBC OPSD Rhodopsin Opsins A (Rhodopsin) Bovine N/A 0 0 0 0 7ZBC 1.8 10.1038/S41586-023-05863-6 2023-03-29
7VVJ PTH1R PTH1 Parathyroid hormone B1 (Secretin) Human N/A 0 2 0 0 7VVJ 3.2 10.1016/J.MOLCEL.2022.07.003 2022-08-03
7VIE S1PR1 S1P1 Lysophospholipid (S1P) A (Rhodopsin) Human N/A 0 0 0 0 7VIE 2.9 10.1073/PNAS.2117716119 2022-09-28
7SRR 5HT2B 5-HT2B 5-Hydroxytryptamine A (Rhodopsin) Human N/A 0 2 0 0 7SRR 2.9 10.1016/J.NEURON.2022.08.006 2022-09-21
8W77 O52E4 OR52E4 Odorant family 52 O1 (fish-like odorant) Human N/A 0 1 0 0 8W77 3.6 10.1038/S41467-023-43983-9 2023-12-20
7VIF S1PR1 S1P1 Lysophospholipid (S1P) A (Rhodopsin) Human N/A 0 0 0 0 7VIF 2.8 10.1073/PNAS.2117716119 2022-09-28
7R0C V2R V2 Vasopressin and oxytocin A (Rhodopsin) Human N/A 0 1 0 0 7R0C 4.7 10.1126/SCIADV.ABO7761 2022-09-14
7XMS SSR4 SST4 Somatostatin A (Rhodopsin) Human N/A 0 2 0 0 7XMS 2.9 10.1038/S41422-022-00679-X 2022-08-03
7VIH S1PR1 S1P1 Lysophospholipid (S1P) A (Rhodopsin) Human N/A 0 0 0 0 7VIH 3.0 10.1073/PNAS.2117716119 2022-09-28
6DRY 5HT2B 5-HT2B 5-Hydroxytryptamine A (Rhodopsin) Human N/A 1 3 0 2 6DRY 2.9 10.1038/s41594-018-0116-7 2018-08-29
7XTQ GPBAR GPBA Bile acid A (Rhodopsin) Human N/A 0 0 0 0 7XTQ 3.2 10.1073/PNAS.2117054119 2022-07-06
6LPK AA2AR A2A Adenosine A (Rhodopsin) Human N/A 0 3 0 0 6LPK 1.8 2020-11-25
8GNG AA2AR A2A Adenosine A (Rhodopsin) Human N/A 0 1 0 0 8GNG 3.2 10.1124/MOLPHARM.122.000633 2023-03-22
4Z9G CRFR1 CRF1 Corticotropin-releasing factor B1 (Secretin) Human in meso/LCP 11 3 0 3 4Z9G 3.2 10.2174/1874467210666170110114727 2016-06-29
8TB7 GPR61 GPR61 A orphans A (Rhodopsin) Human N/A 0 2 0 0 8TB7 2.9 10.1038/S41467-023-41646-3 2023-10-04
7XN9 SSR2 SST2 Somatostatin A (Rhodopsin) Human N/A 0 3 0 0 7XN9 2.6 10.1038/S41422-022-00679-X 2022-08-03
8A6E OPSD Rhodopsin Opsins A (Rhodopsin) Bovine N/A 0 0 0 0 8A6E 1.8 10.1038/S41586-023-05863-6 2023-03-29
7WY5 AGRL3 ADGRL3 ADGRL B2 (Adhesion) Mouse N/A 0 0 0 0 7WY5 2.8 10.1016/J.MOLCEL.2022.10.009 2022-10-26
6IGL EDNRB ETB Endothelin A (Rhodopsin) Human N/A 0 3 0 1 6IGL 2.7 10.1038/S41467-018-07094-0 2018-11-21
7XMR SSR2 SST2 Somatostatin A (Rhodopsin) Human N/A 0 2 0 0 7XMR 3.1 10.1038/S41422-022-00679-X 2022-08-03
4YAY AGTR1 AT1 Angiotensin A (Rhodopsin) Human in meso/LCP 0 3 0 5 4YAY 2.9 10.1016/J.CELL.2015.04.011 2015-04-22
8DCS ADRB1 β1 Adrenoceptors A (Rhodopsin) Wild turkey N/A 0 1 0 0 8DCS 2.5 10.1038/S41467-022-31823-1 2022-07-27
7WXW AGRF1 ADGRF1 ADGRF B2 (Adhesion) Human N/A 0 0 0 0 7WXW 2.8 10.1038/S41467-022-33173-4 2022-09-28
7YP7 AGRG2 ADGRG2 ADGRG B2 (Adhesion) Mouse N/A 0 2 0 0 7YP7 3.1 2022-08-24
8GED ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8GED 3.5 10.1038/S41586-024-07153-1 2024-03-06
7WJ5 SSR2 SST2 Somatostatin A (Rhodopsin) Human N/A 0 0 0 0 7WJ5 3.7 10.7554/ELIFE.76823 2022-07-13
8A6D OPSD Rhodopsin Opsins A (Rhodopsin) Bovine N/A 0 0 0 0 8A6D 1.8 10.1038/S41586-023-05863-6 2023-03-29
7XP5 T2R46 TAS2R46 Taste 2 T2 (Taste 2) Human N/A 0 1 0 0 7XP5 3.1 10.1126/SCIENCE.ABO1633 2022-10-12
7XAV SSR2 SST2 Somatostatin A (Rhodopsin) Human N/A 0 1 0 0 7XAV 2.9 10.1038/S41421-022-00405-2 2022-08-31
5VEX GLP1R GLP-1 Glucagon B1 (Secretin) Human in meso/LCP 10 4 0 5 5VEX 3.0 10.1038/NATURE22378 2017-05-17
5V56 SMO SMO Frizzled F (Frizzled) Human in meso/LCP 1 3 0 6 5V56 2.9 10.1038/NCOMMS15383 2017-05-24
7W6P ADA2A α2A Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 7W6P 3.5 10.1126/SCIENCE.ABN7065 2022-09-28
8XBI GPR34 GPR34 A orphans A (Rhodopsin) Human N/A 0 1 0 0 8XBI 3.1 2023-12-27
7VVK PTH1R PTH1 Parathyroid hormone B1 (Secretin) Human N/A 0 2 0 0 7VVK 3.3 10.1016/J.MOLCEL.2022.07.003 2022-08-03
7WY8 AGRL3 ADGRL3 ADGRL B2 (Adhesion) Mouse N/A 0 0 0 0 7WY8 2.8 10.1016/J.MOLCEL.2022.10.009 2022-10-26
7VVO PTH1R PTH1 Parathyroid hormone B1 (Secretin) Human N/A 0 2 0 0 7VVO 4.1 10.1016/J.MOLCEL.2022.07.003 2022-08-03
7X1T TRFR TRH1 Thyrotropin-releasing hormone A (Rhodopsin) Human N/A 0 0 0 0 7X1T 3.3 10.1038/S41422-022-00646-6 2022-08-31
6UVA CALRL calcitonin-like Calcitonin B1 (Secretin) Human N/A 0 1 0 2 6UVA 2.3 10.1021/ACSPTSCI.9B00080 2020-04-01
7VFX FPR1 FPR1 Formylpeptide A (Rhodopsin) Human N/A 0 0 0 0 7VFX 2.8 10.1038/S41467-022-32822-Y 2022-09-21
7X1U TRFR TRH1 Thyrotropin-releasing hormone A (Rhodopsin) Human N/A 0 0 0 0 7X1U 3.2 2022-08-31
7XBX CX3C1 CX3CR1 Chemokine A (Rhodopsin) Human N/A 0 1 0 0 7XBX 3.4 2022-07-13
6ZFZ ACM1 M1 Acetylcholine (muscarinic) A (Rhodopsin) Human N/A 0 3 0 0 6ZFZ 2.2 10.1016/J.CELL.2021.11.001 2021-10-06
7WCM GP119 GPR119 GPR18, GPR55 and GPR119 A (Rhodopsin) Human N/A 0 0 0 0 7WCM 2.3 10.1038/S41467-022-34696-6 2022-12-21
7WU9 PE2R3 EP3 Prostanoid A (Rhodopsin) Human N/A 0 2 0 0 7WU9 3.4 10.1016/J.CELREP.2022.111323 2022-08-17
7YOO NPY2R Y2 Neuropeptide Y A (Rhodopsin) Human N/A 0 1 0 0 7YOO 3.1 10.1016/J.STR.2022.11.010 2023-03-22
7XKD AGRG2 ADGRG2 ADGRG B2 (Adhesion) Mouse N/A 0 2 0 0 7XKD 2.4 10.1038/S41589-022-01084-6 2022-08-10
6ME6 MTR1B MT2 Melatonin A (Rhodopsin) Human N/A 0 3 0 3 6ME6 2.8 10.1038/S41586-019-1144-0 2019-04-24
6TO7 OX1R OX1 Orexin A (Rhodopsin) Human N/A 0 3 0 2 6TO7 2.3 10.1021/acs.jmedchem.9b01787 2020-01-01
8DPH 5HT2C 5-HT2C 5-Hydroxytryptamine A (Rhodopsin) Human N/A 0 0 0 0 8DPH 3.2 10.1016/J.CELREP.2022.111211 2022-08-24
2Y02 ADRB1 β1 Adrenoceptors A (Rhodopsin) Wild turkey vapour diffusion 8 3 0 1 2Y02 2.6 2011-01-12
6UUS CALRL calcitonin-like Calcitonin B1 (Secretin) Human N/A 0 1 0 2 6UUS 2.4 10.1021/ACSPTSCI.9B00080 2020-04-01
7WCN GP119 GPR119 GPR18, GPR55 and GPR119 A (Rhodopsin) Human N/A 0 0 0 0 7WCN 2.9 10.1038/S41467-022-34696-6 2022-12-21
7DD7 CASR CaS Calcium-sensing C (Glutamate) Human N/A 0 1 0 0 7DD7 3.2 10.1126/SCIADV.ABG1483 2021-06-16
7VVM PTH1R PTH1 Parathyroid hormone B1 (Secretin) Human N/A 0 2 0 0 7VVM 3.2 10.1016/J.MOLCEL.2022.07.003 2022-08-03
7WYB AGRL3 ADGRL3 ADGRL B2 (Adhesion) Mouse N/A 0 0 0 0 7WYB 3.0 10.1016/J.MOLCEL.2022.10.009 2022-10-26
7SRS 5HT2B 5-HT2B 5-Hydroxytryptamine A (Rhodopsin) Human N/A 0 1 0 0 7SRS 3.3 10.1016/J.NEURON.2022.08.006 2022-09-21
7KNT CALRL calcitonin-like Calcitonin B1 (Secretin) Human N/A 0 1 0 0 7KNT 3.2 10.1126/SCIENCE.ABF7258 2021-02-24
7T2H OPRM μ Opioid A (Rhodopsin) Mouse N/A 0 2 0 0 7T2H 3.2 10.1038/S41589-022-01208-Y 2022-12-07
7X10 AGRL3 ADGRL3 ADGRL B2 (Adhesion) Mouse N/A 0 0 0 0 7X10 2.9 10.1016/J.MOLCEL.2022.10.009 2022-11-09
6PRZ ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 1 2 0 2 6PRZ 2.8 10.1107/S2052252519013137 2019-11-13
7XW5 TSHR TSH Glycoprotein hormone A (Rhodopsin) Human N/A 0 2 0 0 7XW5 3.0 10.1038/S41586-022-05173-3 2022-08-24
7DGD GRM1 mGlu1 Metabotropic glutamate C (Glutamate) Human N/A 0 2 0 0 7DGD 4.0 10.1007/S13238-020-00808-5 2021-09-22
8A6C OPSD Rhodopsin Opsins A (Rhodopsin) Bovine N/A 0 0 0 0 8A6C 1.8 10.1038/S41586-023-05863-6 2023-03-29
7WY0 AGRF1 ADGRF1 ADGRF B2 (Adhesion) Human N/A 0 0 0 0 7WY0 2.8 10.1038/S41467-022-33173-4 2022-09-28
8DCR ADRB1 β1 Adrenoceptors A (Rhodopsin) Wild turkey N/A 0 1 0 0 8DCR 2.6 10.1038/S41467-022-31823-1 2022-07-27
7TS0 CRFR2 CRF2 Corticotropin-releasing factor B1 (Secretin) Human N/A 0 2 0 0 7TS0 2.8 10.1038/S41467-022-33851-3 2022-11-09
7WZ7 AGRF1 ADGRF1 ADGRF B2 (Adhesion) Human N/A 0 0 0 0 7WZ7 2.8 10.1038/S41467-022-33173-4 2022-09-28
7UTZ TSHR TSH Glycoprotein hormone A (Rhodopsin) Human N/A 0 1 0 0 7UTZ 2.4 10.1038/S41586-022-05159-1 2022-08-03
7F1T CCR5 CCR5 Chemokine A (Rhodopsin) Human N/A 4 1 0 0 7F1T 2.6 2021-07-14
7VIG S1PR1 S1P1 Lysophospholipid (S1P) A (Rhodopsin) Human N/A 0 0 0 0 7VIG 2.9 10.1073/PNAS.2117716119 2022-09-28
3VG9 AA2AR A2A Adenosine A (Rhodopsin) Human vapour diffusion 1 1 0 3 3VG9 2.7 10.1038/NATURE10750 2012-02-01
7Y24 SSR2 SST2 Somatostatin A (Rhodopsin) Human N/A 0 1 0 0 7Y24 3.3 10.1038/S41589-022-01130-3 2022-10-19
7BR3 GNRHR GnRH1 Gonadotrophin-releasing hormone A (Rhodopsin) Human N/A 0 1 0 0 7BR3 2.8 10.1038/S41467-020-19109-W 2020-10-07
8EA0 ACM3 M3 Acetylcholine (muscarinic) A (Rhodopsin) Human N/A 0 2 0 0 8EA0 2.6 10.1038/S41586-022-05489-0 2022-11-30
7XZ5 GP119 GPR119 GPR18, GPR55 and GPR119 A (Rhodopsin) Human N/A 0 0 0 0 7XZ5 3.1 10.1038/S41594-022-00816-5 2022-08-24
7WZ4 GPR88 GPR88 A orphans A (Rhodopsin) Human N/A 0 0 0 0 7WZ4 3.0 10.1038/S41467-022-30081-5 2022-10-26
8DPG 5HT2C 5-HT2C 5-Hydroxytryptamine A (Rhodopsin) Human N/A 0 0 0 0 8DPG 3.6 10.1016/J.CELREP.2022.111211 2022-08-24
6ME8 MTR1B MT2 Melatonin A (Rhodopsin) Human N/A 0 3 0 3 6ME8 3.1 10.1038/S41586-019-1144-0 2019-04-24
7XAU SSR2 SST2 Somatostatin A (Rhodopsin) Human N/A 0 1 0 0 7XAU 3.0 10.1038/S41421-022-00405-2 2022-08-31
7XBW CX3C1 CX3CR1 Chemokine A (Rhodopsin) Human N/A 0 1 0 0 7XBW 2.8 10.1126/SCIADV.ABN8048 2022-07-13
7Y26 SSR2 SST2 Somatostatin A (Rhodopsin) Human N/A 0 1 0 0 7Y26 3.3 10.1038/S41589-022-01130-3 2022-10-19
6TPK OXYR OT Vasopressin and oxytocin A (Rhodopsin) Human N/A 0 3 0 0 6TPK 3.2 10.1126/SCIADV.ABB5419 2020-08-05
7E6T CASR CaS Calcium-sensing C (Glutamate) Human N/A 0 2 0 0 7E6T 3.0 10.7554/ELIFE.68578 2021-09-22
6K41 ADA2B α2B Adrenoceptors A (Rhodopsin) Human N/A 0 2 0 0 6K41 2.9 10.1038/S41589-020-0492-2 2020-04-15
8EFQ OPRM μ Opioid A (Rhodopsin) Human N/A 0 2 0 0 8EFQ 3.3 10.1016/J.CELL.2022.09.041 2022-11-09
7T90 ACM2 M2 Acetylcholine (muscarinic) A (Rhodopsin) Human N/A 2 2 0 0 7T90 3.3 2023-01-25
8HDO AA2BR A2B Adenosine A (Rhodopsin) Human N/A 0 0 0 0 8HDO 2.9 10.1038/S41421-022-00503-1 2023-01-18
8EFO OPRM μ Opioid A (Rhodopsin) Human N/A 0 2 0 0 8EFO 2.8 10.1016/J.CELL.2022.09.041 2022-11-09
7T8X ACM2 M2 Acetylcholine (muscarinic) A (Rhodopsin) Human N/A 2 2 0 0 7T8X 3.2 2023-01-25
7T96 ACM2 M2 Acetylcholine (muscarinic) A (Rhodopsin) Human N/A 2 2 0 0 7T96 3.2 2023-01-25
7YK6 RL3R2 RXFP4 Relaxin family peptide A (Rhodopsin) Human N/A 0 0 0 0 7YK6 3.0 10.1038/S41467-023-36182-Z 2023-03-01
7Y65 C5AR1 C5a1 Complement peptide A (Rhodopsin) Human N/A 0 1 0 0 7Y65 3.2 10.1038/S41422-023-00779-2 2023-03-01
6K42 ADA2B α2B Adrenoceptors A (Rhodopsin) Human N/A 0 2 0 0 6K42 4.1 2020-04-15
7F8Y CCKAR CCK1 Cholecystokinin A (Rhodopsin) Human N/A 0 3 0 0 7F8Y 2.5 10.1038/S41589-021-00866-8 2021-10-13
8E9X ACM4 M4 Acetylcholine (muscarinic) A (Rhodopsin) Human N/A 0 1 0 0 8E9X 2.7 10.1038/S41586-022-05489-0 2022-11-30
8TAO GRM5 mGlu5 Metabotropic glutamate C (Glutamate) Human N/A 0 2 0 0 8TAO 2.9 10.1101/2023.08.29.555158 2023-10-11
7YU6 LPAR1 LPA1 Lysophospholipid (LPA) A (Rhodopsin) Human N/A 0 1 0 0 7YU6 3.5 10.1038/S41467-022-33121-2 2022-10-05
7YU3 LPAR1 LPA1 Lysophospholipid (LPA) A (Rhodopsin) Human N/A 0 1 0 0 7YU3 3.4 10.1038/S41467-022-33121-2 2022-10-05
8HAF PTH1R PTH1 Parathyroid hormone B1 (Secretin) Human N/A 0 2 0 0 8HAF 3.3 10.1038/S41401-022-01032-Z 2022-12-21
8HAO PTH1R PTH1 Parathyroid hormone B1 (Secretin) Human N/A 0 2 0 0 8HAO 3.8 10.1038/S41401-022-01032-Z 2022-12-21
7Y89 GPR17 GPR17 A orphans A (Rhodopsin) Human N/A 0 2 0 0 7Y89 3.0 10.1002/MCO2.159 2022-10-12
7YU8 LPAR1 LPA1 Lysophospholipid (LPA) A (Rhodopsin) Human N/A 0 1 0 0 7YU8 4.5 10.1038/S41467-022-33121-2 2022-10-05
7Y67 C5AR1 C5a1 Complement peptide A (Rhodopsin) Human N/A 0 1 0 0 7Y67 2.8 10.1038/S41422-023-00779-2 2023-03-01
7T94 ACM2 M2 Acetylcholine (muscarinic) A (Rhodopsin) Human N/A 2 2 0 0 7T94 3.2 2023-01-25
8WVV LGR4 LGR4 A orphans A (Rhodopsin) Human N/A 0 2 0 0 8WVV 3.4 2024-10-30
8WM9 FZD4 FZD4 Frizzled F (Frizzled) Human N/A 0 0 0 0 8WM9 3.5 10.1038/S41467-024-52174-Z 2024-09-11
7XK2 HCAR2 HCA2 Hydroxycarboxylic acid A (Rhodopsin) Human N/A 0 1 0 0 7XK2 3.1 10.1038/S41467-023-37177-6 2023-02-22
8I2H FSHR FSH Glycoprotein hormone A (Rhodopsin) Human N/A 0 1 0 0 8I2H 6.0 10.1038/S41467-023-36170-3 2023-03-22
8E9Z ACM3 M3 Acetylcholine (muscarinic) A (Rhodopsin) Human N/A 0 2 0 0 8E9Z 2.7 10.1038/S41586-022-05489-0 2022-11-30
8GY7 ACTHR MC2 Melanocortin A (Rhodopsin) Human N/A 0 1 0 0 8GY7 3.3 10.1038/S41422-022-00751-6 2023-01-11
8F76 O51E2 OR51E2 Odorant family 51 O1 (fish-like odorant) Human N/A 0 1 0 0 8F76 3.1 10.1038/S41586-023-05798-Y 2023-03-22
6PS0 ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 1 2 0 2 6PS0 3.4 10.1107/S2052252519013137 2019-11-13
6TOD OX1R OX1 Orexin A (Rhodopsin) Human N/A 0 3 0 2 6TOD 2.1 10.1021/acs.jmedchem.9b01787 2020-01-01
8HCX EDNRB ETB Endothelin A (Rhodopsin) Human N/A 0 2 0 0 8HCX 3.5 2023-03-22
7CX3 PE2R2 EP2 Prostanoid A (Rhodopsin) Human N/A 0 0 0 0 7CX3 2.8 10.1126/SCIADV.ABF1268 2021-05-05
8HSC GPR20 GPR20 A orphans A (Rhodopsin) Human N/A 0 0 0 0 8HSC 3.2 10.1038/S41421-023-00520-8 2023-03-08
8XVJ EDNRA ETA Endothelin A (Rhodopsin) Human N/A 0 3 0 0 8XVJ 3.3 2024-08-28
6TQ6 OX1R OX1 Orexin A (Rhodopsin) Human N/A 0 2 0 2 6TQ6 2.6 10.1021/acs.jmedchem.9b01787 2020-01-01
8T8M GRM5 mGlu5 Metabotropic glutamate C (Glutamate) Human N/A 0 2 0 0 8T8M 3.0 10.1101/2023.08.29.555158 2023-10-11
7L0S NTR1 NTS1 Neurotensin A (Rhodopsin) Rat N/A 1 3 0 0 7L0S 4.5 10.1038/S41594-020-00554-6 2021-01-06
8EF5 OPRM μ Opioid A (Rhodopsin) Human N/A 0 2 0 0 8EF5 3.3 10.1016/J.CELL.2022.09.041 2022-11-09
8E3X PACR PAC1 VIP and PACAP B1 (Secretin) Human N/A 0 1 0 0 8E3X 2.3 10.1038/S41467-022-34629-3 2022-11-23
8WPG CASR CaS Calcium-sensing C (Glutamate) Human N/A 0 2 0 0 8WPG 2.7 10.1038/S41422-023-00892-2 2023-11-22
7VV6 MRGX2 MRGPRX2 A orphans A (Rhodopsin) Human N/A 0 0 0 0 7VV6 3.3 10.1038/S41586-021-04077-Y 2021-12-01
7LCK GLP1R GLP-1 Glucagon B1 (Secretin) Human N/A 0 1 0 0 7LCK 3.2 10.1016/J.STR.2021.04.008 2021-01-20
7CA3 GABR2 GABAB2 GABAB C (Glutamate) Human N/A 0 1 0 0 7CA3 4.5 10.1016/J.JMB.2020.09.023 2020-11-11
7YK7 RL3R2 RXFP4 Relaxin family peptide A (Rhodopsin) Human N/A 0 0 0 0 7YK7 2.8 10.1038/S41467-023-36182-Z 2023-03-01
8HBD EDNRB ETB Endothelin A (Rhodopsin) Human N/A 0 2 0 0 8HBD 3.0 2023-03-22
6WH4 5HT2A 5-HT2A 5-Hydroxytryptamine A (Rhodopsin) Human N/A 0 3 0 0 6WH4 3.4 10.1016/J.CELL.2020.08.024 2020-09-23
8F7X OPRX NOP Opioid A (Rhodopsin) Human N/A 0 1 0 0 8F7X 3.3 10.1016/J.CELL.2022.12.026 2022-12-14
6PS1 ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 1 2 0 2 6PS1 3.2 10.1107/S2052252519013137 2019-11-13
8ID4 FFAR4 FFA4 Free fatty acid A (Rhodopsin) Human N/A 0 0 0 0 8ID4 3.1 10.1126/SCIENCE.ADD6220 2023-03-15
8ID9 FFAR4 FFA4 Free fatty acid A (Rhodopsin) Human N/A 0 0 0 0 8ID9 3.0 10.1126/SCIENCE.ADD6220 2023-03-15
8F7S OPRD δ Opioid A (Rhodopsin) Human N/A 0 1 0 0 8F7S 3.0 10.1016/J.CELL.2022.12.026 2022-12-14
8HS3 GPR20 GPR20 A orphans A (Rhodopsin) Human N/A 0 0 0 0 8HS3 3.1 10.1038/S41421-023-00520-8 2023-03-08
8HIX GPR21 GPR21 A orphans A (Rhodopsin) Human N/A 0 1 0 0 8HIX 3.1 10.1038/S41467-023-35882-W 2023-03-15
7CA5 GABR2 GABAB2 GABAB C (Glutamate) Human N/A 0 1 0 0 7CA5 7.6 10.1016/J.JMB.2020.09.023 2020-11-11
8HDP AA2BR A2B Adenosine A (Rhodopsin) Human N/A 0 0 0 0 8HDP 3.2 10.1038/S41421-022-00503-1 2023-01-18
6D27 PD2R2 DP2 Prostanoid A (Rhodopsin) Human N/A 0 2 0 5 6D27 2.7 10.1016/J.MOLCEL.2018.08.009 2018-10-03
5YHL PE2R4 EP4 Prostanoid A (Rhodopsin) Human N/A 0 3 0 2 5YHL 4.2 10.1038/S41589-018-0131-3 2018-12-05
6ME2 MTR1A MT1 Melatonin A (Rhodopsin) Human N/A 0 3 0 2 6ME2 2.8 10.1038/S41586-019-1141-3 2019-04-24
8F7R OPRM μ Opioid A (Rhodopsin) Human N/A 0 2 0 0 8F7R 3.3 10.1016/J.CELL.2022.12.026 2022-12-14
8FN1 NTR1 NTS1 Neurotensin A (Rhodopsin) Rat N/A 0 1 0 0 8FN1 2.9 10.1021/ACS.BIOCHEM.3C00029 2023-03-29
5ZHP ACM3 M3 Acetylcholine (muscarinic) A (Rhodopsin) Rat N/A 0 3 0 4 5ZHP 3.1 10.1073/PNAS.1813988115 2018-11-28
8EFB OPRM μ Opioid A (Rhodopsin) Human N/A 0 2 0 0 8EFB 3.2 10.1016/J.CELL.2022.09.041 2022-11-09
8WG9 GRM4 mGlu4 Metabotropic glutamate C (Glutamate) Human N/A 0 1 0 0 8WG9 4.5 2024-11-27
8ID3 FFAR4 FFA4 Free fatty acid A (Rhodopsin) Human N/A 0 0 0 0 8ID3 3.1 10.1126/SCIENCE.ADD6220 2023-03-15
8X0E GRM5 mGlu5 Metabotropic glutamate C (Glutamate) Human N/A 2 2 0 0 8X0E 3.4 10.1038/S41467-024-55439-9 2024-11-06
7YU5 LPAR1 LPA1 Lysophospholipid (LPA) A (Rhodopsin) Human N/A 0 1 0 0 7YU5 3.3 10.1038/S41467-022-33121-2 2022-10-05
6TPJ OX2R OX2 Orexin A (Rhodopsin) Human N/A 0 2 0 3 6TPJ 2.7 10.1021/acs.jmedchem.9b01787 2020-01-01
8HJ0 GPR21 GPR21 A orphans A (Rhodopsin) Human N/A 0 1 0 0 8HJ0 3.1 10.1038/S41467-023-35882-W 2023-03-15
8I2G FSHR FSH Glycoprotein hormone A (Rhodopsin) Human N/A 0 1 0 0 8I2G 2.8 10.1038/S41467-023-36170-3 2023-03-29
8WCC TAAR1 TA1 Trace amine A (Rhodopsin) Mouse N/A 0 0 0 0 8WCC 3.0 10.1016/J.CELL.2023.10.014 2023-12-27
8ID6 FFAR4 FFA4 Free fatty acid A (Rhodopsin) Human N/A 0 0 0 0 8ID6 2.8 10.1126/SCIENCE.ADD6220 2023-03-15
8EF6 OPRM μ Opioid A (Rhodopsin) Human N/A 0 2 0 0 8EF6 3.2 10.1016/J.CELL.2022.09.041 2022-11-09
8X0D GRM5 mGlu5 Metabotropic glutamate C (Glutamate) Human N/A 2 2 0 0 8X0D 3.5 10.1038/S41467-024-55439-9 2024-11-06
8EFL OPRM μ Opioid A (Rhodopsin) Human N/A 0 2 0 0 8EFL 3.2 10.1016/J.CELL.2022.09.041 2022-11-09
8F7Q OPRM μ Opioid A (Rhodopsin) Human N/A 0 2 0 0 8F7Q 3.2 10.1016/J.CELL.2022.12.026 2022-12-14
8H8J GPR35 GPR35 A orphans A (Rhodopsin) Human N/A 0 1 0 0 8H8J 3.2 10.1038/S41421-022-00499-8 2023-02-08
8XFS LGR4 LGR4 A orphans A (Rhodopsin) Human N/A 0 2 0 0 8XFS 3.2 2024-12-04
7DGE GRM1 mGlu1 Metabotropic glutamate C (Glutamate) Human N/A 0 2 0 0 7DGE 3.7 10.1007/S13238-020-00808-5 2021-09-22
8DWG MRGX1 MRGPRX1 A orphans A (Rhodopsin) Human N/A 0 1 0 0 8DWG 2.7 10.1038/S41589-022-01173-6 2022-11-02
8DWC MRGX1 MRGPRX1 A orphans A (Rhodopsin) Human N/A 0 1 0 0 8DWC 2.9 10.1038/S41589-022-01173-6 2022-11-02
7KNU CALRL calcitonin-like Calcitonin B1 (Secretin) Human N/A 0 1 0 0 7KNU 3.5 10.1126/SCIENCE.ABF7258 2021-02-24
8G59 FFAR4 FFA4 Free fatty acid A (Rhodopsin) Human N/A 0 0 0 0 8G59 2.6 10.1126/SCIENCE.ADD6220 2023-03-08
7SUS APJ apelin Apelin A (Rhodopsin) Human N/A 0 3 0 0 7SUS 2.7 10.1038/S41594-022-00797-5 2022-07-27
5UIG AA2AR A2A Adenosine A (Rhodopsin) Human vapour diffusion 0 2 0 5 5UIG 3.5 10.1073/PNAS.1621423114 2017-02-08
7W40 GRPR BB2 Bombesin A (Rhodopsin) Human N/A 0 2 0 0 7W40 3.0 10.1073/PNAS.2216230120 2023-02-22
8E3Y VIPR1 VPAC1 VIP and PACAP B1 (Secretin) Human N/A 0 1 0 0 8E3Y 2.3 10.1038/S41467-022-34629-3 2022-11-23
8E3Z VIPR1 VPAC1 VIP and PACAP B1 (Secretin) Human N/A 0 1 0 0 8E3Z 2.7 10.1038/S41467-022-34629-3 2022-11-23
4Z35 LPAR1 LPA1 Lysophospholipid (LPA) A (Rhodopsin) Human in meso/LCP 0 3 0 5 4Z35 2.9 10.1016/J.CELL.2015.06.002 2015-06-03
8GHV CNR1 CB1 Cannabinoid A (Rhodopsin) Human N/A 0 0 0 0 8GHV 2.8 10.1038/S41467-023-37864-4 2023-05-24
8DZQ OPRK κ Opioid A (Rhodopsin) Human N/A 1 2 0 0 8DZQ 2.8 10.1038/S41586-023-06030-7 2023-05-03
8FLQ PTH1R PTH1 Parathyroid hormone B1 (Secretin) Human N/A 0 1 0 0 8FLQ 2.6 10.1016/J.STR.2023.04.002 2023-04-26
8XVK EDNRA ETA Endothelin A (Rhodopsin) Human N/A 0 3 0 0 8XVK 3.2 2024-08-28
8IY5 EDNRB ETB Endothelin A (Rhodopsin) Human N/A 0 1 0 0 8IY5 2.8 10.7554/ELIFE.85821 2023-08-16
7CUM GABR2 GABAB2 GABAB C (Glutamate) Human N/A 0 1 0 0 7CUM 3.5 10.1016/J.JMB.2020.09.023 2020-11-11
7YDH AGRE5 ADGRE5 ADGRE B2 (Adhesion) Human N/A 0 1 0 0 7YDH 3.1 10.1016/J.CHEMBIOL.2023.08.003 2023-07-12
8IBU MTLR motilin Motilin A (Rhodopsin) Human N/A 0 0 0 0 8IBU 3.5 10.1126/SCIADV.ADE9020 2023-04-12
8GEE ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8GEE 3.7 10.1038/S41586-024-07153-1 2024-03-06
5A8E ADRB1 β1 Adrenoceptors A (Rhodopsin) Wild turkey in meso/LCP 11 2 0 1 5A8E 2.4 10.1124/MOL.115.101030 2015-09-30
8CIC AA2AR A2A Adenosine A (Rhodopsin) Human N/A 0 3 0 0 8CIC 2.1 10.1038/S42004-023-00894-6 2023-05-31
7Y36 PTH1R PTH1 Parathyroid hormone B1 (Secretin) Human N/A 0 1 0 0 7Y36 2.8 2023-07-05
8GEH ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8GEH 4.0 10.1038/S41586-024-07153-1 2024-03-06
6TQ7 OX1R OX1 Orexin A (Rhodopsin) Human N/A 0 2 0 2 6TQ7 2.7 10.1021/acs.jmedchem.9b01787 2020-01-01
8GW8 PTH1R PTH1 Parathyroid hormone B1 (Secretin) Human N/A 0 2 0 0 8GW8 2.9 10.1038/S41586-023-06169-3 2023-06-14
8IUL PF2R FP Prostanoid A (Rhodopsin) Human N/A 0 0 0 0 8IUL 2.8 10.1038/S41467-023-38411-X 2023-07-12
8J1A GPR84 GPR84 A orphans A (Rhodopsin) Human N/A 0 0 0 0 8J1A 3.2 10.1038/S41467-023-38985-6 2023-06-21
8HMP GPR52 GPR52 A orphans A (Rhodopsin) Human N/A 0 1 0 0 8HMP 2.8 10.1002/MCO2.260 2023-06-21
7YM8 ADA1A α1A Adrenoceptors A (Rhodopsin) Human N/A 0 1 0 0 7YM8 2.9 10.1038/S41467-023-39310-X 2023-07-05
8JR9 PTH1R PTH1 Parathyroid hormone B1 (Secretin) Human N/A 0 2 0 0 8JR9 2.6 10.1038/S41586-023-06467-W 2023-08-02
8EIT FFAR1 FFA1 Free fatty acid A (Rhodopsin) Human N/A 0 1 0 0 8EIT 2.8 10.1073/PNAS.2219569120 2023-05-24
6PS2 ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 1 2 0 2 6PS2 2.4 10.1107/S2052252519013137 2019-11-13
8FLR PTH1R PTH1 Parathyroid hormone B1 (Secretin) Human N/A 0 1 0 0 8FLR 2.9 10.1016/J.STR.2023.04.002 2023-04-26
8IUK PF2R FP Prostanoid A (Rhodopsin) Human N/A 0 0 0 0 8IUK 2.7 10.1038/S41467-023-38411-X 2023-07-12
7ZL9 HCAR2 HCA2 Hydroxycarboxylic acid A (Rhodopsin) Human N/A 0 1 0 0 7ZL9 2.7 10.1038/S41467-023-37177-6 2023-04-12
5IU8 AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 9 3 0 4 5IU8 2.0 10.1021/acs.jmedchem.6b00653 2016-06-29
7Y64 C5AR1 C5a1 Complement peptide A (Rhodopsin) Human N/A 0 1 0 0 7Y64 2.9 10.1038/S41422-023-00779-2 2023-03-01
8F2B CALCR CT Calcitonin B1 (Secretin) Human N/A 0 1 0 0 8F2B 2.0 10.1038/S41589-023-01393-4 2023-08-02
7DDZ NPY2R Y2 Neuropeptide Y A (Rhodopsin) Human N/A 0 2 0 0 7DDZ 2.8 10.1038/S41467-021-21030-9 2021-01-27
7XV3 GP174 GPR174 A orphans A (Rhodopsin) Human N/A 0 0 0 0 7XV3 2.8 10.1038/S41467-023-36575-0 2023-02-15
8IW1 TAAR9 TAAR9 A orphans A (Rhodopsin) Mouse N/A 0 0 0 0 8IW1 3.4 10.1038/S41586-023-06106-4 2023-05-31
7YAC SSR2 SST2 Somatostatin A (Rhodopsin) Human N/A 0 2 0 0 7YAC 3.2 10.1038/S41467-023-36673-Z 2023-04-19
4DAJ ACM3 M3 Acetylcholine (muscarinic) A (Rhodopsin) Rat in meso/LCP 0 2 0 4 4DAJ 3.4 10.1038/NATURE10867 2012-02-22
8IBV MTLR motilin Motilin A (Rhodopsin) Human N/A 0 0 0 0 8IBV 3.2 10.1126/SCIADV.ADE9020 2023-04-12
7Y1F OPRK κ Opioid A (Rhodopsin) Human N/A 0 2 0 0 7Y1F 3.3 10.1093/PROCEL/PWAC033 2023-05-24
8H4I FFAR4 FFA4 Free fatty acid A (Rhodopsin) Human N/A 0 0 0 0 8H4I 3.1 10.1038/S41422-023-00835-X 2023-06-21
8UGW AA2AR A2A Adenosine A (Rhodopsin) Human N/A 0 2 0 0 8UGW 3.9 2024-12-18
8JD6 GRM4 mGlu4 Metabotropic glutamate C (Glutamate) Human N/A 0 1 0 0 8JD6 3.4 10.1038/S41422-023-00830-2 2023-06-21
6BD4 FZD4 FZD4 Frizzled F (Frizzled) Human N/A 0 3 0 2 6BD4 2.4 10.1038/S41586-018-0447-X 2018-08-22
7TRQ ACM4 M4 Acetylcholine (muscarinic) A (Rhodopsin) Human N/A 0 1 0 0 7TRQ 2.5 2023-05-17
4BUO NTR1 NTS1 Neurotensin A (Rhodopsin) Rat vapour diffusion 11 3 0 8 4BUO 2.8 10.1073/PNAS.1317903111 2014-01-29
6AK3 PE2R3 EP3 Prostanoid A (Rhodopsin) Human N/A 0 2 0 6 6AK3 2.9 10.1038/S41589-018-0171-8 2018-12-05
6PS3 ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 1 2 0 2 6PS3 2.5 10.1107/S2052252519013137 2019-11-13
7YMH ADA1A α1A Adrenoceptors A (Rhodopsin) Human N/A 0 1 0 0 7YMH 3.5 10.1038/S41467-023-39310-X 2023-07-05
7W41 GRPR BB2 Bombesin A (Rhodopsin) Human N/A 0 3 0 0 7W41 3.0 10.1073/PNAS.2216230120 2023-02-22
8JRV GLR glucagon Glucagon B1 (Secretin) Human N/A 0 2 0 0 8JRV 3.3 10.1038/S41586-023-06420-X 2023-08-16
7YDM AGRE5 ADGRE5 ADGRE B2 (Adhesion) Human N/A 0 1 0 0 7YDM 2.9 10.1016/J.CHEMBIOL.2023.08.003 2023-07-12
5VEW GLP1R GLP-1 Glucagon B1 (Secretin) Human in meso/LCP 10 4 0 5 5VEW 2.7 10.1038/NATURE22378 2017-05-24
8XVL EDNRA ETA Endothelin A (Rhodopsin) Human N/A 0 3 0 0 8XVL 3.2 2024-08-28
8FU6 GLR glucagon Glucagon B1 (Secretin) Human N/A 0 1 0 0 8FU6 2.9 10.1016/J.CELL.2023.02.028 2023-04-12
8IUM PF2R FP Prostanoid A (Rhodopsin) Human N/A 0 0 0 0 8IUM 3.1 10.1038/S41467-023-38411-X 2023-07-12
7Y3G GPR12 GPR12 A orphans A (Rhodopsin) Human N/A 0 0 0 0 7Y3G 2.8 10.1016/J.SCIB.2022.12.023 2023-06-07
8J19 GPR84 GPR84 A orphans A (Rhodopsin) Human N/A 0 0 0 0 8J19 3.2 10.1038/S41467-023-38985-6 2023-06-21
8IWM TAAR9 TAAR9 A orphans A (Rhodopsin) Mouse N/A 0 0 0 0 8IWM 3.2 10.1038/S41586-023-06106-4 2023-05-31
8JD3 GRM2 mGlu2 Metabotropic glutamate C (Glutamate) Human N/A 0 1 0 0 8JD3 3.3 10.1038/S41422-023-00830-2 2023-06-21
8HK5 C5AR1 C5a1 Complement peptide A (Rhodopsin) Human N/A 0 0 0 0 8HK5 3.0 10.1038/S41589-023-01339-W 2023-05-10
7VOD 5HT2A 5-HT2A 5-Hydroxytryptamine A (Rhodopsin) Human N/A 0 3 0 0 7VOD 3.3 10.1038/S41593-021-00971-W 2021-12-22
7XY6 AA2BR A2B Adenosine A (Rhodopsin) Human N/A 0 1 0 0 7XY6 3.0 10.1126/SCIADV.ADD3709 2023-05-03
6FK8 OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 2 0 0 0 6FK8 2.9 10.1073/PNAS.1718084115 2018-04-04
7YDJ AGRE5 ADGRE5 ADGRE B2 (Adhesion) Human N/A 0 1 0 0 7YDJ 3.0 2023-07-12
8J18 GPR84 GPR84 A orphans A (Rhodopsin) Human N/A 0 0 0 0 8J18 2.9 10.1038/S41467-023-38985-6 2023-06-21
3V2Y S1PR1 S1P1 Lysophospholipid (S1P) A (Rhodopsin) Human in meso/LCP 2 4 0 5 3V2Y 2.8 2012-02-15
7XXH P2RY1 P2Y1 P2Y A (Rhodopsin) Human N/A 0 1 0 0 7XXH 2.9 2023-06-07
8GUR CNR2 CB2 Cannabinoid A (Rhodopsin) Human N/A 0 0 0 0 8GUR 2.8 10.1038/S41467-023-37112-9 2023-05-10
8DZR OPRK κ Opioid A (Rhodopsin) Human N/A 1 2 0 0 8DZR 2.6 10.1038/S41586-023-06030-7 2023-05-03
7EPB GRM2 mGlu2 Metabotropic glutamate C (Glutamate) Human N/A 0 2 0 0 7EPB 3.1 10.1038/S41586-021-03641-W 2021-06-23
2YDV AA2AR A2A Adenosine A (Rhodopsin) Human vapour diffusion 5 1 0 2 2YDV 2.6 10.1038/NATURE10136 2011-05-18
6MH8 AA2AR A2A Adenosine A (Rhodopsin) Human N/A 0 3 0 4 6MH8 4.2 10.1107/S205225251900263X 2019-04-24
8IW4 TAAR9 TAAR9 A orphans A (Rhodopsin) Mouse N/A 0 0 0 0 8IW4 3.5 10.1038/S41586-023-06106-4 2023-05-31
8DZP OPRK κ Opioid A (Rhodopsin) Human N/A 1 2 0 0 8DZP 2.7 10.1038/S41586-023-06030-7 2023-05-03
8GUS CNR2 CB2 Cannabinoid A (Rhodopsin) Human N/A 0 0 0 0 8GUS 3.0 10.1038/S41467-023-37112-9 2023-05-10
8H0P NMBR BB1 Bombesin A (Rhodopsin) Human N/A 0 0 0 0 8H0P 3.2 10.1038/S41422-022-00743-6 2023-08-09
6WQA AA2AR A2A Adenosine A (Rhodopsin) Human N/A 0 3 0 0 6WQA 2.0 10.1107/S2052252520012701 2020-11-18
7TRK ACM4 M4 Acetylcholine (muscarinic) A (Rhodopsin) Human N/A 0 1 0 0 7TRK 2.8 2023-05-17
6W25 MC4R MC4 Melanocortin A (Rhodopsin) Human N/A 0 3 0 0 6W25 2.8 10.1126/SCIENCE.AAZ8995 2020-04-29
7XXI P2Y12 P2Y12 P2Y A (Rhodopsin) Human N/A 0 1 0 0 7XXI 3.0 2023-06-07
6NBF PTH1R PTH1 Parathyroid hormone B1 (Secretin) Human N/A 0 2 0 1 6NBF 3.0 10.1126/SCIENCE.AAV7942 2019-04-17
7ZLY HCAR2 HCA2 Hydroxycarboxylic acid A (Rhodopsin) Human N/A 0 1 0 0 7ZLY 2.7 10.1038/S41467-023-37177-6 2023-04-12
7YDP AGRE5 ADGRE5 ADGRE B2 (Adhesion) Human N/A 0 1 0 0 7YDP 3.1 10.1016/J.CHEMBIOL.2023.08.003 2023-07-12
7XKA ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 1 3 0 0 7XKA 3.1 2023-04-26
8HS2 GPR20 GPR20 A orphans A (Rhodopsin) Human N/A 0 1 0 0 8HS2 3.1 10.1038/S41421-023-00520-8 2023-03-08
8JLZ 5HT6R 5-HT6 5-Hydroxytryptamine A (Rhodopsin) Human N/A 0 0 0 0 8JLZ 3.1 10.1016/J.BBRC.2023.05.126 2023-06-28
8EJK FFAR1 FFA1 Free fatty acid A (Rhodopsin) Human N/A 0 1 0 0 8EJK 3.4 10.1073/PNAS.2219569120 2023-05-24
8HK3 C3AR C3a Complement peptide A (Rhodopsin) Human N/A 0 1 0 0 8HK3 3.2 10.1038/S41589-023-01339-W 2023-05-10
8JRU GLR glucagon Glucagon B1 (Secretin) Human N/A 0 2 0 0 8JRU 3.5 10.1038/S41586-023-06420-X 2023-08-16
7XWO NK2R NK2 Tachykinin A (Rhodopsin) Human N/A 0 1 0 0 7XWO 2.7 2023-05-31
2I37 OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 0 0 0 0 2I37 4.2 10.1073/PNAS.0608022103 2006-10-17
8H0Q GRPR BB2 Bombesin A (Rhodopsin) Human N/A 0 0 0 0 8H0Q 3.3 10.1038/S41422-022-00743-6 2023-08-09
8GUT CNR2 CB2 Cannabinoid A (Rhodopsin) Human N/A 0 1 0 0 8GUT 3.0 10.1038/S41467-023-37112-9 2023-05-10
4Z36 LPAR1 LPA1 Lysophospholipid (LPA) A (Rhodopsin) Human in meso/LCP 2 3 0 5 4Z36 2.9 10.1016/J.CELL.2015.06.002 2015-06-03
8ZMG 5HT2A 5-HT2A 5-Hydroxytryptamine A (Rhodopsin) Human N/A 0 3 0 0 8ZMG 3.4 2024-08-28
8GGN ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8GGN 3.3 10.1038/S41586-024-07153-1 2024-03-06
8IA2 C5AR1 C5a1 Complement peptide A (Rhodopsin) Human N/A 0 1 0 0 8IA2 3.2 10.1016/J.CELL.2023.09.020 2023-10-18
8IJA HCAR2 HCA2 Hydroxycarboxylic acid A (Rhodopsin) Human N/A 0 2 0 0 8IJA 2.7 10.1038/S41421-023-00610-7 2024-01-03
8W89 TAAR1 TA1 Trace amine A (Rhodopsin) Human N/A 0 0 0 0 8W89 3.0 10.1038/S41586-023-06775-1 2023-11-22
8I9S C3AR C3a Complement peptide A (Rhodopsin) Human N/A 0 1 0 0 8I9S 3.3 10.1016/J.CELL.2023.09.020 2023-10-18
8I9L C3AR C3a Complement peptide A (Rhodopsin) Human N/A 0 1 0 0 8I9L 3.2 10.1016/J.CELL.2023.09.020 2023-10-18
8I95 C3AR C3a Complement peptide A (Rhodopsin) Human N/A 0 1 0 0 8I95 2.9 10.1016/J.CELL.2023.09.020 2023-10-18
8HVI GP132 GPR132 A orphans A (Rhodopsin) Human N/A 0 0 0 0 8HVI 3.0 10.1038/S42255-023-00899-4 2023-10-11
8HQE GP132 GPR132 A orphans A (Rhodopsin) Human N/A 0 0 0 0 8HQE 3.0 10.1038/S42255-023-00899-4 2023-10-11
8HOC HRH4 H4 Histamine A (Rhodopsin) Human N/A 0 1 0 0 8HOC 3.0 2023-12-20
8HNK CXCR3 CXCR3 Chemokine A (Rhodopsin) Human N/A 0 1 0 0 8HNK 3.0 10.1038/S41594-023-01175-5 2023-11-29
8GDB PE2R4 EP4 Prostanoid A (Rhodopsin) Human N/A 0 0 0 0 8GDB 3.1 10.1073/PNAS.2216329120 2024-01-10
8GD9 PE2R4 EP4 Prostanoid A (Rhodopsin) Human N/A 0 0 0 0 8GD9 3.2 10.1073/PNAS.2216329120 2024-01-10
8GCM PE2R4 EP4 Prostanoid A (Rhodopsin) Human N/A 0 0 0 0 8GCM 3.5 10.1073/PNAS.2216329120 2024-01-03
8FX5 ACM4 M4 Acetylcholine (muscarinic) A (Rhodopsin) Human N/A 0 1 0 0 8FX5 2.5 10.1038/S41467-023-41199-5 2023-09-13
8JZ7 HCAR2 HCA2 Hydroxycarboxylic acid A (Rhodopsin) Human N/A 0 0 0 0 8JZ7 2.6 10.1038/S41392-023-01625-Y 2023-10-04
8IRJ GP179 GPR179 C Orphans C (Glutamate) Human N/A 0 1 0 0 8IRJ 3.5 2024-09-18
8WC4 TAAR1 TA1 Trace amine A (Rhodopsin) Mouse N/A 0 0 0 0 8WC4 3.1 10.1016/J.CELL.2023.10.014 2023-12-27
8ITM GIPR GIP Glucagon B1 (Secretin) Human N/A 0 2 0 0 8ITM 3.1 10.1073/PNAS.2306145120 2023-10-18
6TPG OX2R OX2 Orexin A (Rhodopsin) Human N/A 0 2 0 3 6TPG 2.7 10.1021/acs.jmedchem.9b01787 2020-01-01
8WC7 TAAR1 TA1 Trace amine A (Rhodopsin) Mouse N/A 0 0 0 0 8WC7 3.1 10.1016/J.CELL.2023.10.014 2023-12-27
6UO8 GABR2 GABAB2 GABAB C (Glutamate) Human N/A 0 2 0 0 6UO8 3.6 10.1038/S41586-020-2408-4 2020-06-10
8JLR TAAR1 TA1 Trace amine A (Rhodopsin) Human N/A 0 0 0 0 8JLR 3.0 10.1038/S41586-023-06804-Z 2023-11-15
8KGK GPR61 GPR61 A orphans A (Rhodopsin) Human N/A 0 1 0 0 8KGK 3.2 10.1038/S41467-023-41654-3 2023-10-11
8JLJ TAAR1 TA1 Trace amine A (Rhodopsin) Mouse N/A 0 0 0 0 8JLJ 3.1 10.1038/S41586-023-06804-Z 2023-11-15
8XBH GPR34 GPR34 A orphans A (Rhodopsin) Human N/A 0 1 0 0 8XBH 2.8 2023-12-27
8IKJ AGRE5 ADGRE5 ADGRE B2 (Adhesion) Human N/A 0 3 0 0 8IKJ 3.2 10.1016/J.MOLCEL.2023.12.020 2024-02-14
8HJ1 GPR21 GPR21 A orphans A (Rhodopsin) Human N/A 0 0 0 0 8HJ1 3.3 10.1038/S41467-023-35882-W 2023-12-27
8U1U CCR8 CCR8 Chemokine A (Rhodopsin) Human N/A 0 1 0 0 8U1U 3.1 2023-12-20
8FYX 5HT1A 5-HT1A 5-Hydroxytryptamine A (Rhodopsin) Human N/A 0 1 0 0 8FYX 2.6 10.1038/S41586-024-07403-2 2024-05-15
8WCA TAAR1 TA1 Trace amine A (Rhodopsin) Human N/A 0 0 0 0 8WCA 3.5 10.1016/J.CELL.2023.10.014 2023-12-27
8W88 TAAR1 TA1 Trace amine A (Rhodopsin) Human N/A 0 0 0 0 8W88 2.6 10.1038/S41586-023-06775-1 2023-11-22
8SG1 CML1 chemerin Chemerin receptor A (Rhodopsin) Human N/A 0 2 0 0 8SG1 2.9 10.1371/JOURNAL.PBIO.3002188 2023-11-01
8JLK TAAR1 TA1 Trace amine A (Rhodopsin) Mouse N/A 0 0 0 0 8JLK 3.2 10.1038/S41586-023-06804-Z 2023-11-15
8J6P HCAR2 HCA2 Hydroxycarboxylic acid A (Rhodopsin) Human N/A 0 2 0 0 8J6P 2.6 10.1038/S41467-023-43537-Z 2023-12-06
8GGV ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8GGV 3.5 10.1038/S41586-024-07153-1 2024-03-06
7SIL CASR CaS Calcium-sensing C (Glutamate) Human N/A 0 1 0 0 7SIL 2.7 10.1073/PNAS.2115849118 2022-01-19
8K2X CXCR3 CXCR3 Chemokine A (Rhodopsin) Human N/A 0 1 0 0 8K2X 3.2 10.1038/S41421-023-00617-0 2023-11-29
8IHH HCAR2 HCA2 Hydroxycarboxylic acid A (Rhodopsin) Human N/A 0 1 0 0 8IHH 3.1 10.1038/S41467-023-41650-7 2023-08-30
8KH4 GP161 GPR161 A orphans A (Rhodopsin) Human N/A 0 2 0 0 8KH4 3.1 10.1038/S41467-023-41654-3 2023-10-11
6TPN OX2R OX2 Orexin A (Rhodopsin) Human N/A 0 2 0 3 6TPN 2.6 10.1021/acs.jmedchem.9b01787 2020-01-01
8IHJ HCAR3 HCA3 Hydroxycarboxylic acid A (Rhodopsin) Human N/A 0 1 0 0 8IHJ 3.1 10.1038/S41467-023-41650-7 2023-08-30
8ITL GIPR GIP Glucagon B1 (Secretin) Human N/A 0 2 0 0 8ITL 3.2 10.1073/PNAS.2306145120 2023-10-18
8GG7 ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8GG7 3.3 10.1038/S41586-024-07153-1 2024-03-06
8HPT C5AR1 C5a1 Complement peptide A (Rhodopsin) Mouse N/A 0 1 0 0 8HPT 3.4 HTTPS://DOI.ORG/10.1016/J.CELL.2023.09.020 2023-10-18
8THK ADA1A α1A Adrenoceptors A (Rhodopsin) Human N/A 0 3 0 0 8THK 2.6 10.1038/S41467-023-40524-2 2023-08-16
3DQB OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 0 0 0 0 3DQB 3.2 10.1038/NATURE07330 2008-09-23
7V9L GHRHR GHRH Glucagon B1 (Secretin) Human N/A 0 1 0 0 7V9L 2.6 10.1073/PNAS.2106606118 2022-04-06
6KO5 GHSR ghrelin Ghrelin A (Rhodopsin) Human N/A 0 2 0 0 6KO5 3.3 10.1038/S41467-020-17554-1 2020-08-12
8JZZ C5AR1 C5a1 Complement peptide A (Rhodopsin) Human N/A 0 1 0 0 8JZZ 3.3 10.1016/J.CELL.2023.09.020 2023-10-18
8WC6 TAAR1 TA1 Trace amine A (Rhodopsin) Mouse N/A 0 0 0 0 8WC6 3.2 10.1016/J.CELL.2023.10.014 2023-12-27
4XEE NTR1 NTS1 Neurotensin A (Rhodopsin) Rat in meso/LCP 3 3 0 5 4XEE 2.9 10.1038/NCOMMS8895 2015-07-29
8IEI GP156 GPR156 C Orphans C (Glutamate) Human N/A 0 1 0 0 8IEI 2.6 2024-02-14
8FYL 5HT1A 5-HT1A 5-Hydroxytryptamine A (Rhodopsin) Human N/A 0 1 0 0 8FYL 2.9 10.1038/S41586-024-07403-2 2024-05-15
8JLP TAAR1 TA1 Trace amine A (Rhodopsin) Human N/A 0 0 0 0 8JLP 3.2 10.1038/S41586-023-06804-Z 2023-11-15
7EPC GRM7 mGlu7 Metabotropic glutamate C (Glutamate) Human N/A 0 1 0 0 7EPC 4.0 10.1038/S41586-021-03641-W 2021-06-23
8GGY ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8GGY 3.9 10.1038/S41586-024-07153-1 2024-03-06
8GGZ ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8GGZ 3.9 10.1038/S41586-024-07153-1 2024-03-06
8IOD MC5R MC5 Melanocortin A (Rhodopsin) Human N/A 0 1 0 0 8IOD 2.6 10.1107/S0907444909042073 2023-09-20
8YZK GPC5D GPRC5D C Orphans C (Glutamate) Human N/A 0 1 0 0 8YZK 3.4 10.1038/S41467-024-49625-Y 2024-07-03
8PM2 TAA7F TAAR7F A orphans A (Rhodopsin) Mouse N/A 0 0 0 0 8PM2 2.9 10.1101/2023.07.07.547762 2023-08-09
8JLQ TAAR1 TA1 Trace amine A (Rhodopsin) Human N/A 0 0 0 0 8JLQ 2.8 10.1038/S41586-023-06804-Z 2023-11-15
8ZMF 5HT2C 5-HT2C 5-Hydroxytryptamine A (Rhodopsin) Human N/A 0 3 0 0 8ZMF 3.6 2024-08-28
8WC3 TAAR1 TA1 Trace amine A (Rhodopsin) Mouse N/A 0 0 0 0 8WC3 3.0 10.1016/J.CELL.2023.10.014 2023-12-27
8GE1 ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8GE1 3.4 10.1038/S41586-024-07153-1 2024-03-06
8WC8 TAAR1 TA1 Trace amine A (Rhodopsin) Human N/A 0 0 0 0 8WC8 2.9 10.1016/J.CELL.2023.10.014 2023-12-27
8WPU CASR CaS Calcium-sensing C (Glutamate) Human N/A 0 2 0 0 8WPU 3.1 10.1038/S41422-023-00892-2 2023-11-22
8JIU GLR glucagon Glucagon B1 (Secretin) Human N/A 0 2 0 0 8JIU 2.8 10.1073/PNAS.2303696120 2023-09-13
8GGJ ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8GGJ 3.5 10.1038/S41586-024-07153-1 2024-03-06
8JSP 5HT1A 5-HT1A 5-Hydroxytryptamine A (Rhodopsin) Human N/A 0 2 0 0 8JSP 3.7 10.1038/S41586-023-06804-Z 2023-11-15
8W8Q GP101 GPR101 A orphans A (Rhodopsin) Human N/A 0 0 0 0 8W8Q 2.9 10.1038/S41589-023-01456-6 2024-01-03
8U26 NK1R NK1 Tachykinin A (Rhodopsin) Human N/A 0 0 0 0 8U26 2.5 10.1038/S41592-023-02082-9 2023-11-15
7YFD HRH4 H4 Histamine A (Rhodopsin) Human N/A 0 0 0 0 7YFD 3.1 10.1038/S41467-023-42260-Z 2023-10-25
8JIT GLR glucagon Glucagon B1 (Secretin) Human N/A 0 2 0 0 8JIT 2.9 10.1073/PNAS.2303696120 2023-09-06
8GGM ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8GGM 3.2 10.1038/S41586-024-07153-1 2024-03-06
8W8B 5HT1A 5-HT1A 5-Hydroxytryptamine A (Rhodopsin) Human N/A 0 1 0 0 8W8B 3.0 10.1038/S41586-023-06775-1 2023-11-22
8GGL ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8GGL 3.2 10.1038/S41586-024-07153-1 2024-03-06
6PS4 ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 1 2 0 2 6PS4 2.6 10.1107/S2052252519013137 2019-11-13
6ZDV AA2AR A2A Adenosine A (Rhodopsin) Human N/A 0 3 0 0 6ZDV 2.1 10.1002/ANIE.202003788 2020-09-16
5IUB AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 9 3 0 4 5IUB 2.1 10.1021/acs.jmedchem.6b00653 2016-06-29
8FYE 5HT1A 5-HT1A 5-Hydroxytryptamine A (Rhodopsin) Human N/A 0 1 0 0 8FYE 2.9 10.1038/S41586-024-07403-2 2024-05-15
8GGT ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8GGT 3.5 10.1038/S41586-024-07153-1 2024-03-06
7SIN CASR CaS Calcium-sensing C (Glutamate) Human N/A 0 1 0 0 7SIN 5.9 10.1073/PNAS.2115849118 2022-01-19
8SAI GPR34 GPR34 A orphans A (Rhodopsin) Human N/A 0 2 0 0 8SAI 3.3 10.1073/PNAS.2308435120 2023-10-04
8GCP PE2R4 EP4 Prostanoid A (Rhodopsin) Human N/A 0 0 0 0 8GCP 3.1 10.1073/PNAS.2216329120 2024-01-03
8GGK ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8GGK 3.3 10.1038/S41586-024-07153-1 2024-03-06
8JLO TAAR1 TA1 Trace amine A (Rhodopsin) Human N/A 0 0 0 0 8JLO 3.5 10.1038/S41586-023-06804-Z 2023-11-15
8TB0 GPR61 GPR61 A orphans A (Rhodopsin) Human N/A 0 1 0 0 8TB0 3.5 2023-10-04
8GFV ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8GFV 3.1 10.1038/S41586-024-07153-1 2024-03-06
8GE8 ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8GE8 3.4 10.1038/S41586-024-07153-1 2024-03-06
5JQH ADRB2 β2 Adrenoceptors A (Rhodopsin) Human in meso/LCP 4 3 0 4 5JQH 3.2 10.1038/NATURE18636 2016-07-13
8GGB ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8GGB 3.5 10.1038/S41586-024-07153-1 2024-03-06
7F8X CCKAR CCK1 Cholecystokinin A (Rhodopsin) Human N/A 0 3 0 0 7F8X 3.0 10.1038/S41589-021-00866-8 2021-12-29
8GE9 ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8GE9 3.5 10.1038/S41586-024-07153-1 2024-03-06
8GE6 ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8GE6 3.4 10.1038/S41586-024-07153-1 2024-03-06
8POK HRH2 H2 Histamine A (Rhodopsin) Human N/A 0 0 0 0 8POK 3.4 10.1038/S41467-024-46096-Z 2024-03-06
7TUY GP183 GPR183 A orphans A (Rhodopsin) Human N/A 0 1 0 0 7TUY 3.0 10.1016/J.STR.2022.04.006 2022-04-13
4BWB NTR1 NTS1 Neurotensin A (Rhodopsin) Rat vapour diffusion 26 3 0 8 4BWB 3.6 10.1073/PNAS.1317903111 2014-01-29
8IYH HCAR2 HCA2 Hydroxycarboxylic acid A (Rhodopsin) Human N/A 0 1 0 0 8IYH 3.3 10.1038/S41467-024-46239-2 2024-03-06
8X0H GRM5 mGlu5 Metabotropic glutamate C (Glutamate) Human N/A 2 2 0 0 8X0H 4.1 10.1038/S41467-024-55439-9 2024-11-06
5XEZ GLR glucagon Glucagon B1 (Secretin) Human in meso/LCP 0 3 0 5 5XEZ 3.0 10.1038/NATURE22363 2017-05-24
6UO9 GABR2 GABAB2 GABAB C (Glutamate) Human N/A 0 2 0 0 6UO9 4.8 10.1038/S41586-020-2408-4 2020-06-10
8GG8 ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8GG8 3.3 10.1038/S41586-024-07153-1 2024-03-06
8GE3 ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8GE3 3.3 10.1038/S41586-024-07153-1 2024-03-06
8IQ4 PF2R FP Prostanoid A (Rhodopsin) Human N/A 0 0 0 0 8IQ4 2.7 10.1038/S41467-023-43922-8 2024-01-31
7E6U CASR CaS Calcium-sensing C (Glutamate) Human N/A 0 2 0 0 7E6U 6.0 10.7554/ELIFE.68578 2021-09-22
8GEJ ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8GEJ 4.2 10.1038/S41586-024-07153-1 2024-03-06
8JER HCAR2 HCA2 Hydroxycarboxylic acid A (Rhodopsin) Human N/A 0 1 0 0 8JER 3.5 10.1038/S41467-024-46239-2 2024-03-06
8JXT HRH4 H4 Histamine A (Rhodopsin) Human N/A 0 0 0 0 8JXT 3.1 10.1038/S41467-024-46840-5 2024-03-20
8GE5 ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8GE5 3.2 10.1038/S41586-024-07153-1 2024-03-06
8JGG MRGX1 MRGPRX1 A orphans A (Rhodopsin) Human N/A 0 0 0 0 8JGG 3.0 10.1038/S41467-023-40705-Z 2024-01-10
8J9N FZD1 FZD1 Frizzled F (Frizzled) Human N/A 0 1 0 0 8J9N 3.5 10.1038/S41421-023-00627-Y 2024-01-17
8IU2 OPSR OPN1LW Opsins A (Rhodopsin) Human N/A 0 0 0 0 8IU2 3.4 2024-03-27
8X0F GRM5 mGlu5 Metabotropic glutamate C (Glutamate) Human N/A 2 2 0 0 8X0F 3.3 10.1038/S41467-024-55439-9 2024-11-06
8PKM 5HT1A 5-HT1A 5-Hydroxytryptamine A (Rhodopsin) Human N/A 0 0 0 0 8PKM 2.9 2024-05-29
8GG9 ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8GG9 3.4 10.1038/S41586-024-07153-1 2024-03-06
9D3G CCR6 CCR6 Chemokine A (Rhodopsin) Human N/A 0 0 0 0 9D3G 3.3 2024-09-11
8GGE ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8GGE 3.5 10.1038/S41586-024-07153-1 2024-03-06
7SIM CASR CaS Calcium-sensing C (Glutamate) Human N/A 0 1 0 0 7SIM 2.7 10.1073/PNAS.2115849118 2022-01-19
8GFW ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8GFW 3.0 10.1038/S41586-024-07153-1 2024-03-06
6M9T PE2R3 EP3 Prostanoid A (Rhodopsin) Human N/A 0 3 0 5 6M9T 2.5 10.1038/S41589-018-0160-Y 2018-12-05
8GG2 ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8GG2 3.0 10.1038/S41586-024-07153-1 2024-03-06
6E59 NK1R NK1 Tachykinin A (Rhodopsin) Human N/A 0 2 0 2 6E59 3.4 10.1073/PNAS.1812717115 2018-12-12
8GEA ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8GEA 3.5 10.1038/S41586-024-07153-1 2024-03-06
8JT6 5HT1A 5-HT1A 5-Hydroxytryptamine A (Rhodopsin) Human N/A 0 1 0 0 8JT6 3.0 10.1016/J.CELL.2024.02.034 2024-02-28
5JTB AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 0 3 0 4 5JTB 2.8 10.1126/SCIADV.1602952 2017-05-31
8KGG P2Y10 P2RY10 A orphans A (Rhodopsin) Human N/A 0 0 0 0 8KGG 3.1 10.1016/J.CHEMBIOL.2024.08.005 2024-07-31
7VV0 MRGX2 MRGPRX2 A orphans A (Rhodopsin) Human N/A 0 0 0 0 7VV0 3.5 10.1038/S41586-021-04077-Y 2021-12-01
8C9W AA2AR A2A Adenosine A (Rhodopsin) Human N/A 0 3 0 0 8C9W 2.1 10.1038/S42004-023-00894-6 2023-07-12
8GEB ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8GEB 3.6 10.1038/S41586-024-07153-1 2024-03-06
8GG3 ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8GG3 3.1 10.1038/S41586-024-07153-1 2024-03-06
8I7W HCAR2 HCA2 Hydroxycarboxylic acid A (Rhodopsin) Human N/A 0 0 0 0 8I7W 3.4 10.1038/S41467-023-42764-8 2024-02-07
8J6L HCAR2 HCA2 Hydroxycarboxylic acid A (Rhodopsin) Human N/A 0 1 0 0 8J6L 3.1 10.1016/J.CELREP.2023.113406 2024-04-03
8GGA ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8GGA 3.5 10.1038/S41586-024-07153-1 2024-03-06
8JXX HRH4 H4 Histamine A (Rhodopsin) Human N/A 0 0 0 0 8JXX 3.1 10.1038/S41467-024-46840-5 2024-03-20
8I7V HCAR2 HCA2 Hydroxycarboxylic acid A (Rhodopsin) Human N/A 0 0 0 0 8I7V 2.8 10.1038/S41467-023-42764-8 2024-02-07
7YMJ ADA1A α1A Adrenoceptors A (Rhodopsin) Human N/A 0 1 0 0 7YMJ 3.4 10.1038/S41467-023-39310-X 2023-07-05
8IZ4 GPR34 GPR34 A orphans A (Rhodopsin) Human N/A 0 1 0 0 8IZ4 2.9 2024-04-10
8JGF MRGX1 MRGPRX1 A orphans A (Rhodopsin) Human N/A 0 1 0 0 8JGF 2.7 10.1038/S41467-023-40705-Z 2024-01-10
8IYW HCAR2 HCA2 Hydroxycarboxylic acid A (Rhodopsin) Human N/A 0 1 0 0 8IYW 3.5 10.1038/S41467-024-46239-2 2024-03-06
6UOA GABR2 GABAB2 GABAB C (Glutamate) Human N/A 0 2 0 0 6UOA 6.3 10.1038/S41586-020-2408-4 2020-06-10
8JHI FZD3 FZD3 Frizzled F (Frizzled) Human N/A 0 1 0 0 8JHI 3.2 2024-01-17
8GG5 ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8GG5 3.2 10.1038/S41586-024-07153-1 2024-03-06
8X0C GRM5 mGlu5 Metabotropic glutamate C (Glutamate) Human N/A 2 2 0 0 8X0C 3.2 10.1038/S41467-024-55439-9 2024-11-06
8K9K OPRM μ Opioid A (Rhodopsin) Human N/A 0 2 0 0 8K9K 3.0 10.1038/S41467-024-47792-6 2024-05-29
8JPP SUCR1 succinate Succinate A (Rhodopsin) Human N/A 0 0 0 0 8JPP 3.2 10.1038/S41422-024-00968-7 2024-05-22
8KFZ CCR8 CCR8 Chemokine A (Rhodopsin) Human N/A 0 0 0 0 8KFZ 3.3 10.1126/SCIADV.ADJ7500 2024-02-07
8GGQ ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8GGQ 3.4 10.1038/S41586-024-07153-1 2024-03-06
6MEO CCR5 CCR5 Chemokine A (Rhodopsin) Human N/A 0 1 0 0 6MEO 3.9 10.1038/S41586-018-0804-9 2018-12-12
8J21 FFAR3 FFA3 Free fatty acid A (Rhodopsin) Human N/A 0 1 0 0 8J21 3.3 10.1038/S41422-023-00914-Z 2024-01-24
8J20 FFAR3 FFA3 Free fatty acid A (Rhodopsin) Human N/A 0 1 0 0 8J20 3.2 10.1038/S41422-023-00914-Z 2024-01-24
8GG0 ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8GG0 2.9 10.1038/S41586-024-07153-1 2024-03-06
8JBF NK3R NK3 Tachykinin A (Rhodopsin) Human N/A 0 1 0 0 8JBF 3.0 10.1038/S41421-023-00564-W 2024-02-28
8JXV HRH4 H4 Histamine A (Rhodopsin) Human N/A 0 0 0 0 8JXV 3.2 10.1038/S41467-024-46840-5 2024-03-20
7EPE GRM2 mGlu2 Metabotropic glutamate C (Glutamate) Human N/A 0 2 0 0 7EPE 2.5 10.1038/S41586-021-03641-W 2021-06-23
8GH1 ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8GH1 4.1 10.1038/S41586-024-07153-1 2024-03-06
8JBG NK3R NK3 Tachykinin A (Rhodopsin) Human N/A 0 0 0 0 8JBG 2.8 2024-02-07
8JCY GRM2 mGlu2 Metabotropic glutamate C (Glutamate) Human N/A 0 1 0 0 8JCY 2.9 10.1038/S41422-023-00830-2 2023-06-21
6PS5 ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 1 2 0 2 6PS5 2.9 10.1107/S2052252519013137 2019-11-13
8PJK 5HT1A 5-HT1A 5-Hydroxytryptamine A (Rhodopsin) Human N/A 0 0 0 0 8PJK 2.4 2024-05-29
8QJ2 MC4R MC4 Melanocortin A (Rhodopsin) Human N/A 0 0 0 0 8QJ2 3.4 2024-09-25
8GGP ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8GGP 3.2 10.1038/S41586-024-07153-1 2024-03-06
8IQ6 PF2R FP Prostanoid A (Rhodopsin) Human N/A 0 0 0 0 8IQ6 3.4 10.1038/S41467-023-43922-8 2024-01-31
8GGS ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8GGS 3.5 10.1038/S41586-024-07153-1 2024-03-06
8K9L OPRM μ Opioid A (Rhodopsin) Human N/A 0 2 0 0 8K9L 3.1 10.1038/S41467-024-47792-6 2024-05-29
8IED GP156 GPR156 C Orphans C (Glutamate) Human N/A 0 1 0 0 8IED 3.3 2024-02-14
8SMV GP161 GPR161 A orphans A (Rhodopsin) Human N/A 0 0 0 0 8SMV 2.7 10.1101/2023.05.23.540554 2024-02-21
8GE4 ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8GE4 3.3 10.1038/S41586-024-07153-1 2024-03-06
7LCJ GLP1R GLP-1 Glucagon B1 (Secretin) Human N/A 0 1 0 0 7LCJ 2.8 2021-01-20
4XES NTR1 NTS1 Neurotensin A (Rhodopsin) Rat in meso/LCP 4 3 0 5 4XES 2.6 10.1038/NCOMMS8895 2015-07-29
8GFY ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8GFY 3.0 10.1038/S41586-024-07153-1 2024-03-06
6DS0 5HT2B 5-HT2B 5-Hydroxytryptamine A (Rhodopsin) Human N/A 1 3 0 1 6DS0 3.2 10.1038/s41594-018-0116-7 2018-08-29
6JOD AGTR2 AT2 Angiotensin A (Rhodopsin) Human N/A 0 2 0 0 6JOD 3.2 10.1016/J.STR.2019.12.003 2020-01-15
8JHB FZD6 FZD6 Frizzled F (Frizzled) Human N/A 0 2 0 0 8JHB 3.3 10.1038/S41421-023-00627-Y 2024-01-17
8GEC ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8GEC 3.5 10.1038/S41586-024-07153-1 2024-03-06
8IEP GP156 GPR156 C Orphans C (Glutamate) Human N/A 0 1 0 0 8IEP 2.6 2024-02-14
6H7J ADRB1 β1 Adrenoceptors A (Rhodopsin) Wild turkey N/A 6 3 0 2 6H7J 2.8 10.1126/SCIENCE.AAU5595 2018-10-17
8IYX GPR34 GPR34 A orphans A (Rhodopsin) Human N/A 0 1 0 0 8IYX 3.3 10.1073/PNAS.2308435120 2024-03-20
8X16 AA3R A3 Adenosine A (Rhodopsin) Human N/A 0 0 0 0 8X16 3.3 10.1038/S41467-024-47207-6 2024-04-24
8UNQ ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8UNQ 3.3 10.1038/S41586-024-07153-1 2024-03-06
7EWP GP158 GPR158 C Orphans C (Glutamate) Human N/A 0 1 0 0 7EWP 4.3 10.1038/S41467-021-27147-1 2021-12-01
8U8F GPR3 GPR3 A orphans A (Rhodopsin) Human N/A 0 1 0 0 8U8F 3.5 10.1021/ACS.BIOCHEM.3C00647 2024-03-06
8XGR EDNRB ETB Endothelin A (Rhodopsin) Human N/A 0 1 0 0 8XGR 3.2 2024-04-03
7EWR GP158 GPR158 C Orphans C (Glutamate) Human N/A 0 1 0 0 7EWR 4.7 10.1038/S41467-021-27147-1 2021-12-01
8X8L SSR5 SST5 Somatostatin A (Rhodopsin) Human N/A 0 0 0 0 8X8L 2.7 2024-06-12
8UO4 ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8UO4 4.0 10.1038/S41586-024-07153-1 2024-03-06
8UWL 5HT2A 5-HT2A 5-Hydroxytryptamine A (Rhodopsin) Human N/A 0 2 0 0 8UWL 2.8 10.1126/SCIENCE.ADN6354 2024-05-29
8JPS ACKR1 ACKR1 Chemokine A (Rhodopsin) Human N/A 0 2 0 0 8JPS 3.7 10.1016/J.CELL.2024.07.005 2024-07-31
8XOG GPER1 GPER Estrogen (G protein-coupled) A (Rhodopsin) Human N/A 0 0 0 0 8XOG 2.9 10.1038/S41422-024-00963-Y 2024-04-10
8XIP SSR1 SST1 Somatostatin A (Rhodopsin) Human N/A 0 0 0 0 8XIP 3.3 2024-07-03
8JCZ GRM2 mGlu2 Metabotropic glutamate C (Glutamate) Human N/A 0 1 0 0 8JCZ 3.0 10.1038/S41422-023-00830-2 2023-06-21
8UH3 5HT1E 5-HT1E 5-Hydroxytryptamine A (Rhodopsin) Human N/A 0 0 0 0 8UH3 3.3 10.1126/SCIADV.ADK4855 2024-05-01
6MET CCR5 CCR5 Chemokine A (Rhodopsin) Human N/A 0 1 0 0 6MET 4.5 10.1038/S41586-018-0804-9 2018-12-12
3NY8 ADRB2 β2 Adrenoceptors A (Rhodopsin) Human in meso/LCP 4 2 0 3 3NY8 2.8 10.1021/JA105108Q 2010-08-11
8V6U 5HT2A 5-HT2A 5-Hydroxytryptamine A (Rhodopsin) Human N/A 0 2 0 0 8V6U 3.0 10.1126/SCIENCE.ADN6354 2024-05-29
6FKC OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 2 0 0 0 6FKC 2.5 10.1073/PNAS.1718084115 2018-04-04
8UNS ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8UNS 3.4 10.1038/S41586-024-07153-1 2024-03-06
8SZG CASR CaS Calcium-sensing C (Glutamate) Human N/A 0 2 0 0 8SZG 3.6 10.1038/S41586-024-07055-2 2024-02-07
6WW2 FZD5 FZD5 Frizzled F (Frizzled) Human N/A 0 3 0 0 6WW2 3.7 10.7554/ELIFE.58464 2020-08-19
8WP1 SUCR1 succinate Succinate A (Rhodopsin) Human N/A 0 2 0 0 8WP1 3.2 10.1016/J.CELREP.2024.114381 2024-09-11
8WOG SUCR1 succinate Succinate A (Rhodopsin) Human N/A 0 2 0 0 8WOG 3.0 10.1016/J.CELREP.2024.114381 2024-09-11
8XFP LGR4 LGR4 A orphans A (Rhodopsin) Human N/A 0 0 0 0 8XFP 3.2 2024-12-04
7M3F CASR CaS Calcium-sensing C (Glutamate) Human N/A 0 2 0 0 7M3F 2.8 10.1038/S41586-021-03691-0 2021-06-30
8T3V FFAR1 FFA1 Free fatty acid A (Rhodopsin) Human N/A 0 1 0 0 8T3V 3.4 10.1126/SCIADV.ADJ2384 2024-01-24
8X0G GRM5 mGlu5 Metabotropic glutamate C (Glutamate) Human N/A 2 2 0 0 8X0G 3.0 10.1038/S41467-024-55439-9 2024-11-06
8UGY 5HT1E 5-HT1E 5-Hydroxytryptamine A (Rhodopsin) Human N/A 0 2 0 0 8UGY 3.3 10.1126/SCIADV.ADK4855 2024-05-01
8WST MCHR2 MCH2 Melanin-concentrating hormone A (Rhodopsin) Human N/A 0 1 0 0 8WST 2.4 10.1038/S41421-024-00679-8 2024-06-19
8JCW GRM2 mGlu2 Metabotropic glutamate C (Glutamate) Human N/A 0 1 0 0 8JCW 3.0 10.1038/S41422-023-00830-2 2023-06-21
8WU1 CNR1 CB1 Cannabinoid A (Rhodopsin) Human N/A 0 1 0 0 8WU1 3.2 10.1016/J.CELL.2023.11.017 2024-03-20
6PS7 AA2AR A2A Adenosine A (Rhodopsin) Human N/A 0 3 0 3 6PS7 1.9 10.1107/S2052252519013137 2019-11-13
8X79 PI2R IP Prostanoid A (Rhodopsin) Human N/A 0 0 0 0 8X79 2.4 10.1126/SCIADV.ADK5184 2024-03-06
9BJK OPRM μ Opioid A (Rhodopsin) Mouse N/A 0 1 0 0 9BJK 3.3 2024-07-17
6LPL AA2AR A2A Adenosine A (Rhodopsin) Human N/A 0 3 0 0 6LPL 2.0 10.1038/S41598-020-76277-X 2020-11-25
8XOH GPER1 GPER Estrogen (G protein-coupled) A (Rhodopsin) Human N/A 0 0 0 0 8XOH 3.2 10.1038/S41422-024-00963-Y 2024-04-10
6H7L ADRB1 β1 Adrenoceptors A (Rhodopsin) Wild turkey N/A 6 3 0 2 6H7L 2.7 10.1126/SCIENCE.AAU5595 2018-10-17
6FKD OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 2 0 0 0 6FKD 2.5 10.1073/PNAS.1718084115 2018-04-04
6VJM GABR2 GABAB2 GABAB C (Glutamate) Human N/A 0 2 0 0 6VJM 4.0 10.1038/S41586-020-2408-4 2020-06-10
6GT3 AA2AR A2A Adenosine A (Rhodopsin) Human N/A 0 3 0 4 6GT3 2.0 2019-06-26
6PS8 MTR1A MT1 Melatonin A (Rhodopsin) Human N/A 0 3 0 2 6PS8 3.3 10.1107/S2052252519013137 2019-11-13
8XJL PF2R FP Prostanoid A (Rhodopsin) Human N/A 0 1 0 0 8XJL 2.8 10.1016/J.CELREP.2024.113893 2024-02-28
8XIQ SSR3 SST3 Somatostatin A (Rhodopsin) Human N/A 0 1 0 0 8XIQ 2.7 2024-07-03
6IIU TA2R TP Prostanoid A (Rhodopsin) Human N/A 0 3 0 4 6IIU 2.5 10.1038/S41589-018-0170-9 2018-12-19
8GGW ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8GGW 3.6 10.1038/S41586-024-07153-1 2024-03-06
8UO2 ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8UO2 3.6 10.1038/S41586-024-07153-1 2024-03-06
6Z10 SUCR1 succinate Succinate A (Rhodopsin) Rat N/A 0 1 0 0 6Z10 2.3 10.1021/acs.jmedchem.0c01020 2020-09-16
8UNT ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8UNT 3.4 10.1038/S41586-024-07153-1 2024-03-06
8JCU GRM2 mGlu2 Metabotropic glutamate C (Glutamate) Human N/A 0 1 0 0 8JCU 2.8 10.1038/S41422-023-00830-2 2023-06-21
8GH0 ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8GH0 4.0 10.1038/S41586-024-07153-1 2024-03-06
8UNV ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8UNV 3.3 10.1038/S41586-024-07153-1 2024-03-06
8UO0 ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8UO0 3.5 10.1038/S41586-024-07153-1 2024-03-06
8JCV GRM2 mGlu2 Metabotropic glutamate C (Glutamate) Human N/A 0 1 0 0 8JCV 3.4 10.1038/S41422-023-00830-2 2023-06-21
8XOR PAR1 PAR1 Proteinase-activated A (Rhodopsin) Human N/A 0 1 0 0 8XOR 3.0 2024-09-18
8T3O FFAR4 FFA4 Free fatty acid A (Rhodopsin) Human N/A 0 4 0 0 8T3O 3.1 10.1126/SCIADV.ADJ2384 2024-01-17
5CGC GRM5 mGlu5 Metabotropic glutamate C (Glutamate) Human in meso/LCP 6 2 0 3 5CGC 3.1 10.1021/acs.jmedchem.5b00892 2015-08-12
8WA3 GIPR GIP Glucagon B1 (Secretin) Human N/A 0 2 0 0 8WA3 2.9 10.1038/S41421-024-00649-0 2024-03-06
8XOI GPER1 GPER Estrogen (G protein-coupled) A (Rhodopsin) Human N/A 0 0 0 0 8XOI 3.2 10.1038/S41422-024-00963-Y 2024-04-10
8XOJ GPER1 GPER Estrogen (G protein-coupled) A (Rhodopsin) Human N/A 0 0 0 0 8XOJ 3.1 10.1038/S41422-024-00963-Y 2024-04-10
8X17 AA3R A3 Adenosine A (Rhodopsin) Human N/A 0 0 0 0 8X17 3.2 10.1038/S41467-024-47207-6 2024-04-24
8GGX ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8GGX 3.6 10.1038/S41586-024-07153-1 2024-03-06
8WG8 GLR glucagon Glucagon B1 (Secretin) Human N/A 0 2 0 0 8WG8 2.7 10.1038/S41421-024-00649-0 2024-03-06
6TOS OX1R OX1 Orexin A (Rhodopsin) Human N/A 0 3 0 2 6TOS 2.1 10.1021/acs.jmedchem.9b01787 2020-01-15
6Z4Q NTR1 NTS1 Neurotensin A (Rhodopsin) Rat N/A 1 1 0 0 6Z4Q 2.9 10.1126/sciadv.abe5504 2021-02-10
8IEB GP156 GPR156 C Orphans C (Glutamate) Human N/A 0 1 0 0 8IEB 3.0 2024-02-14
8UNU ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8UNU 3.5 10.1038/S41586-024-07153-1 2024-03-06
8X2K GPR3 GPR3 A orphans A (Rhodopsin) Human N/A 0 0 0 0 8X2K 3.0 10.1038/S41422-023-00919-8 2024-04-03
8UNY ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8UNY 3.6 10.1038/S41586-024-07153-1 2024-03-06
8XQP T2R14 TAS2R14 Taste 2 T2 (Taste 2) Human N/A 0 1 0 0 8XQP 3.3 10.1038/S41586-024-07569-9 2024-07-10
8U02 DRD2 D2 Dopamine A (Rhodopsin) Human N/A 0 0 0 0 8U02 3.3 10.1038/S41467-024-50964-Z 2024-08-21
8XIO SSR1 SST1 Somatostatin A (Rhodopsin) Human N/A 0 0 0 0 8XIO 2.7 2024-07-03
8UNR ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8UNR 3.4 10.1038/S41586-024-07153-1 2024-03-06
8J9O FZD1 FZD1 Frizzled F (Frizzled) Human N/A 0 3 0 0 8J9O 3.4 10.1038/S41421-023-00627-Y 2024-01-17
7M3E CASR CaS Calcium-sensing C (Glutamate) Human N/A 0 2 0 0 7M3E 3.2 10.1038/S41586-021-03691-0 2021-06-30
8UNZ ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8UNZ 3.8 10.1038/S41586-024-07153-1 2024-03-06
8UO3 ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8UO3 3.5 10.1038/S41586-024-07153-1 2024-03-06
7DTT CASR CaS Calcium-sensing C (Glutamate) Human N/A 0 1 0 0 7DTT 3.8 10.1038/S41422-021-00474-0 2021-03-10
4J4Q OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 0 0 0 0 4J4Q 2.7 10.1002/ANIE.201302374 2013-10-30
2PED OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 0 0 0 0 2PED 3.0 10.1529/BIOPHYSJ.107.108225 2007-10-30
8XJM PF2R FP Prostanoid A (Rhodopsin) Human N/A 0 1 0 0 8XJM 2.9 10.1016/J.CELREP.2024.113893 2024-02-28
8UNO ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8UNO 3.3 10.1038/S41586-024-07153-1 2024-03-06
8XQN T2R14 TAS2R14 Taste 2 T2 (Taste 2) Human N/A 0 1 0 0 8XQN 3.1 10.1038/S41586-024-07569-9 2024-07-10
8VY7 T2R14 TAS2R14 Taste 2 T2 (Taste 2) Human N/A 0 1 0 0 8VY7 2.7 2024-04-03
8XIR SSR3 SST3 Somatostatin A (Rhodopsin) Human N/A 0 0 0 0 8XIR 2.5 2024-07-03
6N48 ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 1 3 0 1 6N48 3.2 10.1126/SCIENCE.AAW8981 2019-06-26
8XJN TA2R TP Prostanoid A (Rhodopsin) Human N/A 0 1 0 0 8XJN 3.1 2024-02-28
8WG7 GLP1R GLP-1 Glucagon B1 (Secretin) Human N/A 0 1 0 0 8WG7 2.5 10.1038/S41421-024-00649-0 2024-03-06
8WW2 GPR3 GPR3 A orphans A (Rhodopsin) Human N/A 0 0 0 0 8WW2 2.8 10.1038/S41422-024-00932-5 2024-02-14
8XGM CML2 chemerin 2 Chemerin receptor A (Rhodopsin) Human N/A 0 2 0 0 8XGM 3.3 2024-08-21
9ASB CASR CaS Calcium-sensing C (Glutamate) Human N/A 0 1 0 0 9ASB 3.4 2024-04-17
9IIX T2R14 TAS2R14 Taste 2 T2 (Taste 2) Human N/A 0 0 0 0 9IIX 2.9 2024-07-24
8XQT T2R14 TAS2R14 Taste 2 T2 (Taste 2) Human N/A 0 1 0 0 8XQT 2.9 10.1038/S41586-024-07569-9 2024-07-10
8RQQ AA2AR A2A Adenosine A (Rhodopsin) Human N/A 0 3 0 0 8RQQ 2.4 2024-04-03
8XGS KISSR kisspeptin Kisspeptin A (Rhodopsin) Human N/A 0 0 0 0 8XGS 3.0 10.1126/SCIADV.ADN7771 2024-10-30
3NYA ADRB2 β2 Adrenoceptors A (Rhodopsin) Human in meso/LCP 4 2 0 3 3NYA 3.2 10.1021/JA105108Q 2010-08-11
9F34 DRD3 D3 Dopamine A (Rhodopsin) Human N/A 1 1 0 0 9F34 3.1 2024-09-18
9AVG CASR CaS Calcium-sensing C (Glutamate) Human N/A 0 1 0 0 9AVG 3.6 2024-04-17
8TH4 AGTR1 AT1 Angiotensin A (Rhodopsin) Human N/A 0 3 0 0 8TH4 3.3 10.1038/S41589-024-01620-6 2024-05-22
8YW4 GIPR GIP Glucagon B1 (Secretin) Human N/A 0 2 0 0 8YW4 3.3 10.1038/S41421-024-00700-0 2024-09-18
8YKX SUCR1 succinate Succinate A (Rhodopsin) Human N/A 0 0 0 0 8YKX 2.7 10.1038/S41422-024-00984-7 2024-05-29
8K6M NPY1R Y1 Neuropeptide Y A (Rhodopsin) Human N/A 0 1 0 0 8K6M 3.3 2024-07-31
7ARO AA2AR A2A Adenosine A (Rhodopsin) Human N/A 0 3 0 0 7ARO 3.1 10.1021/acs.jmedchem.0c01856 2021-04-07
8YUV HRH3 H3 Histamine A (Rhodopsin) Human N/A 0 0 0 0 8YUV 3.0 2024-06-05
8YUU HRH3 H3 Histamine A (Rhodopsin) Human N/A 0 0 0 0 8YUU 2.7 10.1002/ADVS.202310120 2024-06-05
8JWY AA2AR A2A Adenosine A (Rhodopsin) Human N/A 0 3 0 0 8JWY 2.3 2023-08-16
9IIW T2R14 TAS2R14 Taste 2 T2 (Taste 2) Human N/A 0 0 0 0 9IIW 3.2 2024-07-24
9BQJ OPRM μ Opioid A (Rhodopsin) Mouse N/A 0 2 0 0 9BQJ 3.3 2024-09-11
6OS1 AGTR1 AT1 Angiotensin A (Rhodopsin) Human N/A 0 2 0 2 6OS1 2.8 10.1126/SCIENCE.AAY9813 2020-02-19
7DTW CASR CaS Calcium-sensing C (Glutamate) Human N/A 0 1 0 0 7DTW 4.5 10.1038/S41422-021-00474-0 2021-03-10
6I9K B1B1U5 Rhodopsin Opsins A (Rhodopsin) Hasarius adansoni N/A 0 0 0 0 6I9K 2.2 10.1073/PNAS.1902192116 2019-07-03
6O3C SMO SMO Frizzled F (Frizzled) Mouse N/A 0 2 0 1 6O3C 2.8 10.1038/S41586-019-1355-4 2019-07-03
8UXV O51G2 OR51G2 Odorant family 51 O1 (fish-like odorant) Human N/A 0 1 0 0 8UXV 3.2 10.1038/S41586-024-08126-0 2024-10-30
9BKK CCKAR CCK1 Cholecystokinin A (Rhodopsin) Human N/A 0 1 0 0 9BKK 2.5 10.1371/JOURNAL.PBIO.3002673 2024-05-22
9CBM ADA2A α2A Adrenoceptors A (Rhodopsin) Human N/A 0 3 0 0 9CBM 3.2 10.1038/S12276-024-01296-X 2024-09-11
4AMJ ADRB1 β1 Adrenoceptors A (Rhodopsin) Wild turkey vapour diffusion 8 3 0 1 4AMJ 2.3 10.1016/J.STR.2012.03.014 2012-05-23
8XZH APJ apelin Apelin A (Rhodopsin) Human N/A 0 0 0 0 8XZH 2.6 10.1016/J.CELL.2024.02.004 2024-03-20
8ZSV TAAR1 TA1 Trace amine A (Rhodopsin) Mouse N/A 0 1 0 0 8ZSV 3.0 2024-07-24
8SZF CASR CaS Calcium-sensing C (Glutamate) Human N/A 0 2 0 0 8SZF 2.8 10.1038/S41586-024-07055-2 2024-02-07
8XWP EDNRB ETB Endothelin A (Rhodopsin) Human N/A 0 2 0 0 8XWP 3.2 10.1038/S42003-024-06905-Z 2024-10-02
7DTU CASR CaS Calcium-sensing C (Glutamate) Human N/A 0 1 0 0 7DTU 4.4 10.1038/S41422-021-00474-0 2021-03-10
6GPS CCR2 CCR2 Chemokine A (Rhodopsin) Human N/A 0 2 0 2 6GPS 3.3 10.1016/J.STR.2018.10.027 2019-01-02
9AUC CALCR CT Calcitonin B1 (Secretin) Human N/A 0 1 0 0 9AUC 2.4 10.1021/ACS.BIOCHEM.4C00114 2024-04-24
8ZJD KISSR kisspeptin Kisspeptin A (Rhodopsin) Human N/A 0 2 0 0 8ZJD 3.1 2024-07-03
8Y69 LGR4 LGR4 A orphans A (Rhodopsin) Human N/A 0 2 0 0 8Y69 3.4 2024-12-04
8TR2 GRM3 mGlu3 Metabotropic glutamate C (Glutamate) Human N/A 0 1 0 0 8TR2 3.5 10.1101/2023.08.13.552748 2024-07-31
6IQL DRD4 D4 Dopamine A (Rhodopsin) Mouse N/A 0 2 0 0 6IQL 3.5 10.7554/ELIFE.48822 2019-12-04
8YUT HRH2 H2 Histamine A (Rhodopsin) Human N/A 0 1 0 0 8YUT 2.7 2024-06-05
9IJE ADRB3 β3 Adrenoceptors A (Rhodopsin) Human N/A 0 2 0 0 9IJE 2.3 10.1002/CPLU.202400288 2024-08-21
9AXF CASR CaS Calcium-sensing C (Glutamate) Human N/A 0 1 0 0 9AXF 3.5 10.1038/S41586-024-07331-1 2024-04-17
6Z4V NTR1 NTS1 Neurotensin A (Rhodopsin) Rat N/A 1 1 0 0 6Z4V 2.6 10.1126/sciadv.abe5504 2021-02-10
9AVL CASR CaS Calcium-sensing C (Glutamate) Human N/A 0 1 0 0 9AVL 3.8 2024-04-17
8WGB GRM2 mGlu2 Metabotropic glutamate C (Glutamate) Human N/A 0 1 0 0 8WGB 3.7 10.1038/S41467-024-54744-7 2024-10-30
8JT8 5HT2A 5-HT2A 5-Hydroxytryptamine A (Rhodopsin) Human N/A 0 3 0 0 8JT8 2.7 10.1016/J.CELL.2024.02.034 2024-02-28
8ZPS PRLHR PrRP Prolactin-releasing peptide A (Rhodopsin) Human N/A 0 0 0 0 8ZPS 3.0 10.1038/S41421-024-00724-6 2024-09-25
8K6N NPY2R Y2 Neuropeptide Y A (Rhodopsin) Human N/A 0 1 0 0 8K6N 3.2 2024-07-31
7SHF GP158 GPR158 C Orphans C (Glutamate) Human N/A 0 1 0 0 7SHF 3.4 10.1126/SCIENCE.ABL4732 2021-12-01
9BKJ CCKAR CCK1 Cholecystokinin A (Rhodopsin) Human N/A 0 1 0 0 9BKJ 2.6 10.1371/JOURNAL.PBIO.3002673 2024-05-22
8K3Z CXCR4 CXCR4 Chemokine A (Rhodopsin) Human N/A 0 2 0 0 8K3Z 2.8 2024-07-17
8K6O NPY1R Y1 Neuropeptide Y A (Rhodopsin) Human N/A 0 1 0 0 8K6O 3.3 2024-07-31
8ZR5 GP119 GPR119 GPR18, GPR55 and GPR119 A (Rhodopsin) Human N/A 0 0 0 0 8ZR5 3.3 2024-06-19
7M3G CASR CaS Calcium-sensing C (Glutamate) Human N/A 0 2 0 0 7M3G 2.5 10.1038/S41586-021-03691-0 2021-06-30
5VRA AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 0 3 0 4 5VRA 2.4 10.1038/NPROT.2017.135 2017-12-13
8TR0 GRM3 mGlu3 Metabotropic glutamate C (Glutamate) Human N/A 0 1 0 0 8TR0 3.2 10.1101/2023.08.13.552748 2024-07-31
7PX4 AA2AR A2A Adenosine A (Rhodopsin) Human N/A 0 3 0 0 7PX4 2.3 10.1002/ANIE.202115545 2022-03-02
5ZBH NPY1R Y1 Neuropeptide Y A (Rhodopsin) Human N/A 1 3 0 3 5ZBH 3.0 10.1038/S41586-018-0046-X 2018-04-25
8WJX P2RY1 P2Y1 P2Y A (Rhodopsin) Human N/A 0 2 0 0 8WJX 3.2 2024-10-02
8YRG MRGX4 MRGPRX4 A orphans A (Rhodopsin) Human N/A 0 1 0 0 8YRG 3.1 2024-05-22
3EML AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 0 3 0 5 3EML 2.6 10.1126/SCIENCE.1164772 2008-10-14
8Y52 BRS3 BB3 Bombesin A (Rhodopsin) Human N/A 0 1 0 0 8Y52 2.9 10.1016/J.CELREP.2024.114511 2024-09-11
8JXS DRD1 D1 Dopamine A (Rhodopsin) Human N/A 0 2 0 0 8JXS 3.0 10.1016/J.NEURON.2024.07.003 2024-09-04
8XZI APJ apelin Apelin A (Rhodopsin) Human N/A 0 0 0 0 8XZI 2.7 2024-03-20
8ZH8 QRFPR QRFP Peptide P518 A (Rhodopsin) Human N/A 0 2 0 0 8ZH8 3.2 10.1038/S41467-024-49030-5 2024-07-03
6IIV TA2R TP Prostanoid A (Rhodopsin) Human N/A 0 3 0 4 6IIV 3.0 10.1038/S41589-018-0170-9 2018-12-19
8RLN AA2AR A2A Adenosine A (Rhodopsin) Human N/A 0 3 0 0 8RLN 2.4 2024-06-19
8TH3 AGTR1 AT1 Angiotensin A (Rhodopsin) Human N/A 0 3 0 0 8TH3 3.0 10.1038/S41589-024-01620-6 2024-05-22
8U4S CXCR4 CXCR4 Chemokine A (Rhodopsin) Human N/A 0 1 0 0 8U4S 3.4 10.1038/S41594-024-01397-1 2024-03-13
9AYF CASR CaS Calcium-sensing C (Glutamate) Human N/A 0 1 0 0 9AYF 3.6 10.1038/S41586-024-07331-1 2024-04-17
8XVE EDNRB ETB Endothelin A (Rhodopsin) Human N/A 0 2 0 0 8XVE 3.0 10.1038/S41421-024-00705-9 2024-08-28
7PYR AA2AR A2A Adenosine A (Rhodopsin) Human N/A 0 3 0 0 7PYR 2.6 10.1002/ANIE.202115545 2022-03-02
8ZRK GP119 GPR119 GPR18, GPR55 and GPR119 A (Rhodopsin) Human N/A 0 0 0 0 8ZRK 2.8 2024-06-19
6NI3 ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 2 0 3 6NI3 3.8 10.1038/S41594-019-0330-Y 2019-11-20
8VHF GP119 GPR119 GPR18, GPR55 and GPR119 A (Rhodopsin) Human N/A 0 0 0 0 8VHF 3.5 2024-10-30
8JJP CML2 chemerin 2 Chemerin receptor A (Rhodopsin) Human N/A 0 2 0 0 8JJP 2.9 2024-08-21
8IKG CNR1 CB1 Cannabinoid A (Rhodopsin) Human N/A 0 2 0 0 8IKG 3.4 10.1073/PNAS.2321532121 2024-06-05
7SHE GP158 GPR158 C Orphans C (Glutamate) Human N/A 0 1 0 0 7SHE 3.4 10.1126/SCIENCE.ABL4732 2021-12-01
8ZSP TAAR1 TA1 Trace amine A (Rhodopsin) Human N/A 0 1 0 0 8ZSP 3.1 10.1016/J.CELREP.2024.114505 2024-07-24
8XZF APJ apelin Apelin A (Rhodopsin) Human N/A 0 0 0 0 8XZF 3.0 10.1016/J.CELL.2024.02.004 2024-03-20
8ZCJ SSR5 SST5 Somatostatin A (Rhodopsin) Human N/A 0 0 0 0 8ZCJ 3.1 10.1038/S41401-024-01314-8 2024-07-10
8JCX GRM2 mGlu2 Metabotropic glutamate C (Glutamate) Human N/A 0 1 0 0 8JCX 3.0 10.1038/S41422-023-00830-2 2023-06-21
8XQR T2R14 TAS2R14 Taste 2 T2 (Taste 2) Human N/A 0 1 0 0 8XQR 3.2 10.1038/S41586-024-07569-9 2024-07-10
8QW4 FZD3 FZD3 Frizzled F (Frizzled) Human N/A 0 1 0 0 8QW4 2.9 10.1038/S41467-024-51451-1 2024-09-04
8ZBE SSR5 SST5 Somatostatin A (Rhodopsin) Human N/A 0 0 0 0 8ZBE 3.2 10.1038/S41401-024-01314-8 2024-07-10
9F33 DRD3 D3 Dopamine A (Rhodopsin) Human N/A 1 1 0 0 9F33 3.1 2024-09-18
8XVI EDNRA ETA Endothelin A (Rhodopsin) Human N/A 0 2 0 0 8XVI 3.3 10.1038/S41421-024-00705-9 2024-08-28
7M3J CASR CaS Calcium-sensing C (Glutamate) Human N/A 0 2 0 0 7M3J 4.1 10.1038/S41586-021-03691-0 2021-06-30
8YW5 GLR glucagon Glucagon B1 (Secretin) Human N/A 0 2 0 0 8YW5 2.8 10.1038/S41421-024-00700-0 2024-08-07
8K4O Q76SF8 ORF74 Unclassified A (Rhodopsin) HHV-8 N/A 0 2 0 0 8K4O 3.0 2024-07-24
2Y01 ADRB1 β1 Adrenoceptors A (Rhodopsin) Wild turkey vapour diffusion 8 3 0 1 2Y01 2.6 10.1038/NATURE09746 2011-03-30
8IKH CNR1 CB1 Cannabinoid A (Rhodopsin) Human N/A 0 2 0 0 8IKH 3.3 10.1073/PNAS.2321532121 2024-06-05
8IZB GP174 GPR174 A orphans A (Rhodopsin) Human N/A 0 1 0 0 8IZB 3.1 10.1371/JOURNAL.PBIO.3002387 2023-11-01
6OYA OPSD Rhodopsin Opsins A (Rhodopsin) Bovine N/A 0 0 0 0 6OYA 3.3 10.1016/J.MOLCEL.2019.06.007 2019-07-24
9JR3 PTH1R PTH1 Parathyroid hormone B1 (Secretin) Human N/A 0 1 0 0 9JR3 2.8 2024-10-16
6N4B CNR1 CB1 Cannabinoid A (Rhodopsin) Human N/A 0 0 0 3 6N4B 3.0 10.1016/J.CELL.2018.11.040 2019-01-30
8WWJ MCHR1 MCH1 Melanin-concentrating hormone A (Rhodopsin) Human N/A 0 1 0 0 8WWJ 3.0 2024-11-13
8HNM CXCR3 CXCR3 Chemokine A (Rhodopsin) Human N/A 0 1 0 0 8HNM 2.9 10.1038/S41594-023-01175-5 2023-11-29
8GTM CRFR1 CRF1 Corticotropin-releasing factor B1 (Secretin) Human N/A 2 2 0 0 8GTM 2.6 10.1038/S12276-023-01082-1 2023-09-13
8GTI CRFR1 CRF1 Corticotropin-releasing factor B1 (Secretin) Human N/A 2 2 0 0 8GTI 2.2 10.1038/S12276-023-01082-1 2023-09-13
8GTG CRFR1 CRF1 Corticotropin-releasing factor B1 (Secretin) Human N/A 2 2 0 0 8GTG 2.8 10.1038/S12276-023-01082-1 2023-09-13
8FCZ OPSD Rhodopsin Opsins A (Rhodopsin) Bovine N/A 0 0 0 0 8FCZ 3.7 10.1038/S41467-023-40911-9 2023-08-30
8A2P AA2AR A2A Adenosine A (Rhodopsin) Human N/A 0 3 0 0 8A2P 3.5 10.1107/S1600576723006428 2023-08-30
8E0G OPRM μ Opioid A (Rhodopsin) Mouse N/A 0 2 0 0 8E0G 2.1 10.1186/S12915-023-01689-W 2023-10-18
8WWI MCHR1 MCH1 Melanin-concentrating hormone A (Rhodopsin) Human N/A 0 1 0 0 8WWI 3.4 2024-11-13
8UY0 OR2T2 OR2T2 Odorant family 2 O2 (tetrapod specific odorant) Human N/A 0 1 0 0 8UY0 3.2 10.1038/S41586-024-08126-0 2024-10-30
8THL ADA1A α1A Adrenoceptors A (Rhodopsin) Human N/A 0 3 0 0 8THL 3.1 10.1038/S41467-023-40524-2 2023-08-16
8G94 S1PR1 S1P1 Lysophospholipid (S1P) A (Rhodopsin) Human N/A 0 1 0 0 8G94 3.2 10.7554/ELIFE.88204 2023-04-19
6GDG AA2AR A2A Adenosine A (Rhodopsin) Human Cryo-EM 1 2 0 5 6GDG 4.1 10.7554/ELIFE.35946 2018-05-16
1U19 OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 0 0 0 0 1U19 2.2 10.1016/J.JMB.2004.07.044 2004-10-12
8K4S MRGX4 MRGPRX4 A orphans A (Rhodopsin) Human N/A 0 0 0 0 8K4S 2.9 10.1016/J.CELL.2024.10.001 2024-11-06
6WZG SCTR secretin Glucagon B1 (Secretin) Human N/A 0 1 0 0 6WZG 2.3 10.1038/S41467-020-17791-4 2020-08-12
7TD2 LPAR1 LPA1 Lysophospholipid (LPA) A (Rhodopsin) Human N/A 0 2 0 0 7TD2 3.1 10.1038/S41467-022-28417-2 2022-02-09
8XML CCR8 CCR8 Chemokine A (Rhodopsin) Human N/A 0 0 0 0 8XML 2.6 2025-01-01
7WU3 AGRF1 ADGRF1 ADGRF B2 (Adhesion) Human N/A 0 2 0 0 7WU3 3.1 10.1038/S41586-022-04580-W 2022-04-27
5WKT OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 0 0 0 0 5WKT 3.2 10.1038/NPROT.2017.135 2017-12-13
7T2G OPRM μ Opioid A (Rhodopsin) Mouse N/A 0 1 0 0 7T2G 2.5 10.1038/S41589-022-01208-Y 2022-12-07
8JD0 GRM2 mGlu2 Metabotropic glutamate C (Glutamate) Human N/A 0 1 0 0 8JD0 3.3 10.1038/S41422-023-00830-2 2023-06-21
7WV9 CNR1 CB1 Cannabinoid A (Rhodopsin) Human N/A 0 0 0 0 7WV9 3.4 10.1038/S41589-022-01038-Y 2022-06-15
8P12 OPSD Rhodopsin Opsins A (Rhodopsin) Bovine N/A 0 0 0 0 8P12 3.2 2024-11-20
5DYS OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 3 0 0 0 5DYS 2.3 2016-08-10
9JR2 PTH1R PTH1 Parathyroid hormone B1 (Secretin) Human N/A 0 1 0 0 9JR2 2.8 2024-10-16
4ZUD AGTR1 AT1 Angiotensin A (Rhodopsin) Human in meso/LCP 0 3 0 5 4ZUD 2.8 10.1074/JBC.M115.689000 2015-10-07
7SR8 OX2R OX2 Orexin A (Rhodopsin) Human N/A 0 2 0 0 7SR8 3.3 10.1038/S41467-022-30601-3 2022-06-08
8JSO TAAR1 TA1 Trace amine A (Rhodopsin) Human N/A 0 0 0 0 8JSO 3.4 10.1038/S41586-023-06804-Z 2023-11-15
6OSA NTR1 NTS1 Neurotensin A (Rhodopsin) Human N/A 0 2 0 2 6OSA 3.0 10.1038/S41586-019-1337-6 2019-07-10
8XXU PD2R2 DP2 Prostanoid A (Rhodopsin) Human N/A 0 1 0 0 8XXU 2.5 2024-12-04
6TKO ADRB1 β1 Adrenoceptors A (Rhodopsin) Wild turkey N/A 4 2 0 0 6TKO 3.3 10.1038/S41586-020-2419-1 2020-06-17
8W87 TAAR1 TA1 Trace amine A (Rhodopsin) Human N/A 0 0 0 0 8W87 2.8 10.1038/S41586-023-06775-1 2023-11-22
6NBI PTH1R PTH1 Parathyroid hormone B1 (Secretin) Human N/A 0 2 0 1 6NBI 4.0 10.1126/SCIENCE.AAV7942 2019-04-17
7MBY CCKAR CCK1 Cholecystokinin A (Rhodopsin) Human N/A 0 1 0 0 7MBY 2.4 10.1371/JOURNAL.PBIO.3001295 2021-05-26
7JJO ADRB1 β1 Adrenoceptors A (Rhodopsin) Wild turkey N/A 0 3 0 0 7JJO 2.6 10.1016/J.MOLCEL.2020.08.001 2020-09-02
7XZ6 GP119 GPR119 GPR18, GPR55 and GPR119 A (Rhodopsin) Human N/A 0 0 0 0 7XZ6 2.8 10.1038/S41594-022-00816-5 2022-08-24
7VDM MRGX2 MRGPRX2 A orphans A (Rhodopsin) Human N/A 0 0 0 0 7VDM 3.0 10.1038/S41586-021-04077-Y 2021-12-01
9JKQ TAAR1 TA1 Trace amine A (Rhodopsin) Human N/A 0 0 0 0 9JKQ 2.7 10.1021/ACS.JMEDCHEM.4C01961 2024-10-16
8XYD PTAFR PAF Platelet-activating factor A (Rhodopsin) Human N/A 0 0 0 0 8XYD 2.9 10.1016/J.CELREP.2024.114422 2024-11-13
9GYO GPBAR GPBA Bile acid A (Rhodopsin) Human N/A 0 0 0 0 9GYO 2.5 2024-10-09
6OY9 OPSD Rhodopsin Opsins A (Rhodopsin) Bovine N/A 0 0 0 0 6OY9 3.9 10.1016/J.MOLCEL.2019.06.007 2019-07-24
8GUQ CNR2 CB2 Cannabinoid A (Rhodopsin) Human N/A 0 0 0 0 8GUQ 3.1 10.1038/S41467-023-37112-9 2023-05-10
7W0M APJ apelin Apelin A (Rhodopsin) Human N/A 0 2 0 0 7W0M 3.7 10.1038/S41594-022-00797-5 2022-07-27
7XW6 TSHR TSH Glycoprotein hormone A (Rhodopsin) Human N/A 0 2 0 0 7XW6 2.8 10.1038/S41586-022-05173-3 2022-08-17
4PXF OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 0 0 0 0 4PXF 2.8 10.1038/NCOMMS5801 2014-09-17
8TYW GPR6 GPR6 A orphans A (Rhodopsin) Human N/A 0 0 0 0 8TYW 3.4 10.1126/SCISIGNAL.ADO8741 2024-12-04
7CZ5 GHRHR GHRH Glucagon B1 (Secretin) Human N/A 0 2 0 0 7CZ5 2.6 10.1038/S41467-020-18945-0 2020-11-18
6OT0 SMO SMO Frizzled F (Frizzled) Human N/A 0 1 0 1 6OT0 3.9 10.1038/S41586-019-1286-0 2019-06-12
8JEI HCAR3 HCA3 Hydroxycarboxylic acid A (Rhodopsin) Human N/A 0 0 0 0 8JEI 2.7 10.1016/J.CELREP.2024.114895 2024-11-20
6P9X CRFR1 CRF1 Corticotropin-releasing factor B1 (Secretin) Human N/A 0 1 0 0 6P9X 2.9 10.1016/J.MOLCEL.2020.01.012 2020-02-05
6DDF OPRM μ Opioid A (Rhodopsin) Mouse Cryo-EM 0 2 0 4 6DDF 3.5 10.1038/S41586-018-0219-7 2018-06-13
8YN7 HRH3 H3 Histamine A (Rhodopsin) Human N/A 0 0 0 0 8YN7 2.8 2024-10-16
8YN4 HRH2 H2 Histamine A (Rhodopsin) Human N/A 0 1 0 0 8YN4 3.0 10.1038/S41467-024-52585-Y 2024-10-09
8JD4 GRM2 mGlu2 Metabotropic glutamate C (Glutamate) Human N/A 0 1 0 0 8JD4 2.9 10.1038/S41422-023-00830-2 2023-06-21
8WWM MCHR1 MCH1 Melanin-concentrating hormone A (Rhodopsin) Human N/A 0 1 0 0 8WWM 2.8 10.1038/S41421-024-00754-0 2024-11-13
8HCQ EDNRA ETA Endothelin A (Rhodopsin) Human N/A 0 2 0 0 8HCQ 3.0 2023-03-22
9IJ9 T2R14 TAS2R14 Taste 2 T2 (Taste 2) Human N/A 0 0 0 0 9IJ9 2.7 2024-07-24
6NWE OPSD Rhodopsin Opsins A (Rhodopsin) Bovine N/A 0 0 0 0 6NWE 2.7 2020-02-12
6QNO OPSD Rhodopsin Opsins A (Rhodopsin) Bovine N/A 0 0 0 0 6QNO 4.4 10.7554/ELIFE.46041 2019-07-10
7TYX CALCR CT Calcitonin B1 (Secretin) Human N/A 0 1 0 0 7TYX 2.6 10.1126/SCIENCE.ABM9609 2022-03-30
8DWH MRGX1 MRGPRX1 A orphans A (Rhodopsin) Human N/A 0 1 0 0 8DWH 3.3 10.1038/S41589-022-01173-6 2022-11-02
8G2Y AGRF1 ADGRF1 ADGRF B2 (Adhesion) Human N/A 0 1 0 0 8G2Y 3.4 10.1038/S41467-023-38083-7 2023-05-10
7F58 MC4R MC4 Melanocortin A (Rhodopsin) Human N/A 0 0 0 0 7F58 3.1 10.1038/S41422-021-00552-3 2021-11-03
6OIK ACM2 M2 Acetylcholine (muscarinic) A (Rhodopsin) Human N/A 3 2 0 2 6OIK 3.6 10.1126/SCIENCE.AAW5188 2019-05-08
5TZY FFAR1 FFA1 Free fatty acid A (Rhodopsin) Human in meso/LCP 3 1 0 6 5TZY 3.2 10.1038/NSMB.3417 2017-06-07
8XGO KISSR kisspeptin Kisspeptin A (Rhodopsin) Human N/A 0 0 0 0 8XGO 2.7 10.1126/SCIADV.ADN7771 2024-10-30
8YN5 HRH3 H3 Histamine A (Rhodopsin) Human N/A 0 0 0 0 8YN5 2.7 10.1038/S41467-024-52585-Y 2024-10-09
8YN9 HRH4 H4 Histamine A (Rhodopsin) Human N/A 0 1 0 0 8YN9 2.3 10.1038/S41467-024-52585-Y 2024-10-09
6PWC NTR1 NTS1 Neurotensin A (Rhodopsin) Human N/A 0 1 0 0 6PWC 4.9 10.1038/S41422-019-0256-2 2019-12-04
6B3J GLP1R GLP-1 Glucagon B1 (Secretin) Human Cryo-EM 0 1 0 5 6B3J 3.3 10.1038/NATURE25773 2018-02-21
7S1M GLP1R GLP-1 Glucagon B1 (Secretin) Human N/A 0 1 0 0 7S1M 2.4 10.1038/S41589-021-00945-W 2022-01-05
9EPR B1B1U5 Rhodopsin Opsins A (Rhodopsin) Hasarius adansoni N/A 0 0 0 0 9EPR 4.9 10.1038/S41467-024-53208-2 2024-10-30
8JPF NTR1 NTS1 Neurotensin A (Rhodopsin) Human N/A 0 0 0 0 8JPF 3.0 10.1038/S41586-023-06395-9 2023-08-09
8JD2 GRM2 mGlu2 Metabotropic glutamate C (Glutamate) Human N/A 0 1 0 0 8JD2 2.8 10.1038/S41422-023-00830-2 2023-06-21
9EW2 FZD7 FZD7 Frizzled F (Frizzled) Human N/A 0 1 0 0 9EW2 3.2 2024-10-02
6P9Y PACR PAC1 VIP and PACAP B1 (Secretin) Human N/A 0 1 0 2 6P9Y 3.0 10.1016/J.MOLCEL.2020.01.012 2020-02-05
8JEF HCAR3 HCA3 Hydroxycarboxylic acid A (Rhodopsin) Human N/A 0 0 0 0 8JEF 3.0 10.1016/J.CELREP.2024.114895 2024-12-18
8YN2 HRH1 H1 Histamine A (Rhodopsin) Human N/A 0 0 0 0 8YN2 2.7 10.1038/S41467-024-52585-Y 2024-10-09
6OS9 NTR1 NTS1 Neurotensin A (Rhodopsin) Human N/A 0 2 0 2 6OS9 3.0 10.1038/S41586-019-1337-6 2019-07-10
8YN8 HRH3 H3 Histamine A (Rhodopsin) Human N/A 0 0 0 0 8YN8 2.8 2024-10-16
5WS3 OX2R OX2 Orexin A (Rhodopsin) Human in meso/LCP 1 3 0 4 5WS3 2.3 10.1016/J.STR.2017.11.005 2017-12-13
8FD1 OPSD Rhodopsin Opsins A (Rhodopsin) Bovine N/A 0 0 0 0 8FD1 4.3 10.1038/S41467-023-40911-9 2023-08-30
8H4K FFAR4 FFA4 Free fatty acid A (Rhodopsin) Human N/A 0 0 0 0 8H4K 3.1 10.1038/S41422-023-00835-X 2023-06-21
7W57 NMUR2 NMU2 Neuromedin U A (Rhodopsin) Human N/A 0 1 0 0 7W57 3.2 10.1038/S41467-022-29683-W 2022-04-20
8GG4 ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8GG4 3.2 10.1038/S41586-024-07153-1 2024-03-06
8IEQ GP156 GPR156 C Orphans C (Glutamate) Human N/A 0 1 0 0 8IEQ 2.7 2024-02-14
8JHY HCAR2 HCA2 Hydroxycarboxylic acid A (Rhodopsin) Human N/A 0 0 0 0 8JHY 2.9 10.1016/J.MOLCEL.2023.07.030 2023-09-06
8K8J CNR1 CB1 Cannabinoid A (Rhodopsin) Human N/A 0 2 0 0 8K8J 2.9 10.1002/ADVS.202306311 2024-02-14
8IRV DRD5 D5 Dopamine A (Rhodopsin) Human N/A 0 0 0 0 8IRV 3.1 10.1038/S41422-023-00808-0 2023-06-07
4U15 ACM3 M3 Acetylcholine (muscarinic) A (Rhodopsin) Rat in meso/LCP 0 3 0 4 4U15 2.8 10.1016/J.STR.2014.08.022 2014-11-26
8HQN GP132 GPR132 A orphans A (Rhodopsin) Human N/A 0 0 0 0 8HQN 3.0 10.1038/S42255-023-00899-4 2023-10-11
8HN8 HRH4 H4 Histamine A (Rhodopsin) Human N/A 0 1 0 0 8HN8 3.0 2023-12-20
7YAE SSR2 SST2 Somatostatin A (Rhodopsin) Human N/A 0 0 0 0 7YAE 3.4 10.1038/S41467-023-36673-Z 2023-04-19
8FYN AA2AR A2A Adenosine A (Rhodopsin) Human N/A 0 3 0 0 8FYN 2.0 10.1038/S41467-023-36733-4 2023-03-08
8XFT LGR4 LGR4 A orphans A (Rhodopsin) Human N/A 0 0 0 0 8XFT 3.2 2024-12-04
8J6Q HCAR2 HCA2 Hydroxycarboxylic acid A (Rhodopsin) Human N/A 0 2 0 0 8J6Q 2.6 10.1038/S41467-023-43537-Z 2023-12-06
8H2G HCAR2 HCA2 Hydroxycarboxylic acid A (Rhodopsin) Human N/A 0 0 0 0 8H2G 3.0 2023-10-11
8J6I HCAR2 HCA2 Hydroxycarboxylic acid A (Rhodopsin) Human N/A 0 1 0 0 8J6I 2.9 2024-04-03
6WPW GLR glucagon Glucagon B1 (Secretin) Human N/A 0 1 0 0 6WPW 3.1 10.1126/SCIENCE.ABA3373 2020-08-12
4GBR ADRB2 β2 Adrenoceptors A (Rhodopsin) Human in meso/LCP 3 3 0 5 4GBR 4.0 10.1371/JOURNAL.PONE.0046039 2012-10-24
8Y53 BRS3 BB3 Bombesin A (Rhodopsin) Human N/A 0 1 0 0 8Y53 2.9 2024-09-11
7TRS ACM4 M4 Acetylcholine (muscarinic) A (Rhodopsin) Human N/A 0 1 0 0 7TRS 2.8 2023-05-17
8HA0 PTH1R PTH1 Parathyroid hormone B1 (Secretin) Human N/A 0 2 0 0 8HA0 2.6 10.1038/S41401-022-01032-Z 2022-12-21
7WC8 5HT2A 5-HT2A 5-Hydroxytryptamine A (Rhodopsin) Human N/A 0 3 0 0 7WC8 2.5 10.1126/SCIENCE.ABL8615 2022-01-26
8UNL ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8UNL 3.3 10.1038/S41586-024-07153-1 2024-03-06
8IJ3 HCAR2 HCA2 Hydroxycarboxylic acid A (Rhodopsin) Human N/A 0 2 0 0 8IJ3 3.3 10.1038/S41421-023-00610-7 2024-01-03
9IZF LPAR1 LPA1 Lysophospholipid (LPA) A (Rhodopsin) Human N/A 0 1 0 0 9IZF 3.1 2025-01-01
6PS6 ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 1 2 0 2 6PS6 2.7 10.1107/S2052252519013137 2019-11-13
5VBL APJ apelin Apelin A (Rhodopsin) Human in meso/LCP 5 3 0 5 5VBL 2.6 10.1016/J.STR.2017.04.008 2017-05-31
8SZH CASR CaS Calcium-sensing C (Glutamate) Human N/A 0 2 0 0 8SZH 3.1 10.1038/S41586-024-07055-2 2024-02-07
8JD1 GRM2 mGlu2 Metabotropic glutamate C (Glutamate) Human N/A 0 1 0 0 8JD1 3.7 10.1038/S41422-023-00830-2 2023-06-21
4EIY AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 0 3 0 4 4EIY 1.8 10.1126/SCIENCE.1219218 2012-07-25
7F0T DRD1 D1 Dopamine A (Rhodopsin) Human N/A 0 0 0 0 7F0T 3.1 10.1126/SCIADV.ABO4158 2022-06-15
8GE2 ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8GE2 3.3 10.1038/S41586-024-07153-1 2024-03-06
8WWL MCHR1 MCH1 Melanin-concentrating hormone A (Rhodopsin) Human N/A 0 1 0 0 8WWL 2.8 10.1038/S41421-024-00754-0 2024-11-13
8YW3 GLP1R GLP-1 Glucagon B1 (Secretin) Human N/A 0 1 0 0 8YW3 2.7 10.1038/S41421-024-00700-0 2024-09-18
4RWA OPRD δ Opioid A (Rhodopsin) Human in meso/LCP 0 2 0 5 4RWA 3.3 10.1038/NSMB.2965 2015-01-14
8IYS FFAR4 FFA4 Free fatty acid A (Rhodopsin) Human N/A 0 0 0 0 8IYS 3.0 10.1038/S41422-023-00835-X 2023-06-21
8IY6 EDNRB ETB Endothelin A (Rhodopsin) Human N/A 0 1 0 0 8IY6 3.1 10.7554/ELIFE.85821 2023-08-16
9IQT HCAR2 HCA2 Hydroxycarboxylic acid A (Rhodopsin) Human N/A 0 0 0 0 9IQT 2.9 10.1016/J.JMB.2024.168795 2024-10-02
8ZSS TAAR1 TA1 Trace amine A (Rhodopsin) Human N/A 0 1 0 0 8ZSS 3.1 2024-07-24
8HJ2 GPR21 GPR21 A orphans A (Rhodopsin) Human N/A 0 0 0 0 8HJ2 3.8 10.1038/S41467-023-35882-W 2023-03-15
7YKD CML1 chemerin Chemerin receptor A (Rhodopsin) Human N/A 0 0 0 0 7YKD 2.8 10.1073/PNAS.2214324120 2023-04-19
5KW2 FFAR1 FFA1 Free fatty acid A (Rhodopsin) Human in meso/LCP 4 1 0 6 5KW2 2.8 10.1038/S41467-017-01240-W 2018-05-02
7WXU AGRF1 ADGRF1 ADGRF B2 (Adhesion) Human N/A 0 0 0 0 7WXU 2.9 10.1038/S41467-022-33173-4 2022-09-28
8F0J CALCR CT Calcitonin B1 (Secretin) Human N/A 0 1 0 0 8F0J 2.0 10.1038/S41589-023-01393-4 2023-08-02
8F0K CALCR CT Calcitonin B1 (Secretin) Human N/A 0 1 0 0 8F0K 1.9 10.1038/S41589-023-01393-4 2023-08-02
7EJK ADA2A α2A Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 7EJK 3.4 10.1126/SCIADV.ABJ5347 2022-04-13
7DTV CASR CaS Calcium-sensing C (Glutamate) Human N/A 0 1 0 0 7DTV 3.5 10.1038/S41422-021-00474-0 2021-03-10
6ME7 MTR1B MT2 Melatonin A (Rhodopsin) Human N/A 0 3 0 3 6ME7 3.2 2019-04-24
8JGB MRGX1 MRGPRX1 A orphans A (Rhodopsin) Human N/A 0 1 0 0 8JGB 2.8 10.1038/S41467-023-40705-Z 2024-01-10
5GLH EDNRB ETB Endothelin A (Rhodopsin) Human in meso/LCP 0 3 0 7 5GLH 2.8 10.1038/nature19319 2016-09-07
8WZ2 QRFPR QRFP Peptide P518 A (Rhodopsin) Human N/A 0 0 0 0 8WZ2 2.7 10.1038/S41421-024-00670-3 2024-06-19
8JH7 FZD6 FZD6 Frizzled F (Frizzled) Human N/A 0 3 0 0 8JH7 3.2 10.1038/S41421-023-00627-Y 2024-01-17
8YKY T2R14 TAS2R14 Taste 2 T2 (Taste 2) Human N/A 0 1 0 0 8YKY 3.0 2024-07-10
8JPC NTR1 NTS1 Neurotensin A (Rhodopsin) Human N/A 0 0 0 0 8JPC 3.1 10.1038/S41586-023-06395-9 2023-08-09
8XOS PAR1 PAR1 Proteinase-activated A (Rhodopsin) Human N/A 0 1 0 0 8XOS 3.2 2024-09-18
7DB6 MTR1A MT1 Melatonin A (Rhodopsin) Human N/A 0 1 0 0 7DB6 3.3 10.1038/S41594-021-00634-1 2021-08-18
2Y04 ADRB1 β1 Adrenoceptors A (Rhodopsin) Wild turkey vapour diffusion 8 3 0 1 2Y04 3.1 10.1038/NATURE09746 2011-01-12
7F1Z DRD1 D1 Dopamine A (Rhodopsin) Human N/A 0 0 0 0 7F1Z 3.5 10.1126/SCIADV.ABO4158 2022-06-15
8UO1 ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8UO1 3.6 10.1038/S41586-024-07153-1 2024-03-06
7F8W GASR CCK2 Cholecystokinin A (Rhodopsin) Human N/A 0 2 0 0 7F8W 3.1 10.1038/S41589-021-00866-8 2021-10-13
8TRD GRM3 mGlu3 Metabotropic glutamate C (Glutamate) Human N/A 0 1 0 0 8TRD 3.4 10.1038/S41467-024-50548-X 2024-07-31
6WWZ CCR6 CCR6 Chemokine A (Rhodopsin) Human N/A 0 1 0 0 6WWZ 3.3 10.1038/S41467-020-16820-6 2020-06-24
8XZG APJ apelin Apelin A (Rhodopsin) Human N/A 0 0 0 0 8XZG 3.2 10.1016/J.CELL.2024.02.004 2024-03-27
4OO9 GRM5 mGlu5 Metabotropic glutamate C (Glutamate) Human in meso/LCP 6 3 0 3 4OO9 2.6 10.1038/NATURE13396 2014-07-02
7X8R GLP1R GLP-1 Glucagon B1 (Secretin) Human N/A 0 1 0 0 7X8R 2.6 10.1073/PNAS.2200155119 2022-06-29
7V3Z CNR1 CB1 Cannabinoid A (Rhodopsin) Human N/A 0 3 0 0 7V3Z 3.3 10.1021/JACS.1C06847 2021-11-24
8F2A CALCR CT Calcitonin B1 (Secretin) Human N/A 0 1 0 0 8F2A 2.2 10.1038/S41589-023-01393-4 2023-08-02
8U4T CXCR4 CXCR4 Chemokine A (Rhodopsin) Human N/A 0 1 0 0 8U4T 3.4 2024-03-13
8J6D C3AR C3a Complement peptide A (Rhodopsin) Human N/A 0 1 0 0 8J6D 3.1 10.1016/J.CELL.2023.09.020 2023-10-18
8GFZ ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8GFZ 3.0 10.1038/S41586-024-07153-1 2024-03-06
8XBE GPR34 GPR34 A orphans A (Rhodopsin) Human N/A 0 1 0 0 8XBE 3.4 10.1038/S41467-024-45046-Z 2024-05-15
6OS0 AGTR1 AT1 Angiotensin A (Rhodopsin) Human N/A 0 2 0 2 6OS0 2.9 10.1126/SCIENCE.AAY9813 2020-02-19
7F16 PTH2R PTH2 Parathyroid hormone B1 (Secretin) Human N/A 0 2 0 0 7F16 2.8 10.1073/PNAS.2101279118 2021-08-18
6WHA 5HT2A 5-HT2A 5-Hydroxytryptamine A (Rhodopsin) Human N/A 0 2 0 0 6WHA 3.4 10.1016/J.CELL.2020.08.024 2020-09-23
2YCY ADRB1 β1 Adrenoceptors A (Rhodopsin) Wild turkey vapour diffusion 8 4 0 1 2YCY 3.2 10.1073/PNAS.1100185108 2011-06-08
7VKT LT4R1 BLT1 Leukotriene A (Rhodopsin) Human N/A 0 0 0 0 7VKT 2.9 10.1038/S41467-022-28820-9 2022-03-09
8GEI ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8GEI 4.1 10.1038/S41586-024-07153-1 2024-03-06
8IJD HCAR2 HCA2 Hydroxycarboxylic acid A (Rhodopsin) Human N/A 0 2 0 0 8IJD 3.3 10.1038/S41421-023-00610-7 2024-01-03
8GDZ ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8GDZ 3.5 10.1038/S41586-024-07153-1 2024-03-06
9CHX ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 1 3 0 0 9CHX 3.5 10.1073/PNAS.2414544121 2024-11-13
8JBH NK3R NK3 Tachykinin A (Rhodopsin) Human N/A 0 0 0 0 8JBH 2.9 2024-02-07
5UEN AA1R A1 Adenosine A (Rhodopsin) Human in meso/LCP 1 3 0 8 5UEN 3.2 10.1016/j.cell.2017.01.042 2017-03-01
9EPP B1B1U5 Rhodopsin Opsins A (Rhodopsin) Hasarius adansoni N/A 0 2 0 0 9EPP 4.1 2024-10-23
8XZJ APJ apelin Apelin A (Rhodopsin) Human N/A 0 0 0 0 8XZJ 3.0 10.1016/J.CELL.2024.02.004 2024-03-20
8YNS MCHR1 MCH1 Melanin-concentrating hormone A (Rhodopsin) Human N/A 0 2 0 0 8YNS 3.3 2024-12-18
5D6L ADRB2 β2 Adrenoceptors A (Rhodopsin) Human in meso/LCP 3 2 0 2 5D6L 3.2 10.1038/NPROT.2017.057 2016-08-17
8HQM GP132 GPR132 A orphans A (Rhodopsin) Human N/A 0 0 0 0 8HQM 3.0 10.1038/S42255-023-00899-4 2023-10-11
8H4L FFAR4 FFA4 Free fatty acid A (Rhodopsin) Human N/A 0 0 0 0 8H4L 3.1 10.1038/S41422-023-00835-X 2023-06-21
7E2Y 5HT1A 5-HT1A 5-Hydroxytryptamine A (Rhodopsin) Human N/A 0 1 0 0 7E2Y 3.0 10.1038/S41586-021-03376-8 2021-04-14
8J6R HCAR2 HCA2 Hydroxycarboxylic acid A (Rhodopsin) Human N/A 0 2 0 0 8J6R 2.8 10.1038/S41467-023-43537-Z 2023-12-06
8WRB GPR34 GPR34 A orphans A (Rhodopsin) Human N/A 0 1 0 0 8WRB 2.9 10.1371/JOURNAL.PBIO.3002387 2023-11-08
6LRY EDNRB ETB Endothelin A (Rhodopsin) Human N/A 0 3 0 2 6LRY 3.0 10.1016/J.BBRC.2019.12.091 2020-02-12
8JII HCAR2 HCA2 Hydroxycarboxylic acid A (Rhodopsin) Human N/A 0 0 0 0 8JII 3.2 10.1016/J.MOLCEL.2023.07.030 2023-09-06
4X1H OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 0 0 0 0 4X1H 2.3 10.1016/J.STR.2015.09.015 2015-11-04
5IU4 AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 9 3 0 4 5IU4 1.7 10.1021/acs.jmedchem.6b00653 2016-06-29
8S4D APJ apelin Apelin A (Rhodopsin) Human N/A 0 3 0 0 8S4D 2.6 2024-12-04
5NM2 AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 9 3 0 4 5NM2 2.0 10.1038/S41467-017-00630-4 2017-09-27
2VT4 ADRB1 β1 Adrenoceptors A (Rhodopsin) Wild turkey vapour diffusion 8 4 0 1 2VT4 2.7 10.1038/NATURE07101 2008-06-24
5WF5 AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 1 3 0 4 5WF5 2.6 10.1016/J.STR.2017.12.013 2018-02-21
5TE5 OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 0 0 0 0 5TE5 4.0 10.1073/PNAS.1617446114 2017-03-15
3C9L OPSD Rhodopsin Opsins A (Rhodopsin) Bovine NA 0 0 0 0 3C9L 2.7 10.1107/S0907444908017162 2008-08-05
5N2S AA1R A1 Adenosine A (Rhodopsin) Human in meso/LCP 8 2 0 3 5N2S 3.3 10.1016/j.str.2017.06.012 2017-07-26
6OS2 AGTR1 AT1 Angiotensin A (Rhodopsin) Human N/A 0 2 0 2 6OS2 2.7 10.1126/SCIENCE.AAY9813 2020-02-19
5NX2 GLP1R GLP-1 Glucagon B1 (Secretin) Human vapour diffusion 12 2 0 5 5NX2 3.7 10.1038/NATURE22800 2017-06-14
5WIV DRD4 D4 Dopamine A (Rhodopsin) Human in meso/LCP 0 1 0 5 5WIV 2.1 10.1126/SCIENCE.AAN5468 2017-10-18
5X93 EDNRB ETB Endothelin A (Rhodopsin) Human in meso/LCP 8 3 0 7 5X93 2.2 10.1038/NSMB.3450 2017-08-16
5NDZ PAR2 PAR2 Proteinase-activated A (Rhodopsin) Human in meso/LCP 10 3 0 4 5NDZ 3.6 2017-05-03
5NDD PAR2 PAR2 Proteinase-activated A (Rhodopsin) Human in meso/LCP 10 3 0 4 5NDD 2.8 10.1038/NATURE22309 2017-05-03
3OE9 CXCR4 CXCR4 Chemokine A (Rhodopsin) Human in meso/LCP 2 3 0 6 3OE9 3.1 10.1126/SCIENCE.1194396 2010-10-27
6FFI GRM5 mGlu5 Metabotropic glutamate C (Glutamate) Human in meso/LCP 6 3 0 3 6FFI 2.2 2018-03-07
5IUA AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 9 3 0 4 5IUA 2.2 10.1021/acs.jmedchem.6b00653 2016-06-29
6KUW ADA2C α2C Adrenoceptors A (Rhodopsin) Human N/A 0 2 0 0 6KUW 2.8 2019-12-04
3AYN OPSD Rhodopsin Opsins A (Rhodopsin) Japanese flying squid vapour diffusion 0 0 0 0 3AYN 2.7 10.1016/J.JMB.2011.08.044 2011-08-17
4XNV P2RY1 P2Y1 P2Y A (Rhodopsin) Human in meso/LCP 1 2 0 6 4XNV 2.2 10.1038/NATURE14287 2015-04-01
8JIQ GLR glucagon Glucagon B1 (Secretin) Human N/A 0 2 0 0 8JIQ 3.4 2023-09-13
4ZJ8 OX1R OX1 Orexin A (Rhodopsin) Human in meso/LCP 1 2 0 4 4ZJ8 2.8 10.1038/NSMB.3183 2016-03-09
6FK6 OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 2 1 0 0 6FK6 2.4 10.1073/PNAS.1718084115 2018-04-04
5ZTY CNR2 CB2 Cannabinoid A (Rhodopsin) Human N/A 0 3 0 3 5ZTY 2.8 10.1016/J.CELL.2018.12.011 2019-01-30
7MT9 OPSD Rhodopsin Opsins A (Rhodopsin) Bovine N/A 0 0 0 0 7MT9 7.0 10.1038/S41586-021-03721-X 2021-07-07
5O9H C5AR1 C5a1 Complement peptide A (Rhodopsin) Human in meso/LCP 11 2 0 1 5O9H 2.7 10.1038/NATURE25025 2018-01-10
5IU7 AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 9 3 0 4 5IU7 1.9 10.1021/acs.jmedchem.6b00653 2016-06-29
4BV0 NTR1 NTS1 Neurotensin A (Rhodopsin) Rat vapour diffusion 29 3 0 8 4BV0 3.1 10.1073/PNAS.1317903111 2014-01-29
8JIM HCAR2 HCA2 Hydroxycarboxylic acid A (Rhodopsin) Human N/A 0 0 0 0 8JIM 3.0 10.1016/J.MOLCEL.2023.07.030 2023-09-06
6G79 5HT1B 5-HT1B 5-Hydroxytryptamine A (Rhodopsin) Human Cryo-EM 0 1 0 2 6G79 3.8 10.1038/S41586-018-0241-9 2018-06-20
6D35 Q98SW5 SMO Frizzled F (Frizzled) African clawed frog in meso/LCP 0 3 0 6 6D35 3.9 10.1016/J.CELL.2018.04.029 2018-05-23
5XRA CNR1 CB1 Cannabinoid A (Rhodopsin) Human in meso/LCP 4 3 0 5 5XRA 2.8 2017-07-12
6IBB SUCR1 succinate Succinate A (Rhodopsin) Rat N/A 0 1 0 2 6IBB 2.1 10.1038/S41586-019-1663-8 2019-08-14
8JIR GLP1R GLP-1 Glucagon B1 (Secretin) Human N/A 0 1 0 0 8JIR 2.6 10.1073/PNAS.2303696120 2023-09-06
6CMO OPSD Rhodopsin Opsins A (Rhodopsin) Human Cryo-EM 0 2 0 5 6CMO 4.5 10.1038/S41586-018-0215-Y 2018-06-20
5CGD GRM5 mGlu5 Metabotropic glutamate C (Glutamate) Human in meso/LCP 6 2 0 3 5CGD 2.6 10.1021/acs.jmedchem.5b00892 2015-08-12
5TUD 5HT2B 5-HT2B 5-Hydroxytryptamine A (Rhodopsin) Human in meso/LCP 1 3 0 5 5TUD 3.0 10.1073/PNAS.1700891114 2017-07-26
4BEY OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 3 0 0 0 4BEY 2.9 10.1038/EMBOR.2013.44 2013-05-08
5DSG ACM4 M4 Acetylcholine (muscarinic) A (Rhodopsin) Human in meso/LCP 0 3 0 3 5DSG 2.6 10.1038/NATURE17188 2016-03-16
4U14 ACM3 M3 Acetylcholine (muscarinic) A (Rhodopsin) Rat sponge mesophase 0 3 0 4 4U14 3.6 10.1016/J.STR.2014.08.022 2014-11-26
5EE7 GLR glucagon Glucagon B1 (Secretin) Human in meso/LCP 11 3 0 2 5EE7 2.5 10.1038/NATURE17414 2016-04-20
1L9H OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 0 0 0 0 1L9H 2.6 10.1073/PNAS.082666399 2002-05-15
5K2B AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 0 3 0 4 5K2B 2.5 10.1126/SCIADV.1600292 2016-09-21
4MBS CCR5 CCR5 Chemokine A (Rhodopsin) Human in meso/LCP 4 2 0 5 4MBS 2.7 10.1126/SCIENCE.1241475 2013-09-11
3AYM OPSD Rhodopsin Opsins A (Rhodopsin) Japanese flying squid vapour diffusion 0 0 0 0 3AYM 2.8 10.1016/J.JMB.2011.08.044 2011-08-17
5MZJ AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 9 3 0 4 5MZJ 2.0 10.1016/j.str.2017.06.012 2017-07-26
6Z66 NTR1 NTS1 Neurotensin A (Rhodopsin) Rat N/A 1 1 0 0 6Z66 3.2 10.1126/sciadv.abe5504 2021-02-10
5LWE CCR9 CCR9 Chemokine A (Rhodopsin) Human in meso/LCP 10 2 0 2 5LWE 2.8 10.1038/NATURE20606 2016-12-07
8WVW LGR4 LGR4 A orphans A (Rhodopsin) Human N/A 0 2 0 0 8WVW 3.5 2024-10-30
5UNH AGTR2 AT2 Angiotensin A (Rhodopsin) Human in meso/LCP 0 2 0 6 5UNH 2.9 10.1038/NATURE22035 2017-04-05
5VAI G1SGD4 GLP-1 Glucagon B1 (Secretin) Rabbit Cryo-EM 0 2 0 5 5VAI 4.1 10.1038/NATURE22394 2017-05-24
5DHG OPRX NOP Opioid A (Rhodopsin) Human in meso/LCP 0 2 0 5 5DHG 3.0 10.1016/J.STR.2015.07.024 2015-10-21
4DJH OPRK κ Opioid A (Rhodopsin) Human in meso/LCP 1 3 0 5 4DJH 2.9 10.1038/NATURE10939 2012-03-21
4UHR AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 5 1 0 2 4UHR 2.6 10.1124/mol.114.097360 2015-04-08
1HZX OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 0 0 0 0 1HZX 2.8 10.1021/BI0155091 2001-07-04
8JIP GLP1R GLP-1 Glucagon B1 (Secretin) Human N/A 0 1 0 0 8JIP 2.9 10.1073/PNAS.2303696120 2023-09-06
2I36 OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 0 0 0 0 2I36 4.1 2006-10-17
5OLG AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 9 3 0 4 5OLG 1.9 10.1038/S41598-017-18570-W 2018-01-17
5UNF AGTR2 AT2 Angiotensin A (Rhodopsin) Human in meso/LCP 0 2 0 6 5UNF 2.8 10.1038/NATURE22035 2017-04-05
5T1A CCR2 CCR2 Chemokine A (Rhodopsin) Human in meso/LCP 0 3 0 6 5T1A 2.8 10.1038/NATURE20605 2016-12-14
7WI6 GRM3 mGlu3 Metabotropic glutamate C (Glutamate) Human N/A 0 1 0 0 7WI6 3.7 10.1038/S41422-022-00623-Z 2022-03-16
6GPX CCR2 CCR2 Chemokine A (Rhodopsin) Human N/A 0 3 0 2 6GPX 2.7 10.1016/J.STR.2018.10.027 2019-01-02
3V2W S1PR1 S1P1 Lysophospholipid (S1P) A (Rhodopsin) Human in meso/LCP 2 4 0 5 3V2W 3.4 10.1126/SCIENCE.1215904 2012-02-15
8WGD GRM4 mGlu4 Metabotropic glutamate C (Glutamate) Human N/A 0 1 0 0 8WGD 4.5 2024-11-27
3CAP OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 0 0 0 0 3CAP 2.9 10.1038/NATURE07063 2008-06-24
6ZG4 ACM1 M1 Acetylcholine (muscarinic) A (Rhodopsin) Human N/A 0 3 0 0 6ZG4 2.3 2021-10-06
4RWS CXCR4 CXCR4 Chemokine A (Rhodopsin) Human in meso/LCP 3 3 0 5 4RWS 3.1 10.1126/SCIENCE.1261064 2015-02-11
4S0V OX2R OX2 Orexin A (Rhodopsin) Human in meso/LCP 1 3 0 4 4S0V 2.5 10.1038/NATURE14035 2015-01-14
8JIL HCAR2 HCA2 Hydroxycarboxylic acid A (Rhodopsin) Human N/A 0 0 0 0 8JIL 3.5 10.1016/J.MOLCEL.2023.07.030 2023-09-06
5T04 NTR1 NTS1 Neurotensin A (Rhodopsin) Rat in meso/LCP 4 3 0 5 5T04 3.3 10.1038/SREP38564 2016-12-21
4EA3 OPRX NOP Opioid A (Rhodopsin) Human in meso/LCP 0 2 0 5 4EA3 3.0 10.1038/NATURE11085 2012-04-25
5OM1 AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 9 3 0 3 5OM1 2.1 10.1038/S41598-017-18570-W 2018-01-17
7BTS ADRB1 β1 Adrenoceptors A (Rhodopsin) Human N/A 0 1 0 0 7BTS 3.1 10.1038/S41422-020-00424-2 2020-12-02
4DKL OPRM μ Opioid A (Rhodopsin) Mouse in meso/LCP 0 3 0 5 4DKL 2.8 10.1038/NATURE10954 2012-03-21
3ZEV NTR1 NTS1 Neurotensin A (Rhodopsin) Rat vapour diffusion 11 3 0 8 3ZEV 3.0 10.1073/PNAS.1317903111 2014-01-29
6H7O ADRB1 β1 Adrenoceptors A (Rhodopsin) Wild turkey N/A 6 3 0 2 6H7O 2.8 10.1126/SCIENCE.AAU5595 2018-10-17
8HNL CXCR3 CXCR3 Chemokine A (Rhodopsin) Human N/A 0 1 0 0 8HNL 3.0 10.1038/S41594-023-01175-5 2023-11-29
4QKX ADRB2 β2 Adrenoceptors A (Rhodopsin) Human in meso/LCP 5 3 0 5 4QKX 3.3 10.1073/PNAS.1410415111 2014-07-23
8IHK HCAR3 HCA3 Hydroxycarboxylic acid A (Rhodopsin) Human N/A 0 1 0 0 8IHK 3.2 10.1038/S41467-023-41650-7 2023-08-30
6HLO NK1R NK1 Tachykinin A (Rhodopsin) Human N/A 0 2 0 2 6HLO 2.4 10.1038/S41467-018-07939-8 2019-01-16
7BVQ ADRB1 β1 Adrenoceptors A (Rhodopsin) Human N/A 0 1 0 0 7BVQ 2.5 10.1038/S41422-020-00424-2 2020-12-02
9IYB PD2R2 DP2 Prostanoid A (Rhodopsin) Human N/A 0 0 0 0 9IYB 2.8 2024-12-04
4XT3 US28 US28 Unclassified A (Rhodopsin) strain AD169 in meso/LCP 0 2 0 1 4XT3 3.8 2015-03-04
7UL5 SSR2 SST2 Somatostatin A (Rhodopsin) Human N/A 0 1 0 0 7UL5 3.1 10.1038/S41594-022-00859-8 2022-06-29
8ZX5 GPR55 GPR55 GPR18, GPR55 and GPR119 A (Rhodopsin) Human N/A 0 0 0 0 8ZX5 3.0 2024-11-13
8YNT MCHR1 MCH1 Melanin-concentrating hormone A (Rhodopsin) Human N/A 0 2 0 0 8YNT 3.4 2024-12-18
6N51 GRM5 mGlu5 Metabotropic glutamate C (Glutamate) Human N/A 0 2 0 0 6N51 4.0 10.1038/S41586-019-0881-4 2019-01-23
7B6W ADA1B α1B Adrenoceptors A (Rhodopsin) Human N/A 0 1 0 0 7B6W 2.9 10.1038/s41467-021-27911-3 2022-01-12
8WVY LGR4 LGR4 A orphans A (Rhodopsin) Human N/A 0 2 0 0 8WVY 3.3 2024-10-30
3D4S ADRB2 β2 Adrenoceptors A (Rhodopsin) Human in meso/LCP 4 2 0 3 3D4S 2.8 10.1016/J.STR.2008.05.001 2008-06-17
6KUX ADA2A α2A Adrenoceptors A (Rhodopsin) Human N/A 0 2 0 0 6KUX 2.7 2019-12-04
9B9Z CNR1 CB1 Cannabinoid A (Rhodopsin) Human N/A 0 3 0 0 9B9Z 3.3 2024-11-20
5GLI EDNRB ETB Endothelin A (Rhodopsin) Human in meso/LCP 0 3 0 7 5GLI 2.5 10.1038/nature19319 2016-09-07
8WDT AA2AR A2A Adenosine A (Rhodopsin) Human N/A 0 2 0 0 8WDT 3.3 10.1016/J.BBRC.2023.149393 2024-01-17
6A94 5HT2A 5-HT2A 5-Hydroxytryptamine A (Rhodopsin) Human N/A 0 3 0 4 6A94 2.9 10.1038/S41594-018-0180-Z 2019-02-13
9K1C FFAR1 FFA1 Free fatty acid A (Rhodopsin) Human N/A 0 0 0 0 9K1C 3.2 10.1016/J.CELREP.2024.115024 2024-12-11
6AKX CCR5 CCR5 Chemokine A (Rhodopsin) Human N/A 4 3 0 3 6AKX 2.8 10.1021/acs.jmedchem.8b01077 2018-10-24
8YN3 HRH2 H2 Histamine A (Rhodopsin) Human N/A 0 1 0 0 8YN3 2.6 10.1038/S41467-024-52585-Y 2024-10-09
5ZKQ PTAFR PAF Platelet-activating factor A (Rhodopsin) Human N/A 5 3 0 3 5ZKQ 2.9 2018-06-20
6D9H AA1R A1 Adenosine A (Rhodopsin) Human Cryo-EM 0 1 0 6 6D9H 3.6 10.1038/S41586-018-0236-6 2018-06-20
9J5V LPAR1 LPA1 Lysophospholipid (LPA) A (Rhodopsin) Human N/A 0 1 0 0 9J5V 2.9 2024-11-27
2YDO AA2AR A2A Adenosine A (Rhodopsin) Human vapour diffusion 5 1 0 2 2YDO 3.0 2011-05-18
9DQJ MRGRD MRGPRD A orphans A (Rhodopsin) Human N/A 0 1 0 0 9DQJ 2.9 2024-12-11
9BA0 CNR1 CB1 Cannabinoid A (Rhodopsin) Human N/A 0 3 0 0 9BA0 3.1 2024-11-20
9CHU ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 1 3 0 0 9CHU 3.5 10.1073/PNAS.2414544121 2024-11-13
7WC4 5HT2A 5-HT2A 5-Hydroxytryptamine A (Rhodopsin) Human N/A 0 3 0 0 7WC4 3.2 10.1126/SCIENCE.ABL8615 2022-01-26
6D32 Q98SW5 SMO Frizzled F (Frizzled) African clawed frog in meso/LCP 0 3 0 6 6D32 3.8 10.1016/J.CELL.2018.04.029 2018-05-23
4PHU FFAR1 FFA1 Free fatty acid A (Rhodopsin) Human in meso/LCP 4 1 0 6 4PHU 2.3 10.1038/NATURE13494 2014-07-16
6ZDR AA2AR A2A Adenosine A (Rhodopsin) Human N/A 0 3 0 0 6ZDR 1.9 10.1002/ANIE.202003788 2020-09-16
6LI1 GPR52 GPR52 A orphans A (Rhodopsin) Human N/A 0 3 0 4 6LI1 2.9 10.1038/S41586-020-2019-0 2020-02-26
8Y45 OPRD δ Opioid A (Rhodopsin) Human N/A 0 2 0 0 8Y45 3.5 2024-11-27
4RWD OPRD δ Opioid A (Rhodopsin) Human in meso/LCP 0 2 0 5 4RWD 2.7 10.1038/NSMB.2965 2015-01-14
6PT0 CNR2 CB2 Cannabinoid A (Rhodopsin) Human N/A 0 0 0 1 6PT0 3.2 10.1016/J.CELL.2020.01.007 2020-02-12
7EZC AA2AR A2A Adenosine A (Rhodopsin) Human N/A 0 3 0 0 7EZC 3.8 10.1107/S2052252522001907 2022-04-13
6LML GLR glucagon Glucagon B1 (Secretin) Human N/A 0 2 0 1 6LML 3.9 10.1126/SCIENCE.AAZ5346 2020-04-01
9K1D FFAR2 FFA2 Free fatty acid A (Rhodopsin) Human N/A 0 0 0 0 9K1D 3.3 10.1016/J.CELREP.2024.115024 2024-12-11
6TOT OX1R OX1 Orexin A (Rhodopsin) Human N/A 0 3 0 2 6TOT 2.2 10.1021/acs.jmedchem.9b01787 2020-01-15
6PB1 CRFR2 CRF2 Corticotropin-releasing factor B1 (Secretin) Human N/A 0 2 0 0 6PB1 2.8 10.1016/J.MOLCEL.2020.01.013 2020-02-12
8TF5 GPR6 GPR6 A orphans A (Rhodopsin) Human N/A 0 2 0 0 8TF5 2.1 10.1126/SCISIGNAL.ADO8741 2024-12-04
3NY9 ADRB2 β2 Adrenoceptors A (Rhodopsin) Human in meso/LCP 4 2 0 3 3NY9 2.8 2010-08-11
8P15 OPSD Rhodopsin Opsins A (Rhodopsin) Bovine N/A 0 0 0 0 8P15 5.9 2024-11-20
6KPC CNR2 CB2 Cannabinoid A (Rhodopsin) Human N/A 0 3 0 3 6KPC 3.2 10.1016/J.CELL.2020.01.008 2020-02-12
2I35 OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 0 0 0 0 2I35 3.8 2006-10-17
8J46 O52E4 OR52E4 Odorant family 52 O1 (fish-like odorant) Human N/A 0 1 0 0 8J46 3.7 10.1038/S41467-023-43983-9 2023-12-20
3ZPQ ADRB1 β1 Adrenoceptors A (Rhodopsin) Wild turkey vapour diffusion 8 3 0 1 3ZPQ 2.8 10.1021/jm400140q 2013-04-03
9C1P CASR CaS Calcium-sensing C (Glutamate) Human N/A 0 2 0 0 9C1P 2.8 2024-10-02
5XR8 CNR1 CB1 Cannabinoid A (Rhodopsin) Human in meso/LCP 4 3 0 5 5XR8 3.0 10.1038/NATURE23272 2017-07-12
4QIM SMO SMO Frizzled F (Frizzled) Human in meso/LCP 0 3 0 5 4QIM 2.6 10.1038/NCOMMS5355 2014-07-23
7BU7 ADRB1 β1 Adrenoceptors A (Rhodopsin) Human N/A 0 1 0 0 7BU7 2.6 10.1038/S41422-020-00424-2 2020-12-02
6WIV GABR2 GABAB2 GABAB C (Glutamate) Human N/A 0 1 0 0 6WIV 3.3 10.1038/S41586-020-2452-0 2020-07-01
7MTQ GRM2 mGlu2 Metabotropic glutamate C (Glutamate) Human N/A 0 1 0 0 7MTQ 3.7 10.1038/S41586-021-03680-3 2021-07-07
8TLM CCR8 CCR8 Chemokine A (Rhodopsin) Human N/A 0 0 0 0 8TLM 2.9 10.1038/S41467-023-43601-8 2023-12-20
9AST XCR1 XCR1 Chemokine A (Rhodopsin) Human N/A 0 1 0 0 9AST 3.1 10.1073/PNAS.2405732121 2024-12-11
6KPF CNR2 CB2 Cannabinoid A (Rhodopsin) Human N/A 0 0 0 0 6KPF 2.9 2020-02-12
5YQZ GLR glucagon Glucagon B1 (Secretin) Human in meso/LCP 1 3 0 5 5YQZ 3.0 10.1038/NATURE25153 2018-01-17
9B9Y CNR1 CB1 Cannabinoid A (Rhodopsin) Human N/A 0 3 0 0 9B9Y 3.5 10.1038/S41467-024-54206-0 2024-11-20
6IBL ADRB1 β1 Adrenoceptors A (Rhodopsin) Wild turkey N/A 6 3 0 3 6IBL 2.7 10.1038/S41586-020-2419-1 2019-01-09
7WIH GRM3 mGlu3 Metabotropic glutamate C (Glutamate) Human N/A 0 1 0 0 7WIH 3.7 10.1038/S41422-022-00623-Z 2022-03-16
7BU6 ADRB1 β1 Adrenoceptors A (Rhodopsin) Human N/A 0 1 0 0 7BU6 2.7 10.1038/S41422-020-00424-2 2020-12-02
6KPG CNR1 CB1 Cannabinoid A (Rhodopsin) Human N/A 0 2 0 1 6KPG 3.0 2020-02-12
8ZRT EDNRB ETB Endothelin A (Rhodopsin) Human N/A 0 2 0 0 8ZRT 3.6 10.1038/S42003-024-06905-Z 2024-10-02
6AKY CCR5 CCR5 Chemokine A (Rhodopsin) Human N/A 4 3 0 3 6AKY 2.8 10.1021/acs.jmedchem.8b01077 2018-10-24
9EPQ B1B1U5 Rhodopsin Opsins A (Rhodopsin) Hasarius adansoni N/A 0 2 0 0 9EPQ 4.2 2024-10-23
9IMA GPC5D GPRC5D C Orphans C (Glutamate) Human N/A 0 1 0 0 9IMA 2.7 10.1016/J.JMB.2024.168748 2024-09-11
5OLV AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 9 3 0 3 5OLV 2.0 10.1038/S41598-017-18570-W 2018-01-17
6QZH CCR7 CCR7 Chemokine A (Rhodopsin) Human N/A 0 3 0 3 6QZH 2.1 10.1016/J.CELL.2019.07.028 2019-09-04
6K1Q EDNRB ETB Endothelin A (Rhodopsin) Human N/A 0 3 0 4 6K1Q 2.7 10.1038/S42003-019-0482-7 2019-07-17
8ZX4 GPR55 GPR55 GPR18, GPR55 and GPR119 A (Rhodopsin) Human N/A 0 1 0 0 8ZX4 2.9 2024-11-13
5OLH AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 9 3 0 3 5OLH 2.6 10.1038/S41598-017-18570-W 2018-01-17
6KUY ADA2A α2A Adrenoceptors A (Rhodopsin) Human N/A 0 2 0 0 6KUY 3.2 2019-12-04
8WWK MCHR1 MCH1 Melanin-concentrating hormone A (Rhodopsin) Human N/A 0 1 0 0 8WWK 2.6 10.1038/S41421-024-00754-0 2024-11-13
6OFJ OPSD Rhodopsin Opsins A (Rhodopsin) Bovine N/A 0 0 0 0 6OFJ 4.5 10.1074/JBC.RA119.010089 2019-08-21
6TQ9 OX1R OX1 Orexin A (Rhodopsin) Human N/A 0 3 0 2 6TQ9 2.7 10.1021/acs.jmedchem.9b01787 2020-01-01
6RNK SUCR1 succinate Succinate A (Rhodopsin) Rat N/A 0 1 0 2 6RNK 1.9 10.1038/S41586-019-1663-8 2019-08-14
4K5Y CRFR1 CRF1 Corticotropin-releasing factor B1 (Secretin) Human in meso/LCP 11 3 0 3 4K5Y 3.0 10.1038/NATURE12357 2013-07-17
8YIC S1PR1 S1P1 Lysophospholipid (S1P) A (Rhodopsin) Human N/A 0 1 0 0 8YIC 3.5 2024-12-11
6Z8N NTR1 NTS1 Neurotensin A (Rhodopsin) Rat N/A 1 1 0 0 6Z8N 2.8 10.1126/sciadv.abe5504 2021-02-10
6W2Y GABR1 GABAB1 GABAB C (Glutamate) Human N/A 0 2 0 0 6W2Y 3.2 10.1038/S41586-020-2469-4 2020-07-01
2HPY OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 0 0 0 0 2HPY 2.8 10.1073/PNAS.0601765103 2006-08-22
8XGU KISSR kisspeptin Kisspeptin A (Rhodopsin) Human N/A 0 0 0 0 8XGU 3.0 10.1126/SCIADV.ADN7771 2024-10-30
8WVU LGR4 LGR4 A orphans A (Rhodopsin) Human N/A 0 2 0 0 8WVU 3.6 2024-10-30
5OM4 AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 9 3 0 3 5OM4 2.0 10.1038/S41598-017-18570-W 2018-01-17
6ZA8 NTR1 NTS1 Neurotensin A (Rhodopsin) Rat N/A 1 1 0 0 6ZA8 2.7 10.1126/sciadv.abe5504 2021-02-10
6VN7 VIPR1 VPAC1 VIP and PACAP B1 (Secretin) Human N/A 0 1 0 0 6VN7 3.2 10.1038/S41467-020-17933-8 2020-09-02
6OMM FPR2 FPR2/ALX Formylpeptide A (Rhodopsin) Human N/A 0 1 0 1 6OMM 3.2 10.1038/S41467-020-14728-9 2020-02-26
6XBK SMO SMO Frizzled F (Frizzled) Human N/A 0 1 0 0 6XBK 3.2 10.1038/S41589-020-0646-2 2020-09-30
6M1H PACR PAC1 VIP and PACAP B1 (Secretin) Human N/A 0 2 0 0 6M1H 3.6 10.1038/S41422-020-0280-2 2020-03-11
8IHF HCAR2 HCA2 Hydroxycarboxylic acid A (Rhodopsin) Human N/A 0 1 0 0 8IHF 3.0 10.1038/S41467-023-41650-7 2023-08-30
8IHB HCAR2 HCA2 Hydroxycarboxylic acid A (Rhodopsin) Human N/A 0 1 0 0 8IHB 2.9 10.1038/S41467-023-41650-7 2023-09-13
7MTA OPSD Rhodopsin Opsins A (Rhodopsin) Bovine N/A 0 0 0 0 7MTA 4.1 10.1038/S41586-021-03721-X 2021-07-07
8I9A C3AR C3a Complement peptide A (Rhodopsin) Human N/A 0 1 0 0 8I9A 3.6 10.1016/J.CELL.2023.09.020 2023-10-18
5DGY OPSD Rhodopsin Opsins A (Rhodopsin) Human in meso/LCP 4 0 0 7 5DGY 7.7 10.1038/SDATA.2016.21 2016-03-23
8IA7 GASR CCK2 Cholecystokinin A (Rhodopsin) Human N/A 0 0 0 0 8IA7 3.1 10.1038/S41421-022-00420-3 2023-12-06
8K5D HCAR2 HCA2 Hydroxycarboxylic acid A (Rhodopsin) Human N/A 0 0 0 0 8K5D 3.7 10.1038/S41467-023-42764-8 2023-11-22
8IJB HCAR2 HCA2 Hydroxycarboxylic acid A (Rhodopsin) Human N/A 0 2 0 0 8IJB 3.2 10.1038/S41421-023-00610-7 2024-01-03
8HTI O52E4 OR52E4 Odorant family 52 O1 (fish-like odorant) Human N/A 0 1 0 0 8HTI 3.0 10.1038/S41467-023-43983-9 2023-12-20
8HNN CXCR3 CXCR3 Chemokine A (Rhodopsin) Human N/A 0 2 0 0 8HNN 3.6 10.1038/S41594-023-01175-5 2023-11-29
8HN1 ADA1A α1A Adrenoceptors A (Rhodopsin) Human N/A 0 2 0 0 8HN1 2.9 2023-12-20
8GDC PE2R3 EP3 Prostanoid A (Rhodopsin) Human N/A 0 0 0 0 8GDC 3.5 10.1073/PNAS.2216329120 2024-01-10
8G05 GPR84 GPR84 A orphans A (Rhodopsin) Human N/A 0 1 0 0 8G05 3.0 10.1038/S41467-023-41201-0 2023-11-01
6X19 GLP1R GLP-1 Glucagon B1 (Secretin) Human N/A 0 1 0 0 6X19 2.1 10.1016/J.MOLCEL.2020.09.020 2020-09-09
7CKX DRD1 D1 Dopamine A (Rhodopsin) Human N/A 0 0 0 0 7CKX 3.5 10.1016/J.CELL.2021.01.028 2021-03-03
6XBL SMO SMO Frizzled F (Frizzled) Human N/A 0 1 0 0 6XBL 3.9 10.1038/S41589-020-0646-2 2020-09-30
7D3S SCTR secretin Glucagon B1 (Secretin) Human N/A 0 1 0 0 7D3S 2.9 10.1016/J.BBRC.2020.08.042 2020-11-04
7LJC DRD1 D1 Dopamine A (Rhodopsin) Human N/A 0 0 0 0 7LJC 3.0 10.1038/S41422-021-00482-0 2021-03-03
7L0Q NTR1 NTS1 Neurotensin A (Rhodopsin) Rat N/A 1 3 0 0 7L0Q 4.3 10.1038/S41594-020-00554-6 2021-01-06
7JV5 DRD1 D1 Dopamine A (Rhodopsin) Human N/A 0 0 0 0 7JV5 3.0 10.1016/J.CELL.2021.01.027 2021-02-24
5D5A ADRB2 β2 Adrenoceptors A (Rhodopsin) Human in meso/LCP 3 2 0 2 5D5A 2.5 10.1107/S2059798315021683 2016-01-13
6VI4 OPRK κ Opioid A (Rhodopsin) Human N/A 1 2 0 1 6VI4 3.3 10.1038/S41467-020-14889-7 2020-03-18
7MTR GRM2 mGlu2 Metabotropic glutamate C (Glutamate) Human N/A 0 1 0 0 7MTR 3.3 10.1038/S41586-021-03680-3 2021-07-07
4LDE ADRB2 β2 Adrenoceptors A (Rhodopsin) Human in meso/LCP 4 3 0 3 4LDE 2.8 10.1038/NATURE12572 2013-09-25
5UNG AGTR2 AT2 Angiotensin A (Rhodopsin) Human in meso/LCP 0 2 0 6 5UNG 2.8 10.1038/NATURE22035 2017-04-05
6OL9 ACM5 M5 Acetylcholine (muscarinic) A (Rhodopsin) Human N/A 0 2 0 3 6OL9 2.5 10.1073/PNAS.1914446116 2019-12-11
7D76 AGRG3 ADGRG3 ADGRG B2 (Adhesion) Human N/A 0 2 0 0 7D76 3.1 10.1038/S41586-020-03083-W 2021-02-03
6PEL OPSD Rhodopsin Opsins A (Rhodopsin) Bovine N/A 0 0 0 0 6PEL 3.2 2020-06-24
6XBM SMO SMO Frizzled F (Frizzled) Human N/A 0 1 0 0 6XBM 3.2 10.1038/S41589-020-0646-2 2020-09-30
6XOX GLP1R GLP-1 Glucagon B1 (Secretin) Human N/A 0 2 0 0 6XOX 3.1 10.1073/PNAS.2014879117 2020-11-18
5ZKP PTAFR PAF Platelet-activating factor A (Rhodopsin) Human N/A 5 3 0 4 5ZKP 2.8 10.1038/S41594-018-0068-Y 2018-06-20
7L1U OX2R OX2 Orexin A (Rhodopsin) Human N/A 0 3 0 0 7L1U 3.2 10.1038/S41467-021-21087-6 2021-02-10
7YXA S1PR5 S1P5 Lysophospholipid (S1P) A (Rhodopsin) Human N/A 0 2 0 0 7YXA 2.2 10.1038/S41467-022-32447-1 2022-08-10
8WKY MC4R MC4 Melanocortin A (Rhodopsin) Human N/A 0 3 0 0 8WKY 2.9 10.1021/ACS.JMEDCHEM.3C01822 2024-08-07
6LFO CXCR2 CXCR2 Chemokine A (Rhodopsin) Human N/A 0 0 0 0 6LFO 3.4 10.1038/S41586-020-2492-5 2020-09-02
7D77 AGRG3 ADGRG3 ADGRG B2 (Adhesion) Human N/A 0 2 0 0 7D77 2.9 10.1038/S41586-020-03083-W 2021-02-03
7BZ2 ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 1 0 0 7BZ2 3.8 10.1038/S41421-020-0176-9 2020-08-05
7CMU DRD3 D3 Dopamine A (Rhodopsin) Human N/A 0 0 0 0 7CMU 3.0 10.1016/J.MOLCEL.2021.01.003 2021-03-10
6MXT ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 1 3 0 1 6MXT 3.0 10.1038/s41589-018-0145-x 2018-11-14
7CKZ DRD1 D1 Dopamine A (Rhodopsin) Human N/A 0 0 0 0 7CKZ 3.1 10.1016/J.CELL.2021.01.028 2021-03-03
6VCB GLP1R GLP-1 Glucagon B1 (Secretin) Human N/A 0 2 0 0 6VCB 3.3 10.1038/S41589-020-0589-7 2020-07-22
7DHI ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 1 2 0 0 7DHI 3.3 10.1093/NSR/NWAA284 2020-12-16
7LJD DRD1 D1 Dopamine A (Rhodopsin) Human N/A 0 0 0 0 7LJD 3.2 2021-03-03
6WGT 5HT2A 5-HT2A 5-Hydroxytryptamine A (Rhodopsin) Human N/A 0 3 0 0 6WGT 3.4 10.1016/J.CELL.2020.08.024 2020-09-23
7D68 GLP2R GLP-2 Glucagon B1 (Secretin) Human N/A 0 1 0 0 7D68 3.0 10.1038/S41422-020-00442-0 2020-12-16
6WI9 SCTR secretin Glucagon B1 (Secretin) Human N/A 0 1 0 0 6WI9 4.3 10.1038/S41467-020-17791-4 2020-08-12
7AD3 STE2 STE2 STE2 D1 (Ste2-like fungal pheromone) strain ATCC 204508 / S288c N/A 0 1 0 0 7AD3 3.5 10.1038/S41586-020-2994-1 2020-12-09
6C1Q C5AR1 C5a1 Complement peptide A (Rhodopsin) Human in meso/LCP 0 2 0 4 6C1Q 2.9 10.1038/S41594-018-0067-Z 2018-05-30
7WC6 5HT2A 5-HT2A 5-Hydroxytryptamine A (Rhodopsin) Human N/A 0 3 0 0 7WC6 2.6 10.1126/SCIENCE.ABL8615 2022-01-26
7SK8 ACKR3 ACKR3 Chemokine A (Rhodopsin) Human N/A 0 1 0 0 7SK8 3.3 10.1126/SCIADV.ABN8063 2022-07-27
6XBJ SMO SMO Frizzled F (Frizzled) Human N/A 0 1 0 0 6XBJ 3.9 2020-09-30
8WKZ MC4R MC4 Melanocortin A (Rhodopsin) Human N/A 0 3 0 0 8WKZ 3.3 10.1021/ACS.JMEDCHEM.3C01822 2024-08-07
3ZPR ADRB1 β1 Adrenoceptors A (Rhodopsin) Wild turkey vapour diffusion 8 3 0 1 3ZPR 2.7 10.1021/jm400140q 2013-04-03
6X1A GLP1R GLP-1 Glucagon B1 (Secretin) Human N/A 0 1 0 0 6X1A 2.5 10.1016/J.MOLCEL.2020.09.020 2020-09-09
8WMA FZD4 FZD4 Frizzled F (Frizzled) Human N/A 0 0 0 0 8WMA 3.5 10.1038/S41467-024-52174-Z 2024-09-11
6M1I PACR PAC1 VIP and PACAP B1 (Secretin) Human N/A 0 2 0 0 6M1I 3.5 10.1038/S41422-020-0280-2 2020-03-11
5YC8 ACM2 M2 Acetylcholine (muscarinic) A (Rhodopsin) Human N/A 0 2 0 5 5YC8 2.5 10.1038/S41589-018-0152-Y 2018-11-21
5V54 5HT1B 5-HT1B 5-Hydroxytryptamine A (Rhodopsin) Human in meso/LCP 1 2 0 5 5V54 3.9 2018-02-07
7C7Q GABR2 GABAB2 GABAB C (Glutamate) Human N/A 0 2 0 0 7C7Q 3.0 2020-07-01
7CFM GPBAR GPBA Bile acid A (Rhodopsin) Human N/A 0 0 0 0 7CFM 3.0 10.1038/S41586-020-2569-1 2020-09-09
7JVP DRD1 D1 Dopamine A (Rhodopsin) Human N/A 0 0 0 0 7JVP 2.9 10.1016/J.CELL.2021.01.027 2021-02-24
8W1V ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 1 1 0 0 8W1V 3.0 2024-07-17
7L0R NTR1 NTS1 Neurotensin A (Rhodopsin) Rat N/A 1 3 0 0 7L0R 4.2 10.1038/S41594-020-00554-6 2021-01-06
5D5B ADRB2 β2 Adrenoceptors A (Rhodopsin) Human in meso/LCP 3 2 0 2 5D5B 3.8 2016-01-13
6HLL NK1R NK1 Tachykinin A (Rhodopsin) Human N/A 0 2 0 1 6HLL 3.3 10.1038/S41467-018-07939-8 2019-01-16
7JVR DRD2 D2 Dopamine A (Rhodopsin) Human N/A 0 0 0 0 7JVR 2.8 10.1016/J.CELL.2021.01.027 2021-02-24
3KJ6 ADRB2 β2 Adrenoceptors A (Rhodopsin) Human vapour diffusion 3 2 0 3 3KJ6 3.4 10.1038/NATURE08650 2010-02-16
6LN2 GLP1R GLP-1 Glucagon B1 (Secretin) Human N/A 0 3 0 1 6LN2 3.2 10.1038/S41467-020-14934-5 2020-03-18
7BW0 GPBAR GPBA Bile acid A (Rhodopsin) Human N/A 0 2 0 0 7BW0 3.9 10.1038/S41392-020-00262-Z 2020-09-02
7L0P NTR1 NTS1 Neurotensin A (Rhodopsin) Rat N/A 1 3 0 0 7L0P 4.1 10.1038/S41594-020-00554-6 2021-01-06
6PH7 OPSD Rhodopsin Opsins A (Rhodopsin) Bovine N/A 0 0 0 0 6PH7 2.9 2020-07-01
8CU6 AA2AR A2A Adenosine A (Rhodopsin) Human N/A 0 3 0 0 8CU6 2.8 10.1021/acs.jmedchem.2c00462 2022-08-31
7JVQ DRD1 D1 Dopamine A (Rhodopsin) Human N/A 0 0 0 0 7JVQ 3.0 10.1016/J.CELL.2021.01.027 2021-02-24
5K2C AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 0 3 0 4 5K2C 1.9 10.1126/SCIADV.1600292 2016-09-21
7CKW DRD1 D1 Dopamine A (Rhodopsin) Human N/A 0 0 0 0 7CKW 3.2 10.1016/J.CELL.2021.01.028 2021-03-03
7CFN GPBAR GPBA Bile acid A (Rhodopsin) Human N/A 0 0 0 0 7CFN 3.0 10.1038/S41586-020-2569-1 2020-09-09
6WHC GLR glucagon Glucagon B1 (Secretin) Human N/A 0 0 0 0 6WHC 3.4 10.1074/JBC.RA120.013793 2020-05-27
7E2X 5HT1A 5-HT1A 5-Hydroxytryptamine A (Rhodopsin) Human N/A 0 1 0 0 7E2X 3.0 10.1038/S41586-021-03376-8 2021-04-14
7CKY DRD1 D1 Dopamine A (Rhodopsin) Human N/A 0 0 0 0 7CKY 3.2 10.1016/J.CELL.2021.01.028 2021-03-03
6X18 GLP1R GLP-1 Glucagon B1 (Secretin) Human N/A 0 1 0 0 6X18 2.1 10.1016/J.MOLCEL.2020.09.020 2020-09-09
7DHR ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 1 2 0 0 7DHR 3.8 2020-12-16
6KQI CNR1 CB1 Cannabinoid A (Rhodopsin) Human N/A 0 3 0 3 6KQI 3.3 10.1038/S41589-019-0387-2 2019-10-23
6LI3 GPR52 GPR52 A orphans A (Rhodopsin) Human N/A 0 1 0 0 6LI3 3.3 10.1038/S41586-020-2019-0 2020-02-26
7ZI0 SMO SMO Frizzled F (Frizzled) Human N/A 0 3 0 0 7ZI0 3.0 10.1126/SCIADV.ABM5563 2022-06-15
7C2E GLP1R GLP-1 Glucagon B1 (Secretin) Human N/A 0 1 0 0 7C2E 4.2 10.1038/S41422-020-0384-8 2020-08-26
8FD0 OPSD Rhodopsin Opsins A (Rhodopsin) Bovine N/A 0 0 0 0 8FD0 3.7 10.1038/S41467-023-40911-9 2023-08-30
5MZP AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 9 3 0 4 5MZP 2.1 10.1016/j.str.2017.06.012 2017-07-26
8A2O AA2AR A2A Adenosine A (Rhodopsin) Human N/A 0 3 0 0 8A2O 3.5 10.1107/S1600576723006428 2023-08-30
3VW7 PAR1 PAR1 Proteinase-activated A (Rhodopsin) Human in meso/LCP 2 3 0 5 3VW7 2.2 10.1038/NATURE11701 2012-12-12
6DRX 5HT2B 5-HT2B 5-Hydroxytryptamine A (Rhodopsin) Human N/A 1 3 0 2 6DRX 3.1 10.1038/s41594-018-0116-7 2018-08-29
7S15 GLP1R GLP-1 Glucagon B1 (Secretin) Human N/A 0 2 0 0 7S15 3.8 10.1021/acs.jmedchem.1c01856 2022-06-08
8IW9 TAAR9 TAAR9 A orphans A (Rhodopsin) Mouse N/A 0 0 0 0 8IW9 3.1 10.1038/S41586-023-06106-4 2023-05-31
7RKN US28 US28 Unclassified A (Rhodopsin) strain AD169 N/A 0 0 0 0 7RKN 3.6 10.1126/SCIADV.ABL5442 2022-01-26
7X5H 5HT5A 5-HT5A 5-Hydroxytryptamine A (Rhodopsin) Human N/A 0 1 0 0 7X5H 3.1 10.1038/S41421-022-00412-3 2022-09-14
2G87 OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 0 0 0 0 2G87 2.6 10.1002/ANIE.200600595 2006-09-02
7XW9 TRFR TRH1 Thyrotropin-releasing hormone A (Rhodopsin) Human N/A 0 0 0 0 7XW9 2.7 2022-12-28
3C9M OPSD Rhodopsin Opsins A (Rhodopsin) Bovine NA 2 0 0 0 3C9M 3.4 10.1107/S0907444908017162 2008-08-05
8GGR ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8GGR 3.4 10.1038/S41586-024-07153-1 2024-03-06
8X64 HRH1 H1 Histamine A (Rhodopsin) Human N/A 0 3 0 0 8X64 3.4 10.1038/S41467-023-44477-4 2024-01-17
9IJD ADRB3 β3 Adrenoceptors A (Rhodopsin) Human N/A 0 2 0 0 9IJD 2.8 10.1002/CPLU.202400288 2024-08-21
7RYC OXYR OT Vasopressin and oxytocin A (Rhodopsin) Human N/A 0 0 0 0 7RYC 2.9 10.1038/S41594-022-00728-4 2022-03-09
8JHC FZD3 FZD3 Frizzled F (Frizzled) Human N/A 0 3 0 0 8JHC 3.3 10.1038/S41421-023-00627-Y 2024-01-17
8T3S FFAR2 FFA2 Free fatty acid A (Rhodopsin) Human N/A 0 2 0 0 8T3S 3.1 10.1126/SCIADV.ADJ2384 2024-01-24
8YY8 FZD7 FZD7 Frizzled F (Frizzled) Human N/A 0 1 0 0 8YY8 3.2 10.1038/S41422-021-00525-6 2024-04-24
7YS6 5HT6R 5-HT6 5-Hydroxytryptamine A (Rhodopsin) Human N/A 0 3 0 0 7YS6 3.0 2023-03-29
4NC3 5HT2B 5-HT2B 5-Hydroxytryptamine A (Rhodopsin) Human in meso/LCP 1 3 0 5 4NC3 2.8 10.1126/SCIENCE.1244142 2013-12-18
8JIS GLP1R GLP-1 Glucagon B1 (Secretin) Human N/A 0 2 0 0 8JIS 2.5 10.1073/PNAS.2303696120 2023-11-08
7Y66 C5AR1 C5a1 Complement peptide A (Rhodopsin) Human N/A 0 1 0 0 7Y66 2.9 10.1038/S41422-023-00779-2 2023-03-01
6FK9 OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 2 0 0 0 6FK9 2.6 10.1073/PNAS.1718084115 2018-04-04
6KNM APJ apelin Apelin A (Rhodopsin) Human N/A 0 3 0 3 6KNM 3.2 10.1126/SCIADV.AAX7379 2020-01-29
8GEG ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8GEG 3.8 10.1038/S41586-024-07153-1 2024-03-06
7WI8 GRM3 mGlu3 Metabotropic glutamate C (Glutamate) Human N/A 0 1 0 0 7WI8 4.2 10.1038/S41422-022-00623-Z 2022-03-16
7SK3 ACKR3 ACKR3 Chemokine A (Rhodopsin) Human N/A 0 1 0 0 7SK3 3.8 10.1126/SCIADV.ABN8063 2022-07-27
7E33 5HT1E 5-HT1E 5-Hydroxytryptamine A (Rhodopsin) Human N/A 0 1 0 0 7E33 2.9 10.1038/S41586-021-03376-8 2021-04-14
8GGU ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8GGU 3.4 10.1038/S41586-024-07153-1 2024-03-06
8IRT DRD3 D3 Dopamine A (Rhodopsin) Human N/A 0 0 0 0 8IRT 2.7 10.1038/S41422-023-00808-0 2023-06-07
6ME9 MTR1B MT2 Melatonin A (Rhodopsin) Human N/A 0 3 0 3 6ME9 3.3 10.1038/S41586-019-1144-0 2019-04-24
8U4P CXCR4 CXCR4 Chemokine A (Rhodopsin) Human N/A 0 1 0 0 8U4P 3.2 10.1038/S41594-024-01397-1 2024-03-13
7MTB OPSD Rhodopsin Opsins A (Rhodopsin) Bovine N/A 0 0 0 0 7MTB 4.0 10.1038/S41586-021-03721-X 2021-07-07
8J22 FFAR2 FFA2 Free fatty acid A (Rhodopsin) Human N/A 0 1 0 0 8J22 3.2 10.1038/S41422-023-00914-Z 2024-01-24
5K2D AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 0 3 0 4 5K2D 1.9 10.1126/SCIADV.1600292 2016-09-21
8X3L CNR2 CB2 Cannabinoid A (Rhodopsin) Human N/A 0 1 0 0 8X3L 3.1 10.1073/PNAS.2401091121 2024-11-20
8UNW ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8UNW 3.4 10.1038/S41586-024-07153-1 2024-03-06
8IHI HCAR2 HCA2 Hydroxycarboxylic acid A (Rhodopsin) Human N/A 0 1 0 0 8IHI 3.1 10.1038/S41467-023-41650-7 2023-08-30
7CRH DRD1 D1 Dopamine A (Rhodopsin) Human N/A 0 0 0 0 7CRH 3.3 10.1016/J.CELL.2021.01.028 2021-03-03
5EN0 OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 3 0 0 0 5EN0 2.8 10.15252/EMBR.201642671 2016-08-10
8WGC GRM2 mGlu2 Metabotropic glutamate C (Glutamate) Human N/A 0 1 0 0 8WGC 6.0 10.1038/S41467-024-54744-7 2024-11-27
7WC9 5HT2A 5-HT2A 5-Hydroxytryptamine A (Rhodopsin) Human N/A 0 3 0 0 7WC9 2.5 10.1126/SCIENCE.ABL8615 2022-01-26
8WVX LGR4 LGR4 A orphans A (Rhodopsin) Human N/A 0 2 0 0 8WVX 3.3 2024-10-30
8GG1 ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8GG1 3.0 10.1038/S41586-024-07153-1 2024-03-06
6E3Y CALRL calcitonin-like Calcitonin B1 (Secretin) Human N/A 0 1 0 2 6E3Y 3.3 10.1038/S41586-018-0535-Y 2018-09-19
7EJX GPR88 GPR88 A orphans A (Rhodopsin) Human N/A 0 0 0 0 7EJX 2.4 10.1038/S41467-022-30081-5 2022-04-13
5N2R AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 9 3 0 4 5N2R 2.8 10.1016/j.str.2017.06.012 2017-07-26
8WSS MCHR1 MCH1 Melanin-concentrating hormone A (Rhodopsin) Human N/A 0 2 0 0 8WSS 3.0 10.1038/S41421-024-00679-8 2024-06-19
5L7D SMO SMO Frizzled F (Frizzled) Human in meso/LCP 1 3 0 2 5L7D 3.2 10.1038/NATURE18934 2016-07-20
4Z34 LPAR1 LPA1 Lysophospholipid (LPA) A (Rhodopsin) Human in meso/LCP 0 3 0 5 4Z34 3.0 10.1016/J.CELL.2015.06.002 2015-06-03
7C6A AGTR2 AT2 Angiotensin A (Rhodopsin) Human N/A 0 3 0 0 7C6A 3.4 10.1038/S41598-020-68355-X 2020-07-29
2YCX ADRB1 β1 Adrenoceptors A (Rhodopsin) Wild turkey vapour diffusion 8 4 0 1 2YCX 3.3 2011-06-01
5NLX AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 9 3 0 4 5NLX 2.1 10.1038/S41467-017-00630-4 2017-09-27
8HMV GPR21 GPR21 A orphans A (Rhodopsin) Human N/A 0 2 0 0 8HMV 2.9 10.1002/MCO2.205 2023-03-01
7VUG GP139 GPR139 A orphans A (Rhodopsin) Human N/A 0 2 0 0 7VUG 3.2 10.1038/S41422-021-00591-W 2021-12-29
8X8N SSR5 SST5 Somatostatin A (Rhodopsin) Human N/A 0 0 0 0 8X8N 2.9 2024-06-12
7RG9 GLP1R GLP-1 Glucagon B1 (Secretin) Human N/A 0 2 0 0 7RG9 3.2 10.1073/PNAS.2116506119 2022-04-13
8W8A TAAR1 TA1 Trace amine A (Rhodopsin) Human N/A 0 0 0 0 8W8A 2.8 10.1038/S41586-023-06775-1 2023-11-22
6LPB PACR PAC1 VIP and PACAP B1 (Secretin) Human N/A 0 2 0 1 6LPB 3.9 10.1038/S41594-020-0386-8 2020-03-11
5WIU DRD4 D4 Dopamine A (Rhodopsin) Human in meso/LCP 0 1 0 5 5WIU 2.0 10.1126/SCIENCE.AAN5468 2017-10-18
5TVN 5HT2B 5-HT2B 5-Hydroxytryptamine A (Rhodopsin) Human in meso/LCP 1 3 0 5 5TVN 2.9 10.1016/J.CELL.2016.12.033 2017-02-01
7D7M PE2R4 EP4 Prostanoid A (Rhodopsin) Human N/A 0 3 0 0 7D7M 3.3 10.1016/J.STR.2020.11.007 2020-11-18
9EPO FZD7 FZD7 Frizzled F (Frizzled) Human N/A 0 1 0 0 9EPO 1.9 2024-10-02
8YN6 HRH3 H3 Histamine A (Rhodopsin) Human N/A 0 0 0 0 8YN6 2.8 10.1038/S41467-024-52585-Y 2024-10-09
8YKV SUCR1 succinate Succinate A (Rhodopsin) Human N/A 0 0 0 0 8YKV 2.5 2024-05-29
4A4M OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 3 0 0 0 4A4M 3.3 10.1073/PNAS.1114089108 2012-01-25
6PT3 OPRD δ Opioid A (Rhodopsin) Human N/A 0 2 0 0 6PT3 3.3 10.1126/SCIADV.AAX9115 2019-12-11
7U2K OPRM μ Opioid A (Rhodopsin) Mouse N/A 0 2 0 0 7U2K 3.3 10.1038/S41586-022-05588-Y 2022-12-07
7YU4 LPAR1 LPA1 Lysophospholipid (LPA) A (Rhodopsin) Human N/A 0 1 0 0 7YU4 3.3 10.1038/S41467-022-33121-2 2022-10-05
7TMW RXFP1 RXFP1 Relaxin family peptide A (Rhodopsin) Human N/A 0 1 0 0 7TMW 3.2 2023-02-15
7T9M TSHR TSH Glycoprotein hormone A (Rhodopsin) Human N/A 0 1 0 0 7T9M 3.1 10.1038/S41586-022-05159-1 2022-08-10
7UL3 HRH2 H2 Histamine A (Rhodopsin) Human N/A 0 1 0 0 7UL3 3.0 10.1038/S41594-022-00859-8 2022-06-29
5YWY PE2R4 EP4 Prostanoid A (Rhodopsin) Human N/A 0 3 0 2 5YWY 3.2 10.1038/S41589-018-0131-3 2018-12-05
7L1V OX2R OX2 Orexin A (Rhodopsin) Human N/A 0 3 0 0 7L1V 3.0 10.1038/S41467-021-21087-6 2021-02-10
7MT8 OPSD Rhodopsin Opsins A (Rhodopsin) Bovine N/A 0 0 0 0 7MT8 5.8 10.1038/S41586-021-03721-X 2021-07-07
4BVN ADRB1 β1 Adrenoceptors A (Rhodopsin) Wild turkey in meso/LCP 11 3 0 1 4BVN 2.1 10.1371/JOURNAL.PONE.0092727 2014-04-02
5L7I SMO SMO Frizzled F (Frizzled) Human in meso/LCP 1 3 0 2 5L7I 3.3 10.1038/NATURE18934 2016-07-20
8UHB TAAR1 TA1 Trace amine A (Rhodopsin) Human N/A 0 0 0 0 8UHB 3.4 10.1038/S41467-023-44601-4 2024-01-10
7Y27 SSR2 SST2 Somatostatin A (Rhodopsin) Human N/A 0 1 0 0 7Y27 3.5 10.1038/S41589-022-01130-3 2022-10-19
4GPO ADRB1 β1 Adrenoceptors A (Rhodopsin) Wild turkey vapour diffusion 8 4 0 2 4GPO 3.5 10.1038/NSMB.2504 2013-02-27
7W3Z GRPR BB2 Bombesin A (Rhodopsin) Human N/A 0 2 0 0 7W3Z 3.0 2023-02-22
8FLU PTH1R PTH1 Parathyroid hormone B1 (Secretin) Human N/A 0 1 0 0 8FLU 2.8 10.1016/J.STR.2023.04.002 2023-04-26
8IRU DRD4 D4 Dopamine A (Rhodopsin) Human N/A 0 1 0 0 8IRU 3.2 10.1038/S41422-023-00808-0 2023-06-21
6FKB OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 2 1 0 0 6FKB 3.0 10.1073/PNAS.1718084115 2018-04-04
7WC5 5HT2A 5-HT2A 5-Hydroxytryptamine A (Rhodopsin) Human N/A 0 3 0 0 7WC5 3.2 10.1126/SCIENCE.ABL8615 2022-01-26
3OE0 CXCR4 CXCR4 Chemokine A (Rhodopsin) Human in meso/LCP 2 3 0 6 3OE0 2.9 2010-10-27
8DPI 5HT2C 5-HT2C 5-Hydroxytryptamine A (Rhodopsin) Human N/A 0 0 0 0 8DPI 3.4 10.1016/J.CELREP.2022.111211 2022-08-24
5WQC OX2R OX2 Orexin A (Rhodopsin) Human in meso/LCP 1 3 0 4 5WQC 2.0 10.1016/J.STR.2017.11.005 2017-11-29
5W0P OPSD Rhodopsin Opsins A (Rhodopsin) Human in meso/LCP 5 0 0 7 5W0P 3.0 10.1016/J.CELL.2017.07.002 2017-08-09
7EO4 S1PR1 S1P1 Lysophospholipid (S1P) A (Rhodopsin) Human N/A 0 0 0 0 7EO4 2.9 10.1038/S41589-021-00930-3 2022-01-05
8ITF TAAR9 TAAR9 A orphans A (Rhodopsin) Mouse N/A 0 0 0 0 8ITF 3.5 10.1038/S41586-023-06106-4 2023-05-31
6TP6 OX1R OX1 Orexin A (Rhodopsin) Human N/A 0 2 0 2 6TP6 2.3 10.1021/acs.jmedchem.9b01787 2020-01-01
5OLZ AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 9 3 0 3 5OLZ 1.9 10.1038/S41598-017-18570-W 2018-01-17
9C2F CASR CaS Calcium-sensing C (Glutamate) Human N/A 0 2 0 0 9C2F 2.8 2024-10-02
7E14 GLP1R GLP-1 Glucagon B1 (Secretin) Human N/A 0 1 0 0 7E14 2.9 10.1038/S41467-021-24058-Z 2021-07-07
5K2A AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 0 3 0 4 5K2A 2.5 10.1126/SCIADV.1600292 2016-09-21
4PY0 P2Y12 P2Y12 P2Y A (Rhodopsin) Human in meso/LCP 1 1 0 5 4PY0 3.1 2014-04-30
7X9C NPY4R Y4 Neuropeptide Y A (Rhodopsin) Human N/A 0 1 0 0 7X9C 3.0 10.1126/SCIADV.ABM1232 2022-05-18
8F7W OPRK κ Opioid A (Rhodopsin) Human N/A 0 1 0 0 8F7W 3.2 10.1016/J.CELL.2022.12.026 2022-12-14
7XKE AGRG2 ADGRG2 ADGRG B2 (Adhesion) Mouse N/A 0 2 0 0 7XKE 2.9 10.1038/S41589-022-01084-6 2022-08-10
8JXR DRD1 D1 Dopamine A (Rhodopsin) Human N/A 0 2 0 0 8JXR 3.6 10.1016/J.NEURON.2024.07.003 2024-09-04
8U4R CXCR4 CXCR4 Chemokine A (Rhodopsin) Human N/A 0 1 0 0 8U4R 3.1 10.1038/S41594-024-01397-1 2024-03-13
8KEX MRGX4 MRGPRX4 A orphans A (Rhodopsin) Human N/A 0 0 0 0 8KEX 3.2 10.1016/J.CELL.2024.10.001 2024-11-06
7Y13 MRGRD MRGPRD A orphans A (Rhodopsin) Human N/A 0 1 0 0 7Y13 3.1 10.1038/S42003-022-03668-3 2022-07-20
8WC5 TAAR1 TA1 Trace amine A (Rhodopsin) Mouse N/A 0 0 0 0 8WC5 3.3 10.1016/J.CELL.2023.10.014 2023-12-27
6E67 ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 1 2 0 4 6E67 3.7 10.1016/J.CELL.2019.04.021 2019-06-05
7F1S CCR5 CCR5 Chemokine A (Rhodopsin) Human N/A 1 2 0 0 7F1S 2.8 10.1038/S41467-021-24438-5 2021-07-14
7XY7 AA2BR A2B Adenosine A (Rhodopsin) Human N/A 0 1 0 0 7XY7 3.3 10.1126/SCIADV.ADD3709 2023-05-03
5OLO AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 9 3 0 4 5OLO 3.1 10.1038/S41598-017-18570-W 2018-01-17
8VY9 T2R14 TAS2R14 Taste 2 T2 (Taste 2) Human N/A 0 0 0 0 8VY9 2.9 2024-04-03
5C1M OPRM μ Opioid A (Rhodopsin) Mouse in meso/LCP 0 2 0 4 5C1M 2.1 10.1038/NATURE14886 2015-08-05
6ORV GLP1R GLP-1 Glucagon B1 (Secretin) Human N/A 0 1 0 0 6ORV 3.0 10.1038/s41586-019-1902-z 2020-01-08
7RMH NK1R NK1 Tachykinin A (Rhodopsin) Human N/A 0 0 0 0 7RMH 3.1 10.1038/S41589-021-00890-8 2021-11-03
5UIW CCR5 CCR5 Chemokine A (Rhodopsin) Human in meso/LCP 4 3 0 5 5UIW 2.2 10.1016/J.IMMUNI.2017.05.002 2017-06-28
8GGI ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8GGI 3.5 10.1038/S41586-024-07153-1 2024-03-06
7TRY CRFR2 CRF2 Corticotropin-releasing factor B1 (Secretin) Human N/A 0 2 0 0 7TRY 3.7 10.1038/S41467-022-33851-3 2022-11-09
7DFL HRH1 H1 Histamine A (Rhodopsin) Human N/A 0 0 0 0 7DFL 3.3 10.1038/S41467-021-22427-2 2021-03-31
7TYY CALCR CT Calcitonin B1 (Secretin) Human N/A 0 1 0 0 7TYY 3.0 10.1126/SCIENCE.ABM9609 2022-03-23
7XOV CCKAR CCK1 Cholecystokinin A (Rhodopsin) Human N/A 0 0 0 0 7XOV 3.0 10.1038/S41421-022-00420-3 2022-07-20
4XT1 US28 US28 Unclassified A (Rhodopsin) strain AD169 in meso/LCP 0 2 0 1 4XT1 2.9 10.1126/SCIENCE.AAA5026 2015-03-04
8JPB NTR1 NTS1 Neurotensin A (Rhodopsin) Human N/A 0 0 0 0 8JPB 3.1 10.1038/S41586-023-06395-9 2023-08-09
8K4N GPR34 GPR34 A orphans A (Rhodopsin) Human N/A 0 2 0 0 8K4N 2.8 2023-10-25
8FEG OPRK κ Opioid A (Rhodopsin) Human N/A 0 2 0 0 8FEG 2.5 10.1038/s41467-023-43718-w 2023-12-06
8T3Q FFAR4 FFA4 Free fatty acid A (Rhodopsin) Human N/A 0 2 0 0 8T3Q 3.1 10.1126/SCIADV.ADJ2384 2024-01-24
8XBG GPR34 GPR34 A orphans A (Rhodopsin) Human N/A 0 1 0 0 8XBG 3.4 10.1038/S41467-024-45046-Z 2024-05-15
7EUO FPR1 FPR1 Formylpeptide A (Rhodopsin) Human N/A 0 0 0 0 7EUO 2.9 10.1038/S41467-022-32822-Y 2022-05-25
8J6J HCAR2 HCA2 Hydroxycarboxylic acid A (Rhodopsin) Human N/A 0 1 0 0 8J6J 2.8 10.1016/J.CELREP.2023.113406 2024-01-10
5XPR EDNRB ETB Endothelin A (Rhodopsin) Human in meso/LCP 7 3 0 7 5XPR 3.6 10.1038/NSMB.3450 2017-08-16
8FLT PTH1R PTH1 Parathyroid hormone B1 (Secretin) Human N/A 0 1 0 0 8FLT 3.0 10.1016/J.STR.2023.04.002 2023-04-26
7DFP DRD2 D2 Dopamine A (Rhodopsin) Human N/A 0 2 0 0 7DFP 3.1 10.1038/S41467-020-20221-0 2020-12-30
6VMS DRD2 D2 Dopamine A (Rhodopsin) Human N/A 0 2 0 0 6VMS 3.8 10.1038/S41586-020-2379-5 2020-06-17
4N4W SMO SMO Frizzled F (Frizzled) Human in meso/LCP 0 2 0 5 4N4W 2.8 10.1038/NCOMMS5355 2014-01-22
5TZR FFAR1 FFA1 Free fatty acid A (Rhodopsin) Human in meso/LCP 4 1 0 6 5TZR 2.2 10.1038/NSMB.3417 2017-06-07
8JD5 GRM2 mGlu2 Metabotropic glutamate C (Glutamate) Human N/A 0 1 0 0 8JD5 3.6 10.1038/S41422-023-00830-2 2023-06-21
6LMK GLR glucagon Glucagon B1 (Secretin) Human N/A 0 2 0 1 6LMK 3.7 10.1126/SCIENCE.AAZ5346 2020-04-01
5V57 SMO SMO Frizzled F (Frizzled) Human in meso/LCP 0 3 0 6 5V57 3.0 10.1038/NCOMMS15383 2017-05-24
8GG6 ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8GG6 3.3 10.1038/S41586-024-07153-1 2024-03-06
6H7N ADRB1 β1 Adrenoceptors A (Rhodopsin) Wild turkey N/A 6 3 0 2 6H7N 2.5 10.1101/436212 2018-10-17
7TYL CALCR CT Calcitonin B1 (Secretin) Human N/A 0 1 0 0 7TYL 3.3 10.1126/SCIENCE.ABM9609 2022-03-23
9CBL ADA2A α2A Adrenoceptors A (Rhodopsin) Human N/A 0 3 0 0 9CBL 2.8 10.1038/S12276-024-01296-X 2024-09-11
8WWH MCHR1 MCH1 Melanin-concentrating hormone A (Rhodopsin) Human N/A 0 1 0 0 8WWH 2.8 2024-11-13
6ZIN NTR1 NTS1 Neurotensin A (Rhodopsin) Rat N/A 1 1 0 0 6ZIN 2.6 10.1126/sciadv.abe5504 2021-02-10
7PIU MC4R MC4 Melanocortin A (Rhodopsin) Human N/A 0 0 0 0 7PIU 2.6 10.1038/S41422-021-00569-8 2021-11-17
8XOF GPER1 GPER Estrogen (G protein-coupled) A (Rhodopsin) Human N/A 0 0 0 0 8XOF 2.6 2024-04-10
7WUJ AGRG4 ADGRG4 ADGRG B2 (Adhesion) Human N/A 0 1 0 0 7WUJ 3.3 10.1038/S41586-022-04590-8 2022-04-27
8TRC GRM3 mGlu3 Metabotropic glutamate C (Glutamate) Human N/A 0 1 0 0 8TRC 3.3 10.1101/2023.08.13.552748 2024-07-31
7XK8 NMUR2 NMU2 Neuromedin U A (Rhodopsin) Human N/A 0 1 0 0 7XK8 3.3 10.1038/S41467-022-34814-4 2023-02-22
8W8R GP101 GPR101 A orphans A (Rhodopsin) Human N/A 0 0 0 0 8W8R 3.3 10.1038/S41589-023-01456-6 2024-01-03
4GRV NTR1 NTS1 Neurotensin A (Rhodopsin) Rat in meso/LCP 6 3 0 5 4GRV 2.8 10.1038/NATURE11558 2012-10-17
7Y35 PTH1R PTH1 Parathyroid hormone B1 (Secretin) Human N/A 0 1 0 0 7Y35 2.9 2023-07-05
8ZFJ E7FEL0 GPR4 A orphans A (Rhodopsin) Zebrafish N/A 0 0 0 0 8ZFJ 3.1 2024-08-07
6C1R C5AR1 C5a1 Complement peptide A (Rhodopsin) Human in meso/LCP 0 2 0 4 6C1R 2.2 10.1038/S41594-018-0067-Z 2018-05-30
8GNE AA2AR A2A Adenosine A (Rhodopsin) Human N/A 0 3 0 0 8GNE 2.3 10.1124/MOLPHARM.122.000633 2023-03-22
5XF1 GLR glucagon Glucagon B1 (Secretin) Human in meso/LCP 0 3 0 5 5XF1 3.2 2017-05-24
2Z73 OPSD Rhodopsin Opsins A (Rhodopsin) Japanese flying squid vapour diffusion 0 0 0 0 2Z73 2.5 10.1038/NATURE06925 2008-05-13
7EPF GRM2 mGlu2 Metabotropic glutamate C (Glutamate) Human N/A 0 2 0 0 7EPF 2.7 10.1038/S41586-021-03641-W 2021-06-23
5TGZ CNR1 CB1 Cannabinoid A (Rhodopsin) Human in meso/LCP 4 3 0 5 5TGZ 2.8 10.1016/J.CELL.2016.10.004 2016-11-02
2YCW ADRB1 β1 Adrenoceptors A (Rhodopsin) Wild turkey vapour diffusion 8 4 0 1 2YCW 3.0 10.1073/PNAS.1100185108 2011-06-01
5DHH OPRX NOP Opioid A (Rhodopsin) Human in meso/LCP 0 2 0 5 5DHH 3.0 10.1016/J.STR.2015.07.024 2015-10-21
8GAG CNR1 CB1 Cannabinoid A (Rhodopsin) Human N/A 0 0 0 0 8GAG 3.3 2024-02-28
8W8S GP101 GPR101 A orphans A (Rhodopsin) Human N/A 0 0 0 0 8W8S 3.3 10.1038/S41589-023-01456-6 2024-01-03
7XJJ GALR1 GAL1 Galanin A (Rhodopsin) Human N/A 0 1 0 0 7XJJ 3.3 2023-05-03
8XWQ EDNRB ETB Endothelin A (Rhodopsin) Human N/A 0 2 0 0 8XWQ 4.6 10.1038/S42003-024-06905-Z 2024-10-02
7JNI AGTR2 AT2 Angiotensin A (Rhodopsin) Human N/A 0 2 0 0 7JNI 3.0 10.1073/PNAS.2116289119 2022-02-09
7VUY MRGX2 MRGPRX2 A orphans A (Rhodopsin) Human N/A 0 0 0 0 7VUY 2.8 10.1038/S41586-021-04077-Y 2021-12-01
7CMV DRD3 D3 Dopamine A (Rhodopsin) Human N/A 0 0 0 0 7CMV 2.7 10.1016/J.MOLCEL.2021.01.003 2021-03-10
8KFY CCR8 CCR8 Chemokine A (Rhodopsin) Human N/A 0 0 0 0 8KFY 3.1 10.1126/SCIADV.ADJ7500 2024-02-07
4L6R GLR glucagon Glucagon B1 (Secretin) Human in meso/LCP 0 2 0 5 4L6R 3.3 10.1038/nature12393 2013-07-24
4PXZ P2Y12 P2Y12 P2Y A (Rhodopsin) Human in meso/LCP 1 1 0 5 4PXZ 2.5 10.1038/NATURE13288 2014-04-30
8FYT 5HT1A 5-HT1A 5-Hydroxytryptamine A (Rhodopsin) Human N/A 0 1 0 0 8FYT 2.6 10.1038/S41586-024-07403-2 2024-05-15
3QAK AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 0 3 0 5 3QAK 2.7 10.1126/SCIENCE.1202793 2011-03-09
6ZG9 ACM1 M1 Acetylcholine (muscarinic) A (Rhodopsin) Human N/A 0 3 0 0 6ZG9 2.5 10.1016/J.CELL.2021.11.001 2021-10-06
7ZBE OPSD Rhodopsin Opsins A (Rhodopsin) Bovine N/A 0 0 0 0 7ZBE 1.8 10.1038/S41586-023-05863-6 2023-03-29
7P02 NK1R NK1 Tachykinin A (Rhodopsin) Human N/A 0 1 0 0 7P02 2.9 10.1126/SCIADV.ABK2872 2021-12-15
6TQ4 OX1R OX1 Orexin A (Rhodopsin) Human N/A 0 2 0 2 6TQ4 2.3 10.1021/acs.jmedchem.9b01787 2020-01-01
7XNA SSR2 SST2 Somatostatin A (Rhodopsin) Human N/A 0 3 0 0 7XNA 2.7 10.1038/S41422-022-00679-X 2022-08-03
7V68 ACM4 M4 Acetylcholine (muscarinic) A (Rhodopsin) Human N/A 0 1 0 0 7V68 3.4 10.1038/S41467-022-30595-Y 2022-05-11
4UG2 AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 5 1 0 3 4UG2 2.6 10.1124/mol.114.097360 2015-04-08
8WWN MCHR1 MCH1 Melanin-concentrating hormone A (Rhodopsin) Human N/A 0 1 0 0 8WWN 2.7 10.1038/S41421-024-00754-0 2024-11-13
4EJ4 OPRD δ Opioid A (Rhodopsin) Mouse in meso/LCP 0 3 0 4 4EJ4 3.4 10.1038/NATURE11111 2012-05-16
8J24 FFAR2 FFA2 Free fatty acid A (Rhodopsin) Human N/A 0 1 0 0 8J24 2.6 10.1038/S41422-023-00914-Z 2024-01-24
7EZM CCKAR CCK1 Cholecystokinin A (Rhodopsin) Human N/A 0 0 0 0 7EZM 2.9 10.1038/S41589-021-00841-3 2021-08-25
6AQF AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 0 3 0 3 6AQF 2.5 10.1016/J.CELL.2017.12.004 2018-01-10
8IRR DRD1 D1 Dopamine A (Rhodopsin) Human N/A 0 0 0 0 8IRR 3.2 10.1038/S41422-023-00808-0 2023-06-21
3PDS ADRB2 β2 Adrenoceptors A (Rhodopsin) Human in meso/LCP 3 3 0 3 3PDS 3.5 10.1038/NATURE09665 2011-01-12
7YJ4 RL3R2 RXFP4 Relaxin family peptide A (Rhodopsin) Human N/A 0 0 0 0 7YJ4 3.2 10.1038/S41467-023-36182-Z 2023-03-01
8RQL T2R14 TAS2R14 Taste 2 T2 (Taste 2) Human N/A 0 0 0 0 8RQL 3.0 10.1038/S41467-024-54157-6 2024-11-27
7TYI CALCR CT Calcitonin B1 (Secretin) Human N/A 0 1 0 0 7TYI 3.3 10.1126/SCIENCE.ABM9609 2022-03-30
4AMI ADRB1 β1 Adrenoceptors A (Rhodopsin) Wild turkey vapour diffusion 8 3 0 1 4AMI 3.2 2012-05-23
6DDE OPRM μ Opioid A (Rhodopsin) Mouse Cryo-EM 0 2 0 4 6DDE 3.5 10.1038/S41586-018-0219-7 2018-06-13
7XJH ADRB3 β3 Adrenoceptors A (Rhodopsin) Dog N/A 0 2 0 0 7XJH 3.3 10.1016/J.MOLCEL.2021.06.024 2022-05-04
7UL2 NTR1 NTS1 Neurotensin A (Rhodopsin) Human N/A 0 2 0 0 7UL2 2.4 10.1038/S41594-022-00859-8 2022-06-29
1GZM OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 0 0 0 0 1GZM 2.7 10.1016/J.JMB.2004.08.090 2003-11-20
8GDA PE2R4 EP4 Prostanoid A (Rhodopsin) Human N/A 0 0 0 0 8GDA 3.3 10.1073/PNAS.2216329120 2024-01-10
6FK7 OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 2 0 0 0 6FK7 2.6 2018-04-04
8IKL AGRE5 ADGRE5 ADGRE B2 (Adhesion) Human N/A 0 2 0 0 8IKL 2.3 10.1016/J.MOLCEL.2023.12.020 2024-01-24
7VVN PTH1R PTH1 Parathyroid hormone B1 (Secretin) Human N/A 0 2 0 0 7VVN 3.8 10.1016/J.MOLCEL.2022.07.003 2022-08-03
8UNM ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8UNM 3.4 10.1038/S41586-024-07153-1 2024-03-06
7UM5 5HT5A 5-HT5A 5-Hydroxytryptamine A (Rhodopsin) Human N/A 0 1 0 0 7UM5 2.7 10.1038/S41594-022-00796-6 2022-07-20
8IRS DRD2 D2 Dopamine A (Rhodopsin) Human N/A 0 0 0 0 8IRS 3.0 10.1038/S41422-023-00808-0 2023-06-07
6NBH PTH1R PTH1 Parathyroid hormone B1 (Secretin) Human N/A 0 2 0 1 6NBH 3.5 10.1126/SCIENCE.AAV7942 2019-04-17
4QIN SMO SMO Frizzled F (Frizzled) Human in meso/LCP 0 3 0 5 4QIN 2.6 10.1038/NCOMMS5355 2014-07-23
4IAQ 5HT1B 5-HT1B 5-Hydroxytryptamine A (Rhodopsin) Human in meso/LCP 1 2 0 5 4IAQ 2.8 10.1126/SCIENCE.1232807 2013-03-13
7C4S S1PR3 S1P3 Lysophospholipid (S1P) A (Rhodopsin) Human N/A 0 0 0 0 7C4S 3.2 10.1126/SCIADV.ABF5325 2021-06-09
8HK2 C3AR C3a Complement peptide A (Rhodopsin) Human N/A 0 1 0 0 8HK2 2.9 10.1038/S41589-023-01339-W 2023-05-10
7EW0 S1PR1 S1P1 Lysophospholipid (S1P) A (Rhodopsin) Human N/A 0 1 0 0 7EW0 3.4 10.1038/S41422-021-00566-X 2021-09-29
7LCI GLP1R GLP-1 Glucagon B1 (Secretin) Human N/A 0 1 0 0 7LCI 2.9 2021-01-20
7YFC HRH4 H4 Histamine A (Rhodopsin) Human N/A 0 0 0 0 7YFC 3.0 10.1038/S41467-023-42260-Z 2023-10-25
7EPA GRM2 mGlu2 Metabotropic glutamate C (Glutamate) Human N/A 0 2 0 0 7EPA 3.6 10.1038/S41586-021-03641-W 2021-06-23
3PQR OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 0 0 0 0 3PQR 2.9 10.1038/NATURE09789 2011-03-09
1F88 OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 0 0 0 0 1F88 2.8 10.1126/SCIENCE.289.5480.739 2000-08-04
6U1N ACM2 M2 Acetylcholine (muscarinic) A (Rhodopsin) Human N/A 0 1 0 3 6U1N 4.0 10.1038/S41586-020-1954-0 2020-02-26
7W7E ADA2A α2A Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 7W7E 3.4 10.1126/SCIENCE.ABN7065 2022-09-28
9ERX CNR1 CB1 Cannabinoid A (Rhodopsin) Human N/A 0 1 0 0 9ERX 2.9 2024-06-26
7WVY FPR2 FPR2/ALX Formylpeptide A (Rhodopsin) Human N/A 0 2 0 0 7WVY 3.0 10.1038/S41467-022-29361-X 2022-04-13
6N52 GRM5 mGlu5 Metabotropic glutamate C (Glutamate) Human N/A 0 2 0 2 6N52 4.0 10.1038/S41586-019-0881-4 2019-01-23
8SZI CASR CaS Calcium-sensing C (Glutamate) Human N/A 0 2 0 0 8SZI 3.5 10.1038/S41586-024-07055-2 2024-02-07
7F6I BKRB2 B2 Bradykinin A (Rhodopsin) Human N/A 0 0 0 0 7F6I 2.8 10.1038/S41467-022-28399-1 2022-01-05
3RZE HRH1 H1 Histamine A (Rhodopsin) Human in meso/LCP 0 2 0 4 3RZE 3.1 10.1038/NATURE10236 2011-06-15
8UNP ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8UNP 3.3 10.1038/S41586-024-07153-1 2024-03-06
7XK9 ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 1 3 0 0 7XK9 3.4 2023-04-26
7NA7 GHSR ghrelin Ghrelin A (Rhodopsin) Human N/A 0 0 0 0 7NA7 2.7 10.1038/S41467-021-26735-5 2021-12-15
7KH0 V2R V2 Vasopressin and oxytocin A (Rhodopsin) Human N/A 0 0 0 0 7KH0 2.8 10.1038/S41422-021-00483-Z 2021-05-26
5X33 Q9WTK1 BLT1 Leukotriene A (Rhodopsin) Guinea pig in meso/LCP 4 1 0 5 5X33 3.7 10.1038/NCHEMBIO.2547 2018-01-03
8XJO TA2R TP Prostanoid A (Rhodopsin) Human N/A 0 1 0 0 8XJO 3.1 10.1016/J.CELREP.2024.113893 2024-02-28
3UZA AA2AR A2A Adenosine A (Rhodopsin) Human vapour diffusion 8 1 0 2 3UZA 3.3 10.1021/jm201376w 2012-03-21
8YKW SUCR1 succinate Succinate A (Rhodopsin) Human N/A 0 0 0 0 8YKW 2.8 10.1038/S41422-024-00984-7 2024-05-29
8YNA HRH4 H4 Histamine A (Rhodopsin) Human N/A 0 1 0 0 8YNA 2.6 2024-10-09
8KFX CCR8 CCR8 Chemokine A (Rhodopsin) Human N/A 0 0 0 0 8KFX 3.0 10.1126/SCIADV.ADJ7500 2024-02-07
8IY9 HCAR2 HCA2 Hydroxycarboxylic acid A (Rhodopsin) Human N/A 0 1 0 0 8IY9 3.4 10.1038/S41467-024-46239-2 2024-03-06
8DPF 5HT2C 5-HT2C 5-Hydroxytryptamine A (Rhodopsin) Human N/A 0 0 0 0 8DPF 2.8 10.1016/J.CELREP.2022.111211 2022-08-24
8IWE TAAR9 TAAR9 A orphans A (Rhodopsin) Mouse N/A 0 0 0 0 8IWE 3.4 10.1038/S41586-023-06106-4 2023-05-31
3OE8 CXCR4 CXCR4 Chemokine A (Rhodopsin) Human in meso/LCP 1 2 0 7 3OE8 3.1 2010-10-27
6PGS OPSD Rhodopsin Opsins A (Rhodopsin) Bovine N/A 0 0 0 0 6PGS 2.9 2020-07-01
8E9W ACM3 M3 Acetylcholine (muscarinic) A (Rhodopsin) Human N/A 0 2 0 0 8E9W 2.7 10.1038/S41586-022-05489-0 2022-11-30
7EW3 S1PR3 S1P3 Lysophospholipid (S1P) A (Rhodopsin) Human N/A 0 0 0 0 7EW3 3.1 10.1038/S41422-021-00567-W 2021-09-29
8GEF ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8GEF 3.8 10.1038/S41586-024-07153-1 2024-03-06
6HLP NK1R NK1 Tachykinin A (Rhodopsin) Human N/A 0 2 0 1 6HLP 2.2 10.1038/S41467-018-07939-8 2019-01-16
7FIH LSHR LH Glycoprotein hormone A (Rhodopsin) Human N/A 0 1 0 0 7FIH 3.2 10.1038/S41586-021-03924-2 2021-09-29
5XSZ Q08BG4 LPA6 Lysophospholipid (LPA) A (Rhodopsin) Zebrafish in meso/LCP 0 2 0 6 5XSZ 3.2 10.1038/NATURE23448 2017-08-16
7VOE 5HT2A 5-HT2A 5-Hydroxytryptamine A (Rhodopsin) Human N/A 0 3 0 0 7VOE 2.9 10.1038/S41593-021-00971-W 2021-12-22
8EJC FFAR1 FFA1 Free fatty acid A (Rhodopsin) Human N/A 0 1 0 0 8EJC 3.0 10.1073/PNAS.2219569120 2023-05-24
4ZWJ OPSD Rhodopsin Opsins A (Rhodopsin) Human in meso/LCP 4 0 0 7 4ZWJ 3.3 10.1038/NATURE14656 2015-07-29
8XVH EDNRB ETB Endothelin A (Rhodopsin) Human N/A 0 2 0 0 8XVH 3.3 10.1038/S41421-024-00705-9 2024-08-28
8U4O CXCR4 CXCR4 Chemokine A (Rhodopsin) Human N/A 0 1 0 0 8U4O 3.3 10.1038/S41594-024-01397-1 2024-03-13
7SK5 ACKR3 ACKR3 Chemokine A (Rhodopsin) Human N/A 0 1 0 0 7SK5 4.0 10.1126/SCIADV.ABN8063 2022-07-27
7UL4 OPRM μ Opioid A (Rhodopsin) Mouse N/A 0 1 0 0 7UL4 2.8 10.1038/S41594-022-00859-8 2022-06-29
7VVL PTH1R PTH1 Parathyroid hormone B1 (Secretin) Human N/A 0 2 0 0 7VVL 2.8 10.1016/J.MOLCEL.2022.07.003 2022-08-03
8FY8 5HT1A 5-HT1A 5-Hydroxytryptamine A (Rhodopsin) Human N/A 0 1 0 0 8FY8 2.8 10.1038/S41586-024-07403-2 2024-05-15
5G53 AA2AR A2A Adenosine A (Rhodopsin) Human vapour diffusion 1 1 0 2 5G53 3.4 10.1038/NATURE18966 2016-08-03
6TP3 OX1R OX1 Orexin A (Rhodopsin) Human N/A 0 2 0 2 6TP3 3.0 10.1021/acs.jmedchem.9b01787 2020-01-01
6B73 OPRK κ Opioid A (Rhodopsin) Human in meso/LCP 1 2 0 6 6B73 3.1 10.1016/J.CELL.2017.12.011 2018-01-17
5ZBQ NPY1R Y1 Neuropeptide Y A (Rhodopsin) Human in meso/LCP 1 2 0 5 5ZBQ 2.7 10.1038/S41586-018-0046-X 2018-04-25
7WQ3 GALR1 GAL1 Galanin A (Rhodopsin) Human N/A 0 0 0 0 7WQ3 2.7 10.1038/S41467-022-29072-3 2022-04-20
8IA8 C3AR C3a Complement peptide A (Rhodopsin) Human N/A 0 0 0 0 8IA8 2.9 2023-05-24
8X7A PI2R IP Prostanoid A (Rhodopsin) Human N/A 0 0 0 0 8X7A 2.6 10.1126/SCIADV.ADK5184 2024-03-06
8U4N CXCR4 CXCR4 Chemokine A (Rhodopsin) Human N/A 0 1 0 0 8U4N 2.7 10.1038/S41594-024-01397-1 2024-03-13
7KI1 GLP1R GLP-1 Glucagon B1 (Secretin) Human N/A 0 1 0 0 7KI1 2.5 10.1016/J.CELREP.2021.109374 2021-08-04
3UZC AA2AR A2A Adenosine A (Rhodopsin) Human vapour diffusion 8 1 0 2 3UZC 3.3 10.1021/jm201376w 2012-03-21
7XTA 5HT4R 5-HT4 5-Hydroxytryptamine A (Rhodopsin) Human N/A 0 1 0 0 7XTA 3.2 10.1016/J.MOLCEL.2022.05.031 2022-07-27
7TRP ACM4 M4 Acetylcholine (muscarinic) A (Rhodopsin) Human N/A 0 1 0 0 7TRP 2.4 2023-05-17
8ZPT PRLHR PrRP Prolactin-releasing peptide A (Rhodopsin) Human N/A 0 0 0 0 8ZPT 3.0 10.1038/S41421-024-00724-6 2024-09-25
8JLN TAAR1 TA1 Trace amine A (Rhodopsin) Human N/A 0 0 0 0 8JLN 3.2 10.1038/S41586-023-06804-Z 2023-11-15
7F6G AGTR1 AT1 Angiotensin A (Rhodopsin) Human N/A 0 1 0 0 7F6G 2.9 2023-03-29
5X7D ADRB2 β2 Adrenoceptors A (Rhodopsin) Human in meso/LCP 3 2 0 2 5X7D 2.7 10.1038/NATURE23652 2017-08-16
6LFM CXCR2 CXCR2 Chemokine A (Rhodopsin) Human N/A 0 0 0 0 6LFM 3.5 10.1038/S41586-020-2492-5 2020-09-02
7TD1 LPAR1 LPA1 Lysophospholipid (LPA) A (Rhodopsin) Human N/A 0 2 0 0 7TD1 3.1 10.1038/S41467-022-28417-2 2022-02-09
7Y15 MRGRD MRGPRD A orphans A (Rhodopsin) Human N/A 0 1 0 0 7Y15 2.9 10.1038/S42003-022-03668-3 2022-07-20
8IOC MC3R MC3 Melanocortin A (Rhodopsin) Human N/A 0 1 0 0 8IOC 2.9 10.1107/S0907444909042073 2023-09-20
4N6H OPRD δ Opioid A (Rhodopsin) Human in meso/LCP 1 2 0 5 4N6H 1.8 10.1038/NATURE12944 2013-12-25
8U4Q CXCR4 CXCR4 Chemokine A (Rhodopsin) Human N/A 0 1 0 0 8U4Q 3.4 10.1038/S41594-024-01397-1 2024-03-13
8GE7 ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8GE7 3.4 10.1038/S41586-024-07153-1 2024-03-06
7YON NPY2R Y2 Neuropeptide Y A (Rhodopsin) Human N/A 0 1 0 0 7YON 3.0 10.1016/J.STR.2022.11.010 2023-03-22
8DZS OPRK κ Opioid A (Rhodopsin) Human N/A 1 2 0 0 8DZS 2.7 10.1038/S41586-023-06030-7 2023-05-03
6FUF OPSD Rhodopsin Opsins A (Rhodopsin) Bovine N/A 0 2 0 0 6FUF 3.1 10.1126/SCIADV.AAT7052 2018-10-03
4O9R SMO SMO Frizzled F (Frizzled) Human in meso/LCP 0 3 0 1 4O9R 3.2 10.1038/NCOMMS4309 2014-03-05
2Y03 ADRB1 β1 Adrenoceptors A (Rhodopsin) Wild turkey vapour diffusion 8 3 0 1 2Y03 2.9 10.1038/NATURE09746 2011-01-12
8PWN AA2AR A2A Adenosine A (Rhodopsin) Human N/A 0 3 0 0 8PWN 2.4 10.1038/S42004-023-01014-0 2023-10-25
8UNN ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8UNN 3.4 10.1038/S41586-024-07153-1 2024-03-06
8XXV PD2R2 DP2 Prostanoid A (Rhodopsin) Human N/A 0 1 0 0 8XXV 2.3 2024-12-04
7XP4 T2R46 TAS2R46 Taste 2 T2 (Taste 2) Human N/A 0 1 0 0 7XP4 3.0 10.1126/SCIENCE.ABO1633 2022-10-12
5F8U ADRB1 β1 Adrenoceptors A (Rhodopsin) Wild turkey vapour diffusion 8 4 0 2 5F8U 3.4 10.1038/NSMB.3130 2015-12-23
8UYQ OR4D5 OR4D5 Odorant family 4 O2 (tetrapod specific odorant) Human N/A 0 1 0 0 8UYQ 3.5 10.1038/S41586-024-08126-0 2024-10-30
7F55 MC4R MC4 Melanocortin A (Rhodopsin) Human N/A 0 0 0 0 7F55 3.1 2021-11-03
8X0B GRM5 mGlu5 Metabotropic glutamate C (Glutamate) Human N/A 2 2 0 0 8X0B 3.1 10.1038/S41467-024-55439-9 2024-11-06
8K4P Q76SF8 ORF74 Unclassified A (Rhodopsin) HHV-8 N/A 0 2 0 0 8K4P 2.8 2024-07-24
8WC9 TAAR1 TA1 Trace amine A (Rhodopsin) Mouse N/A 0 0 0 0 8WC9 3.2 10.1016/J.CELL.2023.10.014 2023-12-27
7EWL GP158 GPR158 C Orphans C (Glutamate) Human N/A 0 2 0 0 7EWL 3.5 10.1038/S41467-021-27147-1 2021-12-01
8FLS PTH1R PTH1 Parathyroid hormone B1 (Secretin) Human N/A 0 1 0 0 8FLS 3.1 10.1016/J.STR.2023.04.002 2023-04-26
7T9I TSHR TSH Glycoprotein hormone A (Rhodopsin) Human N/A 0 1 0 0 7T9I 2.9 10.1038/S41586-022-05159-1 2022-08-03
8KH5 GP174 GPR174 A orphans A (Rhodopsin) Human N/A 0 2 0 0 8KH5 2.8 10.1038/S41467-023-41654-3 2023-10-18
7M8W PD2R2 DP2 Prostanoid A (Rhodopsin) Human N/A 0 2 0 0 7M8W 2.6 10.1073/PNAS.2102813118 2021-08-25
3VGA AA2AR A2A Adenosine A (Rhodopsin) Human vapour diffusion 1 1 0 3 3VGA 3.1 10.1038/NATURE10750 2012-02-01
7XA3 CCR2 CCR2 Chemokine A (Rhodopsin) Human N/A 0 1 0 0 7XA3 2.9 10.1038/S41421-022-00403-4 2022-08-24
6PB0 CRFR1 CRF1 Corticotropin-releasing factor B1 (Secretin) Human N/A 0 2 0 0 6PB0 3.0 10.1016/J.MOLCEL.2020.01.013 2020-02-12
6TP4 OX1R OX1 Orexin A (Rhodopsin) Human N/A 0 3 0 2 6TP4 3.0 10.1021/acs.jmedchem.9b01787 2020-01-01
8ZJE KISSR kisspeptin Kisspeptin A (Rhodopsin) Human N/A 0 0 0 0 8ZJE 3.1 2024-07-03
8TZQ DRD2 D2 Dopamine A (Rhodopsin) Human N/A 0 0 0 0 8TZQ 3.2 10.1038/S41467-024-50964-Z 2024-08-21
8FMZ NTR1 NTS1 Neurotensin A (Rhodopsin) Rat N/A 1 2 0 0 8FMZ 2.6 10.1021/ACS.BIOCHEM.3C00029 2023-03-29
6V9S OX1R OX1 Orexin A (Rhodopsin) Human N/A 1 2 0 0 6V9S 3.5 10.1073/PNAS.2002704117 2020-07-15
6FKA OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 2 0 0 0 6FKA 2.7 10.1073/PNAS.1718084115 2018-04-04
8INR MC5R MC5 Melanocortin A (Rhodopsin) Human N/A 0 1 0 0 8INR 2.7 10.1107/S0907444909042073 2023-09-20
8GGC ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8GGC 3.4 10.1038/S41586-024-07153-1 2024-03-06
7TD0 LPAR1 LPA1 Lysophospholipid (LPA) A (Rhodopsin) Human N/A 0 2 0 0 7TD0 2.8 10.1038/S41467-022-28417-2 2022-02-09
8ZQE GPR15 GPR15 A orphans A (Rhodopsin) Human N/A 0 1 0 0 8ZQE 2.9 10.1038/S41421-024-00698-5 2024-07-10
7YIT OPRK κ Opioid A (Rhodopsin) Human N/A 1 2 0 0 7YIT 3.3 10.1038/S41467-023-37041-7 2023-04-12
7LD3 AA1R A1 Adenosine A (Rhodopsin) Human N/A 0 1 0 0 7LD3 3.2 10.1038/S41586-021-03897-2 2021-09-08
6LI0 GPR52 GPR52 A orphans A (Rhodopsin) Human N/A 0 3 0 4 6LI0 2.2 10.1038/S41586-020-2019-0 2020-02-26
8P13 OPSD Rhodopsin Opsins A (Rhodopsin) Bovine N/A 0 0 0 0 8P13 5.2 2024-11-20
5UVI AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 0 3 0 4 5UVI 3.2 10.1107/S205225251700570X 2017-05-24
7S8P MRGX4 MRGPRX4 A orphans A (Rhodopsin) Human N/A 0 1 0 0 7S8P 2.6 10.1038/S41586-021-04126-6 2021-11-17
8GFX ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8GFX 3.0 10.1038/S41586-024-07153-1 2024-03-06
8HQC C5AR1 C5a1 Complement peptide A (Rhodopsin) Mouse N/A 0 1 0 0 8HQC 3.9 HTTPS://DOI.ORG/10.1016/J.CELL.2023.09.020 2023-10-18
6KK7 GLP1R GLP-1 Glucagon B1 (Secretin) Human N/A 0 4 0 3 6KK7 3.1 10.1107/S2052252519013496 2019-11-13
8TQB GRM3 mGlu3 Metabotropic glutamate C (Glutamate) Human N/A 0 1 0 0 8TQB 3.3 10.1101/2023.08.13.552748 2024-07-31
3OE6 CXCR4 CXCR4 Chemokine A (Rhodopsin) Human in meso/LCP 1 2 0 7 3OE6 3.2 10.1126/SCIENCE.1194396 2010-10-27
7VQX VIPR2 VPAC2 VIP and PACAP B1 (Secretin) Human N/A 0 1 0 0 7VQX 2.7 10.1038/S41467-022-30041-Z 2022-05-18
7TZF CALCR CT Calcitonin B1 (Secretin) Human N/A 0 1 0 0 7TZF 2.4 10.1126/SCIENCE.ABM9609 2022-03-23
4IB4 5HT2B 5-HT2B 5-Hydroxytryptamine A (Rhodopsin) Human in meso/LCP 1 3 0 5 4IB4 2.7 10.1126/science.1232808 2013-03-13
8IW7 TAAR9 TAAR9 A orphans A (Rhodopsin) Mouse N/A 0 0 0 0 8IW7 3.0 10.1038/S41586-023-06106-4 2023-05-31
8XQL T2R14 TAS2R14 Taste 2 T2 (Taste 2) Human N/A 0 1 0 0 8XQL 3.0 10.1038/S41586-024-07569-9 2024-07-10
5CXV ACM1 M1 Acetylcholine (muscarinic) A (Rhodopsin) Human in meso/LCP 3 2 0 4 5CXV 2.7 10.1038/NATURE17188 2016-03-09
2R4S ADRB2 β2 Adrenoceptors A (Rhodopsin) Human vapour diffusion 1 2 0 3 2R4S 3.4 10.1038/NATURE06325 2007-11-06
8UXY OR1F1 OR1F1 Odorant family 1 O2 (tetrapod specific odorant) Human N/A 0 1 0 0 8UXY 3.3 10.1038/S41586-024-08126-0 2024-10-30
8K2W CXCR3 CXCR3 Chemokine A (Rhodopsin) Human N/A 0 2 0 0 8K2W 3.0 10.1038/S41421-023-00617-0 2023-11-29
7WUI AGRG2 ADGRG2 ADGRG B2 (Adhesion) Mouse N/A 0 2 0 0 7WUI 3.1 10.1038/S41586-022-04590-8 2022-04-27
8I97 C3AR C3a Complement peptide A (Rhodopsin) Human N/A 0 1 0 0 8I97 3.2 10.1016/J.CELL.2023.09.020 2023-10-18
7XAT SSR2 SST2 Somatostatin A (Rhodopsin) Human N/A 0 1 0 0 7XAT 2.9 10.1038/S41421-022-00405-2 2022-08-31
7F8V GASR CCK2 Cholecystokinin A (Rhodopsin) Human N/A 0 2 0 0 7F8V 3.3 10.1038/S41589-021-00866-8 2021-10-13
5NM4 AA2AR A2A Adenosine A (Rhodopsin) Human in meso/LCP 9 3 0 4 5NM4 1.7 10.1038/S41467-017-00630-4 2017-09-27
6NIY CALCR CT Calcitonin B1 (Secretin) Human N/A 0 0 0 1 6NIY 3.3 10.1021/ACSPTSCI.8B00056 2019-01-23
7Y14 MRGRD MRGPRD A orphans A (Rhodopsin) Human N/A 0 1 0 0 7Y14 3.2 10.1038/S42003-022-03668-3 2022-07-20
7FIJ LSHR LH Glycoprotein hormone A (Rhodopsin) Human N/A 0 1 0 0 7FIJ 3.8 10.1038/S41586-021-03924-2 2021-09-29
8WRZ CNR1 CB1 Cannabinoid A (Rhodopsin) Human N/A 0 2 0 0 8WRZ 3.6 10.1093/PROCEL/PWAD055 2024-02-28
8GGF ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8GGF 3.6 10.1038/S41586-024-07153-1 2024-03-06
7YU7 LPAR1 LPA1 Lysophospholipid (LPA) A (Rhodopsin) Human N/A 0 1 0 0 7YU7 3.8 10.1038/S41467-022-33121-2 2022-10-05
7RAN 5HT2A 5-HT2A 5-Hydroxytryptamine A (Rhodopsin) Human N/A 0 2 0 0 7RAN 3.5 10.1038/S41586-022-05258-Z 2022-07-06
6LPJ AA2AR A2A Adenosine A (Rhodopsin) Human N/A 0 3 0 0 6LPJ 1.8 10.1038/S41598-020-76277-X 2020-11-25
7EPD GRM2 mGlu2 Metabotropic glutamate C (Glutamate) Human N/A 0 2 0 0 7EPD 3.9 10.1038/S41586-021-03641-W 2021-06-23
7C7S GABR2 GABAB2 GABAB C (Glutamate) Human N/A 0 2 0 0 7C7S 2.9 10.1038/S41422-020-0350-5 2020-07-01
7C61 5HT1B 5-HT1B 5-Hydroxytryptamine A (Rhodopsin) Human N/A 1 2 0 0 7C61 3.0 10.1038/S41598-020-68355-X 2020-07-29
4WW3 OPSD Rhodopsin Opsins A (Rhodopsin) Japanese flying squid vapour diffusion 0 2 0 1 4WW3 2.8 10.1371/JOURNAL.PONE.0126970 2015-06-17
6LI2 GPR52 GPR52 A orphans A (Rhodopsin) Human N/A 0 3 0 5 6LI2 2.8 10.1038/S41586-020-2019-0 2020-02-26
8FN0 NTR1 NTS1 Neurotensin A (Rhodopsin) Rat N/A 1 1 0 0 8FN0 2.9 10.1021/ACS.BIOCHEM.3C00029 2023-03-29
4IAR 5HT1B 5-HT1B 5-Hydroxytryptamine A (Rhodopsin) Human in meso/LCP 1 2 0 5 4IAR 2.7 10.1126/SCIENCE.1232807 2013-03-13
3PXO OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 0 0 0 0 3PXO 3.0 10.1038/NATURE09789 2011-03-09
7V6A ACM4 M4 Acetylcholine (muscarinic) A (Rhodopsin) Human N/A 0 1 0 0 7V6A 3.6 10.1038/S41467-022-30595-Y 2022-05-11
8HJ5 MRGX1 MRGPRX1 A orphans A (Rhodopsin) Human N/A 0 0 0 0 8HJ5 3.0 2023-05-31
7F4D MSHR MC1 Melanocortin A (Rhodopsin) Human N/A 0 1 0 0 7F4D 3.0 10.1038/S41422-021-00557-Y 2021-09-08
4JKV SMO SMO Frizzled F (Frizzled) Human in meso/LCP 0 2 0 5 4JKV 2.5 10.1038/NATURE12167 2013-04-24
5TE3 OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 0 0 0 0 5TE3 2.7 10.1073/PNAS.1617446114 2017-03-15
7Y12 MRGRD MRGPRD A orphans A (Rhodopsin) Human N/A 0 1 0 0 7Y12 3.1 10.1038/S42003-022-03668-3 2022-07-20
8GGO ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8GGO 3.2 10.1038/S41586-024-07153-1 2024-03-06
8JWZ AA2AR A2A Adenosine A (Rhodopsin) Human N/A 0 3 0 0 8JWZ 2.4 2023-08-16
7P00 NK1R NK1 Tachykinin A (Rhodopsin) Human N/A 0 1 0 0 7P00 2.7 10.1126/SCIADV.ABK2872 2021-12-15
6Z4S NTR1 NTS1 Neurotensin A (Rhodopsin) Rat N/A 1 1 0 0 6Z4S 2.7 10.1126/sciadv.abe5504 2021-02-10
3UON ACM2 M2 Acetylcholine (muscarinic) A (Rhodopsin) Human in meso/LCP 4 1 0 1 3UON 3.0 10.1038/NATURE10753 2012-02-01
3OAX OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 0 0 0 0 3OAX 2.6 10.1016/J.BPJ.2010.08.003 2011-01-19
8JXW HRH4 H4 Histamine A (Rhodopsin) Human N/A 0 0 0 0 8JXW 3.0 10.1038/S41467-024-46840-5 2024-03-20
8ZSJ TAAR1 TA1 Trace amine A (Rhodopsin) Human N/A 0 1 0 0 8ZSJ 2.8 10.1016/J.CELREP.2024.114505 2024-07-24
8E9Y ACM3 M3 Acetylcholine (muscarinic) A (Rhodopsin) Human N/A 0 2 0 0 8E9Y 2.8 10.1038/S41586-022-05489-0 2022-11-30
8XJK PF2R FP Prostanoid A (Rhodopsin) Human N/A 0 1 0 0 8XJK 2.6 2024-02-28
8XQS T2R14 TAS2R14 Taste 2 T2 (Taste 2) Human N/A 0 1 0 0 8XQS 3.3 10.1038/S41586-024-07569-9 2024-07-10
7DW9 V2R V2 Vasopressin and oxytocin A (Rhodopsin) Human N/A 0 0 0 0 7DW9 2.6 10.1038/S41422-021-00480-2 2021-07-21
7O7F CCR5 CCR5 Chemokine A (Rhodopsin) Human N/A 0 0 0 0 7O7F 3.2 10.1126/SCIADV.ABG8685 2021-06-30
3SN6 ADRB2 β2 Adrenoceptors A (Rhodopsin) Human sponge mesophase 3 2 0 4 3SN6 3.2 10.1038/NATURE10361 2011-07-20
8UNX ADRB2 β2 Adrenoceptors A (Rhodopsin) Human N/A 0 0 0 0 8UNX 3.6 10.1038/S41586-024-07153-1 2024-03-06
7FIN GIPR GIP Glucagon B1 (Secretin) Human N/A 0 2 0 0 7FIN 3.1 10.1038/S41467-022-28683-0 2022-02-23
6OIJ ACM1 M1 Acetylcholine (muscarinic) A (Rhodopsin) Human N/A 3 2 0 2 6OIJ 3.3 10.1126/SCIENCE.AAW5188 2019-05-08
7V69 ACM4 M4 Acetylcholine (muscarinic) A (Rhodopsin) Human N/A 0 1 0 0 7V69 3.4 2022-05-11
8WCB TAAR1 TA1 Trace amine A (Rhodopsin) Mouse N/A 0 0 0 0 8WCB 3.1 10.1016/J.CELL.2023.10.014 2023-12-27
6DRZ 5HT2B 5-HT2B 5-Hydroxytryptamine A (Rhodopsin) Human N/A 1 3 0 2 6DRZ 3.1 10.1038/s41594-018-0116-7 2018-08-29
6BQG 5HT2C 5-HT2C 5-Hydroxytryptamine A (Rhodopsin) Human in meso/LCP 1 3 0 5 6BQG 3.0 10.1016/j.cell.2018.01.001 2018-02-14
8JHN HCAR2 HCA2 Hydroxycarboxylic acid A (Rhodopsin) Human N/A 0 1 0 0 8JHN 3.8 10.1038/S41467-024-46239-2 2024-03-06
8ID8 FFAR4 FFA4 Free fatty acid A (Rhodopsin) Human N/A 0 0 0 0 8ID8 3.0 10.1126/SCIENCE.ADD6220 2023-03-15
8J23 FFAR2 FFA2 Free fatty acid A (Rhodopsin) Human N/A 0 1 0 0 8J23 3.2 2024-04-17
8XQO T2R14 TAS2R14 Taste 2 T2 (Taste 2) Human N/A 0 1 0 0 8XQO 2.8 10.1038/S41586-024-07569-9 2024-07-10
4OR2 GRM1 mGlu1 Metabotropic glutamate C (Glutamate) Human in meso/LCP 0 2 0 5 4OR2 2.8 10.1126/science.1249489 2014-03-19
6LFL CXCR2 CXCR2 Chemokine A (Rhodopsin) Human N/A 0 3 0 0 6LFL 3.2 10.1038/S41586-020-2492-5 2020-09-02
8JPN SUCR1 succinate Succinate A (Rhodopsin) Human N/A 0 0 0 0 8JPN 2.9 2024-05-22
6ME5 MTR1A MT1 Melatonin A (Rhodopsin) Human N/A 0 3 0 2 6ME5 3.2 10.1038/S41586-019-1141-3 2019-04-24
4NTJ P2Y12 P2Y12 P2Y A (Rhodopsin) Human in meso/LCP 1 1 0 5 4NTJ 2.6 10.1038/NATURE13083 2014-03-26
7XP6 T2R46 TAS2R46 Taste 2 T2 (Taste 2) Human N/A 0 1 0 0 7XP6 3.0 10.1126/SCIENCE.ABO1633 2022-10-12
6BQH 5HT2C 5-HT2C 5-Hydroxytryptamine A (Rhodopsin) Human in meso/LCP 1 3 0 5 6BQH 2.7 10.1016/j.cell.2018.01.001 2018-02-14
2YCZ ADRB1 β1 Adrenoceptors A (Rhodopsin) Wild turkey vapour diffusion 8 4 0 1 2YCZ 3.7 10.1073/PNAS.1100185108 2011-06-01
2X72 OPSD Rhodopsin Opsins A (Rhodopsin) Bovine vapour diffusion 3 0 0 0 2X72 3.0 10.1038/NATURE09795 2011-03-16
7WIG SSR2 SST2 Somatostatin A (Rhodopsin) Human N/A 0 0 0 0 7WIG 2.7 10.1038/S41422-022-00669-Z 2022-06-01
6YVR NTR1 NTS1 Neurotensin A (Rhodopsin) Rat N/A 1 1 0 0 6YVR 2.5 10.1126/sciadv.abe5504 2021-02-10
PDB UniProt Receptor
2R4R ADRB2 β2
8CU7 AA2AR A2A
6PT2 OPRD δ
7EW2 S1PR3 S1P3
7FIG LSHR LH
7EXD 5HT1F 5-HT1F
7EVM GLP1R GLP-1
7FII LSHR LH
6DO1 AGTR1 AT1
7S8N MRGX2 MRGPRX2
7S8M MRGX2 MRGPRX2
6RZ4 CLTR1 CysLT1
3PWH AA2AR A2A
5WB2 Q80KM9 US28
7JOZ DRD1 D1
7F54 MC4R MC4
7CX4 PE2R2 EP2
7F1R CCR5 CCR5
5ZK3 ACM2 M2
8QOT OPRM μ
8JJ8 ADRB2 β2
7EW4 S1PR3 S1P3
6OBA ADRB2 β2
7RTB GLP1R GLP-1
7AUE MC4R MC4
6H7M ADRB1 β1
7CX2 PE2R2 EP2
2Y00 ADRB1 β1
7MTS GRM2 mGlu2
6CM4 DRD2 D2
2ZIY OPSD Rhodopsin
7RMG NK1R NK1
7JHJ Q3KSP2 BILF1
7K15 LT4R1 BLT1
7EW1 S1PR5 S1P5
7F1Q CCR5 CCR5
7EZH CCKAR CCK1
6A93 5HT2A 5-HT2A
6W2X GABR2 GABAB2
6LW5 FPR2 FPR2/ALX
7SK6 ACKR3 ACKR3
7F9Y GHSR ghrelin
7F9Z GHSR ghrelin
7DUQ GLP1R GLP-1
7UM4 5HT5A 5-HT5A
7F8U CCKAR CCK1
3REY AA2AR A2A
4LDL ADRB2 β2
7BB7 V2R V2
7T32 AA2AR A2A
7FD8 GRM5 mGlu5
7PIV MC4R MC4
7RMI NK1R NK1
7E2Z 5HT1A 5-HT1A
7E32 5HT1D 5-HT1D
7DUR GLP1R GLP-1
7E9H GRM4 mGlu4
7KI0 GLP1R GLP-1
7EVW FZD7 FZD7
6WJC ACM1 M1
7S8L MRGX2 MRGPRX2
4U16 ACM3 M3
7PP1 P2Y12 P2Y12
7LD4 AA1R A1
7SK4 ACKR3 ACKR3
8CXO SMO SMO
5WB1 Q80KM9 US28
3P0G ADRB2 β2
7SK7 ACKR3 ACKR3
7EB2 GABR2 GABAB2
6JZH AA2AR A2A
7E9G GRM2 mGlu2
7EZK CCKAR CCK1
7DH5 ADRB3 β3
7F2O BKRB2 B2
4ZJC OX1R OX1
7EIB BKRB1 B1
7XW7 TSHR TSH
5ZK8 ACM2 M2
7BB6 V2R V2
4LDO ADRB2 β2
7FD9 GRM5 mGlu5
7DTY GIPR GIP
7WC7 5HT2A 5-HT2A
7F53 MC4R MC4
8DU3 AA2AR A2A
7MBX CCKAR CCK1
5WF6 AA2AR A2A
8IC0 CXCR1 CXCR1
6J20 NK1R NK1
7XRR OX2R OX2
7VBI GLP1R GLP-1
7LLY GLP1R GLP-1
7T6V FPR2 FPR2/ALX
7F61 HRH3 H3
7SCG OPRM μ
3RFM AA2AR A2A
7VUZ MRGX2 MRGPRX2
8K5C HCAR2 HCA2
7EW7 S1PR1 S1P1
7RKF US28 US28
6UUN CALRL calcitonin-like
7F4I MSHR MC1
7SK9 ACKR3 ACKR3
6KP6 ACM4 M4
7T6S FPR2 FPR2/ALX
7EJ8 ADA2A α2A
7VLA CCR1 CCR1
7VUJ GP139 GPR139
7TYN CALCR CT
4BEZ OPSD Rhodopsin
4XNW P2RY1 P2Y1
7W2Z GHSR ghrelin
7F4H MSHR MC1
5U09 CNR1 CB1
6S0L AA2AR A2A
7LLL GLP1R GLP-1
7WVU FPR1 FPR1
6J21 NK1R NK1
7EJA ADA2A α2A
7T6U FPR2 FPR2/ALX
7VL8 CCR1 CCR1
7SBF OPRM μ
7WQ4 GALR2 GAL2
7F4F MSHR MC1
7WVX FPR2 FPR2/ALX
6ME4 MTR1A MT1
7DD5 CASR CaS
7VGX NPY1R Y1
7TD4 S1PR1 S1P1
7EVZ S1PR1 S1P1
7F83 GHSR ghrelin
6KK1 GLP1R GLP-1
7VV5 MRGX2 MRGPRX2
7VDH MRGX2 MRGPRX2
5ZKB ACM2 M2
6IGK EDNRB ETB
7NA8 GHSR ghrelin
7T6T FPR1 FPR1
8JJL ADRB2 β2
7VH0 MTR1B MT2
7FEE CNR1 CB1
7VUI GP139 GPR139
7TYF CALCR CT
7EJ0 ADA2A α2A
6S0Q AA2AR A2A
7RKM US28 US28
7TD3 S1PR1 S1P1
7T11 SSR2 SST2
9D3E CCR6 CCR6
7EVY S1PR1 S1P1
7SRQ 5HT2B 5-HT2B
7WVW FPR2 FPR2/ALX
7V9M GHRHR GHRH
7FIY GIPR GIP
7VGZ MTR1A MT1
6RZ5 CLTR1 CysLT1
7FIM GLP1R GLP-1
7VDL MRGX2 MRGPRX2
7VUH GP139 GPR139
6RZ6 CLTR2 CysLT2
7WVV FPR2 FPR2/ALX
7TYW CALCR CT
7VGY MTR1A MT1
7VV3 MRGX2 MRGPRX2
7T10 SSR2 SST2
2RH1 ADRB2 β2
7EO2 S1PR1 S1P1
6ME3 MTR1A MT1
7S3I GLP1R GLP-1
7TYH CALCR CT
7VAB GIPR GIP
7S8O MRGX2 MRGPRX2
7WF7 S1PR1 S1P1
7VL9 CCR1 CCR1
7TYO CALCR CT
6UP7 NTR1 NTS1
6RZ8 CLTR2 CysLT2
7V35 GLR glucagon
7SF8 AGRG1 ADGRG1
7W0P APJ apelin
5XJM AGTR2 AT2
9IZH LPAR1 LPA1
4MQS ACM2 M2
8X63 HRH1 H1
5ZKC ACM2 M2
7XOW GASR CCK2
7WIC SSR2 SST2
7SF7 AGRL3 ADGRL3
8K5B HCAR2 HCA2
7X9B NPY2R Y2
7P2L GRM5 mGlu5
7UM6 5HT5A 5-HT5A
7XOX GASR CCK2
8JJO ADRB2 β2
7XT9 5HT4R 5-HT4
7XJK GALR2 GAL2
7F1O DRD1 D1
7X2F DRD1 D1
7F6H BKRB2 B2
7W0O APJ apelin
8JMT AGRL3 ADGRL3
7EPT AGRD1 ADGRD1
7T6B S1PR2 S1P2
9DQH MRGRD MRGPRD
6LUQ DRD2 D2
9IZG LPAR1 LPA1
8T1W GPR6 GPR6
9IJA T2R14 TAS2R14
6RZ9 CLTR2 CysLT2
9IYA GPR55 GPR55
5NJ6 PAR2 PAR2
7WUQ AGRG2 ADGRG2
3PBL DRD3 D3
7WU5 AGRF1 ADGRF1
2J4Y OPSD Rhodopsin
4MQT ACM2 M2
7X8S GLP1R GLP-1
6FFH GRM5 mGlu5
3ODU CXCR4 CXCR4
6D26 PD2R2 DP2
7S0G ADRB1 β1
7W55 NMUR2 NMU2
7W0L APJ apelin
7XJL GALR2 GAL2
7X9A NPY1R Y1
9CHV ADRB2 β2
8X5X HRH1 H1
6KJV GLP1R GLP-1
7WBJ VIPR2 VPAC2
7RGP GLP1R GLP-1
7XT8 5HT4R 5-HT4
7WKD TRFR TRH1
7X2D DRD1 D1
7SQO OX2R OX2
7DD6 CASR CaS
5UZ7 CALCR CT
7UM7 5HT5A 5-HT5A
7S0F ADRB1 β1
7F24 DRD1 D1
7WU2 AGRD1 ADGRD1
7W0N APJ apelin
8T6J GRM5 mGlu5
9IY8 GPR55 GPR55
7X2C DRD1 D1
7XJI ADRB3 β3
7EQ1 AGRG5 ADGRG5
7F23 DRD1 D1
7RBT GIPR GIP
7VBH GLP1R GLP-1
8T7H GRM5 mGlu5
9IVG GLP1R GLP-1
6FJ3 PTH1R PTH1
7XTC 5HT7R 5-HT7
7XBD GALR2 GAL2
9IVM GLP1R GLP-1
6RZ7 CLTR2 CysLT2
8T1V GPR6 GPR6
8X5Y HRH1 H1
7RA3 GIPR GIP
7XTB 5HT6R 5-HT6
7XOU CCKAR CCK1
7U2L OPRM μ
7WU4 AGRF1 ADGRF1
7TUZ GP183 GPR183
7W56 NMUR1 NMU1
7W53 NMUR1 NMU1
7T9N TSHR TSH
7VV4 MRGX2 MRGPRX2
7XKF AGRG2 ADGRG2
7RM5 AA2AR A2A
7X9Y CCR3 CCR3
7XMT SSR4 SST4
7QVM OXYR OT
7X2V AGRF1 ADGRF1
7ZBC OPSD Rhodopsin
7VVJ PTH1R PTH1
7VIE S1PR1 S1P1
7SRR 5HT2B 5-HT2B
8W77 O52E4 OR52E4
7VIF S1PR1 S1P1
7R0C V2R V2
7XMS SSR4 SST4
7VIH S1PR1 S1P1
6DRY 5HT2B 5-HT2B
7XTQ GPBAR GPBA
6LPK AA2AR A2A
8GNG AA2AR A2A
4Z9G CRFR1 CRF1
8TB7 GPR61 GPR61
7XN9 SSR2 SST2
8A6E OPSD Rhodopsin
7WY5 AGRL3 ADGRL3
6IGL EDNRB ETB
7XMR SSR2 SST2
4YAY AGTR1 AT1
8DCS ADRB1 β1
7WXW AGRF1 ADGRF1
7YP7 AGRG2 ADGRG2
8GED ADRB2 β2
7WJ5 SSR2 SST2
8A6D OPSD Rhodopsin
7XP5 T2R46 TAS2R46
7XAV SSR2 SST2
5VEX GLP1R GLP-1
5V56 SMO SMO
7W6P ADA2A α2A
8XBI GPR34 GPR34
7VVK PTH1R PTH1
7WY8 AGRL3 ADGRL3
7VVO PTH1R PTH1
7X1T TRFR TRH1
6UVA CALRL calcitonin-like
7VFX FPR1 FPR1
7X1U TRFR TRH1
7XBX CX3C1 CX3CR1
6ZFZ ACM1 M1
7WCM GP119 GPR119
7WU9 PE2R3 EP3
7YOO NPY2R Y2
7XKD AGRG2 ADGRG2
6ME6 MTR1B MT2
6TO7 OX1R OX1
8DPH 5HT2C 5-HT2C
2Y02 ADRB1 β1
6UUS CALRL calcitonin-like
7WCN GP119 GPR119
7DD7 CASR CaS
7VVM PTH1R PTH1
7WYB AGRL3 ADGRL3
7SRS 5HT2B 5-HT2B
7KNT CALRL calcitonin-like
7T2H OPRM μ
7X10 AGRL3 ADGRL3
6PRZ ADRB2 β2
7XW5 TSHR TSH
7DGD GRM1 mGlu1
8A6C OPSD Rhodopsin
7WY0 AGRF1 ADGRF1
8DCR ADRB1 β1
7TS0 CRFR2 CRF2
7WZ7 AGRF1 ADGRF1
7UTZ TSHR TSH
7F1T CCR5 CCR5
7VIG S1PR1 S1P1
3VG9 AA2AR A2A
7Y24 SSR2 SST2
7BR3 GNRHR GnRH1
8EA0 ACM3 M3
7XZ5 GP119 GPR119
7WZ4 GPR88 GPR88
8DPG 5HT2C 5-HT2C
6ME8 MTR1B MT2
7XAU SSR2 SST2
7XBW CX3C1 CX3CR1
7Y26 SSR2 SST2
6TPK OXYR OT
7E6T CASR CaS
6K41 ADA2B α2B
8EFQ OPRM μ
7T90 ACM2 M2
8HDO AA2BR A2B
8EFO OPRM μ
7T8X ACM2 M2
7T96 ACM2 M2
7YK6 RL3R2 RXFP4
7Y65 C5AR1 C5a1
6K42 ADA2B α2B
7F8Y CCKAR CCK1
8E9X ACM4 M4
8TAO GRM5 mGlu5
7YU6 LPAR1 LPA1
7YU3 LPAR1 LPA1
8HAF PTH1R PTH1
8HAO PTH1R PTH1
7Y89 GPR17 GPR17
7YU8 LPAR1 LPA1
7Y67 C5AR1 C5a1
7T94 ACM2 M2
8WVV LGR4 LGR4
8WM9 FZD4 FZD4
7XK2 HCAR2 HCA2
8I2H FSHR FSH
8E9Z ACM3 M3
8GY7 ACTHR MC2
8F76 O51E2 OR51E2
6PS0 ADRB2 β2
6TOD OX1R OX1
8HCX EDNRB ETB
7CX3 PE2R2 EP2
8HSC GPR20 GPR20
8XVJ EDNRA ETA
6TQ6 OX1R OX1
8T8M GRM5 mGlu5
7L0S NTR1 NTS1
8EF5 OPRM μ
8E3X PACR PAC1
8WPG CASR CaS
7VV6 MRGX2 MRGPRX2
7LCK GLP1R GLP-1
7CA3 GABR2 GABAB2
7YK7 RL3R2 RXFP4
8HBD EDNRB ETB
6WH4 5HT2A 5-HT2A
8F7X OPRX NOP
6PS1 ADRB2 β2
8ID4 FFAR4 FFA4
8ID9 FFAR4 FFA4
8F7S OPRD δ
8HS3 GPR20 GPR20
8HIX GPR21 GPR21
7CA5 GABR2 GABAB2
8HDP AA2BR A2B
6D27 PD2R2 DP2
5YHL PE2R4 EP4
6ME2 MTR1A MT1
8F7R OPRM μ
8FN1 NTR1 NTS1
5ZHP ACM3 M3
8EFB OPRM μ
8WG9 GRM4 mGlu4
8ID3 FFAR4 FFA4
8X0E GRM5 mGlu5
7YU5 LPAR1 LPA1
6TPJ OX2R OX2
8HJ0 GPR21 GPR21
8I2G FSHR FSH
8WCC TAAR1 TA1
8ID6 FFAR4 FFA4
8EF6 OPRM μ
8X0D GRM5 mGlu5
8EFL OPRM μ
8F7Q OPRM μ
8H8J GPR35 GPR35
8XFS LGR4 LGR4
7DGE GRM1 mGlu1
8DWG MRGX1 MRGPRX1
8DWC MRGX1 MRGPRX1
7KNU CALRL calcitonin-like
8G59 FFAR4 FFA4
7SUS APJ apelin
5UIG AA2AR A2A
7W40 GRPR BB2
8E3Y VIPR1 VPAC1
8E3Z VIPR1 VPAC1
4Z35 LPAR1 LPA1
8GHV CNR1 CB1
8DZQ OPRK κ
8FLQ PTH1R PTH1
8XVK EDNRA ETA
8IY5 EDNRB ETB
7CUM GABR2 GABAB2
7YDH AGRE5 ADGRE5
8IBU MTLR motilin
8GEE ADRB2 β2
5A8E ADRB1 β1
8CIC AA2AR A2A
7Y36 PTH1R PTH1
8GEH ADRB2 β2
6TQ7 OX1R OX1
8GW8 PTH1R PTH1
8IUL PF2R FP
8J1A GPR84 GPR84
8HMP GPR52 GPR52
7YM8 ADA1A α1A
8JR9 PTH1R PTH1
8EIT FFAR1 FFA1
6PS2 ADRB2 β2
8FLR PTH1R PTH1
8IUK PF2R FP
7ZL9 HCAR2 HCA2
5IU8 AA2AR A2A
7Y64 C5AR1 C5a1
8F2B CALCR CT
7DDZ NPY2R Y2
7XV3 GP174 GPR174
8IW1 TAAR9 TAAR9
7YAC SSR2 SST2
4DAJ ACM3 M3
8IBV MTLR motilin
7Y1F OPRK κ
8H4I FFAR4 FFA4
8UGW AA2AR A2A
8JD6 GRM4 mGlu4
6BD4 FZD4 FZD4
7TRQ ACM4 M4
4BUO NTR1 NTS1
6AK3 PE2R3 EP3
6PS3 ADRB2 β2
7YMH ADA1A α1A
7W41 GRPR BB2
8JRV GLR glucagon
7YDM AGRE5 ADGRE5
5VEW GLP1R GLP-1
8XVL EDNRA ETA
8FU6 GLR glucagon
8IUM PF2R FP
7Y3G GPR12 GPR12
8J19 GPR84 GPR84
8IWM TAAR9 TAAR9
8JD3 GRM2 mGlu2
8HK5 C5AR1 C5a1
7VOD 5HT2A 5-HT2A
7XY6 AA2BR A2B
6FK8 OPSD Rhodopsin
7YDJ AGRE5 ADGRE5
8J18 GPR84 GPR84
3V2Y S1PR1 S1P1
7XXH P2RY1 P2Y1
8GUR CNR2 CB2
8DZR OPRK κ
7EPB GRM2 mGlu2
2YDV AA2AR A2A
6MH8 AA2AR A2A
8IW4 TAAR9 TAAR9
8DZP OPRK κ
8GUS CNR2 CB2
8H0P NMBR BB1
6WQA AA2AR A2A
7TRK ACM4 M4
6W25 MC4R MC4
7XXI P2Y12 P2Y12
6NBF PTH1R PTH1
7ZLY HCAR2 HCA2
7YDP AGRE5 ADGRE5
7XKA ADRB2 β2
8HS2 GPR20 GPR20
8JLZ 5HT6R 5-HT6
8EJK FFAR1 FFA1
8HK3 C3AR C3a
8JRU GLR glucagon
7XWO NK2R NK2
2I37 OPSD Rhodopsin
8H0Q GRPR BB2
8GUT CNR2 CB2
4Z36 LPAR1 LPA1
8ZMG 5HT2A 5-HT2A
8GGN ADRB2 β2
8IA2 C5AR1 C5a1
8IJA HCAR2 HCA2
8W89 TAAR1 TA1
8I9S C3AR C3a
8I9L C3AR C3a
8I95 C3AR C3a
8HVI GP132 GPR132
8HQE GP132 GPR132
8HOC HRH4 H4
8HNK CXCR3 CXCR3
8GDB PE2R4 EP4
8GD9 PE2R4 EP4
8GCM PE2R4 EP4
8FX5 ACM4 M4
8JZ7 HCAR2 HCA2
8IRJ GP179 GPR179
8WC4 TAAR1 TA1
8ITM GIPR GIP
6TPG OX2R OX2
8WC7 TAAR1 TA1
6UO8 GABR2 GABAB2
8JLR TAAR1 TA1
8KGK GPR61 GPR61
8JLJ TAAR1 TA1
8XBH GPR34 GPR34
8IKJ AGRE5 ADGRE5
8HJ1 GPR21 GPR21
8U1U CCR8 CCR8
8FYX 5HT1A 5-HT1A
8WCA TAAR1 TA1
8W88 TAAR1 TA1
8SG1 CML1 chemerin
8JLK TAAR1 TA1
8J6P HCAR2 HCA2
8GGV ADRB2 β2
7SIL CASR CaS
8K2X CXCR3 CXCR3
8IHH HCAR2 HCA2
8KH4 GP161 GPR161
6TPN OX2R OX2
8IHJ HCAR3 HCA3
8ITL GIPR GIP
8GG7 ADRB2 β2
8HPT C5AR1 C5a1
8THK ADA1A α1A
3DQB OPSD Rhodopsin
7V9L GHRHR GHRH
6KO5 GHSR ghrelin
8JZZ C5AR1 C5a1
8WC6 TAAR1 TA1
4XEE NTR1 NTS1
8IEI GP156 GPR156
8FYL 5HT1A 5-HT1A
8JLP TAAR1 TA1
7EPC GRM7 mGlu7
8GGY ADRB2 β2
8GGZ ADRB2 β2
8IOD MC5R MC5
8YZK GPC5D GPRC5D
8PM2 TAA7F TAAR7F
8JLQ TAAR1 TA1
8ZMF 5HT2C 5-HT2C
8WC3 TAAR1 TA1
8GE1 ADRB2 β2
8WC8 TAAR1 TA1
8WPU CASR CaS
8JIU GLR glucagon
8GGJ ADRB2 β2
8JSP 5HT1A 5-HT1A
8W8Q GP101 GPR101
8U26 NK1R NK1
7YFD HRH4 H4
8JIT GLR glucagon
8GGM ADRB2 β2
8W8B 5HT1A 5-HT1A
8GGL ADRB2 β2
6PS4 ADRB2 β2
6ZDV AA2AR A2A
5IUB AA2AR A2A
8FYE 5HT1A 5-HT1A
8GGT ADRB2 β2
7SIN CASR CaS
8SAI GPR34 GPR34
8GCP PE2R4 EP4
8GGK ADRB2 β2
8JLO TAAR1 TA1
8TB0 GPR61 GPR61
8GFV ADRB2 β2
8GE8 ADRB2 β2
5JQH ADRB2 β2
8GGB ADRB2 β2
7F8X CCKAR CCK1
8GE9 ADRB2 β2
8GE6 ADRB2 β2
8POK HRH2 H2
7TUY GP183 GPR183
4BWB NTR1 NTS1
8IYH HCAR2 HCA2
8X0H GRM5 mGlu5
5XEZ GLR glucagon
6UO9 GABR2 GABAB2
8GG8 ADRB2 β2
8GE3 ADRB2 β2
8IQ4 PF2R FP
7E6U CASR CaS
8GEJ ADRB2 β2
8JER HCAR2 HCA2
8JXT HRH4 H4
8GE5 ADRB2 β2
8JGG MRGX1 MRGPRX1
8J9N FZD1 FZD1
8IU2 OPSR OPN1LW
8X0F GRM5 mGlu5
8PKM 5HT1A 5-HT1A
8GG9 ADRB2 β2
9D3G CCR6 CCR6
8GGE ADRB2 β2
7SIM CASR CaS
8GFW ADRB2 β2
6M9T PE2R3 EP3
8GG2 ADRB2 β2
6E59 NK1R NK1
8GEA ADRB2 β2
8JT6 5HT1A 5-HT1A
5JTB AA2AR A2A
8KGG P2Y10 P2RY10
7VV0 MRGX2 MRGPRX2
8C9W AA2AR A2A
8GEB ADRB2 β2
8GG3 ADRB2 β2
8I7W HCAR2 HCA2
8J6L HCAR2 HCA2
8GGA ADRB2 β2
8JXX HRH4 H4
8I7V HCAR2 HCA2
7YMJ ADA1A α1A
8IZ4 GPR34 GPR34
8JGF MRGX1 MRGPRX1
8IYW HCAR2 HCA2
6UOA GABR2 GABAB2
8JHI FZD3 FZD3
8GG5 ADRB2 β2
8X0C GRM5 mGlu5
8K9K OPRM μ
8JPP SUCR1 succinate
8KFZ CCR8 CCR8
8GGQ ADRB2 β2
6MEO CCR5 CCR5
8J21 FFAR3 FFA3
8J20 FFAR3 FFA3
8GG0 ADRB2 β2
8JBF NK3R NK3
8JXV HRH4 H4
7EPE GRM2 mGlu2
8GH1 ADRB2 β2
8JBG NK3R NK3
8JCY GRM2 mGlu2
6PS5 ADRB2 β2
8PJK 5HT1A 5-HT1A
8QJ2 MC4R MC4
8GGP ADRB2 β2
8IQ6 PF2R FP
8GGS ADRB2 β2
8K9L OPRM μ
8IED GP156 GPR156
8SMV GP161 GPR161
8GE4 ADRB2 β2
7LCJ GLP1R GLP-1
4XES NTR1 NTS1
8GFY ADRB2 β2
6DS0 5HT2B 5-HT2B
6JOD AGTR2 AT2
8JHB FZD6 FZD6
8GEC ADRB2 β2
8IEP GP156 GPR156
6H7J ADRB1 β1
8IYX GPR34 GPR34
8X16 AA3R A3
8UNQ ADRB2 β2
7EWP GP158 GPR158
8U8F GPR3 GPR3
8XGR EDNRB ETB
7EWR GP158 GPR158
8X8L SSR5 SST5
8UO4 ADRB2 β2
8UWL 5HT2A 5-HT2A
8JPS ACKR1 ACKR1
8XOG GPER1 GPER
8XIP SSR1 SST1
8JCZ GRM2 mGlu2
8UH3 5HT1E 5-HT1E
6MET CCR5 CCR5
3NY8 ADRB2 β2
8V6U 5HT2A 5-HT2A
6FKC OPSD Rhodopsin
8UNS ADRB2 β2
8SZG CASR CaS
6WW2 FZD5 FZD5
8WP1 SUCR1 succinate
8WOG SUCR1 succinate
8XFP LGR4 LGR4
7M3F CASR CaS
8T3V FFAR1 FFA1
8X0G GRM5 mGlu5
8UGY 5HT1E 5-HT1E
8WST MCHR2 MCH2
8JCW GRM2 mGlu2
8WU1 CNR1 CB1
6PS7 AA2AR A2A
8X79 PI2R IP
9BJK OPRM μ
6LPL AA2AR A2A
8XOH GPER1 GPER
6H7L ADRB1 β1
6FKD OPSD Rhodopsin
6VJM GABR2 GABAB2
6GT3 AA2AR A2A
6PS8 MTR1A MT1
8XJL PF2R FP
8XIQ SSR3 SST3
6IIU TA2R TP
8GGW ADRB2 β2
8UO2 ADRB2 β2
6Z10 SUCR1 succinate
8UNT ADRB2 β2
8JCU GRM2 mGlu2
8GH0 ADRB2 β2
8UNV ADRB2 β2
8UO0 ADRB2 β2
8JCV GRM2 mGlu2
8XOR PAR1 PAR1
8T3O FFAR4 FFA4
5CGC GRM5 mGlu5
8WA3 GIPR GIP
8XOI GPER1 GPER
8XOJ GPER1 GPER
8X17 AA3R A3
8GGX ADRB2 β2
8WG8 GLR glucagon
6TOS OX1R OX1
6Z4Q NTR1 NTS1
8IEB GP156 GPR156
8UNU ADRB2 β2
8X2K GPR3 GPR3
8UNY ADRB2 β2
8XQP T2R14 TAS2R14
8U02 DRD2 D2
8XIO SSR1 SST1
8UNR ADRB2 β2
8J9O FZD1 FZD1
7M3E CASR CaS
8UNZ ADRB2 β2
8UO3 ADRB2 β2
7DTT CASR CaS
4J4Q OPSD Rhodopsin
2PED OPSD Rhodopsin
8XJM PF2R FP
8UNO ADRB2 β2
8XQN T2R14 TAS2R14
8VY7 T2R14 TAS2R14
8XIR SSR3 SST3
6N48 ADRB2 β2
8XJN TA2R TP
8WG7 GLP1R GLP-1
8WW2 GPR3 GPR3
8XGM CML2 chemerin 2
9ASB CASR CaS
9IIX T2R14 TAS2R14
8XQT T2R14 TAS2R14
8RQQ AA2AR A2A
8XGS KISSR kisspeptin
3NYA ADRB2 β2
9F34 DRD3 D3
9AVG CASR CaS
8TH4 AGTR1 AT1
8YW4 GIPR GIP
8YKX SUCR1 succinate
8K6M NPY1R Y1
7ARO AA2AR A2A
8YUV HRH3 H3
8YUU HRH3 H3
8JWY AA2AR A2A
9IIW T2R14 TAS2R14
9BQJ OPRM μ
6OS1 AGTR1 AT1
7DTW CASR CaS
6I9K B1B1U5 Rhodopsin
6O3C SMO SMO
8UXV O51G2 OR51G2
9BKK CCKAR CCK1
9CBM ADA2A α2A
4AMJ ADRB1 β1
8XZH APJ apelin
8ZSV TAAR1 TA1
8SZF CASR CaS
8XWP EDNRB ETB
7DTU CASR CaS
6GPS CCR2 CCR2
9AUC CALCR CT
8ZJD KISSR kisspeptin
8Y69 LGR4 LGR4
8TR2 GRM3 mGlu3
6IQL DRD4 D4
8YUT HRH2 H2
9IJE ADRB3 β3
9AXF CASR CaS
6Z4V NTR1 NTS1
9AVL CASR CaS
8WGB GRM2 mGlu2
8JT8 5HT2A 5-HT2A
8ZPS PRLHR PrRP
8K6N NPY2R Y2
7SHF GP158 GPR158
9BKJ CCKAR CCK1
8K3Z CXCR4 CXCR4
8K6O NPY1R Y1
8ZR5 GP119 GPR119
7M3G CASR CaS
5VRA AA2AR A2A
8TR0 GRM3 mGlu3
7PX4 AA2AR A2A
5ZBH NPY1R Y1
8WJX P2RY1 P2Y1
8YRG MRGX4 MRGPRX4
3EML AA2AR A2A
8Y52 BRS3 BB3
8JXS DRD1 D1
8XZI APJ apelin
8ZH8 QRFPR QRFP
6IIV TA2R TP
8RLN AA2AR A2A
8TH3 AGTR1 AT1
8U4S CXCR4 CXCR4
9AYF CASR CaS
8XVE EDNRB ETB
7PYR AA2AR A2A
8ZRK GP119 GPR119
6NI3 ADRB2 β2
8VHF GP119 GPR119
8JJP CML2 chemerin 2
8IKG CNR1 CB1
7SHE GP158 GPR158
8ZSP TAAR1 TA1
8XZF APJ apelin
8ZCJ SSR5 SST5
8JCX GRM2 mGlu2
8XQR T2R14 TAS2R14
8QW4 FZD3 FZD3
8ZBE SSR5 SST5
9F33 DRD3 D3
8XVI EDNRA ETA
7M3J CASR CaS
8YW5 GLR glucagon
8K4O Q76SF8 ORF74
2Y01 ADRB1 β1
8IKH CNR1 CB1
8IZB GP174 GPR174
6OYA OPSD Rhodopsin
9JR3 PTH1R PTH1
6N4B CNR1 CB1
8WWJ MCHR1 MCH1
8HNM CXCR3 CXCR3
8GTM CRFR1 CRF1
8GTI CRFR1 CRF1
8GTG CRFR1 CRF1
8FCZ OPSD Rhodopsin
8A2P AA2AR A2A
8E0G OPRM μ
8WWI MCHR1 MCH1
8UY0 OR2T2 OR2T2
8THL ADA1A α1A
8G94 S1PR1 S1P1
6GDG AA2AR A2A
1U19 OPSD Rhodopsin
8K4S MRGX4 MRGPRX4
6WZG SCTR secretin
7TD2 LPAR1 LPA1
8XML CCR8 CCR8
7WU3 AGRF1 ADGRF1
5WKT OPSD Rhodopsin
7T2G OPRM μ
8JD0 GRM2 mGlu2
7WV9 CNR1 CB1
8P12 OPSD Rhodopsin
5DYS OPSD Rhodopsin
9JR2 PTH1R PTH1
4ZUD AGTR1 AT1
7SR8 OX2R OX2
8JSO TAAR1 TA1
6OSA NTR1 NTS1
8XXU PD2R2 DP2
6TKO ADRB1 β1
8W87 TAAR1 TA1
6NBI PTH1R PTH1
7MBY CCKAR CCK1
7JJO ADRB1 β1
7XZ6 GP119 GPR119
7VDM MRGX2 MRGPRX2
9JKQ TAAR1 TA1
8XYD PTAFR PAF
9GYO GPBAR GPBA
6OY9 OPSD Rhodopsin
8GUQ CNR2 CB2
7W0M APJ apelin
7XW6 TSHR TSH
4PXF OPSD Rhodopsin
8TYW GPR6 GPR6
7CZ5 GHRHR GHRH
6OT0 SMO SMO
8JEI HCAR3 HCA3
6P9X CRFR1 CRF1
6DDF OPRM μ
8YN7 HRH3 H3
8YN4 HRH2 H2
8JD4 GRM2 mGlu2
8WWM MCHR1 MCH1
8HCQ EDNRA ETA
9IJ9 T2R14 TAS2R14
6NWE OPSD Rhodopsin
6QNO OPSD Rhodopsin
7TYX CALCR CT
8DWH MRGX1 MRGPRX1
8G2Y AGRF1 ADGRF1
7F58 MC4R MC4
6OIK ACM2 M2
5TZY FFAR1 FFA1
8XGO KISSR kisspeptin
8YN5 HRH3 H3
8YN9 HRH4 H4
6PWC NTR1 NTS1
6B3J GLP1R GLP-1
7S1M GLP1R GLP-1
9EPR B1B1U5 Rhodopsin
8JPF NTR1 NTS1
8JD2 GRM2 mGlu2
9EW2 FZD7 FZD7
6P9Y PACR PAC1
8JEF HCAR3 HCA3
8YN2 HRH1 H1
6OS9 NTR1 NTS1
8YN8 HRH3 H3
5WS3 OX2R OX2
8FD1 OPSD Rhodopsin
8H4K FFAR4 FFA4
7W57 NMUR2 NMU2
8GG4 ADRB2 β2
8IEQ GP156 GPR156
8JHY HCAR2 HCA2
8K8J CNR1 CB1
8IRV DRD5 D5
4U15 ACM3 M3
8HQN GP132 GPR132
8HN8 HRH4 H4
7YAE SSR2 SST2
8FYN AA2AR A2A
8XFT LGR4 LGR4
8J6Q HCAR2 HCA2
8H2G HCAR2 HCA2
8J6I HCAR2 HCA2
6WPW GLR glucagon
4GBR ADRB2 β2
8Y53 BRS3 BB3
7TRS ACM4 M4
8HA0 PTH1R PTH1
7WC8 5HT2A 5-HT2A
8UNL ADRB2 β2
8IJ3 HCAR2 HCA2
9IZF LPAR1 LPA1
6PS6 ADRB2 β2
5VBL APJ apelin
8SZH CASR CaS
8JD1 GRM2 mGlu2
4EIY AA2AR A2A
7F0T DRD1 D1
8GE2 ADRB2 β2
8WWL MCHR1 MCH1
8YW3 GLP1R GLP-1
4RWA OPRD δ
8IYS FFAR4 FFA4
8IY6 EDNRB ETB
9IQT HCAR2 HCA2
8ZSS TAAR1 TA1
8HJ2 GPR21 GPR21
7YKD CML1 chemerin
5KW2 FFAR1 FFA1
7WXU AGRF1 ADGRF1
8F0J CALCR CT
8F0K CALCR CT
7EJK ADA2A α2A
7DTV CASR CaS
6ME7 MTR1B MT2
8JGB MRGX1 MRGPRX1
5GLH EDNRB ETB
8WZ2 QRFPR QRFP
8JH7 FZD6 FZD6
8YKY T2R14 TAS2R14
8JPC NTR1 NTS1
8XOS PAR1 PAR1
7DB6 MTR1A MT1
2Y04 ADRB1 β1
7F1Z DRD1 D1
8UO1 ADRB2 β2
7F8W GASR CCK2
8TRD GRM3 mGlu3
6WWZ CCR6 CCR6
8XZG APJ apelin
4OO9 GRM5 mGlu5
7X8R GLP1R GLP-1
7V3Z CNR1 CB1
8F2A CALCR CT
8U4T CXCR4 CXCR4
8J6D C3AR C3a
8GFZ ADRB2 β2
8XBE GPR34 GPR34
6OS0 AGTR1 AT1
7F16 PTH2R PTH2
6WHA 5HT2A 5-HT2A
2YCY ADRB1 β1
7VKT LT4R1 BLT1
8GEI ADRB2 β2
8IJD HCAR2 HCA2
8GDZ ADRB2 β2
9CHX ADRB2 β2
8JBH NK3R NK3
5UEN AA1R A1
9EPP B1B1U5 Rhodopsin
8XZJ APJ apelin
8YNS MCHR1 MCH1
5D6L ADRB2 β2
8HQM GP132 GPR132
8H4L FFAR4 FFA4
7E2Y 5HT1A 5-HT1A
8J6R HCAR2 HCA2
8WRB GPR34 GPR34
6LRY EDNRB ETB
8JII HCAR2 HCA2
4X1H OPSD Rhodopsin
5IU4 AA2AR A2A
8S4D APJ apelin
5NM2 AA2AR A2A
2VT4 ADRB1 β1
5WF5 AA2AR A2A
5TE5 OPSD Rhodopsin
3C9L OPSD Rhodopsin
5N2S AA1R A1
6OS2 AGTR1 AT1
5NX2 GLP1R GLP-1
5WIV DRD4 D4
5X93 EDNRB ETB
5NDZ PAR2 PAR2
5NDD PAR2 PAR2
3OE9 CXCR4 CXCR4
6FFI GRM5 mGlu5
5IUA AA2AR A2A
6KUW ADA2C α2C
3AYN OPSD Rhodopsin
4XNV P2RY1 P2Y1
8JIQ GLR glucagon
4ZJ8 OX1R OX1
6FK6 OPSD Rhodopsin
5ZTY CNR2 CB2
7MT9 OPSD Rhodopsin
5O9H C5AR1 C5a1
5IU7 AA2AR A2A
4BV0 NTR1 NTS1
8JIM HCAR2 HCA2
6G79 5HT1B 5-HT1B
6D35 Q98SW5 SMO
5XRA CNR1 CB1
6IBB SUCR1 succinate
8JIR GLP1R GLP-1
6CMO OPSD Rhodopsin
5CGD GRM5 mGlu5
5TUD 5HT2B 5-HT2B
4BEY OPSD Rhodopsin
5DSG ACM4 M4
4U14 ACM3 M3
5EE7 GLR glucagon
1L9H OPSD Rhodopsin
5K2B AA2AR A2A
4MBS CCR5 CCR5
3AYM OPSD Rhodopsin
5MZJ AA2AR A2A
6Z66 NTR1 NTS1
5LWE CCR9 CCR9
8WVW LGR4 LGR4
5UNH AGTR2 AT2
5VAI G1SGD4 GLP-1
5DHG OPRX NOP
4DJH OPRK κ
4UHR AA2AR A2A
1HZX OPSD Rhodopsin
8JIP GLP1R GLP-1
2I36 OPSD Rhodopsin
5OLG AA2AR A2A
5UNF AGTR2 AT2
5T1A CCR2 CCR2
7WI6 GRM3 mGlu3
6GPX CCR2 CCR2
3V2W S1PR1 S1P1
8WGD GRM4 mGlu4
3CAP OPSD Rhodopsin
6ZG4 ACM1 M1
4RWS CXCR4 CXCR4
4S0V OX2R OX2
8JIL HCAR2 HCA2
5T04 NTR1 NTS1
4EA3 OPRX NOP
5OM1 AA2AR A2A
7BTS ADRB1 β1
4DKL OPRM μ
3ZEV NTR1 NTS1
6H7O ADRB1 β1
8HNL CXCR3 CXCR3
4QKX ADRB2 β2
8IHK HCAR3 HCA3
6HLO NK1R NK1
7BVQ ADRB1 β1
9IYB PD2R2 DP2
4XT3 US28 US28
7UL5 SSR2 SST2
8ZX5 GPR55 GPR55
8YNT MCHR1 MCH1
6N51 GRM5 mGlu5
7B6W ADA1B α1B
8WVY LGR4 LGR4
3D4S ADRB2 β2
6KUX ADA2A α2A
9B9Z CNR1 CB1
5GLI EDNRB ETB
8WDT AA2AR A2A
6A94 5HT2A 5-HT2A
9K1C FFAR1 FFA1
6AKX CCR5 CCR5
8YN3 HRH2 H2
5ZKQ PTAFR PAF
6D9H AA1R A1
9J5V LPAR1 LPA1
2YDO AA2AR A2A
9DQJ MRGRD MRGPRD
9BA0 CNR1 CB1
9CHU ADRB2 β2
7WC4 5HT2A 5-HT2A
6D32 Q98SW5 SMO
4PHU FFAR1 FFA1
6ZDR AA2AR A2A
6LI1 GPR52 GPR52
8Y45 OPRD δ
4RWD OPRD δ
6PT0 CNR2 CB2
7EZC AA2AR A2A
6LML GLR glucagon
9K1D FFAR2 FFA2
6TOT OX1R OX1
6PB1 CRFR2 CRF2
8TF5 GPR6 GPR6
3NY9 ADRB2 β2
8P15 OPSD Rhodopsin
6KPC CNR2 CB2
2I35 OPSD Rhodopsin
8J46 O52E4 OR52E4
3ZPQ ADRB1 β1
9C1P CASR CaS
5XR8 CNR1 CB1
4QIM SMO SMO
7BU7 ADRB1 β1
6WIV GABR2 GABAB2
7MTQ GRM2 mGlu2
8TLM CCR8 CCR8
9AST XCR1 XCR1
6KPF CNR2 CB2
5YQZ GLR glucagon
9B9Y CNR1 CB1
6IBL ADRB1 β1
7WIH GRM3 mGlu3
7BU6 ADRB1 β1
6KPG CNR1 CB1
8ZRT EDNRB ETB
6AKY CCR5 CCR5
9EPQ B1B1U5 Rhodopsin
9IMA GPC5D GPRC5D
5OLV AA2AR A2A
6QZH CCR7 CCR7
6K1Q EDNRB ETB
8ZX4 GPR55 GPR55
5OLH AA2AR A2A
6KUY ADA2A α2A
8WWK MCHR1 MCH1
6OFJ OPSD Rhodopsin
6TQ9 OX1R OX1
6RNK SUCR1 succinate
4K5Y CRFR1 CRF1
8YIC S1PR1 S1P1
6Z8N NTR1 NTS1
6W2Y GABR1 GABAB1
2HPY OPSD Rhodopsin
8XGU KISSR kisspeptin
8WVU LGR4 LGR4
5OM4 AA2AR A2A
6ZA8 NTR1 NTS1
6VN7 VIPR1 VPAC1
6OMM FPR2 FPR2/ALX
6XBK SMO SMO
6M1H PACR PAC1
8IHF HCAR2 HCA2
8IHB HCAR2 HCA2
7MTA OPSD Rhodopsin
8I9A C3AR C3a
5DGY OPSD Rhodopsin
8IA7 GASR CCK2
8K5D HCAR2 HCA2
8IJB HCAR2 HCA2
8HTI O52E4 OR52E4
8HNN CXCR3 CXCR3
8HN1 ADA1A α1A
8GDC PE2R3 EP3
8G05 GPR84 GPR84
6X19 GLP1R GLP-1
7CKX DRD1 D1
6XBL SMO SMO
7D3S SCTR secretin
7LJC DRD1 D1
7L0Q NTR1 NTS1
7JV5 DRD1 D1
5D5A ADRB2 β2
6VI4 OPRK κ
7MTR GRM2 mGlu2
4LDE ADRB2 β2
5UNG AGTR2 AT2
6OL9 ACM5 M5
7D76 AGRG3 ADGRG3
6PEL OPSD Rhodopsin
6XBM SMO SMO
6XOX GLP1R GLP-1
5ZKP PTAFR PAF
7L1U OX2R OX2
7YXA S1PR5 S1P5
8WKY MC4R MC4
6LFO CXCR2 CXCR2
7D77 AGRG3 ADGRG3
7BZ2 ADRB2 β2
7CMU DRD3 D3
6MXT ADRB2 β2
7CKZ DRD1 D1
6VCB GLP1R GLP-1
7DHI ADRB2 β2
7LJD DRD1 D1
6WGT 5HT2A 5-HT2A
7D68 GLP2R GLP-2
6WI9 SCTR secretin
7AD3 STE2 STE2
6C1Q C5AR1 C5a1
7WC6 5HT2A 5-HT2A
7SK8 ACKR3 ACKR3
6XBJ SMO SMO
8WKZ MC4R MC4
3ZPR ADRB1 β1
6X1A GLP1R GLP-1
8WMA FZD4 FZD4
6M1I PACR PAC1
5YC8 ACM2 M2
5V54 5HT1B 5-HT1B
7C7Q GABR2 GABAB2
7CFM GPBAR GPBA
7JVP DRD1 D1
8W1V ADRB2 β2
7L0R NTR1 NTS1
5D5B ADRB2 β2
6HLL NK1R NK1
7JVR DRD2 D2
3KJ6 ADRB2 β2
6LN2 GLP1R GLP-1
7BW0 GPBAR GPBA
7L0P NTR1 NTS1
6PH7 OPSD Rhodopsin
8CU6 AA2AR A2A
7JVQ DRD1 D1
5K2C AA2AR A2A
7CKW DRD1 D1
7CFN GPBAR GPBA
6WHC GLR glucagon
7E2X 5HT1A 5-HT1A
7CKY DRD1 D1
6X18 GLP1R GLP-1
7DHR ADRB2 β2
6KQI CNR1 CB1
6LI3 GPR52 GPR52
7ZI0 SMO SMO
7C2E GLP1R GLP-1
8FD0 OPSD Rhodopsin
5MZP AA2AR A2A
8A2O AA2AR A2A
3VW7 PAR1 PAR1
6DRX 5HT2B 5-HT2B
7S15 GLP1R GLP-1
8IW9 TAAR9 TAAR9
7RKN US28 US28
7X5H 5HT5A 5-HT5A
2G87 OPSD Rhodopsin
7XW9 TRFR TRH1
3C9M OPSD Rhodopsin
8GGR ADRB2 β2
8X64 HRH1 H1
9IJD ADRB3 β3
7RYC OXYR OT
8JHC FZD3 FZD3
8T3S FFAR2 FFA2
8YY8 FZD7 FZD7
7YS6 5HT6R 5-HT6
4NC3 5HT2B 5-HT2B
8JIS GLP1R GLP-1
7Y66 C5AR1 C5a1
6FK9 OPSD Rhodopsin
6KNM APJ apelin
8GEG ADRB2 β2
7WI8 GRM3 mGlu3
7SK3 ACKR3 ACKR3
7E33 5HT1E 5-HT1E
8GGU ADRB2 β2
8IRT DRD3 D3
6ME9 MTR1B MT2
8U4P CXCR4 CXCR4
7MTB OPSD Rhodopsin
8J22 FFAR2 FFA2
5K2D AA2AR A2A
8X3L CNR2 CB2
8UNW ADRB2 β2
8IHI HCAR2 HCA2
7CRH DRD1 D1
5EN0 OPSD Rhodopsin
8WGC GRM2 mGlu2
7WC9 5HT2A 5-HT2A
8WVX LGR4 LGR4
8GG1 ADRB2 β2
6E3Y CALRL calcitonin-like
7EJX GPR88 GPR88
5N2R AA2AR A2A
8WSS MCHR1 MCH1
5L7D SMO SMO
4Z34 LPAR1 LPA1
7C6A AGTR2 AT2
2YCX ADRB1 β1
5NLX AA2AR A2A
8HMV GPR21 GPR21
7VUG GP139 GPR139
8X8N SSR5 SST5
7RG9 GLP1R GLP-1
8W8A TAAR1 TA1
6LPB PACR PAC1
5WIU DRD4 D4
5TVN 5HT2B 5-HT2B
7D7M PE2R4 EP4
9EPO FZD7 FZD7
8YN6 HRH3 H3
8YKV SUCR1 succinate
4A4M OPSD Rhodopsin
6PT3 OPRD δ
7U2K OPRM μ
7YU4 LPAR1 LPA1
7TMW RXFP1 RXFP1
7T9M TSHR TSH
7UL3 HRH2 H2
5YWY PE2R4 EP4
7L1V OX2R OX2
7MT8 OPSD Rhodopsin
4BVN ADRB1 β1
5L7I SMO SMO
8UHB TAAR1 TA1
7Y27 SSR2 SST2
4GPO ADRB1 β1
7W3Z GRPR BB2
8FLU PTH1R PTH1
8IRU DRD4 D4
6FKB OPSD Rhodopsin
7WC5 5HT2A 5-HT2A
3OE0 CXCR4 CXCR4
8DPI 5HT2C 5-HT2C
5WQC OX2R OX2
5W0P OPSD Rhodopsin
7EO4 S1PR1 S1P1
8ITF TAAR9 TAAR9
6TP6 OX1R OX1
5OLZ AA2AR A2A
9C2F CASR CaS
7E14 GLP1R GLP-1
5K2A AA2AR A2A
4PY0 P2Y12 P2Y12
7X9C NPY4R Y4
8F7W OPRK κ
7XKE AGRG2 ADGRG2
8JXR DRD1 D1
8U4R CXCR4 CXCR4
8KEX MRGX4 MRGPRX4
7Y13 MRGRD MRGPRD
8WC5 TAAR1 TA1
6E67 ADRB2 β2
7F1S CCR5 CCR5
7XY7 AA2BR A2B
5OLO AA2AR A2A
8VY9 T2R14 TAS2R14
5C1M OPRM μ
6ORV GLP1R GLP-1
7RMH NK1R NK1
5UIW CCR5 CCR5
8GGI ADRB2 β2
7TRY CRFR2 CRF2
7DFL HRH1 H1
7TYY CALCR CT
7XOV CCKAR CCK1
4XT1 US28 US28
8JPB NTR1 NTS1
8K4N GPR34 GPR34
8FEG OPRK κ
8T3Q FFAR4 FFA4
8XBG GPR34 GPR34
7EUO FPR1 FPR1
8J6J HCAR2 HCA2
5XPR EDNRB ETB
8FLT PTH1R PTH1
7DFP DRD2 D2
6VMS DRD2 D2
4N4W SMO SMO
5TZR FFAR1 FFA1
8JD5 GRM2 mGlu2
6LMK GLR glucagon
5V57 SMO SMO
8GG6 ADRB2 β2
6H7N ADRB1 β1
7TYL CALCR CT
9CBL ADA2A α2A
8WWH MCHR1 MCH1
6ZIN NTR1 NTS1
7PIU MC4R MC4
8XOF GPER1 GPER
7WUJ AGRG4 ADGRG4
8TRC GRM3 mGlu3
7XK8 NMUR2 NMU2
8W8R GP101 GPR101
4GRV NTR1 NTS1
7Y35 PTH1R PTH1
8ZFJ E7FEL0 GPR4
6C1R C5AR1 C5a1
8GNE AA2AR A2A
5XF1 GLR glucagon
2Z73 OPSD Rhodopsin
7EPF GRM2 mGlu2
5TGZ CNR1 CB1
2YCW ADRB1 β1
5DHH OPRX NOP
8GAG CNR1 CB1
8W8S GP101 GPR101
7XJJ GALR1 GAL1
8XWQ EDNRB ETB
7JNI AGTR2 AT2
7VUY MRGX2 MRGPRX2
7CMV DRD3 D3
8KFY CCR8 CCR8
4L6R GLR glucagon
4PXZ P2Y12 P2Y12
8FYT 5HT1A 5-HT1A
3QAK AA2AR A2A
6ZG9 ACM1 M1
7ZBE OPSD Rhodopsin
7P02 NK1R NK1
6TQ4 OX1R OX1
7XNA SSR2 SST2
7V68 ACM4 M4
4UG2 AA2AR A2A
8WWN MCHR1 MCH1
4EJ4 OPRD δ
8J24 FFAR2 FFA2
7EZM CCKAR CCK1
6AQF AA2AR A2A
8IRR DRD1 D1
3PDS ADRB2 β2
7YJ4 RL3R2 RXFP4
8RQL T2R14 TAS2R14
7TYI CALCR CT
4AMI ADRB1 β1
6DDE OPRM μ
7XJH ADRB3 β3
7UL2 NTR1 NTS1
1GZM OPSD Rhodopsin
8GDA PE2R4 EP4
6FK7 OPSD Rhodopsin
8IKL AGRE5 ADGRE5
7VVN PTH1R PTH1
8UNM ADRB2 β2
7UM5 5HT5A 5-HT5A
8IRS DRD2 D2
6NBH PTH1R PTH1
4QIN SMO SMO
4IAQ 5HT1B 5-HT1B
7C4S S1PR3 S1P3
8HK2 C3AR C3a
7EW0 S1PR1 S1P1
7LCI GLP1R GLP-1
7YFC HRH4 H4
7EPA GRM2 mGlu2
3PQR OPSD Rhodopsin
1F88 OPSD Rhodopsin
6U1N ACM2 M2
7W7E ADA2A α2A
9ERX CNR1 CB1
7WVY FPR2 FPR2/ALX
6N52 GRM5 mGlu5
8SZI CASR CaS
7F6I BKRB2 B2
3RZE HRH1 H1
8UNP ADRB2 β2
7XK9 ADRB2 β2
7NA7 GHSR ghrelin
7KH0 V2R V2
5X33 Q9WTK1 BLT1
8XJO TA2R TP
3UZA AA2AR A2A
8YKW SUCR1 succinate
8YNA HRH4 H4
8KFX CCR8 CCR8
8IY9 HCAR2 HCA2
8DPF 5HT2C 5-HT2C
8IWE TAAR9 TAAR9
3OE8 CXCR4 CXCR4
6PGS OPSD Rhodopsin
8E9W ACM3 M3
7EW3 S1PR3 S1P3
8GEF ADRB2 β2
6HLP NK1R NK1
7FIH LSHR LH
5XSZ Q08BG4 LPA6
7VOE 5HT2A 5-HT2A
8EJC FFAR1 FFA1
4ZWJ OPSD Rhodopsin
8XVH EDNRB ETB
8U4O CXCR4 CXCR4
7SK5 ACKR3 ACKR3
7UL4 OPRM μ
7VVL PTH1R PTH1
8FY8 5HT1A 5-HT1A
5G53 AA2AR A2A
6TP3 OX1R OX1
6B73 OPRK κ
5ZBQ NPY1R Y1
7WQ3 GALR1 GAL1
8IA8 C3AR C3a
8X7A PI2R IP
8U4N CXCR4 CXCR4
7KI1 GLP1R GLP-1
3UZC AA2AR A2A
7XTA 5HT4R 5-HT4
7TRP ACM4 M4
8ZPT PRLHR PrRP
8JLN TAAR1 TA1
7F6G AGTR1 AT1
5X7D ADRB2 β2
6LFM CXCR2 CXCR2
7TD1 LPAR1 LPA1
7Y15 MRGRD MRGPRD
8IOC MC3R MC3
4N6H OPRD δ
8U4Q CXCR4 CXCR4
8GE7 ADRB2 β2
7YON NPY2R Y2
8DZS OPRK κ
6FUF OPSD Rhodopsin
4O9R SMO SMO
2Y03 ADRB1 β1
8PWN AA2AR A2A
8UNN ADRB2 β2
8XXV PD2R2 DP2
7XP4 T2R46 TAS2R46
5F8U ADRB1 β1
8UYQ OR4D5 OR4D5
7F55 MC4R MC4
8X0B GRM5 mGlu5
8K4P Q76SF8 ORF74
8WC9 TAAR1 TA1
7EWL GP158 GPR158
8FLS PTH1R PTH1
7T9I TSHR TSH
8KH5 GP174 GPR174
7M8W PD2R2 DP2
3VGA AA2AR A2A
7XA3 CCR2 CCR2
6PB0 CRFR1 CRF1
6TP4 OX1R OX1
8ZJE KISSR kisspeptin
8TZQ DRD2 D2
8FMZ NTR1 NTS1
6V9S OX1R OX1
6FKA OPSD Rhodopsin
8INR MC5R MC5
8GGC ADRB2 β2
7TD0 LPAR1 LPA1
8ZQE GPR15 GPR15
7YIT OPRK κ
7LD3 AA1R A1
6LI0 GPR52 GPR52
8P13 OPSD Rhodopsin
5UVI AA2AR A2A
7S8P MRGX4 MRGPRX4
8GFX ADRB2 β2
8HQC C5AR1 C5a1
6KK7 GLP1R GLP-1
8TQB GRM3 mGlu3
3OE6 CXCR4 CXCR4
7VQX VIPR2 VPAC2
7TZF CALCR CT
4IB4 5HT2B 5-HT2B
8IW7 TAAR9 TAAR9
8XQL T2R14 TAS2R14
5CXV ACM1 M1
2R4S ADRB2 β2
8UXY OR1F1 OR1F1
8K2W CXCR3 CXCR3
7WUI AGRG2 ADGRG2
8I97 C3AR C3a
7XAT SSR2 SST2
7F8V GASR CCK2
5NM4 AA2AR A2A
6NIY CALCR CT
7Y14 MRGRD MRGPRD
7FIJ LSHR LH
8WRZ CNR1 CB1
8GGF ADRB2 β2
7YU7 LPAR1 LPA1
7RAN 5HT2A 5-HT2A
6LPJ AA2AR A2A
7EPD GRM2 mGlu2
7C7S GABR2 GABAB2
7C61 5HT1B 5-HT1B
4WW3 OPSD Rhodopsin
6LI2 GPR52 GPR52
8FN0 NTR1 NTS1
4IAR 5HT1B 5-HT1B
3PXO OPSD Rhodopsin
7V6A ACM4 M4
8HJ5 MRGX1 MRGPRX1
7F4D MSHR MC1
4JKV SMO SMO
5TE3 OPSD Rhodopsin
7Y12 MRGRD MRGPRD
8GGO ADRB2 β2
8JWZ AA2AR A2A
7P00 NK1R NK1
6Z4S NTR1 NTS1
3UON ACM2 M2
3OAX OPSD Rhodopsin
8JXW HRH4 H4
8ZSJ TAAR1 TA1
8E9Y ACM3 M3
8XJK PF2R FP
8XQS T2R14 TAS2R14
7DW9 V2R V2
7O7F CCR5 CCR5
3SN6 ADRB2 β2
8UNX ADRB2 β2
7FIN GIPR GIP
6OIJ ACM1 M1
7V69 ACM4 M4
8WCB TAAR1 TA1
6DRZ 5HT2B 5-HT2B
6BQG 5HT2C 5-HT2C
8JHN HCAR2 HCA2
8ID8 FFAR4 FFA4
8J23 FFAR2 FFA2
8XQO T2R14 TAS2R14
4OR2 GRM1 mGlu1
6LFL CXCR2 CXCR2
8JPN SUCR1 succinate
6ME5 MTR1A MT1
4NTJ P2Y12 P2Y12
7XP6 T2R46 TAS2R46
6BQH 5HT2C 5-HT2C
2YCZ ADRB1 β1
2X72 OPSD Rhodopsin
7WIG SSR2 SST2
6YVR NTR1 NTS1
 
N-term
 TM1
 ICL1
 TM2
 ECL1
 TM3
 ICL2
 TM4
 ECL2
 TM5
 ICL3
 TM6
 ECL3
 TM7
 H8
 C-term
 
 
 
N-term
 
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
 
 
 
TM5
 
 
 
 
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
N-term
 
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
 
 
 
 
 
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
 
 
ICL3
 
TM6
 
ECL3
 
TM7
 
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
C-term
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
TM1
 
ICL1
 
 
 
TM2
 
ECL1
 
 
 
 
 
TM3
 
ICL2
 
 
 
TM4
 
ECL2
 
 
 
TM5
 
ICL3
 
 
 
 
 
TM6
 
ECL3
 
 
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
N-term
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
TM1
 
 
 
 
ICL1
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
TM2
 
 
 
 
ECL1
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
TM3
 
 
 
 
 
 
 
 
ICL2
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
TM4
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
ECL2
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
TM5
 
ICL3
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
TM6
 
 
ECL3
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
TM7
 
 
 
 
 
 
 
 
 
 
 
 
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
 
 
 
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
 
 
 
 
 
TM5
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
ICL3
 
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
N-term
 
 
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
 
 
 
 
TM5
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
ICL3
 
 
TM6
 
ECL3
 
TM7
 
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
 
 
ECL2
 
 
 
 
 
TM5
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
ICL3
 
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
N-term
 
 
 
 
 
 
 
 
 
TM1
 
ICL1
 
 
 
TM2
 
ECL1
 
 
 
TM3
 
ICL2
 
TM4
 
ECL2
 
 
 
TM5
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
ICL3
 
TM6
 
ECL3
 
 
 
 
 
TM7
 
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
N-term
 
 
 
TM1
 
ICL1
 
 
 
TM2
 
ECL1
 
 
 
TM3
 
ICL2
 
TM4
 
ECL2
 
 
 
 
TM5
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
ICL3
 
 
 
TM6
 
ECL3
 
 
 
 
 
TM7
 
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
N-term
 
 
 
TM1
 
ICL1
 
TM2
 
ECL1
 
 
 
TM3
 
ICL2
 
TM4
 
ECL2
 
 
 
TM5
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
ICL3
 
 
 
 
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
N-term
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
TM1
 
 
 
 
ICL1
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
TM2
 
 
 
 
ECL1
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
TM3
 
 
 
 
 
 
 
 
ICL2
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
TM4
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
ECL2
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
TM5
 
ICL3
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
TM6
 
 
ECL3
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
TM7
 
 
 
 
 
 
 
 
 
 
 
 
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
N-term
 
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
 
 
 
 
TM5
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
ICL3
 
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
 
 
 
 
 
 
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
 
 
 
TM5
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
ICL3
 
 
TM6
 
ECL3
 
TM7
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
TM1
 
ICL1
 
 
 
TM2
 
ECL1
 
 
 
 
 
TM3
 
ICL2
 
 
 
TM4
 
ECL2
 
 
 
TM5
 
ICL3
 
 
 
 
 
TM6
 
ECL3
 
 
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
N-term
 
 
 
TM1
 
ICL1
 
 
 
TM2
 
 
ECL1
 
TM3
 
ICL2
 
TM4
 
 
 
ECL2
 
 
TM5
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
ICL3
 
 
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
 
 
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
 
 
 
TM5
 
 
 
 
 
ICL3
 
TM6
 
ECL3
 
TM7
 
 
 
 
 
 
 
 
 
 
 
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
 
 
 
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
 
 
TM3
 
ICL2
 
TM4
 
ECL2
 
 
 
 
 
TM5
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
ICL3
 
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
C-term
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
 
 
 
 
TM5
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
ICL3
 
 
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
N-term
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
TM1
 
 
 
ICL1
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
TM2
 
 
 
ECL1
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
TM3
 
 
 
 
 
 
 
 
ICL2
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
TM4
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
ECL2
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
TM5
 
 
 
 
 
 
ICL3
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
TM6
 
 
 
ECL3
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
TM7
 
 
 
 
 
 
 
 
 
 
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
 
 
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
 
N-term
 
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
 
 
ECL2
 
 
 
 
 
TM5
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
ICL3
 
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
 
 
 
TM5
 
 
 
 
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
 
 
 
 
 
 
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
 
 
TM5
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
ICL3
 
 
 
 
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
C-term
 
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
 
 
 
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
 
 
 
 
 
TM5
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
ICL3
 
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
N-term
 
 
 
TM1
 
ICL1
 
 
 
TM2
 
 
ECL1
 
TM3
 
ICL2
 
TM4
 
 
 
ECL2
 
 
TM5
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
ICL3
 
 
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
 
 
 
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
 
 
 
 
TM5
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
ICL3
 
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
 
 
 
TM5
 
 
 
 
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
TM1
 
ICL1
 
TM2
 
ECL1
 
 
 
TM3
 
ICL2
 
TM4
 
ECL2
 
 
 
 
TM5
 
 
 
 
 
ICL3
 
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
 
 
 
TM5
 
 
 
ICL3
 
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
 
 
 
 
 
 
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
C-term
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
TM1
 
ICL1
 
 
 
TM2
 
ECL1
 
 
 
 
 
TM3
 
ICL2
 
 
 
TM4
 
ECL2
 
 
 
TM5
 
ICL3
 
 
 
 
 
TM6
 
ECL3
 
 
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
 
 
 
TM5
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
ICL3
 
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
N-term
 
TM1
 
ICL1
 
 
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
 
 
ECL3
 
TM7
 
H8
 
C-term
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
 
 
 
 
ICL3
 
TM6
 
ECL3
 
 
 
TM7
 
H8
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
 
 
TM3
 
ICL2
 
TM4
 
ECL2
 
 
 
 
 
 
 
TM5
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
ICL3
 
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
 
 
 
TM5
 
 
 
ICL3
 
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
N-term
 
 
 
 
 
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
 
 
 
 
 
 
 
 
 
 
 
 
TM6
 
 
 
 
 
 
 
 
 
 
 
ECL3
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
TM7
 
 
 
 
 
 
 
H8
 
 
 
 
 
 
 
 
C-term
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
C-term
 
 
 
 
 
 
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
 
 
TM5
 
 
 
 
 
ICL3
 
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
 
 
TM5
 
 
 
 
 
ICL3
 
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
 
 
TM2
 
 
 
 
 
 
 
 
 
ECL1
 
TM3
 
 
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
C-term
 
 
 
 
 
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
 
 
 
TM5
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
ICL3
 
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
 
 
TM5
 
 
 
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
N-term
 
 
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
 
 
ECL2
 
 
 
 
 
TM5
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
ICL3
 
 
TM6
 
ECL3
 
TM7
 
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
 
 
 
 
 
 
 
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
 
 
 
 
TM5
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
ICL3
 
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
 
 
 
TM5
 
 
 
 
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
 
 
TM5
 
 
 
 
 
ICL3
 
 
 
 
 
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
 
 
 
 
 
TM5
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
ICL3
 
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
C-term
 
N-term
 
 
 
 
 
 
 
 
 
 
TM1
 
 
 
 
ICL1
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
TM2
 
 
 
 
 
 
 
 
 
 
 
ECL1
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
TM3
 
 
 
 
 
ICL2
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
TM4
 
 
 
 
 
 
 
 
 
 
 
 
 
ECL2
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
TM5
 
 
 
 
 
 
 
ICL3
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
TM6
 
 
 
 
ECL3
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
TM7
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
C-term
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
 
 
 
 
 
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
 
 
 
ICL3
 
 
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
C-term
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
 
 
TM5
 
 
 
 
 
ICL3
 
 
 
 
 
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
 
N-term
 
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
 
 
ECL2
 
 
 
 
 
TM5
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
ICL3
 
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
 
 
 
 
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
 
 
TM5
 
 
 
 
 
ICL3
 
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
 
 
 
 
 
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
 
 
 
ICL3
 
 
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
N-term
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
 
 
ICL3
 
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
 
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
 
 
 
 
 
 
 
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
 
 
 
 
 
 
TM5
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
ICL3
 
 
 
TM6
 
ECL3
 
TM7
 
 
H8
 
 
C-term
 
 
 
 
 
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
 
 
 
 
 
TM5
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
ICL3
 
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
 
 
 
 
 
 
 
 
 
 
 
N-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
N-term
 
 
TM1
 
ICL1
 
TM2
 
ECL1
 
 
 
 
 
TM3
 
 
 
ICL2
 
TM4
 
ECL2
 
 
 
 
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
 
 
 
 
H8
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
C-term
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
N-term
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
TM5
 
ICL3
 
TM6
 
ECL3
 
TM7
 
H8
 
C-term
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
N-term
 
 
 
TM1
 
ICL1
 
TM2
 
ECL1
 
TM3
 
ICL2
 
TM4
 
ECL2
 
 
 
 
 
TM5
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
ICL3
 
 
TM6
 
ECL3
 
TM7
 
 
H8